Annexon, Inc.
ANNX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001528115
In the last 90 days, Annexon, Inc. insiders filed 1 open-market purchase and 0 sales; 216 institutions reported holding it in 13F filings for Q2 2026, worth $1.02B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Annexon, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 168
- +27 vs. Q3 2025
- Shares held
- 136.9M
- +35.9M (+35.5%) vs. Q3 2025
- Total value
- $687.2M
- +$379.0M (+123.0%) vs. Q3 2025
- New holders
- 41
- 72 more added
- Sold out
- 14
- 30 more reduced
3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ANNX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 216 | $1.02B |
| Q1 2026 | 217 | $863.7M |
| Q4 2025 | 168 | $687.2M |
| Q3 2025 | 144 | $309.2M |
| Q2 2025 | 129 | $238.7M |
| Q1 2025 | 148 | $192.1M |
| Q4 2024 | 153 | $574.6M |
| Q3 2024 | 142 | $651.8M |
| Q2 2024 | 140 | $526.9M |
| Q1 2024 | 127 | $679.4M |
| Q4 2023 | 99 | $365.7M |
| Q3 2023 | 93 | $126.0M |
| Q2 2023 | 95 | $190.0M |
| Q1 2023 | 100 | $207.6M |
| Q4 2022 | 84 | $243.3M |
| Q3 2022 | 72 | $292.3M |
| Q2 2022 | 78 | $144.9M |
| Q1 2022 | 100 | $105.9M |
| Q4 2021 | 97 | $445.7M |
| Q3 2021 | 82 | $708.6M |
| Q2 2021 | 74 | $873.7M |
| Q1 2021 | 72 | $1.04B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Annexon, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Comerica Bank | 32,357 | $162.4K | 0.00% | 00.0% | Unchanged |
| Captrust Financial Advisors | 31,585 | $158.6K | 0.00% | +31,585 | New |
| Mariner, LLC | 31,335 | $157.4K | 0.00% | +31,335 | New |
| CWM, LLC | 30,297 | $152.0K | 0.00% | +6,809+29.0% | Added |
| New York State Common Retirement Fund | 29,568 | $148.4K | 0.00% | −4,911−14.2% | Reduced |
| Axq Capital, LP | 29,108 | $146.1K | 0.03% | +1,241+4.5% | Added |
| Police & Firemen's Retirement System of New Jersey | 28,105 | $141.1K | 0.00% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 28,071 | $141.0K | 0.00% | +17,074+155.3% | Added |
| HSBC Holdings PLC | 25,651 | $130.2K | 0.00% | −70−0.3% | Reduced |
| Raymond James Financial Inc | 24,869 | $124.8K | 0.00% | +4,869+24.3% | Added |
| ProShare Advisors LLC | 24,698 | $124.0K | 0.00% | +4,410+21.7% | Added |
| Creative Planning | 24,004 | $120.5K | 0.00% | +8,553+55.4% | Added |
| Citigroup Inc | 23,640 | $118.7K | 0.00% | +16,812+246.2% | Added |
| Lido Advisors, LLC | 34,952 | $106.6K | 0.00% | 00.0% | Unchanged |
| Wealth Enhancement Advisory Services, LLC | 19,553 | $99.7K | 0.00% | +2,348+13.6% | Added |
| CI Private Wealth, LLC | 19,693 | $98.9K | 0.00% | +28+0.1% | Added |
| Voya Investment Management LLC | 19,318 | $97.0K | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 19,197 | $96.4K | 0.02% | +19,197 | New |
| Canada Pension Plan Investment Board | 17,600 | $88.4K | 0.00% | +17,600 | New |
| Scientech Research LLC | 17,216 | $86.4K | 0.05% | +17,216 | New |
| Coastal Bridge Advisors, LLC | 17,000 | $85.3K | 0.01% | 00.0% | Unchanged |
| VisionPoint Advisory Group, LLC | 15,000 | $75.3K | 0.01% | 00.0% | Unchanged |
| Cerity Partners LLC | 14,801 | $74.3K | 0.00% | +14,801 | New |
| Victory Capital Management Inc | 14,757 | $74.1K | 0.00% | +3,736+33.9% | Added |
| Group One Trading, L.P. | 14,184 | $71.2K | 0.00% | −21,381−60.1% | Reduced |
| Forefront Analytics, LLC | 13,226 | $66.4K | 0.06% | −13,801−51.1% | Reduced |
| JustInvest LLC | 12,901 | $64.8K | 0.00% | −343−2.6% | Reduced |
| Prelude Capital Management, LLC | 12,000 | $60.2K | 0.00% | +12,000 | New |
| Cygnus Capital Advisors, LLC | 12,000 | $60.0K | 0.04% | +12,000 | New |
| Cambridge Investment Research Advisors, Inc. | 10,700 | $54.0K | 0.00% | 00.0% | Unchanged |
| Mount Vernon Associates Inc | 10,500 | $53.0K | 0.04% | +10,500 | New |
| Mercer Global Advisors Inc | 10,386 | $52.1K | 0.00% | +10,386 | New |
