Annexon, Inc.
ANNX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001528115
In the last 90 days, Annexon, Inc. insiders filed 1 open-market purchase and 0 sales; 216 institutions reported holding it in 13F filings for Q2 2026, worth $1.02B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Annexon, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 217
- +51 vs. Q4 2025
- Shares held
- 155.9M
- +26.8M (+20.8%) vs. Q4 2025
- Total value
- $863.7M
- +$215.6M (+33.3%) vs. Q4 2025
- New holders
- 66
- 87 more added
- Sold out
- 15
- 49 more reduced
2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ANNX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 216 | $1.02B |
| Q1 2026 | 217 | $863.7M |
| Q4 2025 | 168 | $687.2M |
| Q3 2025 | 144 | $309.2M |
| Q2 2025 | 129 | $238.7M |
| Q1 2025 | 148 | $192.1M |
| Q4 2024 | 153 | $574.6M |
| Q3 2024 | 142 | $651.8M |
| Q2 2024 | 140 | $526.9M |
| Q1 2024 | 127 | $679.4M |
| Q4 2023 | 99 | $365.7M |
| Q3 2023 | 93 | $126.0M |
| Q2 2023 | 95 | $190.0M |
| Q1 2023 | 100 | $207.6M |
| Q4 2022 | 84 | $243.3M |
| Q3 2022 | 72 | $292.3M |
| Q2 2022 | 78 | $144.9M |
| Q1 2022 | 100 | $105.9M |
| Q4 2021 | 97 | $445.7M |
| Q3 2021 | 82 | $708.6M |
| Q2 2021 | 74 | $873.7M |
| Q1 2021 | 72 | $1.04B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Annexon, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Redmile Group, LLC | 14,549,768 | $80.6M | 5.34% | +4,499,124+44.8% | Added |
| BlackRock, Inc. | 10,938,509 | $60.6M | 0.00% | +1,978,075+22.1% | Added |
| FMR LLC | 10,635,648 | $58.9M | 0.00% | +413,178+4.0% | Added |
| BVF Inc | 8,698,173 | $48.2M | 1.54% | −429,907−4.7% | Reduced |
| State Street Corp | 6,919,255 | $38.3M | 0.00% | +2,267,070+48.7% | Added |
| Vanguard Capital Management LLC | 5,956,589 | $33.0M | 0.00% | +5,956,589 | New |
| Bain Capital Life Sciences Investors, LLC | 5,212,674 | $28.9M | 2.60% | −36,395−0.7% | Reduced |
| Bellevue Group AG | 5,157,290 | $28.6M | 0.68% | 00.0% | Unchanged |
| Mak Capital One LLC | 4,724,043 | $26.2M | 4.33% | +1,765,516+59.7% | Added |
| Adage Capital Partners GP, L.L.C. | 4,300,000 | $23.8M | 0.04% | −1,200,000−21.8% | Reduced |
| Bank of America Corp | 4,259,995 | $23.6M | 0.00% | +2,654,414+165.3% | Added |
| Nuveen, LLC | 4,246,330 | $23.5M | 0.01% | +1,331,006+45.7% | Added |
| Siren, L.L.C. | 3,958,646 | $21.9M | 0.61% | +3,958,646 | New |
| Balyasny Asset Management LLC | 3,886,909 | $21.5M | 0.04% | +587,653+17.8% | Added |
| Ameriprise Financial Inc | 3,449,121 | $19.1M | 0.00% | −899,661−20.7% | Reduced |
| Geode Capital Management, LLC | 3,377,823 | $18.7M | 0.00% | +474,927+16.4% | Added |
| Qube Research & Technologies Ltd | 3,114,314 | $17.3M | 0.02% | +732,835+30.8% | Added |
| Palo Alto Investors LP | 2,948,090 | $16.3M | 2.50% | +563,898+23.7% | Added |
| Morgan Stanley | 2,735,970 | $15.2M | 0.00% | −120,173−4.2% | Reduced |
| Great Point Partners LLC | 2,500,000 | $13.8M | 3.39% | +2,500,000 | New |
| Woodline Partners LP | 2,337,137 | $12.9M | 0.05% | −1,662,937−41.6% | Reduced |
| Opaleye Management Inc. | 2,331,761 | $12.9M | 1.70% | −268,239−10.3% | Reduced |
| Goldman Sachs Group Inc | 2,152,880 | $11.9M | 0.00% | +384,135+21.7% | Added |
