Axsome Therapeutics, Inc.
AXSM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001579428
In the last 90 days, Axsome Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 505 institutions reported holding it in 13F filings for Q2 2026, worth $9.34B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Axsome Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 399
- +53 vs. Q3 2025
- Shares held
- 37.6M
- +542.0K (+1.5%) vs. Q3 2025
- Total value
- $6.86B
- +$2.36B (+52.3%) vs. Q3 2025
- New holders
- 87
- 139 more added
- Sold out
- 34
- 122 more reduced
9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AXSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 505 | $9.34B |
| Q1 2026 | 410 | $6.41B |
| Q4 2025 | 399 | $6.86B |
| Q3 2025 | 355 | $4.51B |
| Q2 2025 | 348 | $3.95B |
| Q1 2025 | 353 | $4.37B |
| Q4 2024 | 292 | $3.15B |
| Q3 2024 | 280 | $3.48B |
| Q2 2024 | 257 | $3.28B |
| Q1 2024 | 259 | $3.09B |
| Q4 2023 | 245 | $3.07B |
| Q3 2023 | 227 | $2.65B |
| Q2 2023 | 231 | $2.61B |
| Q1 2023 | 197 | $1.97B |
| Q4 2022 | 219 | $2.32B |
| Q3 2022 | 188 | $1.15B |
| Q2 2022 | 174 | $826.7M |
| Q1 2022 | 175 | $787.4M |
| Q4 2021 | 167 | $704.2M |
| Q3 2021 | 171 | $627.3M |
| Q2 2021 | 176 | $1.51B |
| Q1 2021 | 184 | $1.31B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Axsome Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Rockefeller Capital Management L.P. | 7,453 | $1.36M | 0.00% | +1,716+29.9% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 7,464 | $1.36M | 0.00% | +475+6.8% | Added |
| MONECO Advisors, LLC | 7,505 | $1.37M | 0.11% | 00.0% | Unchanged |
| Two Sigma Securities, LLC | 7,650 | $1.40M | 0.19% | +7,650 | New |
| Element Squared LLC | 8,079 | $1.48M | 0.80% | +8,079 | New |
| Entropy Technologies, LP | 8,192 | $1.50M | 0.08% | +8,192 | New |
| China Universal Asset Management Co., Ltd. | 8,215 | $1.50M | 0.12% | −532−6.1% | Reduced |
| Teachers Retirement System of the State of Kentucky | 8,328 | $1.52M | 0.01% | 00.0% | Unchanged |
| Resources Investment Advisors, LLC. | 8,635 | $1.58M | 0.02% | −1,170−11.9% | Reduced |
| Wesbanco Bank Inc | 8,800 | $1.61M | 0.04% | −4,500−33.8% | Reduced |
| KLP Kapitalforvaltning AS | 9,000 | $1.64M | 0.01% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 9,064 | $1.66M | 0.00% | 00.0% | Unchanged |
| Erste Asset Management GmbH | 11,000 | $1.66M | 0.01% | 00.0% | Unchanged |
| Gsa Capital Partners LLP | 9,117 | $1.67M | 0.14% | +4,350+91.3% | Added |
| B. Metzler seel. Sohn & Co. AG | 9,241 | $1.69M | 0.01% | 00.0% | Unchanged |
| Ieq Capital, LLC | 9,395 | $1.72M | 0.01% | −1,425−13.2% | Reduced |
| Integrity Alliance, LLC. | 9,605 | $1.75M | 0.06% | +9,605 | New |
| Legato Capital Management LLC | 9,627 | $1.76M | 0.15% | +4,576+90.6% | Added |
| Cetera Investment Advisers | 9,706 | $1.77M | 0.00% | +38+0.4% | Added |
| ProShare Advisors LLC | 9,730 | $1.78M | 0.00% | +1,032+11.9% | Added |
| Arizona State Retirement System | 9,787 | $1.79M | 0.01% | −409−4.0% | Reduced |
| Franklin Street Advisors Inc | 10,000 | $1.83M | 0.10% | +10,000 | New |
| Coppell Advisory Solutions LLC | 12,747 | $1.90M | 0.19% | +12,747 | New |
