C4 Therapeutics, Inc.
CCCC- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001662579
No open-market purchases or sales by C4 Therapeutics, Inc. insiders were filed in the last 90 days; 147 institutions reported holding it in 13F filings for Q2 2026, worth $547.6M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in C4 Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 97
- −5 vs. Q2 2025
- Shares held
- 52.5M
- −2.15M (−3.9%) vs. Q2 2025
- Total value
- $116.6M
- +$38.4M (+49.1%) vs. Q2 2025
- New holders
- 21
- 26 more added
- Sold out
- 26
- 38 more reduced
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CCCC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 147 | $547.6M |
| Q1 2026 | 123 | $221.3M |
| Q4 2025 | 101 | $152.5M |
| Q3 2025 | 97 | $116.6M |
| Q2 2025 | 102 | $78.2M |
| Q1 2025 | 115 | $102.6M |
| Q4 2024 | 113 | $231.8M |
| Q3 2024 | 118 | $365.9M |
| Q2 2024 | 115 | $281.3M |
| Q1 2024 | 106 | $475.6M |
| Q4 2023 | 92 | $265.6M |
| Q3 2023 | 84 | $64.5M |
| Q2 2023 | 100 | $94.1M |
| Q1 2023 | 121 | $117.5M |
| Q4 2022 | 117 | $231.4M |
| Q3 2022 | 114 | $345.9M |
| Q2 2022 | 113 | $297.2M |
| Q1 2022 | 125 | $904.8M |
| Q4 2021 | 119 | $1.15B |
| Q3 2021 | 113 | $1.54B |
| Q2 2021 | 107 | $1.21B |
| Q1 2021 | 83 | $926.8M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding C4 Therapeutics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| CWM, LLC | 146 | $0 | 0.00% | −10,010−98.6% | Reduced |
| IFP Advisors, Inc | 17 | $38 | 0.00% | −17−50.0% | Reduced |
| SRS Capital Advisors, Inc. | 55 | $122 | 0.00% | +55 | New |
| Advisory Services Network, LLC | 74 | $164 | 0.00% | +74 | New |
| Wealthspire Advisors, LLC | 100 | $222 | 0.00% | +100 | New |
| SBI Securities Co., Ltd. | 152 | $337 | 0.00% | +2+1.3% | Added |
| Nisa Investment Advisors, LLC | 156 | $346 | 0.00% | −274−63.7% | Reduced |
| Point72 (DIFC) Ltd | 234 | $519 | 0.00% | −3,719−94.1% | Reduced |
| JFS Wealth Advisors, LLC | 1,000 | $2.22K | 0.00% | +1,000 | New |
| GF Fund Management Co. Ltd. | 1,463 | $3.25K | 0.00% | −288−16.4% | Reduced |
| Rhumbline Advisers | 2,716 | $6.03K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 2,751 | $6.11K | 0.00% | +8+0.3% | Added |
| Citigroup Inc | 3,264 | $7.25K | 0.00% | −19,552−85.7% | Reduced |
| JPMorgan Chase & Co | 4,429 | $9.83K | 0.00% | −177−3.8% | Reduced |
| Advisor Group Holdings, Inc. | 4,530 | $11.3K | 0.00% | +3,030+202.0% | Added |
| Simplex Trading, LLC | 7,836 | $17.0K | 0.00% | +7,836 | New |
| Tower Research Capital LLC (TRC) | 8,414 | $18.7K | 0.00% | −32,178−79.3% | Reduced |
| Squarepoint Ops LLC | 10,099 | $22.4K | 0.00% | −133,588−93.0% | Reduced |
| Abel Hall, LLC | 10,140 | $22.5K | 0.01% | −85−0.8% | Reduced |
| Simplicity Wealth,LLC | 10,213 | $22.7K | 0.00% | +10,213 | New |
| Ethic Inc. | 10,508 | $23.3K | 0.00% | −4,656−30.7% | Reduced |
| National Asset Management, Inc. | 11,000 | $24.4K | 0.00% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 11,863 | $26.3K | 0.00% | −77,612−86.7% | Reduced |
