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Annexon, Inc.

ANNX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001528115

In the last 90 days, Annexon, Inc. insiders filed 1 open-market purchase and 0 sales; 216 institutions reported holding it in 13F filings for Q2 2026, worth $1.02B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Annexon, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
148
−3 vs. Q4 2024
Shares held
99.8M
−2.29M (−2.2%) vs. Q4 2024
Total value
$192.1M
−$330.5M (−63.2%) vs. Q4 2024
New holders
25
55 more added
Sold out
28
40 more reduced

2 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANNX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 148 institutions
Q1 2021: 72 institutionsQ2 2021: 74 institutionsQ3 2021: 82 institutionsQ4 2021: 97 institutionsQ1 2022: 100 institutionsQ2 2022: 78 institutionsQ3 2022: 72 institutionsQ4 2022: 84 institutionsQ1 2023: 100 institutionsQ2 2023: 95 institutionsQ3 2023: 93 institutionsQ4 2023: 99 institutionsQ1 2024: 127 institutionsQ2 2024: 140 institutionsQ3 2024: 142 institutionsQ4 2024: 153 institutionsQ1 2025: 148 institutionsQ2 2025: 129 institutionsQ3 2025: 144 institutionsQ4 2025: 168 institutionsQ1 2026: 217 institutionsQ2 2026: 216 institutions
Value heldQ1 2025: $192.1M
Q1 2021: $1.04BQ2 2021: $873.7MQ3 2021: $708.6MQ4 2021: $445.7MQ1 2022: $105.9MQ2 2022: $144.9MQ3 2022: $292.3MQ4 2022: $243.3MQ1 2023: $207.6MQ2 2023: $190.0MQ3 2023: $126.0MQ4 2023: $365.7MQ1 2024: $679.4MQ2 2024: $526.9MQ3 2024: $651.8MQ4 2024: $574.6MQ1 2025: $192.1MQ2 2025: $238.7MQ3 2025: $309.2MQ4 2025: $687.2MQ1 2026: $863.7MQ2 2026: $1.02B
Institutions holding ANNX and their total value by quarter
QuarterHoldersValue
Q2 2026216$1.02B
Q1 2026217$863.7M
Q4 2025168$687.2M
Q3 2025144$309.2M
Q2 2025129$238.7M
Q1 2025148$192.1M
Q4 2024153$574.6M
Q3 2024142$651.8M
Q2 2024140$526.9M
Q1 2024127$679.4M
Q4 202399$365.7M
Q3 202393$126.0M
Q2 202395$190.0M
Q1 2023100$207.6M
Q4 202284$243.3M
Q3 202272$292.3M
Q2 202278$144.9M
Q1 2022100$105.9M
Q4 202197$445.7M
Q3 202182$708.6M
Q2 202174$873.7M
Q1 202172$1.04B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Annexon, Inc.; share changes are against Q4 2024.

