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Annexon, Inc.

ANNX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001528115

In the last 90 days, Annexon, Inc. insiders filed 1 open-market purchase and 0 sales; 216 institutions reported holding it in 13F filings for Q2 2026, worth $1.02B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Annexon, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
144
+16 vs. Q2 2025
Shares held
101.4M
+1.69M (+1.7%) vs. Q2 2025
Total value
$309.2M
+$70.5M (+29.5%) vs. Q2 2025
New holders
33
51 more added
Sold out
17
36 more reduced

1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANNX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 144 institutions
Q1 2021: 72 institutionsQ2 2021: 74 institutionsQ3 2021: 82 institutionsQ4 2021: 97 institutionsQ1 2022: 100 institutionsQ2 2022: 78 institutionsQ3 2022: 72 institutionsQ4 2022: 84 institutionsQ1 2023: 100 institutionsQ2 2023: 95 institutionsQ3 2023: 93 institutionsQ4 2023: 99 institutionsQ1 2024: 127 institutionsQ2 2024: 140 institutionsQ3 2024: 142 institutionsQ4 2024: 153 institutionsQ1 2025: 148 institutionsQ2 2025: 129 institutionsQ3 2025: 144 institutionsQ4 2025: 168 institutionsQ1 2026: 217 institutionsQ2 2026: 216 institutions
Value heldQ3 2025: $309.2M
Q1 2021: $1.04BQ2 2021: $873.7MQ3 2021: $708.6MQ4 2021: $445.7MQ1 2022: $105.9MQ2 2022: $144.9MQ3 2022: $292.3MQ4 2022: $243.3MQ1 2023: $207.6MQ2 2023: $190.0MQ3 2023: $126.0MQ4 2023: $365.7MQ1 2024: $679.4MQ2 2024: $526.9MQ3 2024: $651.8MQ4 2024: $574.6MQ1 2025: $192.1MQ2 2025: $238.7MQ3 2025: $309.2MQ4 2025: $687.2MQ1 2026: $863.7MQ2 2026: $1.02B
Institutions holding ANNX and their total value by quarter
QuarterHoldersValue
Q2 2026216$1.02B
Q1 2026217$863.7M
Q4 2025168$687.2M
Q3 2025144$309.2M
Q2 2025129$238.7M
Q1 2025148$192.1M
Q4 2024153$574.6M
Q3 2024142$651.8M
Q2 2024140$526.9M
Q1 2024127$679.4M
Q4 202399$365.7M
Q3 202393$126.0M
Q2 202395$190.0M
Q1 2023100$207.6M
Q4 202284$243.3M
Q3 202272$292.3M
Q2 202278$144.9M
Q1 2022100$105.9M
Q4 202197$445.7M
Q3 202182$708.6M
Q2 202174$873.7M
Q1 202172$1.04B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Annexon, Inc.; share changes are against Q2 2025.