| Point72 Asset Management, L.P. | 1,871,795 | $10.4M | 0.02% | +1,500,605+404.3% | Added |
| Vanguard Portfolio Management LLC | 1,483,090 | $8.22M | 0.00% | +1,483,090 | New |
| Y-Intercept (Hong Kong) Ltd | 1,319,913 | $7.31M | 0.14% | +1,319,913 | New |
| Polygon Management Ltd. | 1,292,455 | $7.16M | 1.41% | −740,000−36.4% | Reduced |
| UBS Group AG | 1,245,941 | $6.90M | 0.00% | +868,837+230.4% | Added |
| Millennium Management LLC | 1,238,678 | $6.86M | 0.01% | −1,598,179−56.3% | Reduced |
| Charles Schwab Investment Management Inc | 1,102,445 | $6.11M | 0.00% | +45,385+4.3% | Added |
| Northern Trust Corp | 1,086,902 | $6.02M | 0.00% | +294,902+37.2% | Added |
| Dimensional Fund Advisors LP | 924,078 | $5.12M | 0.00% | +205,398+28.6% | Added |
| Kennedy Capital Management, Inc. | 912,323 | $5.05M | 0.11% | +272,421+42.6% | Added |
| Massachusetts Financial Services Co | 903,368 | $5.00M | 0.00% | −710.0% | Reduced |
| Vanguard Fiduciary Trust Co | 888,552 | $4.92M | 0.00% | +888,552 | New |
| Marshall Wace, LLP | 861,475 | $4.77M | 0.01% | +340,477+65.4% | Added |
| AQR Capital Management LLC | 777,253 | $4.31M | 0.00% | +946+0.1% | Added |
| Invesco Ltd. | 763,005 | $4.23M | 0.00% | −209,444−21.5% | Reduced |
| Acadian Asset Management LLC | 758,232 | $4.20M | 0.01% | −103,013−12.0% | Reduced |
| Russell Investments Group, Ltd. | 711,380 | $3.94M | 0.00% | +28,364+4.2% | Added |
| D. E. Shaw & Co., Inc. | 702,799 | $3.89M | 0.00% | −343,422−32.8% | Reduced |
| Wells Fargo & Company | 698,739 | $3.87M | 0.00% | +124,991+21.8% | Added |
| Parkman Healthcare Partners LLC | 674,013 | $3.73M | 0.39% | +72,811+12.1% | Added |
| Ensign Peak Advisors, Inc | 625,097 | $3.46M | 0.01% | +625,097 | New |
| Longaeva Partners L.P. | 620,401 | $3.44M | 0.17% | −2,479,599−80.0% | Reduced |
| Citadel Advisors LLC | 600,135 | $3.32M | 0.00% | +324,841+118.0% | Added |
| Deerfield Management Company, L.P. (Series C) | 583,913 | $3.23M | 0.04% | 00.0% | Unchanged |
| Ikarian Capital, LLC | 580,244 | $3.21M | 0.46% | +350,000+152.0% | Added |
| Sirios Capital Management L P | 575,063 | $3.19M | 0.39% | −135,193−19.0% | Reduced |
| Deutsche Bank AG | 562,181 | $3.11M | 0.00% | +1,437+0.3% | Added |
| Renaissance Technologies LLC | 544,300 | $3.02M | 0.00% | −258,300−32.2% | Reduced |
| Wellington Management Group LLP | 521,379 | $2.89M | 0.00% | +123,302+31.0% | Added |
| Hennion & Walsh Asset Management, Inc. | 509,689 | $2.82M | 0.10% | −25,297−4.7% | Reduced |
| Silverarc Capital Management, LLC | 496,461 | $2.75M | 0.32% | +496,461 | New |
| Board of Trustees of The Leland Stanford Junior University | 482,550 | $2.67M | 0.31% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 471,391 | $2.61M | 0.00% | +139,353+42.0% | Added |
| Voloridge Investment Management, LLC | 462,068 | $2.56M | 0.01% | +462,068 | New |
| Price T Rowe Associates Inc | 428,720 | $2.38M | 0.00% | −16,354−3.7% | Reduced |
| Mutual of America Capital Management LLC | 416,698 | $2.31M | 0.03% | −225,340−35.1% | Reduced |
| Trexquant Investment LP | 403,657 | $2.24M | 0.02% | +403,657 | New |
| Bank of New York Mellon Corp | 395,019 | $2.19M | 0.00% | +33,342+9.2% | Added |
