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CytomX Therapeutics, Inc.

CTMX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001501989

No open-market purchases or sales by CytomX Therapeutics, Inc. insiders were filed in the last 90 days; 178 institutions reported holding it in 13F filings for Q2 2026, worth $799.0M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in CytomX Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
179
+58 vs. Q4 2025
Shares held
193.9M
+58.3M (+43.0%) vs. Q4 2025
Total value
$911.2M
+$333.5M (+57.7%) vs. Q4 2025
New holders
77
59 more added
Sold out
19
28 more reduced

1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CTMX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 179 institutions
Q1 2021: 126 institutionsQ2 2021: 122 institutionsQ3 2021: 114 institutionsQ4 2021: 110 institutionsQ1 2022: 119 institutionsQ2 2022: 99 institutionsQ3 2022: 84 institutionsQ4 2022: 81 institutionsQ1 2023: 76 institutionsQ2 2023: 67 institutionsQ3 2023: 62 institutionsQ4 2023: 68 institutionsQ1 2024: 88 institutionsQ2 2024: 74 institutionsQ3 2024: 69 institutionsQ4 2024: 70 institutionsQ1 2025: 66 institutionsQ2 2025: 83 institutionsQ3 2025: 103 institutionsQ4 2025: 122 institutionsQ1 2026: 179 institutionsQ2 2026: 178 institutions
Value heldQ1 2026: $911.2M
Q1 2021: $422.2MQ2 2021: $358.9MQ3 2021: $274.8MQ4 2021: $236.5MQ1 2022: $143.4MQ2 2022: $83.4MQ3 2022: $52.6MQ4 2022: $57.5MQ1 2023: $53.7MQ2 2023: $58.7MQ3 2023: $41.8MQ4 2023: $50.6MQ1 2024: $97.1MQ2 2024: $61.9MQ3 2024: $60.4MQ4 2024: $48.1MQ1 2025: $28.8MQ2 2025: $302.6MQ3 2025: $438.4MQ4 2025: $613.9MQ1 2026: $911.2MQ2 2026: $799.0M
Institutions holding CTMX and their total value by quarter
QuarterHoldersValue
Q2 2026178$799.0M
Q1 2026179$911.2M
Q4 2025122$613.9M
Q3 2025103$438.4M
Q2 202583$302.6M
Q1 202566$28.8M
Q4 202470$48.1M
Q3 202469$60.4M
Q2 202474$61.9M
Q1 202488$97.1M
Q4 202368$50.6M
Q3 202362$41.8M
Q2 202367$58.7M
Q1 202376$53.7M
Q4 202281$57.5M
Q3 202284$52.6M
Q2 202299$83.4M
Q1 2022119$143.4M
Q4 2021110$236.5M
Q3 2021114$274.8M
Q2 2021122$358.9M
Q1 2021126$422.2M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding CytomX Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding CTMX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC31,955,637$150.2M0.01%+7,267,528+29.4%Added
Kynam Capital Management, LP15,013,093$70.6M4.48%+6,047,016+67.4%Added
Bank of America Corp10,202,785$48.0M0.00%+9,326,480+1,064.3%Added
Perceptive Advisors LLC10,098,824$47.5M0.94%+418,639+4.3%Added
VR Adviser, LLC9,982,124$46.9M1.75%−5,579,376−35.9%Reduced
Vanguard Capital Management LLC8,733,118$41.0M0.00%+8,733,118New
Point72 Asset Management, L.P.7,875,390$37.0M0.06%+2,685,852+51.8%Added
State Street Corp5,663,408$26.6M0.00%+522,477+10.2%Added
