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Annexon, Inc.

ANNX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001528115

In the last 90 days, Annexon, Inc. insiders filed 1 open-market purchase and 0 sales; 216 institutions reported holding it in 13F filings for Q2 2026, worth $1.02B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Annexon, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
168
+27 vs. Q3 2025
Shares held
136.9M
+35.9M (+35.5%) vs. Q3 2025
Total value
$687.2M
+$379.0M (+123.0%) vs. Q3 2025
New holders
41
72 more added
Sold out
14
30 more reduced

3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANNX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 168 institutions
Q1 2021: 72 institutionsQ2 2021: 74 institutionsQ3 2021: 82 institutionsQ4 2021: 97 institutionsQ1 2022: 100 institutionsQ2 2022: 78 institutionsQ3 2022: 72 institutionsQ4 2022: 84 institutionsQ1 2023: 100 institutionsQ2 2023: 95 institutionsQ3 2023: 93 institutionsQ4 2023: 99 institutionsQ1 2024: 127 institutionsQ2 2024: 140 institutionsQ3 2024: 142 institutionsQ4 2024: 153 institutionsQ1 2025: 148 institutionsQ2 2025: 129 institutionsQ3 2025: 144 institutionsQ4 2025: 168 institutionsQ1 2026: 217 institutionsQ2 2026: 216 institutions
Value heldQ4 2025: $687.2M
Q1 2021: $1.04BQ2 2021: $873.7MQ3 2021: $708.6MQ4 2021: $445.7MQ1 2022: $105.9MQ2 2022: $144.9MQ3 2022: $292.3MQ4 2022: $243.3MQ1 2023: $207.6MQ2 2023: $190.0MQ3 2023: $126.0MQ4 2023: $365.7MQ1 2024: $679.4MQ2 2024: $526.9MQ3 2024: $651.8MQ4 2024: $574.6MQ1 2025: $192.1MQ2 2025: $238.7MQ3 2025: $309.2MQ4 2025: $687.2MQ1 2026: $863.7MQ2 2026: $1.02B
Institutions holding ANNX and their total value by quarter
QuarterHoldersValue
Q2 2026216$1.02B
Q1 2026217$863.7M
Q4 2025168$687.2M
Q3 2025144$309.2M
Q2 2025129$238.7M
Q1 2025148$192.1M
Q4 2024153$574.6M
Q3 2024142$651.8M
Q2 2024140$526.9M
Q1 2024127$679.4M
Q4 202399$365.7M
Q3 202393$126.0M
Q2 202395$190.0M
Q1 2023100$207.6M
Q4 202284$243.3M
Q3 202272$292.3M
Q2 202278$144.9M
Q1 2022100$105.9M
Q4 202197$445.7M
Q3 202182$708.6M
Q2 202174$873.7M
Q1 202172$1.04B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Annexon, Inc.; share changes are against Q3 2025.