| Simplex Trading, LLC | 10,268 | $51.5K | 0.00% | +10,268 | New |
| Landscape Capital Management, L.L.C. | 10,016 | $50.3K | 0.00% | +10,016 | New |
| Harbor Advisors LLC | 10,000 | $50.2K | 0.01% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 9,689 | $48.6K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 9,307 | $46.7K | 0.00% | +831+9.8% | Added |
| Mirae Asset Global Investments Co., Ltd. | 7,033 | $35.3K | 0.00% | +2,785+65.6% | Added |
| California State Teachers Retirement System | 6,163 | $30.9K | 0.00% | +168+2.8% | Added |
| Geneos Wealth Management Inc. | 6,000 | $30.1K | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 5,967 | $30.0K | 0.00% | −640−9.7% | Reduced |
| Amalgamated Bank | 3,144 | $16.0K | 0.00% | −226−6.7% | Reduced |
| Royal Bank of Canada | 2,855 | $15.0K | 0.00% | −282,993−99.0% | Reduced |
| Jones Financial Companies LLLP | 2,987 | $15.0K | 0.00% | +2,987 | New |
| GF Fund Management Co. Ltd. | 2,843 | $14.3K | 0.00% | +479+20.3% | Added |
| Nisa Investment Advisors, LLC | 2,613 | $13.1K | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 2,000 | $10.0K | 0.00% | +2,000 | New |
| Tower Research Capital LLC (TRC) | 1,966 | $9.87K | 0.00% | −4,130−67.7% | Reduced |
| The PNC Financial Services Group, Inc. | 1,132 | $5.68K | 0.00% | +9+0.8% | Added |
| Essential Partners LLC | 1,087 | $5.46K | 0.00% | +794+271.0% | Added |
| Federated Hermes, Inc. | 753 | $3.78K | 0.00% | +753 | New |
| IFP Advisors, Inc | 547 | $2.75K | 0.00% | +197+56.3% | Added |
| EverSource Wealth Advisors, LLC | 539 | $2.71K | 0.00% | +243+82.1% | Added |
| Optiver Holding B.V. | 530 | $2.66K | 0.00% | −774−59.4% | Reduced |
| Allworth Financial LP | 416 | $2.09K | 0.00% | +264+173.7% | Added |
| Daiwa Securities Group Inc. | 352 | $2.00K | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 334 | $1.68K | 0.00% | +334 | New |
| Assetmark, Inc | 333 | $1.67K | 0.00% | +333 | New |
| Farther Finance Advisors, LLC | 309 | $1.55K | 0.00% | +308+30,800.0% | Added |
| HighMark Wealth Management LLC | 300 | $1.51K | 0.00% | 00.0% | Unchanged |
| UMA Financial Services, Inc. | 269 | $1.35K | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 236 | $1.19K | 0.00% | +71+43.0% | Added |
| True Wealth Design, LLC | 211 | $1.06K | 0.00% | +156+283.6% | Added |
| Sunbelt Securities, Inc. | 110 | $552 | 0.00% | +23+26.4% | Added |
| MAI Capital Management | 63 | $317 | 0.00% | +63 | New |
| SBI Securities Co., Ltd. | 25 | $126 | 0.00% | −1−3.8% | Reduced |
| SRS Capital Advisors, Inc. | 19 | $95 | 0.00% | −6,511−99.7% | Reduced |
| Northwestern Mutual Wealth Management Co | 4 | $20 | 0.00% | +4 | New |
| Candriam Luxembourg S.C.A. | 0 | $0 | 0.00% | −2,534,230−100.0% | Sold out |
| Rhenman & Partners Asset Management AB | 0 | $0 | 0.00% | −823,000−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −243,755−100.0% | Sold out |
| Park Avenue Securities LLC | 0 | $0 | 0.00% | −113,068−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −84,582−100.0% | Sold out |
| Alps Advisors Inc | 0 | $0 | 0.00% | −47,879−100.0% | Sold out |
| Atom Investors LP | 0 | $0 | 0.00% | −30,453−100.0% | Sold out |
| Forefront Wealth Partners, LLC | 0 | $0 | 0.00% | −27,027−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −23,800−100.0% | Sold out |
| Matauro, LLC | 0 | $0 | 0.00% | −20,572−100.0% | Sold out |
| 49 Wealth Management, LLC | 0 | $0 | 0.00% | −12,083−100.0% | Sold out |
| Prudential Financial Inc | 0 | $0 | 0.00% | −11,670−100.0% | Sold out |
| Clearstead Advisors, LLC | 0 | $0 | 0.00% | −355−100.0% | Sold out |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −23−100.0% | Sold out |
| Point72 Europe (London) LLP | – | – | – | – | Not filed |
| Cubist Systematic Strategies, LLC | – | – | – | – | Not filed |
| CIBC Bancorp USA Inc. | – | – | – | – | Not filed |