| Susquehanna Portfolio Strategies, LLC | 360,319 | $2.00M | 0.03% | +3,700+1.0% | Added |
| JPMorgan Chase & Co | 323,894 | $1.61M | 0.00% | +270,165+502.8% | Added |
| Cinctive Capital Management LP | 268,640 | $1.49M | 0.10% | −90,346−25.2% | Reduced |
| BNP Paribas Arbitrage, SA | 255,371 | $1.41M | 0.00% | +193,799+314.8% | Added |
| Swiss National Bank | 236,000 | $1.31M | 0.00% | +236,000 | New |
| Rafferty Asset Management, LLC | 203,269 | $1.13M | 0.00% | +61,625+43.5% | Added |
| SEI Investments Co | 203,236 | $1.13M | 0.00% | +144,977+248.8% | Added |
| Rosalind Advisors, Inc. | 200,000 | $1.11M | 0.45% | +200,000 | New |
| Ieq Capital, LLC | 195,764 | $1.08M | 0.01% | +12,782+7.0% | Added |
| Ishara Investments LP | 174,250 | $965.3K | 0.97% | −575,750−76.8% | Reduced |
| Engineers Gate Manager LP | 174,141 | $964.7K | 0.01% | +174,141 | New |
| J. Goldman & Co LP | 170,817 | $946.3K | 0.04% | −822,978−82.8% | Reduced |
| Boothbay Fund Management, LLC | 166,164 | $920.5K | 0.02% | +102,095+159.4% | Added |
| Rhumbline Advisers | 159,670 | $884.6K | 0.00% | +33,207+26.3% | Added |
| Susquehanna International Group, LLP | 158,640 | $878.9K | 0.00% | −26,868−14.5% | Reduced |
| Algert Global LLC | 154,840 | $857.8K | 0.01% | +154,840 | New |
| Jacobs Levy Equity Management, Inc | 148,941 | $825.1K | 0.00% | −534,938−78.2% | Reduced |
| Manufacturers Life Insurance Company, The | 134,786 | $746.7K | 0.00% | +4,684+3.6% | Added |
| Diadema Partners LP | 132,916 | $736.4K | 0.30% | −217,084−62.0% | Reduced |
| UBS Asset Management Americas Inc | 130,647 | $723.8K | 0.00% | +130,647 | New |
| Schonfeld Strategic Advisors LLC | 123,282 | $683.0K | 0.01% | −399,564−76.4% | Reduced |
| DAFNA Capital Management LLC | 117,812 | $652.7K | 0.15% | −155,000−56.8% | Reduced |
| Victory Capital Management Inc | 115,527 | $640.0K | 0.00% | +100,770+682.9% | Added |
| Man Group plc | 109,222 | $605.1K | 0.00% | +109,222 | New |
| Alliancebernstein L.P. | 119,050 | $597.6K | 0.00% | −21,690−15.4% | Reduced |
| SCS Capital Management LLC | 99,000 | $548.5K | 0.01% | +99,000 | New |
| Bridgeway Capital Management, LLC | 97,800 | $541.8K | 0.01% | −40,000−29.0% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 92,707 | $513.6K | 0.00% | +92,707 | New |
| Profund Advisors LLC | 90,959 | $503.9K | 0.02% | +37,951+71.6% | Added |
| J. Safra Sarasin Holding AG | 90,487 | $501.3K | 0.01% | −27,281−23.2% | Reduced |
| DnB Asset Management AS | 88,617 | $490.9K | 0.00% | −29,707−25.1% | Reduced |
| XTX Topco Ltd | 80,495 | $445.9K | 0.01% | −162,818−66.9% | Reduced |
| Legal & General Group Plc | 80,046 | $443.5K | 0.00% | +70,739+760.1% | Added |
| Vanguard Asset Management, Ltd | 79,486 | $440.4K | 0.00% | +79,486 | New |
| Captrust Financial Advisors | 79,173 | $438.6K | 0.00% | +47,588+150.7% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 76,257 | $414.1K | 0.00% | +21,494+39.2% | Added |
| MetLife Investment Management | 72,444 | $401.3K | 0.00% | +33,385+85.5% | Added |
| Polen Capital Management LLC | 70,152 | $388.6K | 0.00% | +70,152 | New |
| Squarepoint Ops LLC | 67,956 | $376.5K | 0.00% | +67,956 | New |