Axsome Therapeutics, Inc.
AXSM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001579428
In the last 90 days, Axsome Therapeutics, Inc. insiders filed 0 open-market purchases and 2 sales; 505 institutions reported holding it in 13F filings for Q2 2026, worth $9.34B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Axsome Therapeutics, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 353
- +64 vs. Q4 2024
- Shares held
- 37.5M
- +486.2K (+1.3%) vs. Q4 2024
- Total value
- $4.37B
- +$1.24B (+39.7%) vs. Q4 2024
- New holders
- 92
- 102 more added
- Sold out
- 28
- 115 more reduced
3 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AXSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 505 | $9.34B |
| Q1 2026 | 410 | $6.41B |
| Q4 2025 | 399 | $6.86B |
| Q3 2025 | 355 | $4.51B |
| Q2 2025 | 348 | $3.95B |
| Q1 2025 | 353 | $4.37B |
| Q4 2024 | 292 | $3.15B |
| Q3 2024 | 280 | $3.48B |
| Q2 2024 | 257 | $3.28B |
| Q1 2024 | 259 | $3.09B |
| Q4 2023 | 245 | $3.07B |
| Q3 2023 | 227 | $2.65B |
| Q2 2023 | 231 | $2.61B |
| Q1 2023 | 197 | $1.97B |
| Q4 2022 | 219 | $2.32B |
| Q3 2022 | 188 | $1.15B |
| Q2 2022 | 174 | $826.7M |
| Q1 2022 | 175 | $787.4M |
| Q4 2021 | 167 | $704.2M |
| Q3 2021 | 171 | $627.3M |
| Q2 2021 | 176 | $1.51B |
| Q1 2021 | 184 | $1.31B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Axsome Therapeutics, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Point72 Asset Management, L.P. | 126,193 | $14.7M | 0.04% | −58,945−31.8% | Reduced |
| US Bancorp | 130,295 | $15.2M | 0.02% | −724−0.6% | Reduced |
| Bank of New York Mellon Corp | 131,023 | $15.3M | 0.00% | −3,527−2.6% | Reduced |
| Renaissance Technologies LLC | 134,400 | $15.7M | 0.02% | +134,400 | New |
| Granite Investment Partners, LLC | 138,719 | $16.2M | 0.82% | +47,070+51.4% | Added |
| Squarepoint Ops LLC | 141,597 | $16.5M | 0.04% | +52,167+58.3% | Added |
| Two Sigma Advisers, LP | 149,600 | $17.4M | 0.04% | +143,300+2,274.6% | Added |
| Raymond James Financial Inc | 155,075 | $18.1M | 0.01% | −19,511−11.2% | Reduced |
| Sofinnova Investments, Inc. | 175,317 | $20.4M | 1.54% | −316,409−64.3% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 175,942 | $20.5M | 0.09% | +102,445+139.4% | Added |
| Cubist Systematic Strategies, LLC | 177,814 | $20.7M | 0.27% | +60,877+52.1% | Added |
| MetLife Investment Management | 178,955 | $20.9M | 0.11% | +156,678+703.3% | Added |
| BNP Paribas Arbitrage, SA | 182,632 | $21.3M | 0.02% | −3,029−1.6% | Reduced |
| Driehaus Capital Management LLC | 214,139 | $25.0M | 0.24% | +214,139 | New |
| Franklin Resources Inc | 226,515 | $26.4M | 0.01% | +44,225+24.3% | Added |
| Millennium Management LLC | 235,311 | $27.4M | 0.03% | +231,065+5,441.9% | Added |
| Voloridge Investment Management, LLC | 235,383 | $27.5M | 0.10% | +235,383 | New |
| Cormorant Asset Management, LP | 250,000 | $29.2M | 2.21% | −75,000−23.1% | Reduced |
| T. Rowe Price Investment Management, Inc. | 266,997 | $31.1M | 0.02% | +266,997 | New |
| Qube Research & Technologies Ltd | 282,376 | $32.9M | 0.05% | +126,465+81.1% | Added |
| Loomis Sayles & Co L P | 284,170 | $33.1M | 0.05% | −5,941−2.0% | Reduced |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 285,494 | $33.3M | 6.87% | +251,775+746.7% | Added |
| UBS Group AG | 288,647 | $33.7M | 0.01% | +141,300+95.9% | Added |
| Principal Financial Group Inc | 295,671 | $34.5M | 0.02% | +88,606+42.8% | Added |
| Goldman Sachs Group Inc | 301,718 | $35.2M | 0.01% | +84,151+38.7% | Added |
| Woodline Partners LP | 304,084 | $35.5M | 0.23% | −104,357−25.6% | Reduced |
| Pictet Asset Management Holding SA | 333,205 | $38.9M | 0.04% | +328,527+7,022.8% | Added |
| Charles Schwab Investment Management Inc | 337,246 | $39.3M | 0.01% | +9,212+2.8% | Added |
| Perceptive Advisors LLC | 355,107 | $41.4M | 1.47% | −308,967−46.5% | Reduced |
| 1832 Asset Management L.P. | 363,200 | $42.4M | 0.08% | +363,200 | New |
| OrbiMed Advisors LLC | 386,700 | $45.1M | 1.08% | +386,700 | New |
