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Annexon, Inc.

ANNX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001528115

In the last 90 days, Annexon, Inc. insiders filed 1 open-market purchase and 0 sales; 216 institutions reported holding it in 13F filings for Q2 2026, worth $1.02B in total; no superinvestor holds it.

Q1 2026 vs. Q4 2025

How the institutions holding Annexon, Inc. changed between Q4 2025 and Q1 2026.

All holders in Q1 2026All holders in Q4 2025

13F holders of ANNX: Q4 2025 compared with Q1 2026
MeasureQ4 2025Of which not filed for Q1 2026Q1 2026Change
Holders1682217+51
Shares136.9M7.79M155.9M+26.8M (+20.8%)
Value$687.2M$39.1M$863.7M+$215.6M (+33.3%)

2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so the changes leave them out.

New holders (66)

Institutions that held Annexon, Inc. at the end of Q1 2026 but not at the end of Q4 2025.

Institutions new to ANNX in Q1 2026
InstitutionSharesValue% of portfolio
Vanguard Capital Management LLC5,956,589$33.0M0.00%
Siren, L.L.C.3,958,646$21.9M0.61%
Great Point Partners LLC2,500,000$13.8M3.39%
Vanguard Portfolio Management LLC1,483,090$8.22M0.00%
Y-Intercept (Hong Kong) Ltd1,319,913$7.31M0.14%
Vanguard Fiduciary Trust Co888,552$4.92M0.00%
Ensign Peak Advisors, Inc625,097$3.46M0.01%
Silverarc Capital Management, LLC496,461$2.75M0.32%
Voloridge Investment Management, LLC462,068$2.56M0.01%
Trexquant Investment LP403,657$2.24M0.02%
Swiss National Bank236,000$1.31M0.00%
Rosalind Advisors, Inc.200,000$1.11M0.45%
Engineers Gate Manager LP174,141$964.7K0.01%
Algert Global LLC154,840$857.8K0.01%
UBS Asset Management Americas Inc130,647$723.8K0.00%
Man Group plc109,222$605.1K0.00%
SCS Capital Management LLC99,000$548.5K0.01%
Connor, Clark & Lunn Investment Management Ltd.92,707$513.6K0.00%
Vanguard Asset Management, Ltd79,486$440.4K0.00%
Polen Capital Management LLC70,152$388.6K0.00%
Squarepoint Ops LLC67,956$376.5K0.00%
Los Angeles Capital Management LLC62,073$343.9K0.00%
Janus Henderson Group PLC59,100$327.7K0.00%
STRS Ohio55,500$307.5K0.00%
DRW Securities, LLC54,484$301.8K0.02%
Vanguard Global Advisers, LLC54,054$299.5K0.00%
Zurcher Kantonalbank (Zurich Cantonalbank)53,867$298.4K0.00%
Verdad Advisers, LP53,277$295.2K0.33%
BIT Capital GmbH50,000$277.0K0.02%
State of Wisconsin Investment Board49,746$275.6K0.00%
State of New Jersey Common Pension Fund D40,753$225.8K0.00%
Fifth Third Bancorp35,398$196.1K0.00%
Vanguard Investments Australia, Ltd.35,034$194.1K0.00%
Arizona State Retirement System32,753$181.5K0.00%
Gsa Capital Partners LLP31,694$176.0K0.01%
Mirabella Financial Services LLP28,739$159.2K0.02%
Virtu Financial LLC28,450$158.0K0.01%
KLP Kapitalforvaltning AS26,300$145.7K0.00%
E Fund Management Co., Ltd.25,552$141.6K0.00%
AlphaCentric Advisors LLC24,518$135.8K0.14%
Great West Life Assurance Co21,646$121.0K0.00%
Prudential Financial Inc20,180$111.8K0.00%
Pictet Asset Management Holding SA16,701$92.5K0.00%
Fox Run Management, L.L.C.17,678$87.7K0.02%
Teacher Retirement System of Texas15,099$83.6K0.00%
ExodusPoint Capital Management, LP14,938$82.8K0.00%
Vontobel Holding Ltd.14,511$80.4K0.00%
Magnetar Financial LLC14,205$78.7K0.00%
LPL Financial LLC13,214$73.2K0.00%
nVerses Capital, LLC11,897$65.9K0.06%
Xponance, Inc.11,206$62.1K0.00%
Abel Hall, LLC10,921$60.5K0.01%
Merit Financial Group, LLC10,745$59.5K0.00%
Integrated Wealth Concepts LLC10,232$56.7K0.00%
Shay Capital LLC10,000$55.4K0.01%
BNP PARIBAS ASSET MANAGEMENT Holding S.A.2,367$13.1K0.00%
Trask Adam Roland1,000$5.54K0.01%
GAMMA Investing LLC316$1.75K0.00%
Quantbot Technologies LP308$1.71K0.00%
Root Financial Partners, LLC94$5210.00%
Fortitude Family Office, LLC87$4820.00%
US Bancorp77$4270.00%
Advisory Services Network, LLC23$1270.00%
Stone House Investment Management, LLC20$1110.00%
SJS Investment Consulting Inc.17$950.00%
JPL Wealth Management, LLC13$730.00%

Sold out (15)

Institutions that held Annexon, Inc. at the end of Q4 2025 and filed for Q1 2026 without it.

Institutions that sold out of ANNX in Q1 2026
InstitutionShares, Q4 2025Value, Q4 2025
Sphera Funds Management Ltd.1,316,212$6.61M
SummitTX Capital, L.P.438,497$2.20M
Jump Financial, LLC122,858$616.7K
Caption Management, LLC119,491$599.8K
Citizens Financial Group Inc40,000$200.8K
Pale Fire Capital SE38,600$193.8K
Landing Point Financial Group, LLC34,900$175.2K
SG Americas Securities, LLC28,071$141.0K
HSBC Holdings PLC25,651$130.2K
Group One Trading, L.P.14,184$71.2K
Simplex Trading, LLC10,268$51.5K
Amalgamated Bank3,144$16.0K
Daiwa Securities Group Inc.352$2.00K
Assetmark, Inc333$1.67K
Northwestern Mutual Wealth Management Co4$20

Not filed for Q1 2026 yet (2)

Institutions that held Annexon, Inc. at the end of Q4 2025 and haven't filed a 13F for Q1 2026. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding ANNX in Q4 2025 that haven't filed for Q1 2026
InstitutionShares, Q4 2025Value, Q4 2025
Vanguard Group Inc7,753,387$38.9M
Comerica Bank32,357$162.4K