Institutions holding ANNX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Northwestern Mutual Wealth Management Co4$200.00%+4New
SRS Capital Advisors, Inc.19$950.00%−6,511−99.7%Reduced
SBI Securities Co., Ltd.25$1260.00%−1−3.8%Reduced
MAI Capital Management63$3170.00%+63New
Sunbelt Securities, Inc.110$5520.00%+23+26.4%Added
True Wealth Design, LLC211$1.06K0.00%+156+283.6%Added
Rothschild Investment LLC236$1.19K0.00%+71+43.0%Added
UMA Financial Services, Inc.269$1.35K0.00%00.0%Unchanged
HighMark Wealth Management LLC300$1.51K0.00%00.0%Unchanged
Farther Finance Advisors, LLC309$1.55K0.00%+308+30,800.0%Added
Assetmark, Inc333$1.67K0.00%+333New
Rockefeller Capital Management L.P.334$1.68K0.00%+334New
Daiwa Securities Group Inc.352$2.00K0.00%00.0%Unchanged
Allworth Financial LP416$2.09K0.00%+264+173.7%Added
Optiver Holding B.V.530$2.66K0.00%−774−59.4%Reduced
EverSource Wealth Advisors, LLC539$2.71K0.00%+243+82.1%Added
IFP Advisors, Inc547$2.75K0.00%+197+56.3%Added
Federated Hermes, Inc.753$3.78K0.00%+753New
Essential Partners LLC1,087$5.46K0.00%+794+271.0%Added
The PNC Financial Services Group, Inc.1,132$5.68K0.00%+9+0.8%Added
Tower Research Capital LLC (TRC)1,966$9.87K0.00%−4,130−67.7%Reduced
Larson Financial Group LLC2,000$10.0K0.00%+2,000New
Nisa Investment Advisors, LLC2,613$13.1K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.2,843$14.3K0.00%+479+20.3%Added
Jones Financial Companies LLLP2,987$15.0K0.00%+2,987New
Royal Bank of Canada2,855$15.0K0.00%−282,993−99.0%Reduced
Amalgamated Bank3,144$16.0K0.00%−226−6.7%Reduced
Sterling Capital Management LLC5,967$30.0K0.00%−640−9.7%Reduced
Geneos Wealth Management Inc.6,000$30.1K0.00%00.0%Unchanged
California State Teachers Retirement System6,163$30.9K0.00%+168+2.8%Added
Mirae Asset Global Investments Co., Ltd.7,033$35.3K0.00%+2,785+65.6%Added
Legal & General Group Plc9,307$46.7K0.00%+831+9.8%Added
Ameritas Investment Partners, Inc.9,689$48.6K0.00%00.0%Unchanged
Harbor Advisors LLC10,000$50.2K0.01%00.0%Unchanged
Landscape Capital Management, L.L.C.10,016$50.3K0.00%+10,016New
Simplex Trading, LLC10,268$51.5K0.00%+10,268New
Mercer Global Advisors Inc10,386$52.1K0.00%+10,386New
Mount Vernon Associates Inc10,500$53.0K0.04%+10,500New
Cambridge Investment Research Advisors, Inc.10,700$54.0K0.00%00.0%Unchanged
Cygnus Capital Advisors, LLC12,000$60.0K0.04%+12,000New
Prelude Capital Management, LLC12,000$60.2K0.00%+12,000New
JustInvest LLC12,901$64.8K0.00%−343−2.6%Reduced
Forefront Analytics, LLC13,226$66.4K0.06%−13,801−51.1%Reduced
Group One Trading, L.P.14,184$71.2K0.00%−21,381−60.1%Reduced
Victory Capital Management Inc14,757$74.1K0.00%+3,736+33.9%Added
Cerity Partners LLC14,801$74.3K0.00%+14,801New
VisionPoint Advisory Group, LLC15,000$75.3K0.01%00.0%Unchanged
Coastal Bridge Advisors, LLC17,000$85.3K0.01%00.0%Unchanged
Scientech Research LLC17,216$86.4K0.05%+17,216New
Canada Pension Plan Investment Board17,600$88.4K0.00%+17,600New
Caitong International Asset Management Co., Ltd19,197$96.4K0.02%+19,197New
Voya Investment Management LLC19,318$97.0K0.00%00.0%Unchanged
CI Private Wealth, LLC19,693$98.9K0.00%+28+0.1%Added
Wealth Enhancement Advisory Services, LLC19,553$99.7K0.00%+2,348+13.6%Added
Lido Advisors, LLC34,952$106.6K0.00%00.0%Unchanged
Citigroup Inc23,640$118.7K0.00%+16,812+246.2%Added
Creative Planning24,004$120.5K0.00%+8,553+55.4%Added
ProShare Advisors LLC24,698$124.0K0.00%+4,410+21.7%Added
Raymond James Financial Inc24,869$124.8K0.00%+4,869+24.3%Added
HSBC Holdings PLC25,651$130.2K0.00%−70−0.3%Reduced
SG Americas Securities, LLC28,071$141.0K0.00%+17,074+155.3%Added
Police & Firemen's Retirement System of New Jersey28,105$141.1K0.00%00.0%Unchanged
Axq Capital, LP29,108$146.1K0.03%+1,241+4.5%Added
New York State Common Retirement Fund29,568$148.4K0.00%−4,911−14.2%Reduced
CWM, LLC30,297$152.0K0.00%+6,809+29.0%Added
Mariner, LLC31,335$157.4K0.00%+31,335New
Captrust Financial Advisors31,585$158.6K0.00%+31,585New
Comerica Bank32,357$162.4K0.00%00.0%Unchanged
Landing Point Financial Group, LLC34,900$175.2K0.09%+34,900New
China Universal Asset Management Co., Ltd.36,084$181.1K0.01%+823+2.3%Added
Pale Fire Capital SE38,600$193.8K0.02%+38,600New
MetLife Investment Management39,059$196.1K0.00%−5,573−12.5%Reduced
Citizens Financial Group Inc40,000$200.8K0.00%00.0%Unchanged
Intech Investment Management LLC42,524$213.5K0.00%+15,848+59.4%Added
EntryPoint Capital, LLC42,774$214.7K0.08%+22,803+114.2%Added
Allegheny Financial Group LTD42,900$215.4K0.03%00.0%Unchanged
TD Asset Management Inc46,848$235.2K0.00%00.0%Unchanged
ADAR1 Capital Management, LLC48,000$241.0K0.02%+48,000New
Quadrature Capital Ltd48,573$243.8K0.00%+48,573New
Profund Advisors LLC53,008$266.1K0.01%+53,008New
Winton Group Ltd53,400$268.1K0.01%+53,400New
Virtus Investment Advisers, Inc.53,527$268.7K0.07%+11,540+27.5%Added
JPMorgan Chase & Co53,729$269.7K0.00%+6,843+14.6%Added
Mirae Asset Global ETFs Holdings Ltd.54,763$275.1K0.00%+9,784+21.8%Added
SEI Investments Co58,259$292.5K0.00%+58,259New
BNP Paribas Arbitrage, SA61,572$309.1K0.00%+41,833+211.9%Added
Boothbay Fund Management, LLC64,069$321.6K0.01%+64,069New
Quarry LP75,000$376.5K0.06%−35,000−31.8%Reduced
Persistent Asset Partners Ltd93,657$470.2K0.23%+93,657New
J. Safra Sarasin Holding AG117,768$591.2K0.01%−105,453−47.2%Reduced
DnB Asset Management AS118,324$594.0K0.00%+33,801+40.0%Added
Caption Management, LLC119,491$599.8K0.03%+119,491New
Jump Financial, LLC122,858$616.7K0.01%+122,858New
Brevan Howard Capital Management LP123,753$621.2K0.01%+29,199+30.9%Added
Rhumbline Advisers126,463$634.8K0.00%−6,140−4.6%Reduced
Manufacturers Life Insurance Company, The130,102$655.1K0.00%−2,571−1.9%Reduced
Bridgeway Capital Management, LLC137,800$691.8K0.01%00.0%Unchanged
Alliancebernstein L.P.140,740$706.5K0.00%00.0%Unchanged
Rafferty Asset Management, LLC141,644$711.1K0.00%+141,644New
Advisor Group Holdings, Inc.147,375$739.8K0.00%00.0%Unchanged