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Axsome Therapeutics, Inc.

AXSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001579428

In the last 90 days, Axsome Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 505 institutions reported holding it in 13F filings for Q2 2026, worth $9.34B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Axsome Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
355
+10 vs. Q2 2025
Shares held
37.2M
−189.7K (−0.5%) vs. Q2 2025
Total value
$4.51B
+$613.1M (+15.7%) vs. Q2 2025
New holders
49
146 more added
Sold out
39
104 more reduced

3 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AXSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 355 institutions
Q1 2021: 184 institutionsQ2 2021: 176 institutionsQ3 2021: 171 institutionsQ4 2021: 167 institutionsQ1 2022: 175 institutionsQ2 2022: 174 institutionsQ3 2022: 188 institutionsQ4 2022: 219 institutionsQ1 2023: 197 institutionsQ2 2023: 231 institutionsQ3 2023: 227 institutionsQ4 2023: 245 institutionsQ1 2024: 259 institutionsQ2 2024: 257 institutionsQ3 2024: 280 institutionsQ4 2024: 292 institutionsQ1 2025: 353 institutionsQ2 2025: 348 institutionsQ3 2025: 355 institutionsQ4 2025: 399 institutionsQ1 2026: 410 institutionsQ2 2026: 505 institutions
Value heldQ3 2025: $4.51B
Q1 2021: $1.31BQ2 2021: $1.51BQ3 2021: $627.3MQ4 2021: $704.2MQ1 2022: $787.4MQ2 2022: $826.7MQ3 2022: $1.15BQ4 2022: $2.32BQ1 2023: $1.97BQ2 2023: $2.61BQ3 2023: $2.65BQ4 2023: $3.07BQ1 2024: $3.09BQ2 2024: $3.28BQ3 2024: $3.48BQ4 2024: $3.15BQ1 2025: $4.37BQ2 2025: $3.95BQ3 2025: $4.51BQ4 2025: $6.86BQ1 2026: $6.41BQ2 2026: $9.34B
Institutions holding AXSM and their total value by quarter
QuarterHoldersValue
Q2 2026505$9.34B
Q1 2026410$6.41B
Q4 2025399$6.86B
Q3 2025355$4.51B
Q2 2025348$3.95B
Q1 2025353$4.37B
Q4 2024292$3.15B
Q3 2024280$3.48B
Q2 2024257$3.28B
Q1 2024259$3.09B
Q4 2023245$3.07B
Q3 2023227$2.65B
Q2 2023231$2.61B
Q1 2023197$1.97B
Q4 2022219$2.32B
Q3 2022188$1.15B
Q2 2022174$826.7M
Q1 2022175$787.4M
Q4 2021167$704.2M
Q3 2021171$627.3M
Q2 2021176$1.51B
Q1 2021184$1.31B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Axsome Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding AXSM in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Janney Montgomery Scott LLC13,005$1.58M0.00%−18−0.1%Reduced
Wesbanco Bank Inc13,300$1.62M0.04%00.0%Unchanged
CIBC Private Wealth Group, LLC14,375$1.75M0.00%+686+5.0%Added
Van Eck Associates Corp14,873$1.81M0.00%−1,460−8.9%Reduced
Janus Henderson Group PLC15,104$1.83M0.00%+1,104+7.9%Added
Castleark Management LLC15,143$1.84M0.05%−22,897−60.2%Reduced
SummitTX Capital, L.P.15,350$1.86M0.08%+12,641+466.6%Added
Intech Investment Management LLC16,049$1.95M0.02%−6,907−30.1%Reduced
Mariner, LLC16,617$2.02M0.00%+1,023+6.6%Added
