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CytomX Therapeutics, Inc.

CTMX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001501989

No open-market purchases or sales by CytomX Therapeutics, Inc. insiders were filed in the last 90 days; 178 institutions reported holding it in 13F filings for Q2 2026, worth $799.0M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in CytomX Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
103
+20 vs. Q2 2025
Shares held
137.4M
+4.12M (+3.1%) vs. Q2 2025
Total value
$438.4M
+$135.8M (+44.9%) vs. Q2 2025
New holders
32
29 more added
Sold out
12
25 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CTMX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 103 institutions
Q1 2021: 126 institutionsQ2 2021: 122 institutionsQ3 2021: 114 institutionsQ4 2021: 110 institutionsQ1 2022: 119 institutionsQ2 2022: 99 institutionsQ3 2022: 84 institutionsQ4 2022: 81 institutionsQ1 2023: 76 institutionsQ2 2023: 67 institutionsQ3 2023: 62 institutionsQ4 2023: 68 institutionsQ1 2024: 88 institutionsQ2 2024: 74 institutionsQ3 2024: 69 institutionsQ4 2024: 70 institutionsQ1 2025: 66 institutionsQ2 2025: 83 institutionsQ3 2025: 103 institutionsQ4 2025: 122 institutionsQ1 2026: 179 institutionsQ2 2026: 178 institutions
Value heldQ3 2025: $438.4M
Q1 2021: $422.2MQ2 2021: $358.9MQ3 2021: $274.8MQ4 2021: $236.5MQ1 2022: $143.4MQ2 2022: $83.4MQ3 2022: $52.6MQ4 2022: $57.5MQ1 2023: $53.7MQ2 2023: $58.7MQ3 2023: $41.8MQ4 2023: $50.6MQ1 2024: $97.1MQ2 2024: $61.9MQ3 2024: $60.4MQ4 2024: $48.1MQ1 2025: $28.8MQ2 2025: $302.6MQ3 2025: $438.4MQ4 2025: $613.9MQ1 2026: $911.2MQ2 2026: $799.0M
Institutions holding CTMX and their total value by quarter
QuarterHoldersValue
Q2 2026178$799.0M
Q1 2026179$911.2M
Q4 2025122$613.9M
Q3 2025103$438.4M
Q2 202583$302.6M
Q1 202566$28.8M
Q4 202470$48.1M
Q3 202469$60.4M
Q2 202474$61.9M
Q1 202488$97.1M
Q4 202368$50.6M
Q3 202362$41.8M
Q2 202367$58.7M
Q1 202376$53.7M
Q4 202281$57.5M
Q3 202284$52.6M
Q2 202299$83.4M
Q1 2022119$143.4M
Q4 2021110$236.5M
Q3 2021114$274.8M
Q2 2021122$358.9M
Q1 2021126$422.2M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding CytomX Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding CTMX in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
VR Adviser, LLC15,561,500$49.6M2.79%+1,591,618+11.4%Added
FMR LLC15,396,200$49.1M0.00%+6,157,332+66.6%Added
Tang Capital Management LLC11,065,662$35.3M1.36%00.0%Unchanged
Perceptive Advisors LLC9,680,185$30.9M0.89%+2,686,539+38.4%Added
Vanguard Group Inc8,947,807$28.5M0.00%−431,987−4.6%Reduced
OrbiMed Advisors LLC8,461,500$27.0M0.65%00.0%Unchanged
Commodore Capital LP7,692,300$24.5M1.20%00.0%Unchanged
Baker Bros. Advisors LP4,250,826$13.6M0.10%+766,600+22.0%Added
