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Maze Therapeutics, Inc.

MAZE
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001842295

In the last 90 days, Maze Therapeutics, Inc. insiders filed 0 open-market purchases and 11 sales; 161 institutions reported holding it in 13F filings for Q2 2026, worth $1.75B in total; HHLR Advisors (Hillhouse) is the only superinvestor holding it.

13F holders, Q1 2026

Institutional positions in Maze Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
165
+24 vs. Q4 2025
Shares held
51.7M
+5.01M (+10.7%) vs. Q4 2025
Total value
$1.54B
−$390.0M (−20.2%) vs. Q4 2025
New holders
49
58 more added
Sold out
25
36 more reduced

2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MAZE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 165 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 68 institutionsQ2 2025: 75 institutionsQ3 2025: 94 institutionsQ4 2025: 143 institutionsQ1 2026: 165 institutionsQ2 2026: 161 institutions
Value heldQ1 2026: $1.54B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $441.4MQ2 2025: $476.7MQ3 2025: $1.11BQ4 2025: $2.00BQ1 2026: $1.54BQ2 2026: $1.75B
Institutions holding MAZE and their total value by quarter
QuarterHoldersValue
Q2 2026161$1.75B
Q1 2026165$1.54B
Q4 2025143$2.00B
Q3 202594$1.11B
Q2 202575$476.7M
Q1 202568$441.4M
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Maze Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding MAZE in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Nuveen, LLC63,360$1.89M0.00%+6,102+10.7%Added
Raymond James Financial Inc69,375$2.07M0.00%+1,657+2.4%Added
Bank of New York Mellon Corp74,268$2.22M0.00%+13,832+22.9%Added
SummitTX Capital, L.P.83,750$2.50M0.08%+14,190+20.4%Added
Invesco Ltd.86,419$2.58M0.00%−47,614−35.5%Reduced
Exome Asset Management LLC88,510$2.64M1.55%+88,510New
Alliancebernstein L.P.64,762$2.68M0.00%+31,542+94.9%Added
UBS Group AG93,898$2.80M0.00%+65,200+227.2%Added
HighVista Strategies LLC99,850$2.98M0.82%−70,503−41.4%Reduced
Alyeska Investment Group, L.P.100,000$2.98M0.01%−96,124−49.0%Reduced
Integral Health Asset Management, LLC100,000$2.98M0.16%00.0%Unchanged
Ameriprise Financial Inc107,486$3.21M0.00%+10,798+11.2%Added
Atika Capital Management LLC111,500$3.33M0.53%+111,500New
Price T Rowe Associates Inc122,695$3.66M0.00%+6,984+6.0%Added
Qube Research & Technologies Ltd134,950$4.03M0.01%+134,950New
Holocene Advisors, LP136,168$4.06M0.01%+136,168New
Vanguard Fiduciary Trust Co151,000$4.51M0.00%+151,000New
Foresite Capital Management IV, LLC156,901$4.68M1.98%−365,756−70.0%Reduced
Ensign Peak Advisors, Inc185,794$5.55M0.01%00.0%Unchanged
Charles Schwab Investment Management Inc186,433$5.57M0.00%+10,464+5.9%Added
Bank of America Corp195,084$5.82M0.00%+176,703+961.3%Added
Vanguard Portfolio Management LLC195,542$5.84M0.00%+195,542New
Spruce Street Capital LP200,000$5.97M1.44%+200,000New
Morgan Stanley204,831$6.11M0.00%−53,255−20.6%Reduced
Northern Trust Corp211,382$6.31M0.00%+35,123+19.9%Added
Standard Life Aberdeen plc226,227$6.75M0.01%+226,227New
Sphera Funds Management Ltd.227,343$6.79M1.17%+155,500+216.4%Added
Freestone Grove Partners LP234,953$7.01M0.05%+116,077+97.6%Added
Mass General Brigham, Inc239,994$7.16M1.53%00.0%Unchanged
Squadron Capital Management LLC257,500$7.69M3.08%−232,500−47.4%Reduced
Candriam Luxembourg S.C.A.278,167$8.30M0.04%+278,167New
Goldman Sachs Group Inc279,713$8.35M0.00%+165,258+144.4%Added
Washington University280,802$8.38M5.23%00.0%Unchanged
