Skip to main content
Livermore
Livermore
ZHEN

Annexon, Inc.

ANNX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001528115

In the last 90 days, Annexon, Inc. insiders filed 1 open-market purchase and 0 sales; 216 institutions reported holding it in 13F filings for Q2 2026, worth $1.02B in total; no superinvestor holds it.

Q4 2025 vs. Q3 2025

How the institutions holding Annexon, Inc. changed between Q3 2025 and Q4 2025.

All holders in Q4 2025All holders in Q3 2025

13F holders of ANNX: Q3 2025 compared with Q4 2025
MeasureQ3 2025Of which not filed for Q4 2025Q4 2025Change
Holders1443168+27
Shares101.4M335.8K136.9M+35.9M (+35.5%)
Value$309.2M$1.02M$687.2M+$379.0M (+123.0%)

3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (41)

Institutions that held Annexon, Inc. at the end of Q4 2025 but not at the end of Q3 2025.

Institutions new to ANNX in Q4 2025
InstitutionSharesValue% of portfolio
Longaeva Partners L.P.3,100,000$15.6M1.85%
Mak Capital One LLC2,958,527$14.9M2.00%
Palo Alto Investors LP2,384,192$12.0M1.67%
D. E. Shaw & Co., Inc.1,046,221$5.25M0.00%
Ishara Investments LP750,000$3.77M4.38%
Marshall Wace, LLP520,998$2.62M0.00%
Wellington Management Group LLP398,077$2.00M0.00%
Diadema Partners LP350,000$1.76M1.05%
DAFNA Capital Management LLC272,812$1.37M0.32%
Ikarian Capital, LLC230,244$1.16M0.15%
Rafferty Asset Management, LLC141,644$711.1K0.00%
Jump Financial, LLC122,858$616.7K0.01%
Caption Management, LLC119,491$599.8K0.03%
Persistent Asset Partners Ltd93,657$470.2K0.23%
Boothbay Fund Management, LLC64,069$321.6K0.01%
SEI Investments Co58,259$292.5K0.00%
Winton Group Ltd53,400$268.1K0.01%
Profund Advisors LLC53,008$266.1K0.01%
Quadrature Capital Ltd48,573$243.8K0.00%
ADAR1 Capital Management, LLC48,000$241.0K0.02%
Pale Fire Capital SE38,600$193.8K0.02%
Landing Point Financial Group, LLC34,900$175.2K0.09%
Captrust Financial Advisors31,585$158.6K0.00%
Mariner, LLC31,335$157.4K0.00%
Caitong International Asset Management Co., Ltd19,197$96.4K0.02%
Canada Pension Plan Investment Board17,600$88.4K0.00%
Scientech Research LLC17,216$86.4K0.05%
Cerity Partners LLC14,801$74.3K0.00%
Prelude Capital Management, LLC12,000$60.2K0.00%
Cygnus Capital Advisors, LLC12,000$60.0K0.04%
Mount Vernon Associates Inc10,500$53.0K0.04%
Mercer Global Advisors Inc10,386$52.1K0.00%
Simplex Trading, LLC10,268$51.5K0.00%
Landscape Capital Management, L.L.C.10,016$50.3K0.00%
Jones Financial Companies LLLP2,987$15.0K0.00%
Larson Financial Group LLC2,000$10.0K0.00%
Federated Hermes, Inc.753$3.78K0.00%
Rockefeller Capital Management L.P.334$1.68K0.00%
Assetmark, Inc333$1.67K0.00%
MAI Capital Management63$3170.00%
Northwestern Mutual Wealth Management Co4$200.00%

Sold out (14)

Institutions that held Annexon, Inc. at the end of Q3 2025 and filed for Q4 2025 without it.

Institutions that sold out of ANNX in Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
Candriam Luxembourg S.C.A.2,534,230$7.73M
Rhenman & Partners Asset Management AB823,000$2.51M
ExodusPoint Capital Management, LP243,755$743.5K
Park Avenue Securities LLC113,068$345.0K
HRT Financial LP84,582$257.0K
Alps Advisors Inc47,879$146.0K
Atom Investors LP30,453$92.9K
Forefront Wealth Partners, LLC27,027$82.4K
Two Sigma Advisers, LP23,800$72.6K
Matauro, LLC20,572$62.7K
49 Wealth Management, LLC12,083$36.9K
Prudential Financial Inc11,670$35.6K
Clearstead Advisors, LLC355$1.08K
Advisory Services Network, LLC23$70

Not filed for Q4 2025 yet (3)

Institutions that held Annexon, Inc. at the end of Q3 2025 and haven't filed a 13F for Q4 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding ANNX in Q3 2025 that haven't filed for Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
Point72 Europe (London) LLP302,861$923.7K
Cubist Systematic Strategies, LLC22,771$69.5K
CIBC Bancorp USA Inc.10,208$31.1K