Anaptysbio, Inc
ANAB- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001370053
No open-market purchases or sales by Anaptysbio, Inc insiders were filed in the last 90 days; 213 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Anaptysbio, Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 179
- +13 vs. Q3 2025
- Shares held
- 29.4M
- −2.32M (−7.3%) vs. Q3 2025
- Total value
- $1.42B
- +$442.7M (+45.2%) vs. Q3 2025
- New holders
- 37
- 51 more added
- Sold out
- 24
- 64 more reduced
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ANAB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 213 | $2.03B |
| Q1 2026 | 208 | $1.55B |
| Q4 2025 | 179 | $1.42B |
| Q3 2025 | 166 | $980.2M |
| Q2 2025 | 148 | $816.2M |
| Q1 2025 | 153 | $742.8M |
| Q4 2024 | 136 | $468.9M |
| Q3 2024 | 160 | $1.13B |
| Q2 2024 | 135 | $746.6M |
| Q1 2024 | 133 | $658.1M |
| Q4 2023 | 119 | $646.4M |
| Q3 2023 | 116 | $544.5M |
| Q2 2023 | 116 | $614.9M |
| Q1 2023 | 113 | $675.4M |
| Q4 2022 | 118 | $1.02B |
| Q3 2022 | 114 | $830.6M |
| Q2 2022 | 124 | $632.6M |
| Q1 2022 | 131 | $735.4M |
| Q4 2021 | 136 | $964.4M |
| Q3 2021 | 127 | $748.8M |
| Q2 2021 | 122 | $720.6M |
| Q1 2021 | 122 | $628.6M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Anaptysbio, Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Wells Fargo & Company | 22,207 | $1.08M | 0.00% | +8,464+61.6% | Added |
| Tema ETFs LLC | 22,560 | $1.09M | 0.08% | +11,585+105.6% | Added |
| NEOS Investment Management LLC | 22,895 | $1.11M | 0.01% | +11,920+108.6% | Added |
| Mackenzie Financial Corp | 24,228 | $1.17M | 0.00% | +24,228 | New |
| Quadrature Capital Ltd | 24,280 | $1.18M | 0.01% | +24,280 | New |
| Schonfeld Strategic Advisors LLC | 24,431 | $1.18M | 0.01% | +24,431 | New |
| Rhumbline Advisers | 25,032 | $1.21M | 0.00% | −4,212−14.4% | Reduced |
| Headlands Technologies LLC | 25,278 | $1.23M | 0.10% | +25,278 | New |
| Campbell & CO Investment Adviser LLC | 25,368 | $1.23M | 0.06% | +7,087+38.8% | Added |
| Price T Rowe Associates Inc | 26,005 | $1.26M | 0.00% | −273,306−91.3% | Reduced |
| AQR Capital Management LLC | 26,309 | $1.28M | 0.00% | +135+0.5% | Added |
| FMR LLC | 27,108 | $1.31M | 0.00% | −26,054−49.0% | Reduced |
| Swiss National Bank | 27,600 | $1.34M | 0.00% | −800−2.8% | Reduced |
| Advisor Group Holdings, Inc. | 27,737 | $1.34M | 0.00% | +25,921+1,427.4% | Added |
| UBS Asset Management Americas Inc | 30,508 | $1.48M | 0.00% | −2,763−8.3% | Reduced |
| Alliancebernstein L.P. | 30,520 | $1.48M | 0.00% | 00.0% | Unchanged |
| Y-Intercept (Hong Kong) Ltd | 33,101 | $1.60M | 0.04% | +33,101 | New |
| DCF Advisers, LLC | 35,250 | $1.71M | 0.56% | −12,750−26.6% | Reduced |
| Rafferty Asset Management, LLC | 35,310 | $1.71M | 0.01% | +5,225+17.4% | Added |
| Susquehanna Portfolio Strategies, LLC | 35,948 | $1.74M | 0.03% | +500+1.4% | Added |
| XTX Topco Ltd | 38,637 | $1.87M | 0.05% | +20,526+113.3% | Added |
| Credit Agricole S A | 40,000 | $1.94M | 0.01% | +40,000 | New |
| PDT Partners, LLC | 43,001 | $2.08M | 0.14% | 00.0% | Unchanged |
