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CytomX Therapeutics, Inc.

CTMX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001501989

No open-market purchases or sales by CytomX Therapeutics, Inc. insiders were filed in the last 90 days; 178 institutions reported holding it in 13F filings for Q2 2026, worth $799.0M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in CytomX Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
103
+20 vs. Q2 2025
Shares held
137.4M
+4.12M (+3.1%) vs. Q2 2025
Total value
$438.4M
+$135.8M (+44.9%) vs. Q2 2025
New holders
32
29 more added
Sold out
12
25 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CTMX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 103 institutions
Q1 2021: 126 institutionsQ2 2021: 122 institutionsQ3 2021: 114 institutionsQ4 2021: 110 institutionsQ1 2022: 119 institutionsQ2 2022: 99 institutionsQ3 2022: 84 institutionsQ4 2022: 81 institutionsQ1 2023: 76 institutionsQ2 2023: 67 institutionsQ3 2023: 62 institutionsQ4 2023: 68 institutionsQ1 2024: 88 institutionsQ2 2024: 74 institutionsQ3 2024: 69 institutionsQ4 2024: 70 institutionsQ1 2025: 66 institutionsQ2 2025: 83 institutionsQ3 2025: 103 institutionsQ4 2025: 122 institutionsQ1 2026: 179 institutionsQ2 2026: 178 institutions
Value heldQ3 2025: $438.4M
Q1 2021: $422.2MQ2 2021: $358.9MQ3 2021: $274.8MQ4 2021: $236.5MQ1 2022: $143.4MQ2 2022: $83.4MQ3 2022: $52.6MQ4 2022: $57.5MQ1 2023: $53.7MQ2 2023: $58.7MQ3 2023: $41.8MQ4 2023: $50.6MQ1 2024: $97.1MQ2 2024: $61.9MQ3 2024: $60.4MQ4 2024: $48.1MQ1 2025: $28.8MQ2 2025: $302.6MQ3 2025: $438.4MQ4 2025: $613.9MQ1 2026: $911.2MQ2 2026: $799.0M
Institutions holding CTMX and their total value by quarter
QuarterHoldersValue
Q2 2026178$799.0M
Q1 2026179$911.2M
Q4 2025122$613.9M
Q3 2025103$438.4M
Q2 202583$302.6M
Q1 202566$28.8M
Q4 202470$48.1M
Q3 202469$60.4M
Q2 202474$61.9M
Q1 202488$97.1M
Q4 202368$50.6M
Q3 202362$41.8M
Q2 202367$58.7M
Q1 202376$53.7M
Q4 202281$57.5M
Q3 202284$52.6M
Q2 202299$83.4M
Q1 2022119$143.4M
Q4 2021110$236.5M
Q3 2021114$274.8M
Q2 2021122$358.9M
Q1 2021126$422.2M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding CytomX Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding CTMX in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Tower Research Capital LLC (TRC)3$100.00%−29,658−100.0%Reduced
BNP Paribas Arbitrage, SA17$540.00%00.0%Unchanged
SBI Securities Co., Ltd.85$2710.00%+1+1.2%Added
Advisory Services Network, LLC274$8740.00%+274New
Caitong International Asset Management Co., Ltd689$2.20K0.00%−967−58.4%Reduced
Barclays PLC1,490$4.75K0.00%+1,488+74,400.0%Added
Wells Fargo & Company3,605$11.5K0.00%+3,605New
Truist Financial Corp12,500$12.6K0.00%+12,500New
Private Wealth Asset Management, LLC4,000$12.8K0.00%00.0%Unchanged