| Group One Trading, L.P. | 12,432 | $27.6K | 0.00% | +12,417+82,780.0% | Added |
| China Universal Asset Management Co., Ltd. | 12,475 | $27.7K | 0.00% | −1,786−12.5% | Reduced |
| Price T Rowe Associates Inc | 12,400 | $28.0K | 0.00% | 00.0% | Unchanged |
| Wolverine Trading, LLC | 12,710 | $28.3K | 0.00% | +12,710 | New |
| Zacks Investment Management | 13,043 | $29.0K | 0.00% | +13,043 | New |
| HSBC Holdings PLC | 13,629 | $30.1K | 0.00% | −11,528−45.8% | Reduced |
| Prudential Financial Inc | 14,300 | $31.7K | 0.00% | +14,300 | New |
| JustInvest LLC | 14,574 | $32.4K | 0.00% | −146−1.0% | Reduced |
| Captrust Financial Advisors | 14,889 | $33.1K | 0.00% | −2,150−12.6% | Reduced |
| Engineers Gate Manager LP | 16,286 | $36.2K | 0.00% | +5,868+56.3% | Added |
| R Squared Ltd | 17,880 | $39.7K | 0.02% | −12,707−41.5% | Reduced |
| Wells Fargo & Company | 18,660 | $41.4K | 0.00% | +17,131+1,120.4% | Added |
| Caitong International Asset Management Co., Ltd | 19,146 | $42.5K | 0.03% | +19,146 | New |
| Ewa, LLC | 19,510 | $43.3K | 0.01% | +2,867+17.2% | Added |
| Commonwealth Equity Services, LLC | 20,510 | $46.0K | 0.00% | −601−2.8% | Reduced |
| Point72 Asia (Singapore) Pte. Ltd. | 21,708 | $48.2K | 0.01% | −21,739−50.0% | Reduced |
| CI Private Wealth, LLC | 22,702 | $50.4K | 0.00% | +10,007+78.8% | Added |
| American Century Companies Inc | 24,248 | $53.8K | 0.00% | +24,248 | New |
| Cresset Asset Management, LLC | 25,000 | $55.5K | 0.00% | 00.0% | Unchanged |
| Farallon Capital Management, L.L.C. | 28,000 | $62.2K | 0.00% | 00.0% | Unchanged |
| Voleon Capital Management LP | 28,420 | $63.1K | 0.00% | +28,420 | New |
| Jefferies Financial Group Inc. | 38,200 | $84.8K | 0.00% | +38,200 | New |
| Graham Capital Management, L.P. | 40,628 | $90.2K | 0.00% | +40,628 | New |
| Catalyst Funds Management Pty Ltd | 42,500 | $94.3K | 0.01% | +14,200+50.2% | Added |
| Barclays PLC | 43,062 | $95.6K | 0.00% | −2,761−6.0% | Reduced |
| UBS Group AG | 61,650 | $136.9K | 0.00% | −510,376−89.2% | Reduced |
| Crestwood Advisors Group LLC | 66,536 | $147.7K | 0.00% | +37,536+129.4% | Added |
| Susquehanna Fundamental Investments, LLC | 67,617 | $150.1K | 0.01% | 00.0% | Unchanged |
| Intrepid Family Office LLC | 70,000 | $155.4K | 0.14% | +30,000+75.0% | Added |
| Bridgeway Capital Management, LLC | 79,900 | $177.4K | 0.00% | −25,000−23.8% | Reduced |
| BNP Paribas Arbitrage, SA | 80,806 | $179.4K | 0.00% | −125,371−60.8% | Reduced |
| State of Wyoming | 82,509 | $183.2K | 0.02% | +82,509 | New |
| Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group | 85,000 | $188.7K | 0.11% | 00.0% | Unchanged |
| Man Group plc | 90,278 | $200.4K | 0.00% | +11,791+15.0% | Added |
| Marshall Wace, LLP | 106,275 | $235.9K | 0.00% | +106,275 | New |
| Algert Global LLC | 106,300 | $236.0K | 0.00% | +106,300 | New |
| Qube Research & Technologies Ltd | 115,973 | $257.5K | 0.00% | +115,973 | New |
| Acadian Asset Management LLC | 128,108 | $282.0K | 0.00% | −11,615−8.3% | Reduced |
| Mariner, LLC | 128,237 | $284.7K | 0.00% | −4,528−3.4% | Reduced |
