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Annexon, Inc.

ANNX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001528115

In the last 90 days, Annexon, Inc. insiders filed 1 open-market purchase and 0 sales; 216 institutions reported holding it in 13F filings for Q2 2026, worth $1.02B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Annexon, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
153
+12 vs. Q3 2024
Shares held
112.2M
+2.57M (+2.3%) vs. Q3 2024
Total value
$574.6M
−$73.3M (−11.3%) vs. Q3 2024
New holders
30
60 more added
Sold out
18
38 more reduced

1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANNX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 153 institutions
Q1 2021: 72 institutionsQ2 2021: 74 institutionsQ3 2021: 82 institutionsQ4 2021: 97 institutionsQ1 2022: 100 institutionsQ2 2022: 78 institutionsQ3 2022: 72 institutionsQ4 2022: 84 institutionsQ1 2023: 100 institutionsQ2 2023: 95 institutionsQ3 2023: 93 institutionsQ4 2023: 99 institutionsQ1 2024: 127 institutionsQ2 2024: 140 institutionsQ3 2024: 142 institutionsQ4 2024: 153 institutionsQ1 2025: 148 institutionsQ2 2025: 129 institutionsQ3 2025: 144 institutionsQ4 2025: 168 institutionsQ1 2026: 217 institutionsQ2 2026: 216 institutions
Value heldQ4 2024: $574.6M
Q1 2021: $1.04BQ2 2021: $873.7MQ3 2021: $708.6MQ4 2021: $445.7MQ1 2022: $105.9MQ2 2022: $144.9MQ3 2022: $292.3MQ4 2022: $243.3MQ1 2023: $207.6MQ2 2023: $190.0MQ3 2023: $126.0MQ4 2023: $365.7MQ1 2024: $679.4MQ2 2024: $526.9MQ3 2024: $651.8MQ4 2024: $574.6MQ1 2025: $192.1MQ2 2025: $238.7MQ3 2025: $309.2MQ4 2025: $687.2MQ1 2026: $863.7MQ2 2026: $1.02B
Institutions holding ANNX and their total value by quarter
QuarterHoldersValue
Q2 2026216$1.02B
Q1 2026217$863.7M
Q4 2025168$687.2M
Q3 2025144$309.2M
Q2 2025129$238.7M
Q1 2025148$192.1M
Q4 2024153$574.6M
Q3 2024142$651.8M
Q2 2024140$526.9M
Q1 2024127$679.4M
Q4 202399$365.7M
Q3 202393$126.0M
Q2 202395$190.0M
Q1 2023100$207.6M
Q4 202284$243.3M
Q3 202272$292.3M
Q2 202278$144.9M
Q1 2022100$105.9M
Q4 202197$445.7M
Q3 202182$708.6M
Q2 202174$873.7M
Q1 202172$1.04B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Annexon, Inc.; share changes are against Q3 2024.