| Penserra Capital Management LLC | 10,450 | $1.91M | 0.02% | +10,450 | New |
| STRS Ohio | 10,800 | $1.97M | 0.01% | −1,100−9.2% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 10,982 | $2.01M | 0.02% | −220−2.0% | Reduced |
| HighVista Strategies LLC | 11,131 | $2.03M | 0.52% | +1,783+19.1% | Added |
| Captrust Financial Advisors | 11,244 | $2.05M | 0.00% | +3,285+41.3% | Added |
| Janney Montgomery Scott LLC | 11,480 | $2.10M | 0.00% | −1,525−11.7% | Reduced |
| Oak Ridge Investments LLC | 11,741 | $2.14M | 0.13% | −324−2.7% | Reduced |
| State of New Jersey Common Pension Fund D | 11,923 | $2.18M | 0.01% | −6,235−34.3% | Reduced |
| Royal Bank of Canada | 12,074 | $2.21M | 0.00% | +1,019+9.2% | Added |
| Sofinnova Investments, Inc. | 12,266 | $2.24M | 0.10% | −381,233−96.9% | Reduced |
| Dimensional Fund Advisors LP | 12,431 | $2.27M | 0.00% | −6,761−35.2% | Reduced |
| Campbell & CO Investment Adviser LLC | 12,459 | $2.28M | 0.11% | +6,382+105.0% | Added |
| Handelsbanken Fonder AB | 12,600 | $2.30M | 0.01% | +1,200+10.5% | Added |
| Comerica Bank | 12,683 | $2.32M | 0.01% | −75−0.6% | Reduced |
| Seven Fleet Capital Management LP | 12,955 | $2.37M | 1.60% | +12,955 | New |
| Guggenheim Capital LLC | 13,030 | $2.38M | 0.02% | +513+4.1% | Added |
| Lazard Asset Management LLC | 13,410 | $2.45M | 0.00% | −8,427−38.6% | Reduced |
| T. Rowe Price Investment Management, Inc. | 13,645 | $2.49M | 0.00% | −260,369−95.0% | Reduced |
| 1832 Asset Management L.P. | 13,700 | $2.50M | 0.00% | +13,700 | New |
| DekaBank Deutsche Girozentrale | 30,000 | $2.58M | 0.00% | 00.0% | Unchanged |
| Intech Investment Management LLC | 14,428 | $2.64M | 0.02% | −1,621−10.1% | Reduced |
| Torray LLC | 14,794 | $2.70M | 0.39% | −2,625−15.1% | Reduced |
| Janus Henderson Group PLC | 15,104 | $2.76M | 0.00% | 00.0% | Unchanged |
| Mariner, LLC | 15,288 | $2.79M | 0.00% | −1,329−8.0% | Reduced |
| Landscape Capital Management, L.L.C. | 15,305 | $2.80M | 0.19% | −3,983−20.7% | Reduced |
| Virtu Financial LLC | 15,573 | $2.84M | 0.11% | +15,573 | New |
| CIBC Private Wealth Group, LLC | 15,684 | $2.86M | 0.00% | +1,309+9.1% | Added |
| Essex Investment Management Co LLC | 17,381 | $3.17M | 0.48% | +17,064+5,383.0% | Added |
| Advisor Group Holdings, Inc. | 17,642 | $3.22M | 0.00% | +11,238+175.5% | Added |
| SG Americas Securities, LLC | 17,681 | $3.23M | 0.00% | +5,584+46.2% | Added |
| Stanley-Laman Group, Ltd. | 17,918 | $3.27M | 0.42% | +417+2.4% | Added |
| Point72 Asset Management, L.P. | 17,999 | $3.29M | 0.01% | −715−3.8% | Reduced |
| 1492 Capital Management LLC | 18,063 | $3.30M | 1.26% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 18,845 | $3.44M | 0.01% | −5,500−22.6% | Reduced |
| HRT Financial LP | 18,862 | $3.44M | 0.01% | +16,581+726.9% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 19,032 | $3.48M | 0.01% | +230+1.2% | Added |
| Quantbot Technologies LP | 19,396 | $3.54M | 0.12% | +8,519+78.3% | Added |
| Knights of Columbus Asset Advisors LLC | 19,806 | $3.62M | 0.21% | −620−3.0% | Reduced |