Citadel Advisors LLC5,406,193$25.4M0.02%+5,063,889+1,479.4%Added
BlackRock, Inc.5,228,280$24.6M0.00%+1,558,887+42.5%Added
Baker Bros. Advisors LP4,975,826$23.4M0.13%+725,000+17.1%Added
Elmind Capital, LP4,550,000$21.4M6.07%+3,850,000+550.0%Added
Nextech Invest, Ltd.4,449,932$20.9M1.47%+4,449,932New
Marshall Wace, LLP4,138,176$19.4M0.02%+2,981,240+257.7%Added
Millennium Management LLC3,660,190$17.2M0.01%+3,370,537+1,163.6%Added
Wellington Management Group LLP3,582,985$16.8M0.00%+3,582,985New
Siren, L.L.C.3,457,711$16.3M0.45%+3,457,711New
ADAR1 Capital Management, LLC3,410,190$16.0M0.96%−772,579−18.5%Reduced
Eversept Partners, LP3,188,514$15.0M0.99%+681,424+27.2%Added
UBS Group AG3,120,155$14.7M0.00%+2,749,416+741.6%Added
Jefferies Financial Group Inc.3,067,864$14.4M0.18%+3,044,100+12,809.7%Added
Two Sigma Investments, LP2,710,156$12.7M0.01%+1,149,401+73.6%Added
Qube Research & Technologies Ltd2,249,583$10.6M0.02%+1,188,455+112.0%Added
Geode Capital Management, LLC2,066,612$9.72M0.00%+540,946+35.5%Added
Woodline Partners LP2,000,825$9.40M0.04%−336,180−14.4%Reduced
Dimensional Fund Advisors LP1,930,920$9.07M0.00%+641,264+49.7%Added
Susquehanna International Group, LLP1,869,615$8.79M0.01%+888,017+90.5%Added
Goldman Sachs Group Inc1,459,839$6.86M0.00%−1,001,105−40.7%Reduced
Gilder Gagnon Howe & Co LLC1,120,309$5.27M0.06%+1,120,309New
Vanguard Fiduciary Trust Co1,102,883$5.18M0.00%+1,102,883New
Patient Square Capital LP1,085,790$5.10M0.91%+1,085,790New
Seven Fleet Capital Management LP1,085,398$5.10M1.60%+1,036,500+2,119.7%Added
Jane Street Group, LLC997,510$4.69M0.01%+390,292+64.3%Added
Eventide Asset Management, LLC900,000$4.23M0.07%+900,000New
Ally Bridge Group (NY) LLC900,000$4.23M4.20%+900,000New
Trexquant Investment LP898,767$4.22M0.03%+898,767New
Vanguard Portfolio Management LLC794,755$3.74M0.00%+794,755New
Balyasny Asset Management LLC730,844$3.43M0.01%−3,141,358−81.1%Reduced
DV Trading LLC714,000$3.36M0.30%+714,000New
Northern Trust Corp612,141$2.88M0.00%+196,963+47.4%Added
BNP Paribas Arbitrage, SA606,275$2.85M0.00%+603,450+21,361.1%Added
Ensign Peak Advisors, Inc592,473$2.78M0.01%+592,473New
Caption Management, LLC573,224$2.69M0.13%+573,224New
First Trust Advisors LP568,562$2.67M0.00%+145,394+34.4%Added
EAM Investors, LLC565,113$2.66M0.31%+361,290+177.3%Added
Longaeva Partners L.P.550,000$2.58M0.12%+550,000New
Velan Capital Investment Management LP540,000$2.54M1.59%+460,000+575.0%Added
Exome Asset Management LLC521,468$2.45M1.44%−223,837−30.0%Reduced
Morgan Stanley520,495$2.45M0.00%+119,304+29.7%Added
Schulhoff & Co Inc477,550$2.24M0.92%+102,700+27.4%Added
Deutsche Bank AG463,421$2.18M0.00%+463,421New
683 Capital Management, LLC425,000$2.00M0.19%+425,000New
Raymond James Financial Inc380,160$1.79M0.00%+63,189+19.9%Added
