Oruka Therapeutics, Inc.
ORKA- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000907654
In the last 90 days, Oruka Therapeutics, Inc. insiders filed 0 open-market purchases and 14 sales; 255 institutions reported holding it in 13F filings for Q2 2026, worth $7.05B in total; Viking Global Investors is the only superinvestor holding it.
13F holders, Q4 2025
Institutional positions in Oruka Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 143
- +38 vs. Q3 2025
- Shares held
- 52.9M
- +7.29M (+16.0%) vs. Q3 2025
- Total value
- $1.60B
- +$726.2M (+82.9%) vs. Q3 2025
- New holders
- 46
- 54 more added
- Sold out
- 8
- 16 more reduced
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ORKA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 255 | $7.05B |
| Q1 2026 | 184 | $2.55B |
| Q4 2025 | 143 | $1.60B |
| Q3 2025 | 105 | $875.8M |
| Q2 2025 | 81 | $386.0M |
| Q1 2025 | 71 | $326.1M |
| Q4 2024 | 66 | $606.6M |
| Q3 2024 | 42 | $604.2M |
| Q2 2024 | 32 | $49.4M |
| Q1 2024 | 23 | $12.7M |
| Q4 2023 | 25 | $12.7M |
| Q3 2023 | 21 | $6.55M |
| Q2 2023 | 23 | $5.75M |
| Q1 2023 | 26 | $5.02M |
| Q4 2022 | 22 | $6.19M |
| Q3 2022 | 25 | $4.58M |
| Q2 2022 | 24 | $4.17M |
| Q1 2022 | 22 | $2.60M |
| Q4 2021 | 21 | $2.41M |
| Q3 2021 | 19 | $4.53M |
| Q2 2021 | 17 | $4.16M |
| Q1 2021 | 17 | $3.20M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Oruka Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Kalehua Capital Management LLC | 118,524 | $3.59M | 3.55% | +118,524 | New |
| Deutsche Bank AG | 119,329 | $3.62M | 0.00% | +97,210+439.5% | Added |
| Morgan Stanley | 122,198 | $3.70M | 0.00% | −12,635−9.4% | Reduced |
| Moody Aldrich Partners LLC | 126,812 | $3.84M | 0.72% | +126,812 | New |
| Longaeva Partners L.P. | 128,110 | $3.88M | 0.46% | +128,110 | New |
| Bank of America Corp | 139,272 | $4.22M | 0.00% | +60,277+76.3% | Added |
| Invesco Ltd. | 143,121 | $4.34M | 0.00% | +126,803+777.1% | Added |
| Barclays PLC | 173,329 | $5.25M | 0.00% | +77,999+81.8% | Added |
| Great Point Partners LLC | 183,330 | $5.56M | 1.80% | 00.0% | Unchanged |
| Soleus Capital Management, L.P. | 190,000 | $5.76M | 0.24% | +190,000 | New |
| UBS Group AG | 271,013 | $8.21M | 0.00% | +184,453+213.1% | Added |
| Northern Trust Corp | 280,904 | $8.51M | 0.00% | +61,195+27.9% | Added |
| Charles Schwab Investment Management Inc | 329,496 | $9.99M | 0.00% | +82,570+33.4% | Added |
| Cable Car Capital LLC | 400,000 | $12.1M | 0.75% | −100,000−20.0% | Reduced |
| Candriam Luxembourg S.C.A. | 400,509 | $12.1M | 0.06% | +33,515+9.1% | Added |
| Sr One Capital Management, LP | 430,330 | $13.0M | 1.85% | 00.0% | Unchanged |
| Synergy Financial Management, LLC | 458,946 | $13.9M | 1.45% | +458,946 | New |
| Cormorant Asset Management, LP | 533,340 | $16.2M | 0.92% | 00.0% | Unchanged |
| Woodline Partners LP | 574,553 | $17.4M | 0.07% | +2230.0% | Added |
| Point72 Asset Management, L.P. | 600,000 | $18.2M | 0.03% | −437,002−42.1% | Reduced |
| Price T Rowe Associates Inc | 649,346 | $19.7M | 0.00% | +22,540+3.6% | Added |
| Avidity Partners Management LP | 660,424 | $20.0M | 5.77% | 00.0% | Unchanged |
| Citadel Advisors LLC | 726,118 | $22.0M | 0.01% | +409,232+129.1% | Added |
| Mercer Global Advisors Inc | 745,277 | $22.6M | 0.03% | −107,134−12.6% | Reduced |
| Affinity Asset Advisors, LLC | 802,342 | $24.3M | 1.75% | −156,838−16.4% | Reduced |
| Franklin Resources Inc | 938,421 | $28.4M | 0.01% | −127,361−12.0% | Reduced |
| Geode Capital Management, LLC | 942,507 | $28.6M | 0.00% | +252,535+36.6% | Added |
| Polar Capital Holdings Plc | 978,288 | $29.7M | 0.14% | −54,019−5.2% | Reduced |
| Blackstone Group Inc. | 1,165,408 | $35.3M | 0.15% | +315,008+37.0% | Added |
| Avoro Capital Advisors LLC | 1,333,340 | $40.4M | 0.40% | 00.0% | Unchanged |
| State Street Corp | 1,383,847 | $41.9M | 0.00% | +731,819+112.2% | Added |
| Perceptive Advisors LLC | 1,476,501 | $44.8M | 0.82% | +208,480+16.4% | Added |
| Remedium Capital Partners, LLC | 1,552,414 | $47.1M | 27.64% | +1,552,414 | New |
| Paradigm Biocapital Advisors LP | 1,710,316 | $51.8M | 1.39% | +1,710,316 | New |
| Commodore Capital LP | 1,753,054 | $53.1M | 3.54% | 00.0% | Unchanged |
| RTW Investments, LP | 2,058,148 | $62.4M | 0.62% | +112,499+5.8% | Added |
| Deep Track Capital, LP | 2,161,510 | $65.5M | 1.49% | −493,271−18.6% | Reduced |
| Vanguard Group Inc | 2,453,530 | $74.4M | 0.00% | +676,865+38.1% | Added |
| Viking Global Investors LPSuperinvestorViking Global Investors | 2,666,690 | $80.8M | 0.21% | 00.0% | Unchanged |
| BlackRock, Inc. | 3,539,415 | $107.3M | 0.00% | +1,334,864+60.6% | Added |
| Fairmount Funds Management LLC | 3,705,262 | $112.3M | 8.55% | 00.0% | Unchanged |
| VR Adviser, LLC | 4,148,428 | $125.7M | 6.21% | 00.0% | Unchanged |
| FMR LLC | 7,261,384 | $220.1M | 0.01% | +3,763+0.1% | Added |
| Jefferies Financial Group Inc. | 0 | $0 | 0.00% | −64,991−100.0% | Sold out |
| Toronto Dominion Bank | 0 | $0 | 0.00% | −58,332−100.0% | Sold out |
| Caption Management, LLC | 0 | $0 | 0.00% | −2,000−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −729−100.0% | Sold out |
| SRS Capital Advisors, Inc. | 0 | $0 | 0.00% | −72−100.0% | Sold out |
| Rise Advisors, LLC | 0 | $0 | 0.00% | −36−100.0% | Sold out |
| National Bank of Canada | 0 | $0 | 0.00% | −8−100.0% | Sold out |
| SBI Securities Co., Ltd. | 0 | $0 | 0.00% | −6−100.0% | Sold out |