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CytomX Therapeutics, Inc.

CTMX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001501989

No open-market purchases or sales by CytomX Therapeutics, Inc. insiders were filed in the last 90 days; 178 institutions reported holding it in 13F filings for Q2 2026, worth $799.0M in total; no superinvestor holds it.

Holders of 5% or more of CTMX

Holders whose latest Schedule 13D or 13G filing reports 5% or more of CytomX Therapeutics, Inc., largest stake first. The change is against the holder's previous filing.

Holders of 5% or more of CTMX
HolderLatest formStakeChangeFirst filedLatest filingFiling
FMR LLC13G/A14.60%24.7M shares+2.20 ppfrom 12.40%Aug 6, 20254 filingsFeb 5, 2026SEC
Kynam Capital Management, LP13G/A9.96%0 shares+3.06 ppfrom 6.90%Mar 4, 20263 filingsAug 14, 2026SEC
BlackRock, Inc.13G7.60%16.6M sharesNewJul 27, 20261 filingJul 27, 2026SEC
Longitude Capital Partners V, LLC13G/A7.00%15.3M shares−0.30 ppfrom 7.30%May 20, 20252 filingsMay 15, 2026SEC
Bank of America Corp13G7.00%15.1M sharesNewAug 3, 20261 filingAug 3, 2026SEC
State Street Corp13G5.40%11.7M sharesNewAug 7, 20261 filingAug 7, 2026SEC

Stakes are as of each holder's latest filing. Holders whose last filing was in the old format (before December 18, 2024) have no stake on record and are not listed, and after an acquisition or delisting holders usually stop filing.

13D and 13G filings

50 Schedule 13D and 13G filings on CytomX Therapeutics, Inc., newest first, including old-format filings without a stake.