Institutions holding ANNX in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC13,262,328$25.6M0.00%−962,055−6.8%Reduced
BlackRock, Inc.8,526,506$16.5M0.00%+40,319+0.5%Added
BVF Inc7,000,000$13.5M0.55%00.0%Unchanged
Redmile Group, LLC6,300,644$12.2M1.15%00.0%Unchanged
Vanguard Group Inc5,379,659$10.4M0.00%−167,259−3.0%Reduced
Bain Capital Life Sciences Investors, LLC5,249,069$10.1M1.50%00.0%Unchanged
Bellevue Group AG5,157,290$9.95M0.22%00.0%Unchanged
Logos Global Management LP4,000,000$7.72M1.37%+1,450,000+56.9%Added
Ameriprise Financial Inc3,985,295$7.69M0.00%+3,058,653+330.1%Added
Sio Capital Management, LLC3,397,786$6.56M1.99%+1,030,779+43.5%Added
Polygon Management Ltd.2,650,000$5.11M1.64%+1,250,000+89.3%Added
Candriam Luxembourg S.C.A.2,534,230$4.89M0.03%00.0%Unchanged
Geode Capital Management, LLC2,245,010$4.33M0.00%+73,532+3.4%Added
Woodline Partners LP2,114,696$4.08M0.03%−576,091−21.4%Reduced
State Street Corp2,039,826$3.94M0.00%−2,470,888−54.8%Reduced
Sphera Funds Management Ltd.1,764,387$3.41M0.84%+521,348+41.9%Added
JPMorgan Chase & Co1,431,965$2.76M0.00%−79,552−5.3%Reduced
Renaissance Technologies LLC1,162,437$2.24M0.00%+668,737+135.5%Added
Bank of America Corp1,038,724$2.00M0.00%+1,008,784+3,369.4%Added
Mutual of America Capital Management LLC1,030,683$1.99M0.02%+1,003+0.1%Added
Northern Trust Corp1,025,925$1.98M0.00%−3,825−0.4%Reduced
Massachusetts Financial Services Co1,020,417$1.97M0.00%+3,851+0.4%Added
Dimensional Fund Advisors LP986,879$1.91M0.00%−373,197−27.4%Reduced
Kennedy Capital Management, Inc.874,726$1.69M0.04%−217,108−19.9%Reduced
Goldman Sachs Group Inc841,582$1.62M0.00%−475,429−36.1%Reduced
Walleye Capital LLC802,913$1.55M0.02%+146,581+22.3%Added
Sirios Capital Management L P768,686$1.48M0.26%+768,686New
Qube Research & Technologies Ltd737,268$1.42M0.00%+275,896+59.8%Added
Charles Schwab Investment Management Inc725,752$1.40M0.00%−18,043−2.4%Reduced
Morgan Stanley701,356$1.35M0.00%+56,679+8.8%Added
Deerfield Management Company, L.P. (Series C)583,913$1.13M0.02%00.0%Unchanged
Deutsche Bank AG537,294$1.04M0.00%+791+0.1%Added
Price T Rowe Associates Inc524,741$1.01M0.00%−579,644−52.5%Reduced
Board of Trustees of The Leland Stanford Junior University482,550$931.3K0.08%00.0%Unchanged
Hennion & Walsh Asset Management, Inc.477,567$921.7K0.04%+47,983+11.2%Added
UBS Oconnor LLC466,819$901.0K0.02%+147,935+46.4%Added
Rhenman & Partners Asset Management AB460,000$887.8K0.10%−82,500−15.2%Reduced
Wellington Management Group LLP356,480$688.0K0.00%+88,314+32.9%Added
Parkman Healthcare Partners LLC351,436$678.3K0.08%+20,587+6.2%Added
Wells Fargo & Company347,892$671.4K0.00%+112,137+47.6%Added
Nuveen, LLC347,032$669.8K0.00%+347,032New
Bank of New York Mellon Corp288,698$557.2K0.00%+58,152+25.2%Added
UBS Group AG267,348$516.0K0.00%−61,373−18.7%Reduced
J. Safra Sarasin Holding AG254,538$491.3K0.01%+98,794+63.4%Added
Acadian Asset Management LLC203,990$393.0K0.00%+48,345+31.1%Added
Susquehanna International Group, LLP199,225$384.5K0.00%+136,384+217.0%Added
American Century Companies Inc198,194$382.5K0.00%+19,683+11.0%Added
ExodusPoint Capital Management, LP183,287$354.0K0.00%+99,850+119.7%Added