Citigroup Inc7,756$24.7K0.00%+7,756New
Farther Finance Advisors, LLC7,970$25.4K0.00%+7,970New
Peregrine Asset Advisers, Inc.10,000$31.9K0.01%00.0%Unchanged
Meridian Wealth Management, LLC10,000$31.9K0.00%00.0%Unchanged
Mariner, LLC10,250$32.7K0.00%+10,250New
Bay Colony Advisory Group, Inc d/b/a Bay Colony Advisors10,747$34.3K0.00%+10,747New
IPG Investment Advisors LLC12,500$39.9K0.01%00.0%Unchanged
Nierenberg Investment Management Company, Inc.12,555$40.0K0.02%00.0%Unchanged
Victory Capital Management Inc14,121$45.0K0.00%+1,686+13.6%Added
Icapital Wealth LLC14,492$46.2K0.03%00.0%Unchanged
JPMorgan Chase & Co16,152$51.5K0.00%+15,871+5,648.0%Added
BIT Capital GmbH16,285$51.9K0.00%+16,285New
Advisor Group Holdings, Inc.16,710$52.8K0.00%+500+3.1%Added
WestHill Financial Advisors, Inc.17,082$54.5K0.01%00.0%Unchanged
Truvestments Capital LLC17,101$54.6K0.01%+2,233+15.0%Added
Forefront Analytics, LLC18,109$57.8K0.06%−9,589−34.6%Reduced
Forefront Wealth Partners, LLC18,109$57.8K0.01%+18,109New
Invesco Ltd.22,426$71.5K0.00%+8,255+58.3%Added
BlueChip Wealth Advisors LLC23,000$73.4K0.03%+23,000New
Prudential Financial Inc23,300$74.3K0.00%−2,400−9.3%Reduced
Ethos Financial Group, LLC23,697$75.6K0.01%+23,697New
JustInvest LLC26,939$85.9K0.00%−2,027−7.0%Reduced
XTX Topco Ltd29,286$93.4K0.00%−92,613−76.0%Reduced
UBS Group AG30,168$96.2K0.00%−377,867−92.6%Reduced
Jain Global LLC33,652$107.3K0.00%+33,652New
Sanctuary Advisors, LLC34,634$110.5K0.00%+34,634New
Two Sigma Advisers, LP40,000$127.6K0.00%+40,000New
Persistent Asset Partners Ltd42,645$136.0K0.10%+42,645New
Private Advisor Group, LLC44,002$140.4K0.00%00.0%Unchanged
Squarepoint Ops LLC47,728$152.3K0.00%−1,664−3.4%Reduced
Susquehanna Portfolio Strategies, LLC48,012$153.2K0.00%−51,398−51.7%Reduced
Jacobs Levy Equity Management, Inc50,773$162.0K0.00%+50,773New
Jefferies Financial Group Inc.52,914$168.8K0.00%+52,914New
Merit Financial Group, LLC53,243$169.8K0.00%+53,243New
Miller Financial Services LLC67,000$213.7K0.25%+16,000+31.4%Added
Velan Capital Investment Management LP80,000$255.2K0.24%+5,000+6.7%Added
LPL Financial LLC86,653$276.4K0.00%−114,571−56.9%Reduced
Charles Schwab Investment Management Inc88,570$282.5K0.00%00.0%Unchanged
Aspire Growth Partners LLC102,254$326.2K0.24%00.0%Unchanged
Congress Park Capital LLC103,922$331.5K0.10%+8,500+8.9%Added
Formidable Asset Management, LLC118,337$377.5K0.06%−194,513−62.2%Reduced
Toroso Investments, LLC118,337$377.5K0.00%−194,513−62.2%Reduced
Qube Research & Technologies Ltd122,500$390.8K0.00%+122,500New
Stonepine Capital Management, LLC125,000$398.8K0.32%+125,000New
Quadrature Capital Ltd125,035$398.9K0.00%+125,035New
Royal Bank of Canada152,304$486.0K0.00%−91,243−37.5%Reduced