Assenagon Asset Management S.A.364,173$1.71M0.00%−228,523−38.6%Reduced
Seven Grand Managers, LLC325,000$1.53M0.10%+325,000New
Swiss National Bank319,600$1.50M0.00%+319,600New
Soleus Capital Management, L.P.300,000$1.41M0.06%+300,000New
Bank of New York Mellon Corp289,868$1.36M0.00%−38,380−11.7%Reduced
HighVista Strategies LLC288,057$1.35M0.37%+94,116+48.5%Added
Brevan Howard Capital Management LP269,202$1.27M0.01%+257,798+2,260.6%Added
Simplex Trading, LLC248,438$1.17M0.04%+224,387+933.0%Added
SEI Investments Co248,248$1.17M0.00%+124,124+100.0%Added
Toroso Investments, LLC245,768$1.16M0.00%+200,005+437.0%Added
Squarepoint Ops LLC241,215$1.13M0.00%+191,318+383.4%Added
Rafferty Asset Management, LLC239,824$1.13M0.00%−33,760−12.3%Reduced
LMR Partners LLP234,931$1.10M0.01%+234,931New
Scientech Research LLC230,598$1.08M0.90%+230,598New
DAFNA Capital Management LLC230,000$1.08M0.25%+230,000New
Tema ETFs LLC227,505$1.07M0.07%+227,505New
Burkehill Global Management, LP225,000$1.06M0.05%+225,000New
Sphera Funds Management Ltd.220,000$1.03M0.18%+220,000New
Stonepine Capital Management, LLC200,000$940.0K0.83%+200,000New
Centiva Capital, LP200,000$940.0K0.04%+200,000New
UBS Asset Management Americas Inc189,400$890.2K0.00%+189,400New
Y-Intercept (Hong Kong) Ltd167,514$787.3K0.01%+167,514New
Group One Trading, L.P.154,134$724.4K0.02%+154,134New
AWM Investment Company, Inc.150,000$705.0K0.08%+150,000New
Barclays PLC142,412$669.3K0.00%−194,113−57.7%Reduced
Legal & General Group Plc141,893$666.9K0.00%+141,893New
Charles Schwab Investment Management Inc128,796$605.3K0.00%+60,109+87.5%Added
Vanguard Asset Management, Ltd122,893$577.6K0.00%+122,893New
LPL Financial LLC122,634$576.4K0.00%+9,194+8.1%Added
Prelude Capital Management, LLC121,912$573.0K0.04%−84,614−41.0%Reduced
NLB Skladi, upravljanje premozenja, d.o.o.111,111$522.2K0.03%+11,111+11.1%Added
Canada Pension Plan Investment Board108,800$511.4K0.00%+4,600+4.4%Added
Alps Advisors Inc105,820$497.4K0.00%+105,820New
Jain Global LLC104,750$492.3K0.01%+83,538+393.8%Added
Profund Advisors LLC104,535$491.3K0.02%+5,902+6.0%Added
Aspire Growth Partners LLC102,254$480.6K0.33%00.0%Unchanged
Virtu Financial LLC101,895$479.0K0.02%+101,895New
Citigroup Inc101,801$478.5K0.00%+5,475+5.7%Added
Cannon Global Investment Management, LLC96,100$451.7K1.09%+96,100New
Landscape Capital Management, L.L.C.94,240$442.9K0.03%+94,240New
California State Teachers Retirement System88,379$415.4K0.00%+88,379New
Hudson Bay Capital Management LP80,663$379.1K0.00%+29,673+58.2%Added
XTX Topco Ltd77,861$365.9K0.01%+29,870+62.2%Added
Miller Financial Services LLC72,000$338.4K0.38%+4,000+5.9%Added
Vanguard Global Advisers, LLC71,617$336.6K0.00%+71,617New
Jacobs Levy Equity Management, Inc68,378$321.4K0.00%+68,378New
Schonfeld Strategic Advisors LLC67,732$318.3K0.00%+67,732New