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Annexon, Inc.

ANNX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001528115

In the last 90 days, Annexon, Inc. insiders filed 1 open-market purchase and 0 sales; 216 institutions reported holding it in 13F filings for Q2 2026, worth $1.02B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Annexon, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
144
+16 vs. Q2 2025
Shares held
101.4M
+1.69M (+1.7%) vs. Q2 2025
Total value
$309.2M
+$70.5M (+29.5%) vs. Q2 2025
New holders
33
51 more added
Sold out
17
36 more reduced

1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANNX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 144 institutions
Q1 2021: 72 institutionsQ2 2021: 74 institutionsQ3 2021: 82 institutionsQ4 2021: 97 institutionsQ1 2022: 100 institutionsQ2 2022: 78 institutionsQ3 2022: 72 institutionsQ4 2022: 84 institutionsQ1 2023: 100 institutionsQ2 2023: 95 institutionsQ3 2023: 93 institutionsQ4 2023: 99 institutionsQ1 2024: 127 institutionsQ2 2024: 140 institutionsQ3 2024: 142 institutionsQ4 2024: 153 institutionsQ1 2025: 148 institutionsQ2 2025: 129 institutionsQ3 2025: 144 institutionsQ4 2025: 168 institutionsQ1 2026: 217 institutionsQ2 2026: 216 institutions
Value heldQ3 2025: $309.2M
Q1 2021: $1.04BQ2 2021: $873.7MQ3 2021: $708.6MQ4 2021: $445.7MQ1 2022: $105.9MQ2 2022: $144.9MQ3 2022: $292.3MQ4 2022: $243.3MQ1 2023: $207.6MQ2 2023: $190.0MQ3 2023: $126.0MQ4 2023: $365.7MQ1 2024: $679.4MQ2 2024: $526.9MQ3 2024: $651.8MQ4 2024: $574.6MQ1 2025: $192.1MQ2 2025: $238.7MQ3 2025: $309.2MQ4 2025: $687.2MQ1 2026: $863.7MQ2 2026: $1.02B
Institutions holding ANNX and their total value by quarter
QuarterHoldersValue
Q2 2026216$1.02B
Q1 2026217$863.7M
Q4 2025168$687.2M
Q3 2025144$309.2M
Q2 2025129$238.7M
Q1 2025148$192.1M
Q4 2024153$574.6M
Q3 2024142$651.8M
Q2 2024140$526.9M
Q1 2024127$679.4M
Q4 202399$365.7M
Q3 202393$126.0M
Q2 202395$190.0M
Q1 2023100$207.6M
Q4 202284$243.3M
Q3 202272$292.3M
Q2 202278$144.9M
Q1 2022100$105.9M
Q4 202197$445.7M
Q3 202182$708.6M
Q2 202174$873.7M
Q1 202172$1.04B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Annexon, Inc.; share changes are against Q2 2025.