| Wealth Enhancement Advisory Services, LLC | 21,758 | $3.74M | 0.01% | +253+1.2% | Added |
| Meridian Wealth Management, LLC | 21,724 | $3.97M | 0.14% | −400−1.8% | Reduced |
| Group One Trading, L.P. | 22,211 | $4.06M | 0.12% | −9,492−29.9% | Reduced |
| Pinnacle Financial Partners, Inc. | 22,739 | $4.15M | 0.03% | +22,739 | New |
| Castleark Management LLC | 24,253 | $4.43M | 0.13% | +9,110+60.2% | Added |
| Blackstone Group Inc. | 24,500 | $4.47M | 0.02% | −115,500−82.5% | Reduced |
| Creative Planning | 24,647 | $4.50M | 0.00% | +3,369+15.8% | Added |
| Simplex Trading, LLC | 25,222 | $4.61M | 0.13% | +12,646+100.6% | Added |
| Engineers Gate Manager LP | 26,055 | $4.76M | 0.06% | +13,877+114.0% | Added |
| State of Wisconsin Investment Board | 26,603 | $4.86M | 0.01% | −3,722−12.3% | Reduced |
| Polygon Management Ltd. | 26,934 | $4.92M | 1.04% | −19,522−42.0% | Reduced |
| Bellevue Group AG | 27,600 | $5.04M | 0.10% | −24,735−47.3% | Reduced |
| Susquehanna International Group, LLP | 29,841 | $5.45M | 0.01% | −20,405−40.6% | Reduced |
| LPL Financial LLC | 30,408 | $5.55M | 0.00% | +3,951+14.9% | Added |
| Envestnet Asset Management Inc | 30,491 | $5.57M | 0.00% | −851−2.7% | Reduced |
| XTX Topco Ltd | 31,854 | $5.82M | 0.15% | +30,015+1,632.1% | Added |
| Dana Investment Advisors, Inc. | 33,197 | $6.06M | 0.18% | −415−1.2% | Reduced |
| California State Teachers Retirement System | 33,667 | $6.15M | 0.01% | −648−1.9% | Reduced |
| Millennium Management LLC | 33,937 | $6.20M | 0.00% | +28,196+491.1% | Added |
| HB Wealth Management, LLC | 34,102 | $6.23M | 0.04% | −6,104−15.2% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 34,854 | $6.37M | 0.14% | +7,827+29.0% | Added |
| Occam Crest Management LP | 35,000 | $6.39M | 4.59% | +2,000+6.1% | Added |
| Van Eck Associates Corp | 35,077 | $6.41M | 0.01% | +20,204+135.8% | Added |
| Russell Investments Group, Ltd. | 35,575 | $6.50M | 0.01% | +9,973+39.0% | Added |
| KVP Capital Advisors, LP | 36,200 | $6.61M | 6.83% | +36,200 | New |
| Legal & General Group Plc | 36,702 | $6.70M | 0.00% | −1,083−2.9% | Reduced |
| Superstring Capital Management LP | 37,433 | $6.84M | 3.66% | +37,433 | New |
| Hennion & Walsh Asset Management, Inc. | 38,386 | $7.01M | 0.24% | −8,530−18.2% | Reduced |
| Kennedy Capital Management, Inc. | 39,134 | $7.15M | 0.15% | +360+0.9% | Added |
| Moody Aldrich Partners LLC | 40,273 | $7.36M | 1.37% | −11,203−21.8% | Reduced |
| F/M Investments LLC | 41,132 | $7.51M | 0.29% | +1,637+4.1% | Added |
| TD Asset Management Inc | 41,972 | $7.67M | 0.01% | −2,220−5.0% | Reduced |
| Mutual of America Capital Management LLC | 42,040 | $7.68M | 0.08% | −266−0.6% | Reduced |
| New York State Common Retirement Fund | 42,509 | $7.76M | 0.01% | +9,235+27.8% | Added |
| First Trust Advisors LP | 43,413 | $7.93M | 0.01% | +6,276+16.9% | Added |
| Pallas Capital Advisors LLC | 43,909 | $8.02M | 0.26% | +4,465+11.3% | Added |
| BVF Inc | 45,757 | $8.36M | 0.28% | −441,000−90.6% | Reduced |
| Clearbridge Investments, LLC | 46,326 | $8.46M | 0.01% | −11,341−19.7% | Reduced |
| Peregrine Capital Management LLC | 46,633 | $8.52M | 0.26% | −17,888−27.7% | Reduced |