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Protalix BioTherapeutics, Inc.

PLX
Exchange
NYSE
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001006281

No open-market purchases or sales by Protalix BioTherapeutics, Inc. insiders were filed in the last 90 days; 101 institutions reported holding it in 13F filings for Q2 2026, worth $33.7M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Protalix BioTherapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
100
+18 vs. Q4 2025
Shares held
16.9M
+2.45M (+17.0%) vs. Q4 2025
Total value
$36.6M
+$10.6M (+40.9%) vs. Q4 2025
New holders
27
28 more added
Sold out
9
20 more reduced

1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 100 institutions
Q1 2021: 38 institutionsQ2 2021: 33 institutionsQ3 2021: 35 institutionsQ4 2021: 31 institutionsQ1 2022: 32 institutionsQ2 2022: 30 institutionsQ3 2022: 27 institutionsQ4 2022: 26 institutionsQ1 2023: 34 institutionsQ2 2023: 66 institutionsQ3 2023: 61 institutionsQ4 2023: 66 institutionsQ1 2024: 64 institutionsQ2 2024: 66 institutionsQ3 2024: 45 institutionsQ4 2024: 46 institutionsQ1 2025: 63 institutionsQ2 2025: 63 institutionsQ3 2025: 77 institutionsQ4 2025: 83 institutionsQ1 2026: 100 institutionsQ2 2026: 101 institutions
Value heldQ1 2026: $36.6M
Q1 2021: $39.4MQ2 2021: $8.24MQ3 2021: $5.91MQ4 2021: $2.45MQ1 2022: $1.29MQ2 2022: $1.30MQ3 2022: $3.70MQ4 2022: $4.87MQ1 2023: $6.15MQ2 2023: $17.9MQ3 2023: $15.2MQ4 2023: $17.6MQ1 2024: $11.9MQ2 2024: $6.60MQ3 2024: $3.53MQ4 2024: $8.40MQ1 2025: $21.0MQ2 2025: $17.6MQ3 2025: $30.9MQ4 2025: $26.8MQ1 2026: $36.6MQ2 2026: $33.7M
Institutions holding PLX and their total value by quarter
QuarterHoldersValue
Q2 2026101$33.7M
Q1 2026100$36.6M
Q4 202583$26.8M
Q3 202577$30.9M
Q2 202563$17.6M
Q1 202563$21.0M
Q4 202446$8.40M
Q3 202445$3.53M
Q2 202466$6.60M
Q1 202464$11.9M
Q4 202366$17.6M
Q3 202361$15.2M
Q2 202366$17.9M
Q1 202334$6.15M
Q4 202226$4.87M
Q3 202227$3.70M
Q2 202230$1.30M
Q1 202232$1.29M
Q4 202131$2.45M
Q3 202135$5.91M
Q2 202133$8.24M
Q1 202138$39.4M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Protalix BioTherapeutics, Inc.; share changes are against Q4 2025.