Voleon Capital Management LP16,734$2.03M0.05%+16,734New
Torray LLC17,419$2.12M0.29%+354+2.1%Added
Stanley-Laman Group, Ltd.17,501$2.13M0.30%+17,501New
Wolverine Trading, LLC18,157$2.14M0.04%+548+3.1%Added
Readystate Asset Management LP17,860$2.17M0.11%−76,711−81.1%Reduced
1492 Capital Management LLC18,063$2.19M0.89%+6,220+52.5%Added
State of New Jersey Common Pension Fund D18,158$2.21M0.01%+109+0.6%Added
Edgestream Partners, L.P.18,346$2.23M0.07%−51,615−73.8%Reduced
Point72 Asset Management, L.P.18,714$2.27M0.00%−332,259−94.7%Reduced
Mirae Asset Global ETFs Holdings Ltd.18,802$2.28M0.00%−3,381−15.2%Reduced
Dimensional Fund Advisors LP19,192$2.33M0.00%+11,849+161.4%Added
Landscape Capital Management, L.L.C.19,288$2.34M0.15%+13,579+237.9%Added
Knights of Columbus Asset Advisors LLC20,426$2.48M0.14%+514+2.6%Added
Wealth Enhancement Advisory Services, LLC21,505$2.55M0.00%+827+4.0%Added
Cubist Systematic Strategies, LLC21,165$2.57M0.04%−138,068−86.7%Reduced
Creative Planning21,278$2.58M0.00%+5,198+32.3%Added
Lazard Asset Management LLC21,837$2.65M0.00%−7,456−25.5%Reduced
Meridian Wealth Management, LLC22,124$2.69M0.10%+103+0.5%Added
Synovus Financial Corp22,156$2.69M0.03%−170−0.8%Reduced
Ensign Peak Advisors, Inc24,345$2.96M0.00%−6,250−20.4%Reduced
Alps Advisors Inc24,437$2.97M0.02%−2,095−7.9%Reduced
Jump Financial, LLC25,000$3.04M0.04%−103,500−80.5%Reduced
Russell Investments Group, Ltd.25,602$3.11M0.00%+7,798+43.8%Added
LPL Financial LLC26,457$3.21M0.00%+2,211+9.1%Added
Y-Intercept (Hong Kong) Ltd27,027$3.28M0.08%−3,613−11.8%Reduced
DekaBank Deutsche Girozentrale30,000$3.49M0.01%00.0%Unchanged
Capital Fund Management S.A.28,758$3.49M0.03%−32,005−52.7%Reduced
State of Wisconsin Investment Board30,325$3.68M0.01%+4,478+17.3%Added
Envestnet Asset Management Inc31,342$3.81M0.00%+3,205+11.4%Added
Group One Trading, L.P.31,703$3.85M0.12%−4,825−13.2%Reduced
Occam Crest Management LP33,000$4.01M2.72%+33,000New
New York State Common Retirement Fund33,274$4.04M0.01%+875+2.7%Added
Dana Investment Advisors, Inc.33,612$4.08M0.12%+9,539+39.6%Added
SVB Capital Management, LLC33,849$4.11M12.95%00.0%Unchanged
California State Teachers Retirement System34,315$4.17M0.00%+20.0%Added
First Trust Advisors LP37,137$4.51M0.00%−25,023−40.3%Reduced
Legal & General Group Plc37,785$4.59M0.00%−2,460−6.1%Reduced
Kennedy Capital Management, Inc.38,774$4.71M0.10%+10,819+38.7%Added
Pallas Capital Advisors LLC39,444$4.79M0.18%+1,672+4.4%Added
F/M Investments LLC39,495$4.80M0.18%+7,279+22.6%Added
HB Wealth Management, LLC40,206$4.88M0.03%+15,266+61.2%Added
Mutual of America Capital Management LLC42,306$5.14M0.05%−997−2.3%Reduced
Algert Global LLC44,150$5.36M0.09%+6,720+18.0%Added
TD Asset Management Inc44,192$5.37M0.00%+22,914+107.7%Added
Polygon Management Ltd.46,456$5.64M0.82%+4,925+11.9%Added