Point72 Asset Management, L.P.4,068,575$13.0M0.03%−4,016,048−49.7%Reduced
ADAR1 Capital Management, LLC4,045,414$12.9M1.28%+964,000+31.3%Added
Balyasny Asset Management LLC3,913,081$12.5M0.03%+1,047,456+36.6%Added
Kynam Capital Management, LP3,646,503$11.6M0.87%+1,492,090+69.3%Added
RTW Investments, LP3,461,500$11.0M0.14%00.0%Unchanged
Ikarian Capital, LLC3,372,616$10.8M2.44%+3,372,616New
Vivo Capital, LLC2,884,615$9.20M0.74%−2,884,615−50.0%Reduced
Ra Capital Management, L.P.2,661,331$8.49M0.10%00.0%Unchanged
Renaissance Technologies LLC2,545,260$8.12M0.01%+683,060+36.7%Added
BlackRock, Inc.2,381,912$7.60M0.00%−6,541−0.3%Reduced
Woodline Partners LP2,337,005$7.46M0.04%+1060.0%Added
Citadel Advisors LLC1,800,435$5.74M0.00%+1,714,926+2,005.6%Added
Geode Capital Management, LLC1,569,298$5.01M0.00%−175,878−10.1%Reduced
Millennium Management LLC1,386,863$4.42M0.00%+1,153,524+494.4%Added
Financial Engines Advisors L.L.C.1,381,357$4.41M0.01%+1,381,357New
Boothbay Fund Management, LLC1,237,057$3.95M0.10%+1,237,057New
Marshall Wace, LLP1,104,993$3.52M0.00%−1,248,129−53.0%Reduced
Bank of America Corp1,005,228$3.21M0.00%+1,000,457+20,969.5%Added
Exome Asset Management LLC745,305$2.38M1.57%+745,305New
Assenagon Asset Management S.A.729,967$2.33M0.00%+9,947+1.4%Added
Two Sigma Investments, LP729,698$2.33M0.00%+572,017+362.8%Added
Acadian Asset Management LLC653,725$2.08M0.00%−903,311−58.0%Reduced
State Street Corp644,982$2.06M0.00%+5,942+0.9%Added
Prosight Management, LP564,800$1.80M0.43%−2,952,313−83.9%Reduced
Gsa Capital Partners LLP535,974$1.71M0.14%−94,835−15.0%Reduced
CWM Advisors, LLC522,482$1.67M0.16%+522,482New
Dimensional Fund Advisors LP451,128$1.44M0.00%+267,962+146.3%Added
Goldman Sachs Group Inc447,753$1.43M0.00%+433,075+2,950.5%Added
First Trust Advisors LP401,891$1.28M0.00%+401,891New
Jane Street Group, LLC401,367$1.28M0.00%+389,399+3,253.7%Added
Northern Trust Corp389,685$1.24M0.00%−60,422−13.4%Reduced
Morgan Stanley319,288$1.02M0.00%−19,918−5.9%Reduced
Raymond James Financial Inc293,560$936.5K0.00%+10,000+3.5%Added
Susquehanna International Group, LLP267,485$853.3K0.00%−24,411−8.4%Reduced
HighVista Strategies LLC257,148$820.3K0.20%+257,148New
Bank of New York Mellon Corp252,659$806.0K0.00%00.0%Unchanged
Precision Wealth Strategies, LLC237,081$756.3K0.25%+237,081New
Prelude Capital Management, LLC206,526$658.8K0.05%+206,526New
Diadema Partners LP185,286$591.1K0.41%+185,286New
Ameriprise Financial Inc158,329$505.1K0.00%+158,329New
Royal Bank of Canada152,304$486.0K0.00%−91,243−37.5%Reduced
Quadrature Capital Ltd125,035$398.9K0.00%+125,035New
Stonepine Capital Management, LLC125,000$398.8K0.32%+125,000New
Qube Research & Technologies Ltd122,500$390.8K0.00%+122,500New
Formidable Asset Management, LLC118,337$377.5K0.06%−194,513−62.2%Reduced