Schedule 13D and 13G filings on CTMX
Filed (ET)FilerFormStakeChangeEvent dateFiling
Aug 14, 20264:06 PM ETPoint72 Asset Management, L.P.and 2 others13G/A3.60%7.81M shares−1.40 ppfrom 5.00%Below 5%Jun 30, 2026SEC
Aug 14, 202612:11 PM ETKynam Capital Management, LPand 2 others13G/A9.96%0 shares+3.06 ppfrom 6.90%Jun 30, 2026SEC
Aug 7, 20269:20 AM ETState Street Corp13G5.40%11.7M sharesNewJun 30, 2026SEC
Aug 3, 202612:05 PM ETBank of America Corp13G7.00%15.1M sharesNewJun 30, 2026SEC
Jul 27, 20264:25 PM ETBlackRock, Inc.13G7.60%16.6M sharesNewJun 30, 2026SEC
May 15, 20265:09 PM ETSeven Fleet Capital Management LPand 3 others13G/A0.50%1.09M shares+0.48 ppfrom 0.02%Below 5%Mar 31, 2026SEC
May 15, 20264:46 PM ETLongitude Capital Partners V, LLCand 5 others13G/A7.00%15.3M shares−0.30 ppfrom 7.30%Mar 31, 2026SEC
May 15, 20264:36 PM ETVenrock Healthcare Capital Partners III, L.P.and 6 others13G/A4.60%9.98M shares−4.80 ppfrom 9.40%Below 5%Mar 31, 2026SEC
May 15, 20264:01 PM ETKynam Capital Management, LPand 2 others13G/A6.90%0 shares+1.61 ppfrom 5.29%Mar 31, 2026SEC
May 15, 20264:00 PM ETPerceptive Advisors LLCand 2 others13G/A4.60%10.1M shares−1.30 ppfrom 5.90%Below 5%Mar 31, 2026SEC
Apr 16, 20264:10 PM ETPoint72 Asset Management, L.P.and 2 others13G5.00%10.9M shares+2.50 ppfrom 2.50%Apr 15, 2026SEC
Mar 26, 20265:40 PM ETVanguard Group Inc13G/A0.00%0 shares−5.95 ppfrom 5.95%Below 5%Mar 13, 2026SEC
Mar 4, 20263:18 PM ETKynam Capital Management, LPand 2 others13G5.29%8.97M sharesNewDec 31, 2025SEC
Feb 17, 20266:23 PM ETOrbiMed Advisors LLC13G/A2.10%3.53M shares−3.30 ppfrom 5.40%Below 5%Dec 31, 2025SEC
Feb 17, 20264:15 PM ETTang Capital Management LLCand 5 others13G/A0.00%0 shares−7.00 ppfrom 7.00%Below 5%Dec 31, 2025SEC
Feb 5, 20261:20 PM ETFMR LLCand 1 other13G/A14.60%24.7M shares+2.20 ppfrom 12.40%Dec 31, 2025SEC
Nov 14, 20255:30 PM ETVenrock Healthcare Capital Partners III, L.P.and 6 others13G/A9.40%15.6M shares+1.20 ppfrom 8.20%Sep 30, 2025SEC
Nov 14, 20254:08 PM ETPoint72 Asset Management, L.P.and 2 others13G/A2.50%4.07M shares−2.60 ppfrom 5.10%Below 5%Sep 30, 2025SEC
Nov 14, 202512:04 PM ETSeven Fleet Capital Management LPand 3 others13G/A0.02%48.9K shares–Below 5%Sep 30, 2025SEC
Nov 7, 202511:13 AM ETFMR LLCand 1 other13G/A12.40%20.5M shares+3.10 ppfrom 9.30%Oct 31, 2025SEC
Nov 5, 202511:30 AM ETFMR LLCand 1 other13G/A9.30%15.4M shares+3.40 ppfrom 5.90%Sep 30, 2025SEC
Aug 21, 20254:00 PM ETPerceptive Advisors LLCand 2 others13G5.90%9.68M shares–Aug 14, 2025SEC
Aug 14, 20256:07 PM ETOrbiMed Advisors LLC13G5.40%8.46M sharesNewJun 30, 2025SEC
Aug 14, 20255:30 PM ETPoint72 Asset Management, L.P.and 2 others13G/A5.10%8.08M shares−3.20 ppfrom 8.30%Jun 30, 2025SEC
Aug 14, 20254:15 PM ETTang Capital Management LLCand 5 others13G/A7.00%11.1M shares−1.40 ppfrom 8.40%Jun 30, 2025SEC
Aug 6, 202511:56 AM ETFMR LLCand 1 other13G5.90%9.24M sharesNewJun 30, 2025SEC
Jul 29, 202511:22 AM ETVanguard Group Inc13G/A5.95%9.38M shares–Jun 30, 2025SEC
Jul 9, 20257:55 PM ETBiotechnology Value Fund L Pand 9 others13G/A3.50%5.77M shares−3.30 ppfrom 6.80%Below 5%Jul 3, 2025SEC
Jul 9, 20257:53 PM ETBiotechnology Value Fund L Pand 9 others13G/A6.80%11.5M shares–Jun 30, 2025SEC
May 20, 20259:02 PM ETSeven Fleet Partners LPand 2 others13G0.20%377.2K sharesNewBelow 5%May 13, 2025SEC
May 20, 20259:00 PM ETLongitude Capital Partners V, LLCand 3 others13G7.30%11.5M sharesNewMay 13, 2025SEC
May 20, 20254:25 PM ETVenrock Healthcare Capital Partners III, L.P.and 6 others13G8.20%13.0M sharesNewMay 13, 2025SEC
May 15, 20254:15 PM ETTang Capital Management LLCand 5 others13G/A8.40%6.72M shares–Mar 31, 2025SEC
May 14, 20255:14 PM ETPoint72 Asset Management, L.P.and 2 others13G8.30%13.1M shares–May 12, 2025SEC
Feb 14, 202511:34 AM ETJanus Henderson Group PLC13G/A0.00%0 shares–Below 5%Dec 31, 2024SEC
Feb 14, 2022Ra Capital Management, L.P.13G/AOld format–––SEC
Feb 14, 2022RTW Investments, LP13G/AOld format–––SEC
Feb 14, 2022Point72 Asset Management, L.P.13G/AOld format–––SEC
Feb 9, 2022Vanguard Group Inc13G/AOld format–––SEC
Feb 1, 2022Victory Capital Management Inc13G/AOld format–––SEC
Jan 3, 2022Biotechnology Value Fund L P13GOld format–––SEC
Dec 8, 2021RTW Investments, LP13GOld format–New–SEC
May 3, 2021Biotechnology Value Fund L P13G/AOld format–––SEC
Feb 16, 2021Perceptive Advisors LLC13G/AOld format–––SEC
Feb 11, 2021Biotechnology Value Fund L P13G/AOld format–––SEC
Feb 10, 2021Vanguard Group Inc13G/AOld format–––SEC
Feb 2, 2021Victory Capital Management Inc13G/AOld format–––SEC
Jan 29, 20219:56 AM ETBlackRock Inc.13G/AOld format–––SEC
Jan 29, 2021Ra Capital Management, L.P.13GOld format–New–SEC
Jan 26, 2021Point72 Asset Management, L.P.13GOld format–New–SEC

Form 144: proposed insider sales

Notices from officers, directors and other affiliates planning to sell CytomX Therapeutics, Inc. shares.

No Form 144 notices for CytomX Therapeutics, Inc. are on file.