| Bleakley Financial Group, LLC | 43,547 | $2.11M | 0.04% | +3,566+8.9% | Added |
| Moody Aldrich Partners LLC | 47,601 | $2.31M | 0.43% | −2,281−4.6% | Reduced |
| Jacobs Levy Equity Management, Inc | 55,088 | $2.67M | 0.01% | −323,364−85.4% | Reduced |
| Bank of New York Mellon Corp | 55,345 | $2.68M | 0.00% | −1,685−3.0% | Reduced |
| Penserra Capital Management LLC | 56,352 | $2.73M | 0.03% | +56,352 | New |
| Fisher Asset Management, LLC | 56,564 | $2.74M | 0.00% | −2,314−3.9% | Reduced |
| Trexquant Investment LP | 58,809 | $2.85M | 0.03% | −52,969−47.4% | Reduced |
| Barclays PLC | 59,654 | $2.89M | 0.00% | −3,798−6.0% | Reduced |
| Wellington Management Group LLP | 61,187 | $2.97M | 0.00% | −5,544−8.3% | Reduced |
| UBS Group AG | 70,032 | $3.40M | 0.00% | −5,230−6.9% | Reduced |
| HRT Financial LP | 70,130 | $3.40M | 0.01% | +45,105+180.2% | Added |
| Citigroup Inc | 73,453 | $3.56M | 0.00% | +2,919+4.1% | Added |
| Renaissance Technologies LLC | 76,300 | $3.70M | 0.01% | −47,000−38.1% | Reduced |
| ExodusPoint Capital Management, LP | 83,313 | $4.04M | 0.04% | +56,813+214.4% | Added |
| Jane Street Group, LLC | 84,447 | $4.09M | 0.00% | −96,665−53.4% | Reduced |
| Nomura Asset Management International Inc. | 93,732 | $4.54M | 0.01% | +93,732 | New |
| HighMark Wealth Management LLC | 94,050 | $4.56M | 1.86% | −41,000−30.4% | Reduced |
| Qube Research & Technologies Ltd | 108,965 | $5.28M | 0.01% | +108,965 | New |
| Citadel Advisors LLC | 109,483 | $5.31M | 0.00% | +83,003+313.5% | Added |
| Victory Capital Management Inc | 110,583 | $5.36M | 0.00% | −93,472−45.8% | Reduced |
| Jump Financial, LLC | 120,217 | $5.83M | 0.07% | +38,140+46.5% | Added |
| Eversept Partners, LP | 120,927 | $5.86M | 0.33% | +120,927 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 122,476 | $5.94M | 0.02% | +122,476 | New |
| Invesco Ltd. | 124,006 | $6.01M | 0.00% | +81,625+192.6% | Added |
| Granahan Investment Management Inc | 125,855 | $6.10M | 0.26% | −21,918−14.8% | Reduced |
| Bank of America Corp | 130,767 | $6.34M | 0.00% | +3,526+2.8% | Added |
| Soleus Capital Management, L.P. | 135,000 | $6.54M | 0.28% | −491,040−78.4% | Reduced |
| Squarepoint Ops LLC | 160,731 | $7.79M | 0.02% | +92,717+136.3% | Added |
| BNP Paribas Arbitrage, SA | 164,823 | $7.99M | 0.01% | +59,160+56.0% | Added |
| Northern Trust Corp | 181,884 | $8.82M | 0.00% | −13,679−7.0% | Reduced |
| Charles Schwab Investment Management Inc | 198,660 | $9.63M | 0.00% | −7,781−3.8% | Reduced |
| Ensign Peak Advisors, Inc | 215,454 | $10.4M | 0.02% | 00.0% | Unchanged |
| Voloridge Investment Management, LLC | 229,137 | $11.1M | 0.04% | +219,816+2,358.3% | Added |
| Two Sigma Investments, LP | 256,635 | $12.4M | 0.02% | +215+0.1% | Added |
| Sofinnova Investments, Inc. | 287,690 | $13.9M | 0.60% | +33,422+13.1% | Added |
| Federated Hermes, Inc. | 299,416 | $14.5M | 0.02% | +106,089+54.9% | Added |
| Nuveen, LLC | 316,685 | $15.4M | 0.00% | −22,586−6.7% | Reduced |
| Two Sigma Advisers, LP | 356,700 | $17.3M | 0.03% | −17,000−4.5% | