CytomX Therapeutics, Inc.
CTMX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001501989
No open-market purchases or sales by CytomX Therapeutics, Inc. insiders were filed in the last 90 days; 178 institutions reported holding it in 13F filings for Q2 2026, worth $799.0M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in CytomX Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 122
- +19 vs. Q3 2025
- Shares held
- 144.1M
- +6.67M (+4.9%) vs. Q3 2025
- Total value
- $613.9M
- +$175.5M (+40.0%) vs. Q3 2025
- New holders
- 39
- 39 more added
- Sold out
- 20
- 25 more reduced
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CTMX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 178 | $799.0M |
| Q1 2026 | 179 | $911.2M |
| Q4 2025 | 122 | $613.9M |
| Q3 2025 | 103 | $438.4M |
| Q2 2025 | 83 | $302.6M |
| Q1 2025 | 66 | $28.8M |
| Q4 2024 | 70 | $48.1M |
| Q3 2024 | 69 | $60.4M |
| Q2 2024 | 74 | $61.9M |
| Q1 2024 | 88 | $97.1M |
| Q4 2023 | 68 | $50.6M |
| Q3 2023 | 62 | $41.8M |
| Q2 2023 | 67 | $58.7M |
| Q1 2023 | 76 | $53.7M |
| Q4 2022 | 81 | $57.5M |
| Q3 2022 | 84 | $52.6M |
| Q2 2022 | 99 | $83.4M |
| Q1 2022 | 119 | $143.4M |
| Q4 2021 | 110 | $236.5M |
| Q3 2021 | 114 | $274.8M |
| Q2 2021 | 122 | $358.9M |
| Q1 2021 | 126 | $422.2M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding CytomX Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 24,688,109 | $105.2M | 0.01% | +9,291,909+60.4% | Added |
| VR Adviser, LLC | 15,561,500 | $66.3M | 3.27% | 00.0% | Unchanged |
| Perceptive Advisors LLC | 9,680,185 | $41.2M | 0.76% | 00.0% | Unchanged |
| Kynam Capital Management, LP | 8,966,077 | $38.2M | 2.49% | +5,319,574+145.9% | Added |
| Vanguard Group Inc | 8,475,584 | $36.1M | 0.00% | −472,223−5.3% | Reduced |
| Commodore Capital LP | 7,692,300 | $32.8M | 2.18% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 5,189,538 | $22.1M | 0.03% | +1,120,963+27.6% | Added |
| State Street Corp | 5,140,931 | $21.9M | 0.00% | +4,495,949+697.1% | Added |
| Baker Bros. Advisors LP | 4,250,826 | $18.1M | 0.11% | 00.0% | Unchanged |
| ADAR1 Capital Management, LLC | 4,182,769 | $17.8M | 1.33% | +137,355+3.4% | Added |
| Balyasny Asset Management LLC | 3,872,202 | $16.5M | 0.03% | −40,879−1.0% | Reduced |
| Financial Engines Advisors L.L.C. | 3,828,717 | $16.3M | 0.03% | +2,447,360+177.2% | Added |
| BlackRock, Inc. | 3,669,393 | $15.6M | 0.00% | +1,287,481+54.1% | Added |
| OrbiMed Advisors LLC | 3,525,650 | $15.0M | 0.31% | −4,935,850−58.3% | Reduced |
| Ikarian Capital, LLC | 3,172,616 | $13.5M | 1.75% | −200,000−5.9% | Reduced |
| Vivo Capital, LLC | 2,884,615 | $12.3M | 0.79% | 00.0% | Unchanged |
| Eversept Partners, LP | 2,507,090 | $10.7M | 0.60% | +2,507,090 | New |
| Goldman Sachs Group Inc | 2,460,944 | $10.5M | 0.00% | +2,013,191+449.6% | Added |
| Woodline Partners LP | 2,337,005 | $9.96M | 0.04% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 1,560,755 | $6.65M | 0.01% | +831,057+113.9% | Added |
| Geode Capital Management, LLC | 1,525,666 | $6.50M | 0.00% | −43,632−2.8% | Reduced |
| Dimensional Fund Advisors LP | 1,289,656 | $5.49M | 0.00% | +838,528+185.9% | Added |
| Marshall Wace, LLP | 1,156,936 | $4.93M | 0.00% | +51,943+4.7% | Added |
| Qube Research & Technologies Ltd | 1,061,128 | $4.52M | 0.01% | +938,628+766.2% | Added |
| StemPoint Capital LP | 1,036,311 | $4.41M | 0.76% | +1,036,311 | New |
| Susquehanna International Group, LLP | 981,598 | $4.18M | 0.01% | +714,113+267.0% | Added |
| Boothbay Fund Management, LLC | 894,663 | $3.81M | 0.10% | −342,394−27.7% | Reduced |
| Bank of America Corp | 876,305 | $3.73M | 0.00% | −128,923−12.8% | Reduced |
| Acadian Asset Management LLC | 856,056 | $3.64M | 0.01% | +202,331+31.0% | Added |
| Exome Asset Management LLC | 745,305 | $3.17M | 1.57% | 00.0% | Unchanged |
| Elmind Capital, LP | 700,000 | $2.98M | 0.88% | +700,000 | New |
| Jane Street Group, LLC | 607,218 | $2.59M | 0.00% | +205,851+51.3% | Added |
| Assenagon Asset Management S.A. | 592,696 | $2.52M | 0.00% | −137,271−18.8% | Reduced |
| First Trust Advisors LP | 423,168 | $1.80M | 0.00% | +21,277+5.3% | Added |
| Northern Trust Corp | 415,178 | $1.77M | 0.00% | +25,493+6.5% | Added |
| Morgan Stanley | 401,191 | $1.71M | 0.00% | +81,903+25.7% | Added |
| Silverarc Capital Management, LLC | 385,974 | $1.64M | 0.24% | +385,974 | New |
| Schulhoff & Co Inc | 374,850 | $1.60M | 0.67% | +374,850 | New |
| UBS Group AG | 370,739 | $1.58M | 0.00% | +340,571+1,128.9% | Added |
| Citadel Advisors LLC | 342,304 | $1.46M | 0.00% | −1,458,131−81.0% | Reduced |
| Barclays PLC | 336,525 | $1.43M | 0.00% | +335,035+22,485.6% | Added |
| Two Sigma Advisers, LP | 335,524 | $1.43M | 0.00% | +295,524+738.8% | Added |
| Bank of New York Mellon Corp | 328,248 | $1.40M | 0.00% | +75,589+29.9% | Added |
| Raymond James Financial Inc | 316,971 | $1.35M | 0.00% | +23,411+8.0% | Added |
| Millennium Management LLC | 289,653 | $1.23M | 0.00% | −1,097,210−79.1% | Reduced |
| Rafferty Asset Management, LLC | 273,584 | $1.17M | 0.00% | +273,584 | New |
| Ameriprise Financial Inc | 229,599 | $989.0K | 0.00% | +71,270+45.0% | Added |
| Prelude Capital Management, LLC | 206,526 | $879.8K | 0.06% | 00.0% | Unchanged |
| EAM Investors, LLC | 203,823 | $868.3K | 0.10% | +203,823 | New |
| HighVista Strategies LLC | 193,941 | $826.2K | 0.21% | −63,207−24.6% | Reduced |
| SEI Investments Co | 124,124 | $528.8K | 0.00% | +124,124 | New |
| LPL Financial LLC | 113,440 | $483.3K | 0.00% | +26,787+30.9% | Added |
| Canada Pension Plan Investment Board | 104,200 | $443.9K | 0.00% | +104,200 | New |
| Aspire Growth Partners LLC | 102,254 | $435.6K | 0.30% | 00.0% | Unchanged |
| NLB Skladi, upravljanje premozenja, d.o.o. | 100,000 | $426.0K | 0.02% | +100,000 | New |
| Profund Advisors LLC | 98,633 | $420.2K | 0.01% | +98,633 | New |
| Citigroup Inc | 96,326 | $410.3K | 0.00% | +88,570+1,142.0% | Added |
| Omers Administration Corp | 87,800 | $374.0K | 0.00% | +87,800 | New |
| Gsa Capital Partners LLP | 81,886 | $349.0K | 0.03% | −454,088−84.7% | Reduced |
| Velan Capital Investment Management LP | 80,000 | $340.8K | 0.20% | 00.0% | Unchanged |