Institutions holding ANNX in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Farther Finance Advisors, LLC1$30.00%00.0%Unchanged
Advisory Services Network, LLC23$700.00%+23New
SBI Securities Co., Ltd.26$790.00%−4−13.3%Reduced
True Wealth Design, LLC55$1680.00%+55New
Sunbelt Securities, Inc.87$2650.00%+87New
Allworth Financial LP152$4640.00%+107+237.8%Added
Rothschild Investment LLC165$5030.00%00.0%Unchanged
UMA Financial Services, Inc.269$8210.00%+269New
Essential Partners LLC293$8940.00%+91+45.0%Added
EverSource Wealth Advisors, LLC296$9030.00%+44+17.5%Added
HighMark Wealth Management LLC300$9150.00%00.0%Unchanged
Daiwa Securities Group Inc.352$1.00K0.00%00.0%Unchanged
IFP Advisors, Inc350$1.07K0.00%+242+224.1%Added
Clearstead Advisors, LLC355$1.08K0.00%+355New
The PNC Financial Services Group, Inc.1,123$3.42K0.00%+89+8.6%Added
Optiver Holding B.V.1,304$3.98K0.00%+1,304New
GF Fund Management Co. Ltd.2,364$7.21K0.00%−365−13.4%Reduced
Nisa Investment Advisors, LLC2,613$7.97K0.00%−94−3.5%Reduced
Amalgamated Bank3,370$10.0K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.4,248$13.0K0.00%+10+0.2%Added
California State Teachers Retirement System5,995$18.3K0.00%+5,995New
Geneos Wealth Management Inc.6,000$18.3K0.00%+6,000New
Tower Research Capital LLC (TRC)6,096$18.6K0.00%−9,462−60.8%Reduced
SRS Capital Advisors, Inc.6,530$19.9K0.00%+6,530New
Sterling Capital Management LLC6,607$20.2K0.00%+3,849+139.6%Added
Citigroup Inc6,828$20.8K0.00%−30,968−81.9%Reduced
Legal & General Group Plc8,476$25.9K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.9,689$29.6K0.00%00.0%Unchanged
Harbor Advisors LLC10,000$30.5K0.00%00.0%Unchanged
CIBC Bancorp USA Inc.10,208$31.1K0.00%+10,208New
Cambridge Investment Research Advisors, Inc.10,700$33.0K0.00%00.0%Unchanged
Victory Capital Management Inc11,021$33.6K0.00%−370−3.2%Reduced
SG Americas Securities, LLC10,997$34.0K0.00%+10,997New
Prudential Financial Inc11,670$35.6K0.00%00.0%Unchanged
49 Wealth Management, LLC12,083$36.9K0.00%00.0%Unchanged
JustInvest LLC13,244$40.4K0.00%+960+7.8%Added
VisionPoint Advisory Group, LLC15,000$45.8K0.01%+15,000New
Creative Planning15,451$47.1K0.00%+15,451New
Coastal Bridge Advisors, LLC17,000$51.9K0.00%00.0%Unchanged
Wealth Enhancement Advisory Services, LLC17,205$52.8K0.00%+17,205New
Russell Investments Group, Ltd.18,220$55.6K0.00%+18,220New
Voya Investment Management LLC19,318$58.9K0.00%−8,137−29.6%Reduced
CI Private Wealth, LLC19,665$60.0K0.00%+19,665New
BNP Paribas Arbitrage, SA19,739$60.2K0.00%+9,760+97.8%Added
EntryPoint Capital, LLC19,971$60.9K0.02%+19,971New
Raymond James Financial Inc20,000$61.0K0.00%+20,000New
ProShare Advisors LLC20,288$61.9K0.00%−3,444−14.5%Reduced
Matauro, LLC20,572$62.7K0.01%+9,488+85.6%Added
Jacobs Levy Equity Management, Inc22,589$68.9K0.00%+22,589New
Cubist Systematic Strategies, LLC22,771$69.5K0.00%+22,771New
CWM, LLC23,488$72.0K0.00%+5,754+32.4%Added
Two Sigma Advisers, LP23,800$72.6K0.00%+23,800New
HSBC Holdings PLC25,721$78.1K0.00%−4,134−13.8%Reduced
Intech Investment Management LLC26,676$81.4K0.00%−26,023−49.4%Reduced
Forefront Analytics, LLC27,027$82.4K0.08%−548−2.0%Reduced
Forefront Wealth Partners, LLC27,027$82.4K0.02%+27,027New
Axq Capital, LP27,867$85.0K0.03%+27,867New
Police & Firemen's Retirement System of New Jersey28,105$85.7K0.00%+7,518+36.5%Added
Atom Investors LP30,453$92.9K0.01%+30,453New
Comerica Bank32,357$98.7K0.00%+6,750+26.4%Added
New York State Common Retirement Fund34,479$105.2K0.00%00.0%Unchanged
Lido Advisors, LLC34,952$106.6K0.00%−48−0.1%Reduced
China Universal Asset Management Co., Ltd.35,261$107.5K0.01%+13,225+60.0%Added
Group One Trading, L.P.35,565$108.5K0.00%+35,565New
Citizens Financial Group Inc40,000$122.0K0.00%+5,000+14.3%Added
Virtus Investment Advisers, Inc.41,987$128.1K0.04%+7,289+21.0%Added
Allegheny Financial Group LTD42,900$130.8K0.02%00.0%Unchanged
MetLife Investment Management44,632$136.1K0.00%−14,390−24.4%Reduced
Mirae Asset Global ETFs Holdings Ltd.44,979$137.2K0.00%−7,426−14.2%Reduced
TD Asset Management Inc46,848$142.9K0.00%00.0%Unchanged
JPMorgan Chase & Co46,886$143.0K0.00%−5,933−11.2%Reduced
Alps Advisors Inc47,879$146.0K0.00%−11,322−19.1%Reduced
Cinctive Capital Management LP65,466$199.7K0.01%−70,000−51.7%Reduced
HRT Financial LP84,582$257.0K0.00%+84,582New
DnB Asset Management AS84,523$257.8K0.00%−15,051−15.1%Reduced
Point72 Asset Management, L.P.90,049$274.6K0.00%+90,049New
Brevan Howard Capital Management LP94,554$288.4K0.00%+41,271+77.5%Added
Quarry LP110,000$335.5K0.08%+66,867+155.0%Added
Park Avenue Securities LLC113,068$345.0K0.00%00.0%Unchanged
Rhumbline Advisers132,603$404.4K0.00%−4,933−3.6%Reduced
Manufacturers Life Insurance Company, The132,673$404.7K0.00%−1,362−1.0%Reduced
Bridgeway Capital Management, LLC137,800$420.3K0.01%+40,000+40.9%Added
Alliancebernstein L.P.140,740$429.3K0.00%00.0%Unchanged
XTX Topco Ltd147,840$450.9K0.02%+147,840New
Barclays PLC147,930$451.2K0.00%−29,698−16.7%Reduced
Ieq Capital, LLC150,322$458.5K0.00%+14,525+10.7%Added
Advisor Group Holdings, Inc.147,375$458.8K0.00%+67,000+83.4%Added
Susquehanna International Group, LLP151,250$461.3K0.00%−115,562−43.3%Reduced
Citadel Advisors LLC167,500$510.9K0.00%+154,233+1,162.5%Added
Invesco Ltd.201,945$615.9K0.00%+51,531+34.3%Added
Schonfeld Strategic Advisors LLC212,219$647.3K0.00%−53,831−20.2%Reduced
Jane Street Group, LLC219,494$669.5K0.00%+73,625+50.5%Added
J. Safra Sarasin Holding AG223,221$680.8K0.01%−158,220−41.5%Reduced
American Century Companies Inc236,736$722.0K0.00%+25,541+12.1%Added
SummitTX Capital, L.P.241,991$738.1K0.03%+241,991New
ExodusPoint Capital Management, LP243,755$743.5K0.01%+182,064+295.1%Added
Two Sigma Investments, LP279,134$851.4K0.00%+77,974+38.8%Added
Royal Bank of Canada285,848$871.0K0.00%+40,649+16.6%Added
Point72 Europe (London) LLP302,861$923.7K0.05%+96,063+46.5%Added
Bank of New York Mellon Corp308,188$940.0K0.00%+7,140+2.4%Added