Institutions holding ANNX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC14,224,383$73.0M0.00%+5,662,434+66.1%Added
BlackRock, Inc.8,486,187$43.5M0.00%+838,473+11.0%Added
Satter Management Co., L.P.7,406,024$38.0M66.89%00.0%Unchanged
BVF Inc7,000,000$35.9M1.22%00.0%Unchanged
Redmile Group, LLC6,300,644$32.3M2.25%−126,818−2.0%Reduced
Point72 Asset Management, L.P.5,626,796$28.9M0.08%+299,798+5.6%Added
Vanguard Group Inc5,546,918$28.5M0.00%+576,625+11.6%Added
Bain Capital Life Sciences Investors, LLC5,249,069$26.9M3.17%−3,200,679−37.9%Reduced
Bellevue Group AG5,157,290$26.5M0.51%00.0%Unchanged
State Street Corp4,510,714$23.1M0.00%+668,835+17.4%Added
Nuveen Asset Management, LLC2,720,485$14.0M0.00%+164,915+6.5%Added
Woodline Partners LP2,690,787$13.8M0.09%−739,373−21.6%Reduced
Logos Global Management LP2,550,000$13.1M1.53%−50,000−1.9%Reduced
Candriam Luxembourg S.C.A.2,534,230$13.0M0.07%+341,431+15.6%Added
Sio Capital Management, LLC2,367,007$12.1M3.42%+933,852+65.2%Added
Geode Capital Management, LLC2,171,478$11.1M0.00%+27,843+1.3%Added
JPMorgan Chase & Co1,511,517$7.75M0.00%−194,665−11.4%Reduced
Polygon Management Ltd.1,400,000$7.18M2.32%+615,645+78.5%Added
Dimensional Fund Advisors LP1,360,076$6.98M0.00%+231,034+20.5%Added
Goldman Sachs Group Inc1,317,011$6.76M0.00%−587,367−30.8%Reduced
Sphera Funds Management Ltd.1,243,039$6.38M1.18%+1,243,039New
Price T Rowe Associates Inc1,104,385$5.67M0.00%+69,733+6.7%Added
Kennedy Capital Management, Inc.1,091,834$5.60M0.12%−359,061−24.7%Reduced
Northern Trust Corp1,029,750$5.28M0.00%+239,685+30.3%Added
Mutual of America Capital Management LLC1,029,680$5.28M0.06%+370,426+56.2%Added
Eventide Asset Management, LLC1,017,928$5.22M0.10%+1,017,928New
Massachusetts Financial Services Co1,016,566$5.21M0.00%−144,320−12.4%Reduced
Ameriprise Financial Inc926,642$4.75M0.00%+767,869+483.6%Added
Readystate Asset Management LP774,860$3.98M0.17%00.0%Unchanged
Charles Schwab Investment Management Inc743,795$3.82M0.00%+11,579+1.6%Added
Walleye Capital LLC656,332$3.37M0.03%+327,634+99.7%Added
Morgan Stanley644,677$3.31M0.00%−590,808−47.8%Reduced
Deerfield Management Company, L.P. (Series C)583,913$3.00M0.06%00.0%Unchanged
Rhenman & Partners Asset Management AB542,500$2.78M0.29%−17,500−3.1%Reduced
Deutsche Bank AG536,503$2.75M0.00%+28,448+5.6%Added
Renaissance Technologies LLC493,700$2.53M0.00%+92,300+23.0%Added
Board of Trustees of The Leland Stanford Junior University482,550$2.48M0.21%00.0%Unchanged
Qube Research & Technologies Ltd461,372$2.37M0.00%+31,813+7.4%Added
Hennion & Walsh Asset Management, Inc.429,584$2.20M0.10%+170,180+65.6%Added
Parkman Healthcare Partners LLC330,849$1.70M0.23%+2,236+0.7%Added
UBS Group AG328,721$1.69M0.00%+109,594+50.0%Added
UBS Oconnor LLC318,884$1.64M0.04%−1,690−0.5%Reduced
Wellington Management Group LLP268,166$1.38M0.00%+4,806+1.8%Added
Wells Fargo & Company235,755$1.21M0.00%+17,541+8.0%Added
Bank of New York Mellon Corp230,546$1.18M0.00%+6,226+2.8%Added
Rafferty Asset Management, LLC218,369$1.12M0.00%+41,544+23.5%Added
Barclays PLC206,991$1.06M0.00%+29,226+16.4%Added
American Century Companies Inc178,511$915.8K0.00%+34,297+23.8%Added
