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Annexon, Inc.

ANNX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001528115

In the last 90 days, Annexon, Inc. insiders filed 1 open-market purchase and 0 sales; 216 institutions reported holding it in 13F filings for Q2 2026, worth $1.02B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Annexon, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
129
−19 vs. Q1 2025
Shares held
99.7M
−42.6K (0.0%) vs. Q1 2025
Total value
$238.7M
+$46.6M (+24.2%) vs. Q1 2025
New holders
18
51 more added
Sold out
37
34 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANNX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 129 institutions
Q1 2021: 72 institutionsQ2 2021: 74 institutionsQ3 2021: 82 institutionsQ4 2021: 97 institutionsQ1 2022: 100 institutionsQ2 2022: 78 institutionsQ3 2022: 72 institutionsQ4 2022: 84 institutionsQ1 2023: 100 institutionsQ2 2023: 95 institutionsQ3 2023: 93 institutionsQ4 2023: 99 institutionsQ1 2024: 127 institutionsQ2 2024: 140 institutionsQ3 2024: 142 institutionsQ4 2024: 153 institutionsQ1 2025: 148 institutionsQ2 2025: 129 institutionsQ3 2025: 144 institutionsQ4 2025: 168 institutionsQ1 2026: 217 institutionsQ2 2026: 216 institutions
Value heldQ2 2025: $238.7M
Q1 2021: $1.04BQ2 2021: $873.7MQ3 2021: $708.6MQ4 2021: $445.7MQ1 2022: $105.9MQ2 2022: $144.9MQ3 2022: $292.3MQ4 2022: $243.3MQ1 2023: $207.6MQ2 2023: $190.0MQ3 2023: $126.0MQ4 2023: $365.7MQ1 2024: $679.4MQ2 2024: $526.9MQ3 2024: $651.8MQ4 2024: $574.6MQ1 2025: $192.1MQ2 2025: $238.7MQ3 2025: $309.2MQ4 2025: $687.2MQ1 2026: $863.7MQ2 2026: $1.02B
Institutions holding ANNX and their total value by quarter
QuarterHoldersValue
Q2 2026216$1.02B
Q1 2026217$863.7M
Q4 2025168$687.2M
Q3 2025144$309.2M
Q2 2025129$238.7M
Q1 2025148$192.1M
Q4 2024153$574.6M
Q3 2024142$651.8M
Q2 2024140$526.9M
Q1 2024127$679.4M
Q4 202399$365.7M
Q3 202393$126.0M
Q2 202395$190.0M
Q1 2023100$207.6M
Q4 202284$243.3M
Q3 202272$292.3M
Q2 202278$144.9M
Q1 2022100$105.9M
Q4 202197$445.7M
Q3 202182$708.6M
Q2 202174$873.7M
Q1 202172$1.04B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Annexon, Inc.; share changes are against Q1 2025.