| HRT Financial LP | 71,867 | $306.0K | 0.00% | +71,867 | New |
| Charles Schwab Investment Management Inc | 68,687 | $292.6K | 0.00% | −19,883−22.4% | Reduced |
| Miller Financial Services LLC | 68,000 | $289.7K | 0.34% | +1,000+1.5% | Added |
| Virtus Investment Advisers, Inc. | 63,491 | $270.5K | 0.07% | +63,491 | New |
| Skopos Labs, Inc. | 61,474 | $257.6K | 0.01% | +61,474 | New |
| Congress Park Capital LLC | 58,922 | $251.0K | 0.07% | −45,000−43.3% | Reduced |
| Merit Financial Group, LLC | 53,243 | $226.8K | 0.00% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 53,109 | $226.0K | 0.00% | +53,109 | New |
| Timothy G. Youngquist 2020 Irrevocable Trust | 51,155 | $217.9K | 0.19% | +51,155 | New |
| Hudson Bay Capital Management LP | 50,990 | $217.2K | 0.00% | +50,990 | New |
| Squarepoint Ops LLC | 49,897 | $212.6K | 0.00% | +2,169+4.5% | Added |
| Seven Fleet Capital Management LP | 48,898 | $208.3K | 0.14% | +48,898 | New |
| Susquehanna Portfolio Strategies, LLC | 48,012 | $204.5K | 0.00% | 00.0% | Unchanged |
| XTX Topco Ltd | 47,991 | $204.4K | 0.01% | +18,705+63.9% | Added |
| Formidable Asset Management, LLC | 45,763 | $194.9K | 0.03% | −72,574−61.3% | Reduced |
| Toroso Investments, LLC | 45,763 | $194.9K | 0.00% | −72,574−61.3% | Reduced |
| Baader Bank INC | 45,000 | $191.7K | 0.02% | +45,000 | New |
| Private Advisor Group, LLC | 44,002 | $187.4K | 0.00% | 00.0% | Unchanged |
| Lighthouse Investment Partners, LLC | 32,040 | $136.5K | 0.00% | +32,040 | New |
| Cambria Investment Management, L.P. | 31,332 | $133.5K | 0.01% | +31,332 | New |
| Empowered Funds, LLC | 31,332 | $133.5K | 0.00% | +31,332 | New |
| China Universal Asset Management Co., Ltd. | 27,609 | $117.6K | 0.01% | +27,609 | New |
| Truvestments Capital LLC | 27,428 | $116.8K | 0.02% | +10,327+60.4% | Added |
| JustInvest LLC | 26,765 | $114.0K | 0.00% | −174−0.6% | Reduced |
| Engineers Gate Manager LP | 26,539 | $113.1K | 0.00% | +26,539 | New |
| Mangrove Partners | 26,265 | $111.9K | 0.01% | +26,265 | New |
| HB Wealth Management, LLC | 25,000 | $106.5K | 0.00% | +25,000 | New |
| Tower Research Capital LLC (TRC) | 24,794 | $105.6K | 0.00% | +24,791+826,366.7% | Added |
| JPMorgan Chase & Co | 24,363 | $103.8K | 0.00% | +8,211+50.8% | Added |
| Simplex Trading, LLC | 24,051 | $102.5K | 0.00% | +24,051 | New |
| Jefferies Financial Group Inc. | 23,764 | $101.2K | 0.00% | −29,150−55.1% | Reduced |
| Ethos Financial Group, LLC | 23,697 | $100.9K | 0.01% | 00.0% | Unchanged |
| Mariner, LLC | 22,180 | $94.5K | 0.00% | +11,930+116.4% | Added |
| Invesco Ltd. | 21,976 | $93.6K | 0.00% | −450−2.0% | Reduced |
| State of Wyoming | 21,511 | $91.6K | 0.01% | +21,511 | New |
| Jain Global LLC | 21,212 | $90.4K | 0.00% | −12,440−37.0% | Reduced |
| Advisor Group Holdings, Inc. | 19,410 | $82.7K | 0.00% | +2,700+16.2% | Added |
| Sanctuary Advisors, LLC | 19,140 | $81.5K | 0.00% | −15,494−44.7% | Reduced |
| Forefront Analytics, LLC | 18,699 | $79.7K | 0.07% | +590+3.3% | Added |
| Twinbeech Capital LP | 17,600 | $75.0K | 0.01% | +17,600 | New |