| Northern Trust Corp | 138,319 | $307.1K | 0.00% | −1,354−1.0% | Reduced |
| Cubist Systematic Strategies, LLC | 138,657 | $307.8K | 0.00% | −101,302−42.2% | Reduced |
| XTX Topco Ltd | 149,962 | $332.9K | 0.02% | +41,684+38.5% | Added |
| Royal Bank of Canada | 182,640 | $405.0K | 0.00% | −56,317−23.6% | Reduced |
| Invesco Ltd. | 191,820 | $425.8K | 0.00% | +36,803+23.7% | Added |
| LPL Financial LLC | 200,930 | $446.1K | 0.00% | +4,675+2.4% | Added |
| Jane Street Group, LLC | 203,568 | $451.9K | 0.00% | −289,044−58.7% | Reduced |
| ArrowMark Colorado Holdings LLC | 204,505 | $454.0K | 0.01% | 00.0% | Unchanged |
| Hennion & Walsh Asset Management, Inc. | 205,033 | $455.2K | 0.02% | −3,733−1.8% | Reduced |
| FMR LLC | 211,348 | $469.2K | 0.00% | +9,990+5.0% | Added |
| Susquehanna Portfolio Strategies, LLC | 272,053 | $604.0K | 0.01% | +145,153+114.4% | Added |
| State Street Corp | 287,373 | $638.0K | 0.00% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 349,289 | $775.5K | 0.00% | −82,599−19.1% | Reduced |
| Charles Schwab Investment Management Inc | 350,606 | $778.3K | 0.00% | +18,709+5.6% | Added |
| Shay Capital LLC | 420,000 | $932.4K | 0.17% | +420,000 | New |
| Goldman Sachs Group Inc | 459,893 | $1.02M | 0.00% | −420,365−47.8% | Reduced |
| Citadel Advisors LLC | 481,449 | $1.07M | 0.00% | +481,449 | New |
| Jacobs Levy Equity Management, Inc | 503,145 | $1.12M | 0.00% | +61,410+13.9% | Added |
| Susquehanna International Group, LLP | 515,437 | $1.14M | 0.00% | +374,381+265.4% | Added |
| Geode Capital Management, LLC | 725,304 | $1.61M | 0.00% | −19,749−2.7% | Reduced |
| Two Sigma Advisers, LP | 763,100 | $1.69M | 0.00% | −48,300−6.0% | Reduced |
| Two Sigma Investments, LP | 834,726 | $1.85M | 0.00% | +151,127+22.1% | Added |
| Tang Capital Management LLC | 900,000 | $2.00M | 0.08% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 936,950 | $2.08M | 0.00% | −156,238−14.3% | Reduced |
| Bain Capital Life Sciences Investors, LLC | 1,111,910 | $2.47M | 0.16% | 00.0% | Unchanged |
| BlackRock, Inc. | 1,595,639 | $3.54M | 0.00% | −232,975−12.7% | Reduced |
| Silverarc Capital Management, LLC | 1,897,383 | $4.21M | 0.61% | +1,897,383 | New |
| Millennium Management LLC | 1,934,225 | $4.29M | 0.00% | +832,883+75.6% | Added |
| Bank of America Corp | 2,053,162 | $4.56M | 0.00% | +45,158+2.2% | Added |
| Vanguard Group Inc | 3,191,557 | $7.09M | 0.00% | +173,535+5.7% | Added |
| Wasatch Advisors Inc | 4,852,741 | $10.8M | 0.06% | −2,571,921−34.6% | Reduced |
| Morgan Stanley | 4,972,032 | $11.0M | 0.00% | +217,844+4.6% | Added |
| OrbiMed Advisors LLC | 5,235,146 | $11.6M | 0.28% | −1,595,154−23.4% | Reduced |
| Soleus Capital Management, L.P. | 7,053,942 | $15.7M | 0.84% | +75,000+1.1% | Added |
| Lynx1 Capital Management LP | 7,098,133 | $15.8M | 3.21% | 00.0% | Unchanged |
| AQR Capital Management LLC | 0 | $0 | 0.00% | −383,789−100.0% | Sold out |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −200,000−100.0% | Sold out |
| Atom Investors LP | 0 | $0 | 0.00% | −190,182−100.0% | Sold out |