Hennion & Walsh Asset Management, Inc.46,916$5.70M0.21%−2,984−6.0%Reduced
SEI Investments Co48,127$5.85M0.01%+4,178+9.5%Added
Baldwin Brothers Inc48,570$5.90M0.38%00.0%Unchanged
Nicholas Investment Partners, LP48,657$5.91M0.45%+6,503+15.4%Added
Atika Capital Management LLC49,000$5.95M0.51%+2,879+6.2%Added
Axiom Investors LLC49,253$5.98M0.04%+22,147+81.7%Added
Blair William & Co50,077$6.08M0.02%+595+1.2%Added
Susquehanna International Group, LLP50,246$6.10M0.01%−55,775−52.6%Reduced
Moody Aldrich Partners LLC51,476$6.25M1.19%−9,934−16.2%Reduced
Bellevue Group AG52,335$6.36M0.13%−3,918−7.0%Reduced
Privium Fund Management B.V.52,732$6.40M1.15%00.0%Unchanged
Wells Fargo & Company55,273$6.71M0.00%−430−0.8%Reduced
Royce & Associates LP56,036$6.81M0.07%+30,279+117.6%Added
HighTower Advisors, LLC57,115$6.94M0.01%+46,153+421.0%Added
Federated Hermes, Inc.57,285$6.96M0.01%+816+1.4%Added
Clearbridge Investments, LLC57,667$7.00M0.01%+1,351+2.4%Added
Rhumbline Advisers60,778$7.38M0.01%−1,029−1.7%Reduced
Alliancebernstein L.P.63,065$7.66M0.00%+17,083+37.2%Added
IFP Advisors, Inc63,313$7.69M0.20%−705−1.1%Reduced
Canada Pension Plan Investment Board64,400$7.82M0.01%−7,900−10.9%Reduced
Peregrine Capital Management LLC64,521$7.84M0.24%−8,947−12.2%Reduced
Emerald Mutual Fund Advisers Trust65,505$7.96M0.41%+1,570+2.5%Added
Swiss National Bank66,800$8.11M0.00%+1,600+2.5%Added
Universal- Beteiligungs- und Servicegesellschaft mbH67,902$8.25M0.01%+15,934+30.7%Added
Barclays PLC72,067$8.75M0.00%−25,423−26.1%Reduced
Summit Financial, LLC77,540$9.42M0.14%+77,540New
Iridian Asset Management LLC83,553$10.1M3.99%−8,208−8.9%Reduced
Spears Abacus Advisors LLC84,151$10.2M0.19%00.0%Unchanged
UBS Asset Management Americas Inc86,691$10.5M0.00%−47,410−35.4%Reduced
Granite Investment Partners, LLC88,558$10.8M0.61%−39,968−31.1%Reduced
Neuberger Berman Group LLC91,178$11.1M0.01%+20,546+29.1%Added
Standard Life Aberdeen plc94,648$11.5M0.02%+12,732+15.5%Added
Deutsche Bank AG96,692$11.7M0.00%+3,802+4.1%Added
Cormorant Asset Management, LP100,000$12.1M0.84%00.0%Unchanged
HSBC Holdings PLC101,001$12.3M0.01%+2,883+2.9%Added
DnB Asset Management AS101,981$12.4M0.05%+25,339+33.1%Added
Ameriprise Financial Inc108,236$13.1M0.00%+38,152+54.4%Added
Emerald Advisers, LLC108,942$13.2M0.42%−3,527−3.1%Reduced
Voya Investment Management LLC114,050$13.9M0.01%−25,239−18.1%Reduced
WCM Investment Management, LLC119,696$14.1M0.03%+300.0%Added
AQR Capital Management LLC118,656$14.4M0.01%−9,161−7.2%Reduced
Frontier Capital Management Co LLC126,382$15.3M0.14%+97,540+338.2%Added
Jane Street Group, LLC130,845$15.9M0.02%+130,845New
US Bancorp131,533$16.0M0.02%+686+0.5%Added
Manufacturers Life Insurance Company, The132,717$16.1M0.01%−1,106−0.8%Reduced
Blackstone Group Inc.140,000$17.0M0.07%00.0%Unchanged