Ameriprise Financial Inc158,329$505.1K0.00%+158,329New
Diadema Partners LP185,286$591.1K0.41%+185,286New
Prelude Capital Management, LLC206,526$658.8K0.05%+206,526New
Precision Wealth Strategies, LLC237,081$756.3K0.25%+237,081New
Bank of New York Mellon Corp252,659$806.0K0.00%00.0%Unchanged
HighVista Strategies LLC257,148$820.3K0.20%+257,148New
Susquehanna International Group, LLP267,485$853.3K0.00%−24,411−8.4%Reduced
Raymond James Financial Inc293,560$936.5K0.00%+10,000+3.5%Added
Morgan Stanley319,288$1.02M0.00%−19,918−5.9%Reduced
Northern Trust Corp389,685$1.24M0.00%−60,422−13.4%Reduced
Jane Street Group, LLC401,367$1.28M0.00%+389,399+3,253.7%Added
First Trust Advisors LP401,891$1.28M0.00%+401,891New
Goldman Sachs Group Inc447,753$1.43M0.00%+433,075+2,950.5%Added
Dimensional Fund Advisors LP451,128$1.44M0.00%+267,962+146.3%Added
CWM Advisors, LLC522,482$1.67M0.16%+522,482New
Gsa Capital Partners LLP535,974$1.71M0.14%−94,835−15.0%Reduced
Prosight Management, LP564,800$1.80M0.43%−2,952,313−83.9%Reduced
State Street Corp644,982$2.06M0.00%+5,942+0.9%Added
Acadian Asset Management LLC653,725$2.08M0.00%−903,311−58.0%Reduced
Two Sigma Investments, LP729,698$2.33M0.00%+572,017+362.8%Added
Assenagon Asset Management S.A.729,967$2.33M0.00%+9,947+1.4%Added
Exome Asset Management LLC745,305$2.38M1.57%+745,305New
Bank of America Corp1,005,228$3.21M0.00%+1,000,457+20,969.5%Added
Marshall Wace, LLP1,104,993$3.52M0.00%−1,248,129−53.0%Reduced
Boothbay Fund Management, LLC1,237,057$3.95M0.10%+1,237,057New
Financial Engines Advisors L.L.C.1,381,357$4.41M0.01%+1,381,357New
Millennium Management LLC1,386,863$4.42M0.00%+1,153,524+494.4%Added
Geode Capital Management, LLC1,569,298$5.01M0.00%−175,878−10.1%Reduced
Citadel Advisors LLC1,800,435$5.74M0.00%+1,714,926+2,005.6%Added
Woodline Partners LP2,337,005$7.46M0.04%+1060.0%Added
BlackRock, Inc.2,381,912$7.60M0.00%−6,541−0.3%Reduced
Renaissance Technologies LLC2,545,260$8.12M0.01%+683,060+36.7%Added
Ra Capital Management, L.P.2,661,331$8.49M0.10%00.0%Unchanged
Vivo Capital, LLC2,884,615$9.20M0.74%−2,884,615−50.0%Reduced
Ikarian Capital, LLC3,372,616$10.8M2.44%+3,372,616New
RTW Investments, LP3,461,500$11.0M0.14%00.0%Unchanged
Kynam Capital Management, LP3,646,503$11.6M0.87%+1,492,090+69.3%Added
Balyasny Asset Management LLC3,913,081$12.5M0.03%+1,047,456+36.6%Added
ADAR1 Capital Management, LLC4,045,414$12.9M1.28%+964,000+31.3%Added
Point72 Asset Management, L.P.4,068,575$13.0M0.03%−4,016,048−49.7%Reduced
Baker Bros. Advisors LP4,250,826$13.6M0.10%+766,600+22.0%Added
Commodore Capital LP7,692,300$24.5M1.20%00.0%Unchanged
OrbiMed Advisors LLC8,461,500$27.0M0.65%00.0%Unchanged
Vanguard Group Inc8,947,807$28.5M0.00%−431,987−4.6%Reduced
Perceptive Advisors LLC9,680,185$30.9M0.89%+2,686,539+38.4%Added