Institutions holding PLX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
SBI Securities Co., Ltd.1$20.00%00.0%Unchanged
IFP Advisors, Inc3$70.00%+3New
EverSource Wealth Advisors, LLC11$240.00%+11New
True Wealth Design, LLC11$240.00%+11New
Rothschild Investment LLC15$330.00%+15New
The PNC Financial Services Group, Inc.20$430.00%00.0%Unchanged
Essential Partners LLC26$560.00%+26New
Allworth Financial LP26$570.00%+26New
MAI Capital Management29$630.00%+29New
SRS Capital Advisors, Inc.55$1200.00%+16+41.0%Added
Northwestern Mutual Wealth Management Co100$2170.00%+100New
Root Financial Partners, LLC128$2780.00%+128New
Y.D. More Investments Ltd220$4770.00%00.0%Unchanged
C M Bidwell & Associates Ltd236$5120.00%+236New
Federation des caisses Desjardins du Quebec250$5430.00%00.0%Unchanged
Advisor Group Holdings, Inc.300$6510.00%−900−75.0%Reduced
Activest Wealth Management300$6510.00%00.0%Unchanged
Sterling Capital Management LLC453$9830.00%00.0%Unchanged
GAMMA Investing LLC479$1.04K0.00%+124+34.9%Added
Investment Research & Advisory Group, Inc.1,000$2.17K0.00%00.0%Unchanged
CWM, LLC1,534$3.33K0.00%+1,331+655.7%Added
National Bank of Canada2,000$4.36K0.00%+2,000New
FMR LLC2,905$6.30K0.00%+590+25.5%Added
Citigroup Inc2,958$6.42K0.00%+1,324+81.0%Added
California State Teachers Retirement System3,909$8.48K0.00%−534−12.0%Reduced
Tower Research Capital LLC (TRC)5,158$11.2K0.00%−1,075−17.2%Reduced
TD Waterhouse Canada Inc.6,000$13.0K0.00%00.0%Unchanged
Harbour Investments, Inc.6,000$13.0K0.00%+6,000New
Legal & General Group Plc6,333$13.7K0.00%−868−12.1%Reduced
Baader Bank INC10,046$14.4K0.00%+10,046New
Ameritas Investment Partners, Inc.7,119$15.4K0.00%00.0%Unchanged
Royal Bank of Canada7,568$16.0K0.00%+4,164+122.3%Added
Altshuler Shaham Ltd7,742$16.8K0.00%−4,400−36.2%Reduced
Equitable Holdings, Inc.11,150$20.1K0.00%00.0%Unchanged
Alliancebernstein L.P.11,720$21.1K0.00%00.0%Unchanged
Kestra Advisory Services, LLC10,000$21.7K0.00%00.0%Unchanged
Harbour Investment Management LLC10,100$21.9K0.01%00.0%Unchanged
Prudential Financial Inc10,110$21.9K0.00%+10,110New
LPL Financial LLC10,291$22.3K0.00%00.0%Unchanged
ProShare Advisors LLC10,589$23.0K0.00%−2,548−19.4%Reduced
Voya Investment Management LLC11,494$24.9K0.00%+11,494New
Neuberger Berman Group LLC11,629$25.2K0.00%+11,629New
Cascade Financial Partners, LLC12,000$26.0K0.00%00.0%Unchanged
Russell Investments Group, Ltd.12,250$26.6K0.00%+4,983+68.6%Added
Group One Trading, L.P.13,222$28.7K0.00%+13,222New
Barclays PLC14,822$32.2K0.00%−98,027−86.9%Reduced
Lido Advisors, LLC15,554$33.8K0.00%00.0%Unchanged
Jane Street Group, LLC17,342$37.6K0.00%−272,575−94.0%Reduced
BNP Paribas Arbitrage, SA17,343$37.6K0.00%+322+1.9%Added
Two Sigma Investments, LP18,129$39.3K0.00%+18,129New
Police & Firemen's Retirement System of New Jersey18,554$40.3K0.00%00.0%Unchanged
Prelude Capital Management, LLC18,900$41.0K0.00%−3,343−15.0%Reduced
Commonwealth Equity Services, LLC19,461$42.2K0.00%−152,311−88.7%Reduced
Manufacturers Life Insurance Company, The19,528$42.4K0.00%+1,030+5.6%Added
Intech Investment Management LLC19,958$43.3K0.00%−11,175−35.9%Reduced
State of Alaska, Department of Revenue21,831$47.0K0.00%00.0%Unchanged
Simplex Trading, LLC22,671$49.2K0.00%+22,671New
Smartleaf Asset Management LLC25,975$54.3K0.00%00.0%Unchanged
Capital Performance Advisors LLP26,051$56.5K0.00%+76+0.3%Added
Wells Fargo & Company26,522$57.6K0.00%−52,480−66.4%Reduced
Aptus Capital Advisors, LLC27,231$59.1K0.00%+621+2.3%Added
AQR Capital Management LLC30,493$66.2K0.00%+30,493New
JPMorgan Chase & Co31,685$66.2K0.00%+811+2.6%Added
New York State Common Retirement Fund31,100$67.5K0.00%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.34,062$73.9K0.00%+816+2.5%Added
Phoenix Holdings Ltd.40,000$86.7K0.00%+40,000New
MetLife Investment Management43,697$94.8K0.00%+43,697New
Rhumbline Advisers45,817$99.4K0.00%+1,448+3.3%Added
Invesco Ltd.47,402$102.9K0.00%−3,161−6.3%Reduced
Susquehanna International Group, LLP49,085$106.5K0.00%+10,567+27.4%Added
Price T Rowe Associates Inc53,478$117.0K0.00%+18,200+51.6%Added
Vanguard Fiduciary Trust Co63,351$137.5K0.00%+63,351New
Orin Green Financial, LLC64,433$139.8K0.06%+3,000+4.9%Added
Virtu Financial LLC67,893$147.0K0.01%+67,893New
Deutsche Bank AG74,985$162.7K0.00%+74,139+8,763.5%Added
Bank of America Corp79,079$171.6K0.00%+32,727+70.6%Added
Lazard Asset Management LLC86,617$188.0K0.00%+15,224+21.3%Added
Nuveen, LLC90,188$195.7K0.00%00.0%Unchanged
Diametric Capital, LP124,195$269.5K0.07%−14,734−10.6%Reduced
Charles Schwab Investment Management Inc159,311$345.7K0.00%−15,759−9.0%Reduced
Evergreen Capital Management LLC171,338$371.8K0.01%00.0%Unchanged
Bridgeway Capital Management, LLC189,100$410.3K0.01%00.0%Unchanged
Round Rock Advisors, LLC192,080$416.8K0.06%+36,978+23.8%Added
Connor, Clark & Lunn Investment Management Ltd.207,275$449.8K0.00%−24,818−10.7%Reduced
Main Street Financial Solutions, LLC214,100$464.6K0.03%00.0%Unchanged
Bank of New York Mellon Corp219,307$475.9K0.00%+8,440+4.0%Added
Goldman Sachs Group Inc251,345$545.4K0.00%−11,464−4.4%Reduced
UBS Group AG265,535$576.2K0.00%+3,015+1.1%Added
Dimensional Fund Advisors LP296,843$643.8K0.00%+268,099+932.7%Added
Morgan Stanley301,793$654.9K0.00%+169,806+128.7%Added
Opaleye Management Inc.340,000$737.8K0.10%−2,138,176−86.3%Reduced
Prospera Financial Services Inc418,570$908.3K0.01%+418,570New
Vanguard Portfolio Management LLC432,485$938.5K0.00%+432,485New
Stratos Wealth Partners, LTD.500,000$1.08M0.01%00.0%Unchanged
Geode Capital Management, LLC865,298$1.88M0.00%+35,244+4.2%Added
Northern Trust Corp885,448$1.92M0.00%+19,740+2.3%Added
State Street Corp972,815$2.11M0.00%+387,554+66.2%Added
Renaissance Technologies LLC1,224,800$2.66M0.00%−38,500−3.0%Reduced
Mak Capital One LLC3,544,139$7.69M1.27%+3,544,139New
BlackRock, Inc.3,616,962$7.85M0.00%−30,144−0.8%Reduced