Institutions holding ANNX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC15,695,226$37.7M0.00%+2,432,898+18.3%Added
BlackRock, Inc.7,962,368$19.1M0.00%−564,138−6.6%Reduced
BVF Inc7,000,000$16.8M0.60%00.0%Unchanged
Redmile Group, LLC6,300,644$15.1M1.61%00.0%Unchanged
Vanguard Group Inc5,366,039$12.9M0.00%−13,620−0.3%Reduced
Bain Capital Life Sciences Investors, LLC5,249,069$12.6M1.58%00.0%Unchanged
Bellevue Group AG5,157,290$12.4M0.27%00.0%Unchanged
Sio Capital Management, LLC4,095,764$9.83M3.94%+697,978+20.5%Added
Polygon Management Ltd.2,810,000$6.74M1.22%+160,000+6.0%Added
Candriam Luxembourg S.C.A.2,534,230$6.08M0.04%00.0%Unchanged
Millennium Management LLC2,514,134$6.03M0.01%+2,338,831+1,334.2%Added
Logos Global Management LP2,410,000$5.78M0.77%−1,590,000−39.8%Reduced
Geode Capital Management, LLC2,284,773$5.48M0.00%+39,763+1.8%Added
Ameriprise Financial Inc2,166,178$5.20M0.00%−1,819,117−45.6%Reduced
State Street Corp1,980,984$4.75M0.00%−58,842−2.9%Reduced
Sphera Funds Management Ltd.1,764,387$4.23M1.11%00.0%Unchanged
Goldman Sachs Group Inc1,630,649$3.91M0.00%+789,067+93.8%Added
Bank of America Corp1,452,795$3.49M0.00%+414,071+39.9%Added
Mutual of America Capital Management LLC1,078,961$2.59M0.03%+48,278+4.7%Added
Woodline Partners LP1,053,709$2.53M0.01%−1,060,987−50.2%Reduced
Sirios Capital Management L P989,577$2.37M0.34%+220,891+28.7%Added
Massachusetts Financial Services Co987,513$2.37M0.00%−32,904−3.2%Reduced
Dimensional Fund Advisors LP889,863$2.14M0.00%−97,016−9.8%Reduced
Kennedy Capital Management, Inc.855,573$2.05M0.05%−19,153−2.2%Reduced
Morgan Stanley832,540$2.00M0.00%+131,184+18.7%Added
Walleye Capital LLC794,639$1.91M0.02%−8,274−1.0%Reduced
Renaissance Technologies LLC777,900$1.87M0.00%−384,537−33.1%Reduced
Northern Trust Corp743,224$1.78M0.00%−282,701−27.6%Reduced
Charles Schwab Investment Management Inc728,389$1.75M0.00%+2,637+0.4%Added
Deerfield Management Company, L.P. (Series C)583,913$1.40M0.03%00.0%Unchanged
Deutsche Bank AG511,448$1.23M0.00%−25,846−4.8%Reduced
Price T Rowe Associates Inc508,103$1.22M0.00%−16,638−3.2%Reduced
UBS Oconnor LLC492,698$1.18M0.03%+25,879+5.5%Added
Hennion & Walsh Asset Management, Inc.484,633$1.16M0.05%+7,066+1.5%Added
Board of Trustees of The Leland Stanford Junior University482,550$1.16M0.13%00.0%Unchanged
Acadian Asset Management LLC469,209$1.13M0.00%+265,219+130.0%Added
Rhenman & Partners Asset Management AB460,000$1.10M0.14%00.0%Unchanged
Qube Research & Technologies Ltd424,720$1.02M0.00%−312,548−42.4%Reduced
Parkman Healthcare Partners LLC404,194$970.1K0.11%+52,758+15.0%Added
J. Safra Sarasin Holding AG381,441$915.5K0.02%+126,903+49.9%Added
Wells Fargo & Company376,974$904.7K0.00%+29,082+8.4%Added
AQR Capital Management LLC332,031$796.9K0.00%+258,241+350.0%Added
UBS Group AG325,122$780.3K0.00%+57,774+21.6%Added
Bank of New York Mellon Corp301,048$722.5K0.00%+12,350+4.3%Added
Susquehanna International Group, LLP266,812$640.3K0.00%+67,587+33.9%Added
Schonfeld Strategic Advisors LLC266,050$638.5K0.00%+154,849+139.3%Added
Nuveen, LLC255,918$614.2K0.00%−91,114−26.3%Reduced
Royal Bank of Canada245,199$588.0K0.00%+238,365+3,487.9%Added