Toroso Investments, LLC118,337$377.5K0.00%−194,513−62.2%Reduced
Congress Park Capital LLC103,922$331.5K0.10%+8,500+8.9%Added
Aspire Growth Partners LLC102,254$326.2K0.24%00.0%Unchanged
Charles Schwab Investment Management Inc88,570$282.5K0.00%00.0%Unchanged
LPL Financial LLC86,653$276.4K0.00%−114,571−56.9%Reduced
Velan Capital Investment Management LP80,000$255.2K0.24%+5,000+6.7%Added
Miller Financial Services LLC67,000$213.7K0.25%+16,000+31.4%Added
Merit Financial Group, LLC53,243$169.8K0.00%+53,243New
Jefferies Financial Group Inc.52,914$168.8K0.00%+52,914New
Jacobs Levy Equity Management, Inc50,773$162.0K0.00%+50,773New
Susquehanna Portfolio Strategies, LLC48,012$153.2K0.00%−51,398−51.7%Reduced
Squarepoint Ops LLC47,728$152.3K0.00%−1,664−3.4%Reduced
Private Advisor Group, LLC44,002$140.4K0.00%00.0%Unchanged
Persistent Asset Partners Ltd42,645$136.0K0.10%+42,645New
Two Sigma Advisers, LP40,000$127.6K0.00%+40,000New
Sanctuary Advisors, LLC34,634$110.5K0.00%+34,634New
Jain Global LLC33,652$107.3K0.00%+33,652New
UBS Group AG30,168$96.2K0.00%−377,867−92.6%Reduced
XTX Topco Ltd29,286$93.4K0.00%−92,613−76.0%Reduced
JustInvest LLC26,939$85.9K0.00%−2,027−7.0%Reduced
Ethos Financial Group, LLC23,697$75.6K0.01%+23,697New
Prudential Financial Inc23,300$74.3K0.00%−2,400−9.3%Reduced
BlueChip Wealth Advisors LLC23,000$73.4K0.03%+23,000New
Invesco Ltd.22,426$71.5K0.00%+8,255+58.3%Added
Forefront Analytics, LLC18,109$57.8K0.06%−9,589−34.6%Reduced
Forefront Wealth Partners, LLC18,109$57.8K0.01%+18,109New
Truvestments Capital LLC17,101$54.6K0.01%+2,233+15.0%Added
WestHill Financial Advisors, Inc.17,082$54.5K0.01%00.0%Unchanged
Advisor Group Holdings, Inc.16,710$52.8K0.00%+500+3.1%Added
BIT Capital GmbH16,285$51.9K0.00%+16,285New
JPMorgan Chase & Co16,152$51.5K0.00%+15,871+5,648.0%Added
Icapital Wealth LLC14,492$46.2K0.03%00.0%Unchanged
Victory Capital Management Inc14,121$45.0K0.00%+1,686+13.6%Added
Nierenberg Investment Management Company, Inc.12,555$40.0K0.02%00.0%Unchanged
IPG Investment Advisors LLC12,500$39.9K0.01%00.0%Unchanged
Bay Colony Advisory Group, Inc d/b/a Bay Colony Advisors10,747$34.3K0.00%+10,747New
Mariner, LLC10,250$32.7K0.00%+10,250New
Peregrine Asset Advisers, Inc.10,000$31.9K0.01%00.0%Unchanged
Meridian Wealth Management, LLC10,000$31.9K0.00%00.0%Unchanged
Farther Finance Advisors, LLC7,970$25.4K0.00%+7,970New
Citigroup Inc7,756$24.7K0.00%+7,756New
Private Wealth Asset Management, LLC4,000$12.8K0.00%00.0%Unchanged
Truist Financial Corp12,500$12.6K0.00%+12,500New
Wells Fargo & Company3,605$11.5K0.00%+3,605New
Barclays PLC1,490$4.75K0.00%+1,488+74,400.0%Added
Caitong International Asset Management Co., Ltd689$2.20K0.00%−967−58.4%Reduced
Advisory Services Network, LLC274$8740.00%+274New