Institutions holding ANNX in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
UBS Group AG346,139$1.06M0.00%+21,017+6.5%Added
Susquehanna Portfolio Strategies, LLC353,744$1.08M0.02%+146,029+70.3%Added
Parkman Healthcare Partners LLC405,953$1.24M0.14%+1,759+0.4%Added
Wells Fargo & Company409,477$1.25M0.00%+32,503+8.6%Added
Hennion & Walsh Asset Management, Inc.475,929$1.45M0.05%−8,704−1.8%Reduced
Board of Trustees of The Leland Stanford Junior University482,550$1.47M0.17%00.0%Unchanged
Price T Rowe Associates Inc484,775$1.48M0.00%−23,328−4.6%Reduced
Acadian Asset Management LLC532,363$1.62M0.00%+63,154+13.5%Added
Qube Research & Technologies Ltd572,644$1.75M0.00%+147,924+34.8%Added
AQR Capital Management LLC574,123$1.75M0.00%+242,092+72.9%Added
Deerfield Management Company, L.P. (Series C)583,913$1.78M0.03%00.0%Unchanged
Kennedy Capital Management, Inc.640,460$1.95M0.04%−215,113−25.1%Reduced
Nuveen, LLC682,558$2.08M0.00%+426,640+166.7%Added
Renaissance Technologies LLC753,579$2.30M0.00%−24,321−3.1%Reduced
Dimensional Fund Advisors LP766,955$2.34M0.00%−122,908−13.8%Reduced
Northern Trust Corp787,708$2.40M0.00%+44,484+6.0%Added
Charles Schwab Investment Management Inc790,250$2.41M0.00%+61,861+8.5%Added
Rhenman & Partners Asset Management AB823,000$2.51M0.28%+363,000+78.9%Added
Sirios Capital Management L P970,200$2.96M0.39%−19,377−2.0%Reduced
Massachusetts Financial Services Co980,285$2.99M0.00%−7,228−0.7%Reduced
Mutual of America Capital Management LLC1,066,932$3.25M0.03%−12,029−1.1%Reduced
J. Goldman & Co LP1,107,001$3.38M0.13%+1,107,001New
Bank of America Corp1,294,302$3.95M0.00%−158,493−10.9%Reduced
Balyasny Asset Management LLC1,297,260$3.96M0.01%+1,297,260New
Adage Capital Partners GP, L.L.C.1,500,000$4.58M0.01%+1,500,000New
Deutsche Bank AG1,504,349$4.59M0.00%+992,901+194.1%Added
Sphera Funds Management Ltd.1,794,387$5.47M1.30%+30,000+1.7%Added
State Street Corp2,050,308$6.25M0.00%+69,324+3.5%Added
Polygon Management Ltd.2,112,455$6.44M0.94%−697,545−24.8%Reduced
Ameriprise Financial Inc2,192,354$6.69M0.00%+26,176+1.2%Added
Goldman Sachs Group Inc2,406,432$7.34M0.00%+775,783+47.6%Added
Geode Capital Management, LLC2,436,944$7.43M0.00%+152,171+6.7%Added
Candriam Luxembourg S.C.A.2,534,230$7.73M0.04%00.0%Unchanged
Opaleye Management Inc.2,600,000$7.93M1.12%+2,600,000New
Woodline Partners LP2,638,275$8.05M0.04%+1,584,566+150.4%Added
Millennium Management LLC2,822,823$8.61M0.01%+308,689+12.3%Added
Morgan Stanley3,029,848$9.24M0.00%+2,197,308+263.9%Added
Bellevue Group AG5,157,290$15.7M0.33%00.0%Unchanged
Bain Capital Life Sciences Investors, LLC5,249,069$16.0M1.06%00.0%Unchanged
Vanguard Group Inc5,835,112$17.8M0.00%+469,073+8.7%Added
Redmile Group, LLC6,300,644$19.2M1.87%00.0%Unchanged
BVF Inc7,000,000$21.4M0.87%00.0%Unchanged
BlackRock, Inc.7,899,008$24.1M0.00%−63,360−0.8%Reduced
FMR LLC11,081,163$33.8M0.00%−4,614,063−29.4%Reduced
Sio Capital Management, LLC0$00.00%−4,095,764−100.0%Sold out
Logos Global Management LP0$00.00%−2,410,000−100.0%Sold out
Walleye Capital LLC0$00.00%−794,639−100.0%Sold out
UBS Oconnor LLC0$00.00%−492,698−100.0%Sold out
UBS Asset Management Americas Inc0$00.00%−93,500−100.0%Sold out
Natixis0$00.00%−77,100−100.0%Sold out
Virtu Financial LLC0$00.00%−30,597−100.0%Sold out
Marshall Wace, LLP0$00.00%−29,989−100.0%Sold out
Quadrature Capital Ltd0$00.00%−20,515−100.0%Sold out
Driehaus Capital Management LLC0$00.00%−258,314−100.0%Sold out
Los Angeles Capital Management LLC0$00.00%−20,196−100.0%Sold out
State Board of Administration of Florida Retirement System0$00.00%−15,607−100.0%Sold out
Engineers Gate Manager LP0$00.00%−13,401−100.0%Sold out
Point72 Asia (Singapore) Pte. Ltd.0$00.00%−7,111−100.0%Sold out
Simplex Trading, LLC0$00.00%−6,673−100.0%Sold out
Point72 (DIFC) Ltd0$00.00%−1,964−100.0%Sold out
Prestige Wealth Management Group LLC0$00.00%−185−100.0%Sold out
CIBC World Markets Corp––––Not filed