Millennium Management LLC175,303$338.3K0.00%+19,627+12.6%Added
Barclays PLC165,132$318.7K0.00%−41,859−20.2%Reduced
Syon Capital LLC144,485$278.9K0.02%+144,485New
Rhumbline Advisers136,400$263.2K0.00%−5,452−3.8%Reduced
Cinctive Capital Management LP135,466$261.4K0.02%00.0%Unchanged
Swiss National Bank135,000$260.6K0.00%00.0%Unchanged
Manufacturers Life Insurance Company, The134,562$259.7K0.00%−24,457−15.4%Reduced
Squarepoint Ops LLC132,997$256.7K0.00%+75,844+132.7%Added
Alliancebernstein L.P.111,300$214.8K0.00%00.0%Unchanged
Schonfeld Strategic Advisors LLC111,201$214.6K0.00%+63,901+135.1%Added
Jane Street Group, LLC99,924$192.9K0.00%+7,553+8.2%Added
Balyasny Asset Management LLC96,752$186.7K0.00%+96,752New
Invesco Ltd.91,409$176.4K0.00%+59,528+186.7%Added
Legal & General Group Plc85,535$165.1K0.00%00.0%Unchanged
Park Avenue Securities LLC83,068$160.0K0.00%−35,000−29.6%Reduced
Alps Advisors Inc82,626$159.5K0.00%−3,568−4.1%Reduced
State of Wisconsin Investment Board81,636$157.6K0.00%+12,388+17.9%Added
Ieq Capital, LLC80,000$154.4K0.00%+80,000New
UBS Asset Management Americas Inc78,857$152.2K0.00%+29,795+60.7%Added
HRT Financial LP78,100$150.0K0.00%+78,100New
Citigroup Inc74,664$144.1K0.00%−94,123−55.8%Reduced
DnB Asset Management AS74,379$143.6K0.00%+26,714+56.0%Added
AQR Capital Management LLC73,790$142.4K0.00%+40,637+122.6%Added
Intech Investment Management LLC67,265$129.8K0.00%+21,539+47.1%Added
California State Teachers Retirement System66,375$128.1K0.00%00.0%Unchanged
Y-Intercept (Hong Kong) Ltd65,918$127.2K0.01%+65,918New
SG Americas Securities, LLC63,161$122.0K0.00%+32,193+104.0%Added
Brevan Howard Capital Management LP62,074$119.8K0.00%+62,074New
Jain Global LLC61,276$118.3K0.00%+61,276New
XTX Topco Ltd58,130$112.2K0.01%+22,979+65.4%Added
Mirae Asset Global ETFs Holdings Ltd.57,263$110.5K0.00%−6,139−9.7%Reduced
Prudential Financial Inc57,120$110.2K0.00%−114,560−66.7%Reduced
Driehaus Capital Management LLC258,314$104.3K0.00%00.0%Unchanged
EntryPoint Capital, LLC53,271$102.8K0.05%+53,271New
Franklin Resources Inc49,123$94.8K0.00%−201−0.4%Reduced
Corebridge Financial, Inc.47,838$92.3K0.00%−709−1.5%Reduced
TD Asset Management Inc46,848$90.4K0.00%−86,800−64.9%Reduced
Point72 Asset Management, L.P.45,714$88.2K0.00%−5,581,082−99.2%Reduced
Point72 Europe (London) LLP43,722$84.4K0.01%−111,851−71.9%Reduced
Susquehanna Fundamental Investments, LLC41,011$79.2K0.00%−78,714−65.7%Reduced
Janus Henderson Group PLC34,500$77.8K0.00%00.0%Unchanged
HSBC Holdings PLC36,935$72.9K0.00%+6,136+19.9%Added
MetLife Investment Management37,411$72.2K0.00%−27,556−42.4%Reduced
Virtus Investment Advisers, Inc.36,399$70.3K0.02%+36,399New
Shay Capital LLC35,162$67.9K0.02%+4,162+13.4%Added
New York State Common Retirement Fund34,479$66.5K0.00%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)34,026$65.7K0.00%+21,143+164.1%Added
Forefront Analytics, LLC28,591$55.3K0.06%+12,158+74.0%Added
Voya Investment Management LLC27,455$53.0K0.00%−1,134−4.0%Reduced
Tower Research Capital LLC (TRC)26,104$50.4K0.00%+1,212+4.9%Added
ProShare Advisors LLC25,948$50.1K0.00%−6,600−20.3%Reduced
Comerica Bank25,607$49.4K0.00%+2,424+10.5%Added