Artia Global Partners LP172,226$883.5K0.36%00.0%Unchanged
Prudential Financial Inc171,680$880.7K0.00%+10,400+6.4%Added
Citigroup Inc168,787$865.9K0.00%+98,781+141.1%Added
Manufacturers Life Insurance Company, The159,019$815.8K0.00%−567−0.4%Reduced
J. Safra Sarasin Holding AG155,744$799.0K0.01%+155,744New
Millennium Management LLC155,676$798.6K0.00%+83,021+114.3%Added
Point72 Europe (London) LLP155,573$798.1K0.05%−4,380−2.7%Reduced
Acadian Asset Management LLC155,645$798.0K0.00%−789,351−83.5%Reduced
Exome Asset Management LLC144,830$743.0K0.56%+144,830New
Rhumbline Advisers141,852$727.7K0.00%+5,854+4.3%Added
Two Sigma Investments, LP137,183$703.7K0.00%−3,734−2.6%Reduced
Cinctive Capital Management LP135,466$694.9K0.04%−51,362−27.5%Reduced
Swiss National Bank135,000$692.5K0.00%+135,000New
TD Asset Management Inc133,648$685.6K0.00%00.0%Unchanged
Susquehanna Fundamental Investments, LLC119,725$614.2K0.01%+119,725New
Park Avenue Securities LLC118,068$606.0K0.01%00.0%Unchanged
Alliancebernstein L.P.111,300$571.0K0.00%−16,060−12.6%Reduced
Driehaus Capital Management LLC258,314$547.4K0.00%00.0%Unchanged
Jane Street Group, LLC92,371$473.9K0.00%+25,507+38.1%Added
Alps Advisors Inc86,194$442.2K0.00%+11,850+15.9%Added
Legal & General Group Plc85,535$438.8K0.00%+71,665+516.7%Added
ExodusPoint Capital Management, LP83,437$428.0K0.00%+83,437New
Advisor Group Holdings, Inc.80,475$412.8K0.00%+17,850+28.5%Added
State of Wisconsin Investment Board69,248$355.2K0.00%+43,293+166.8%Added
California State Teachers Retirement System66,375$340.5K0.00%+59,381+849.0%Added
MetLife Investment Management64,967$333.3K0.00%+9,755+17.7%Added
Mirae Asset Global ETFs Holdings Ltd.63,402$325.3K0.00%+4,092+6.9%Added
Susquehanna International Group, LLP62,841$322.4K0.00%+31,677+101.6%Added
Quarry LP58,000$297.5K0.06%+38,000+190.0%Added
Squarepoint Ops LLC57,153$293.2K0.00%−49,438−46.4%Reduced
Franklin Resources Inc49,324$253.0K0.00%−82−0.2%Reduced
UBS Asset Management Americas Inc49,062$251.7K0.00%+49,062New
Corebridge Financial, Inc.48,547$249.0K0.00%−2,591−5.1%Reduced
DnB Asset Management AS47,665$244.5K0.00%+861+1.8%Added
Schonfeld Strategic Advisors LLC47,300$242.6K0.00%−589,091−92.6%Reduced
Intech Investment Management LLC45,726$234.6K0.00%+19,713+75.8%Added
Prelude Capital Management, LLC43,363$222.5K0.02%+43,363New
Profund Advisors LLC42,273$216.9K0.01%+6,826+19.3%Added
Marshall Wace, LLP38,845$199.3K0.00%−253,529−86.7%Reduced
XTX Topco Ltd35,151$180.3K0.02%+35,151New
Janus Henderson Group PLC34,500$177.2K0.00%+34,500New
New York State Common Retirement Fund34,479$176.9K0.00%+20,311+143.4%Added
AQR Capital Management LLC33,153$170.1K0.00%−31,638−48.8%Reduced
ProShare Advisors LLC32,548$167.0K0.00%+14,475+80.1%Added
Invesco Ltd.31,881$163.6K0.00%+10,611+49.9%Added
Shay Capital LLC31,000$159.0K0.04%+31,000New
SG Americas Securities, LLC30,968$159.0K0.00%−1,795−5.5%Reduced
HSBC Holdings PLC30,799$156.5K0.00%−7,026−18.6%Reduced
Sherbrooke Park Advisers LLC30,134$154.6K0.05%−12,897−30.0%Reduced
Bank of America Corp29,940$153.6K0.00%−137,220−82.1%Reduced
Simplex Trading, LLC29,433$150.0K0.00%+3,603+13.9%Added
Voya Investment Management LLC28,589$146.7K0.00%−1,441−4.8%Reduced