Annexon, Inc.

ANNX

Exchange: Nasdaq
Industry: Pharmaceutical Preparations
SEC CIK: 0001528115

SEC filings (opens in a new tab)

In the last 90 days, Annexon, Inc. insiders filed 1 open-market purchase and 0 sales; 216 institutions reported holding it in 13F filings for Q2 2026, worth $1.02B in total; no superinvestor holds it.

Q3 2025 vs. Q2 2025

How the institutions holding Annexon, Inc. changed between Q2 2025 and Q3 2025.

All holders in Q3 2025 All holders in Q2 2025

13F holders of ANNX: Q2 2025 compared with Q3 2025
Measure	Q2 2025	Of which not filed for Q3 2025	Q3 2025	Change
Holders	129	1	144	+16
Shares	99.7M	11.8K	101.4M	+1.69M (+1.7%)
Value	$238.7M	$28.3K	$309.2M	+$70.5M (+29.5%)

1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (33)

Institutions that held Annexon, Inc. at the end of Q3 2025 but not at the end of Q2 2025.

Institutions new to ANNX in Q3 2025
Institution	Shares	Value	% of portfolio
Opaleye Management Inc.	2,600,000	$7.93M	1.12%
Adage Capital Partners GP, L.L.C.	1,500,000	$4.58M	0.01%
Balyasny Asset Management LLC	1,297,260	$3.96M	0.01%
J. Goldman & Co LP	1,107,001	$3.38M	0.13%
SummitTX Capital, L.P.	241,991	$738.1K	0.03%
XTX Topco Ltd	147,840	$450.9K	0.02%
Point72 Asset Management, L.P.	90,049	$274.6K	0.00%
HRT Financial LP	84,582	$257.0K	0.00%
Group One Trading, L.P.	35,565	$108.5K	0.00%
Atom Investors LP	30,453	$92.9K	0.01%
Axq Capital, LP	27,867	$85.0K	0.03%
Forefront Wealth Partners, LLC	27,027	$82.4K	0.02%
Two Sigma Advisers, LP	23,800	$72.6K	0.00%
Cubist Systematic Strategies, LLC	22,771	$69.5K	0.00%
Jacobs Levy Equity Management, Inc	22,589	$68.9K	0.00%
Raymond James Financial Inc	20,000	$61.0K	0.00%
EntryPoint Capital, LLC	19,971	$60.9K	0.02%
CI Private Wealth, LLC	19,665	$60.0K	0.00%
Russell Investments Group, Ltd.	18,220	$55.6K	0.00%
Wealth Enhancement Advisory Services, LLC	17,205	$52.8K	0.00%
Creative Planning	15,451	$47.1K	0.00%
VisionPoint Advisory Group, LLC	15,000	$45.8K	0.01%
SG Americas Securities, LLC	10,997	$34.0K	0.00%
CIBC Bancorp USA Inc.	10,208	$31.1K	0.00%
SRS Capital Advisors, Inc.	6,530	$19.9K	0.00%
Geneos Wealth Management Inc.	6,000	$18.3K	0.00%
California State Teachers Retirement System	5,995	$18.3K	0.00%
Optiver Holding B.V.	1,304	$3.98K	0.00%
Clearstead Advisors, LLC	355	$1.08K	0.00%
UMA Financial Services, Inc.	269	$821	0.00%
Sunbelt Securities, Inc.	87	$265	0.00%
True Wealth Design, LLC	55	$168	0.00%
Advisory Services Network, LLC	23	$70	0.00%

Sold out (17)

Institutions that held Annexon, Inc. at the end of Q2 2025 and filed for Q3 2025 without it.

Institutions that sold out of ANNX in Q3 2025
Institution	Shares, Q2 2025	Value, Q2 2025
Sio Capital Management, LLC	4,095,764	$9.83M
Logos Global Management LP	2,410,000	$5.78M
Walleye Capital LLC	794,639	$1.91M
UBS Oconnor LLC	492,698	$1.18M
UBS Asset Management Americas Inc	93,500	$224.4K
Natixis	77,100	$185.0K
Virtu Financial LLC	30,597	$73.0K
Marshall Wace, LLP	29,989	$72.0K
Quadrature Capital Ltd	20,515	$49.1K
Driehaus Capital Management LLC	258,314	$48.6K
Los Angeles Capital Management LLC	20,196	$48.5K
State Board of Administration of Florida Retirement System	15,607	$37.5K
Engineers Gate Manager LP	13,401	$32.2K
Point72 Asia (Singapore) Pte. Ltd.	7,111	$17.1K
Simplex Trading, LLC	6,673	$16.0K
Point72 (DIFC) Ltd	1,964	$4.71K
Prestige Wealth Management Group LLC	185	$444

Not filed for Q3 2025 yet (1)

Institutions that held Annexon, Inc. at the end of Q2 2025 and haven't filed a 13F for Q3 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding ANNX in Q2 2025 that haven't filed for Q3 2025
Institution	Shares, Q2 2025	Value, Q2 2025
CIBC World Markets Corp	11,799	$28.3K