| Northern Trust Corp | 410,969 | $47.9M | 0.01% | +8,469+2.1% | Added |
| Nuveen, LLC | 413,141 | $48.2M | 0.02% | +413,141 | New |
| Norges Bank | 437,497 | $51.0M | 0.01% | +34,471+8.6% | Added |
| Morgan Stanley | 457,416 | $53.3M | 0.00% | −119,442−20.7% | Reduced |
| Man Group plc | 513,221 | $59.9M | 0.18% | +349,833+214.1% | Added |
| Bank of America Corp | 533,902 | $62.3M | 0.01% | +329,315+161.0% | Added |
| D. E. Shaw & Co., Inc. | 547,665 | $63.9M | 0.08% | +527,319+2,591.8% | Added |
| PFM Health Sciences, LP | 556,545 | $64.9M | 4.98% | +89,118+19.1% | Added |
| Assenagon Asset Management S.A. | 627,418 | $73.2M | 0.13% | +623,717+16,852.7% | Added |
| Alethea Capital Management, LLC | 667,368 | $77.8M | 58.07% | −66,949−9.1% | Reduced |
| Wellington Management Group LLP | 703,279 | $82.0M | 0.02% | +30,122+4.5% | Added |
| Eventide Asset Management, LLC | 744,850 | $86.9M | 1.73% | −83,861−10.1% | Reduced |
| Fairmount Funds Management LLC | 815,176 | $95.1M | 14.75% | −653,807−44.5% | Reduced |
| Invesco Ltd. | 857,001 | $100.0M | 0.02% | +164,537+23.8% | Added |
| State Street Corp | 906,020 | $105.7M | 0.00% | −41,231−4.4% | Reduced |
| Geode Capital Management, LLC | 934,853 | $109.1M | 0.01% | +22,315+2.4% | Added |
| Macquarie Group Ltd | 976,260 | $113.9M | 0.14% | +12,213+1.3% | Added |
| FMR LLC | 1,247,231 | $145.5M | 0.01% | +246,785+24.7% | Added |
| BVF Inc | 1,690,221 | $197.1M | 8.03% | +302,157+21.8% | Added |
| RTW Investments, LP | 2,922,729 | $340.9M | 5.21% | −1,128,636−27.9% | Reduced |
| BlackRock, Inc. | 3,524,411 | $411.1M | 0.01% | −8,983−0.3% | Reduced |
| Vanguard Group Inc | 3,876,942 | $452.2M | 0.01% | −25,537−0.7% | Reduced |
| Ra Capital Management, L.P. | 0 | $0 | 0.00% | −1,000,000−100.0% | Sold out |
| Hood River Capital Management LLC | 0 | $0 | 0.00% | −644,785−100.0% | Sold out |
| Boxer Capital Management, LLC | 0 | $0 | 0.00% | −470,000−100.0% | Sold out |
| Checkpoint Capital L.P. | 0 | $0 | 0.00% | −174,769−100.0% | Sold out |
| Caption Management, LLC | 0 | $0 | 0.00% | −115,686−100.0% | Sold out |
| MPM Oncology Impact Management LP | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| Jefferies Financial Group Inc. | 0 | $0 | 0.00% | −40,700−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −38,748−100.0% | Sold out |
| ADAR1 Capital Management, LLC | 0 | $0 | 0.00% | −19,661−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −14,129−100.0% | Sold out |
| Calamos Advisors LLC | 0 | $0 | 0.00% | −12,808−100.0% | Sold out |
| Hudson Bay Capital Management LP | 0 | $0 | 0.00% | −12,500−100.0% | Sold out |
| 1492 Capital Management LLC | 0 | $0 | 0.00% | −11,385−100.0% | Sold out |
| Bridgefront Capital, LLC | 0 | $0 | 0.00% | −10,555−100.0% | Sold out |
| Petrus Trust Company, LTA | 0 | $0 | 0.00% | −8,764−100.0% | Sold out |
| Superstring Capital Management LP | 0 | $0 | 0.00% | −4,268−100.0% | Sold out |
| Sherbrooke Park Advisers LLC | 0 | $0 | 0.00% | −4,082−100.0% | Sold out |
| Seven Springs Wealth Group, LLC | 0 | $0 | 0.00% | −4,005−100.0% | Sold out |
| Virtus ETF Advisers LLC | 0 | $0 | 0.00% | −3,705−100.0% | Sold out |
| 111 Capital | 0 | $0 | 0.00% | −3,291−100.0% | Sold out |
| Flower City Capital | 0 | $0 | 0.00% | −3,000−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −2,942−100.0% | Sold out |
| CI Private Wealth, LLC | 0 | $0 | 0.00% | −2,829−100.0% | Sold out |
| Nomura Holdings Inc | 0 | $0 | 0.00% | −2,500−100.0% | Sold out |
| R Squared Ltd | 0 | $0 | 0.00% | −760−100.0% | Sold out |
| Natixis | 0 | $0 | 0.00% | −748−100.0% | Sold out |
| Aster Capital Management (DIFC) Ltd | 0 | $0 | 0.00% | −128−100.0% | Sold out |
| National Bank of Canada | 0 | $0 | 0.00% | −31−100.0% | Sold out |
| Nuveen Asset Management, LLC | – | – | – | – | Not filed |
| Global Retirement Partners, LLC | – | – | – | – | Not filed |
| Cassady Schiller Wealth Management, LLC | – | – | – | – | Not filed |