American Century Companies Inc211,195$506.9K0.00%+13,001+6.6%Added
Susquehanna Portfolio Strategies, LLC207,715$498.5K0.01%+207,715New
Point72 Europe (London) LLP206,798$496.3K0.03%+163,076+373.0%Added
Two Sigma Investments, LP201,160$482.8K0.00%+201,160New
Barclays PLC177,628$426.3K0.00%+12,496+7.6%Added
Invesco Ltd.150,414$361.0K0.00%+59,005+64.6%Added
Jane Street Group, LLC145,869$350.1K0.00%+45,945+46.0%Added
Alliancebernstein L.P.140,740$337.8K0.00%+29,440+26.5%Added
Rhumbline Advisers137,536$330.1K0.00%+1,136+0.8%Added
Ieq Capital, LLC135,797$325.9K0.00%+55,797+69.7%Added
Cinctive Capital Management LP135,466$325.1K0.02%00.0%Unchanged
Manufacturers Life Insurance Company, The134,035$321.7K0.00%−527−0.4%Reduced
Park Avenue Securities LLC113,068$271.0K0.00%+30,000+36.1%Added
DnB Asset Management AS99,574$239.0K0.00%+25,195+33.9%Added
Bridgeway Capital Management, LLC97,800$234.7K0.01%+97,800New
UBS Asset Management Americas Inc93,500$224.4K0.00%+14,643+18.6%Added
Advisor Group Holdings, Inc.80,375$192.9K0.00%+80,375New
Natixis77,100$185.0K0.00%+77,100New
ExodusPoint Capital Management, LP61,691$148.0K0.00%−121,596−66.3%Reduced
Alps Advisors Inc59,201$142.1K0.00%−23,425−28.4%Reduced
MetLife Investment Management59,022$141.7K0.00%+21,611+57.8%Added
Brevan Howard Capital Management LP53,283$127.9K0.00%−8,791−14.2%Reduced
JPMorgan Chase & Co52,819$126.8K0.00%−1,379,146−96.3%Reduced
Intech Investment Management LLC52,699$126.5K0.00%−14,566−21.7%Reduced
Mirae Asset Global ETFs Holdings Ltd.52,405$125.8K0.00%−4,858−8.5%Reduced
TD Asset Management Inc46,848$112.4K0.00%00.0%Unchanged
Quarry LP43,133$103.5K0.02%+22,133+105.4%Added
Allegheny Financial Group LTD42,900$103.0K0.02%+17,700+70.2%Added
Citigroup Inc37,796$90.7K0.00%−36,868−49.4%Reduced
Lido Advisors, LLC35,000$84.0K0.00%+15,000+75.0%Added
Citizens Financial Group Inc35,000$84.0K0.00%+35,000New
Virtus Investment Advisers, Inc.34,698$83.3K0.03%−1,701−4.7%Reduced
New York State Common Retirement Fund34,479$82.8K0.00%00.0%Unchanged
Virtu Financial LLC30,597$73.0K0.00%+30,597New
HSBC Holdings PLC29,855$72.3K0.00%−7,080−19.2%Reduced
Marshall Wace, LLP29,989$72.0K0.00%+29,989New
Forefront Analytics, LLC27,575$66.2K0.07%−1,016−3.6%Reduced
Voya Investment Management LLC27,455$65.9K0.00%00.0%Unchanged
Comerica Bank25,607$61.5K0.00%00.0%Unchanged
ProShare Advisors LLC23,732$57.0K0.00%−2,216−8.5%Reduced
China Universal Asset Management Co., Ltd.22,036$52.9K0.00%+655+3.1%Added
Police & Firemen's Retirement System of New Jersey20,587$49.4K0.00%00.0%Unchanged
Quadrature Capital Ltd20,515$49.1K0.00%+2,783+15.7%Added
Driehaus Capital Management LLC258,314$48.6K0.00%00.0%Unchanged
Los Angeles Capital Management LLC20,196$48.5K0.00%+20,196New
CWM, LLC17,734$43.0K0.00%+12,066+212.9%Added
Coastal Bridge Advisors, LLC17,000$40.8K0.00%00.0%Unchanged
State Board of Administration of Florida Retirement System15,607$37.5K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)15,558$37.3K0.00%−10,546−40.4%Reduced
Engineers Gate Manager LP13,401$32.2K0.00%+13,401New
Citadel Advisors LLC13,267$31.8K0.00%+812+6.5%Added
JustInvest LLC12,284$29.5K0.00%+12,284New