Boothbay Fund Management, LLC284,476$8.49M0.20%−124,896−30.5%Reduced
Marshall Wace, LLP310,639$9.27M0.01%−536,833−63.3%Reduced
HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse)366,028$10.9M0.65%−91,507−20.0%Reduced
Farallon Capital Management, L.L.C.373,000$11.1M0.07%+373,000New
Ikarian Capital, LLC378,999$11.3M1.62%−265,681−41.2%Reduced
Balyasny Asset Management LLC461,151$13.8M0.03%+261,939+131.5%Added
Bessemer Group Inc481,790$14.4M0.02%00.0%Unchanged
Geode Capital Management, LLC599,967$17.9M0.00%+72,686+13.8%Added
Caligan Partners LP614,962$18.4M1.30%+64,771+11.8%Added
Driehaus Capital Management LLC636,162$19.0M0.14%+258,147+68.3%Added
State Street Corp636,722$19.0M0.00%+103,717+19.5%Added
Woodline Partners LP650,229$19.4M0.07%−385,000−37.2%Reduced
Cormorant Asset Management, LP750,000$22.4M1.13%+750,000New
Casdin Capital, LLC758,857$22.7M1.72%00.0%Unchanged
ArrowMark Colorado Holdings LLC767,383$22.9M0.61%00.0%Unchanged
Citadel Advisors LLC775,714$23.2M0.02%+327,497+73.1%Added
FMR LLC864,214$25.8M0.00%+135,609+18.6%Added
TRV GP V, LLC950,800$28.4M7.08%00.0%Unchanged
General Catalyst Group Management, LLC1,035,910$30.9M16.85%00.0%Unchanged
Adage Capital Partners GP, L.L.C.1,178,000$35.2M0.05%+1,178,000New
Logos Global Management LP1,235,000$36.9M1.90%+285,000+30.0%Added
Alphabet Inc.1,388,583$41.4M1.03%00.0%Unchanged
Vanguard Capital Management LLC1,435,656$42.9M0.00%+1,435,656New
VR Adviser, LLC1,602,034$47.8M1.78%+53,465+3.5%Added
AH Capital Management, L.L.C.1,702,225$50.8M3.94%00.0%Unchanged
BlackRock, Inc.2,570,425$76.7M0.00%+283,270+12.4%Added
Paradigm Biocapital Advisors LP2,744,399$81.9M1.67%+2,744,399New
Janus Henderson Group PLC2,858,876$85.3M0.04%−283,711−9.0%Reduced
Deep Track Capital, LP3,477,562$103.8M2.14%−768,878−18.1%Reduced
ARCH Venture Management, LLC4,120,053$123.0M18.16%00.0%Unchanged
TRV GP IV, LLC4,473,958$133.5M50.04%00.0%Unchanged
Frazier Life Sciences Management, L.P.4,567,274$136.3M3.51%00.0%Unchanged
Bellevue Group AG0$00.00%−887,708−100.0%Sold out
Matrix Capital Management Company, LP0$00.00%−480,000−100.0%Sold out
Eventide Asset Management, LLC0$00.00%−324,041−100.0%Sold out
TCG Crossover Management, LLC0$00.00%−173,816−100.0%Sold out
StemPoint Capital LP0$00.00%−125,877−100.0%Sold out
MPM Oncology Impact Management LP0$00.00%−81,145−100.0%Sold out
Trexquant Investment LP0$00.00%−52,459−100.0%Sold out
Seven Grand Managers, LLC0$00.00%−50,000−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−48,200−100.0%Sold out
Cinctive Capital Management LP0$00.00%−29,134−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−24,059−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−14,800−100.0%Sold out
PSP Research LLC0$00.00%−12,672−100.0%Sold out
SG Americas Securities, LLC0$00.00%−8,493−100.0%Sold out
Landscape Capital Management, L.L.C.0$00.00%−6,050−100.0%Sold out
ProShare Advisors LLC0$00.00%−6,047−100.0%Sold out
Profund Advisors LLC0$00.00%−6,016−100.0%Sold out
SEI Investments Co0$00.00%−5,668−100.0%Sold out
Rafferty Asset Management, LLC0$00.00%−5,244−100.0%Sold out
Quantbot Technologies LP0$00.00%−5,221−100.0%Sold out
WestHill Financial Advisors, Inc.0$00.00%−5,186−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−5,042−100.0%Sold out
Amalgamated Bank0$00.00%−674−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−160−100.0%Sold out
SageView Advisory Group, LLC0$00.00%−54−100.0%Sold out
Vanguard Group Inc––––Not filed
CIBC Private Wealth Group, LLC––––Not filed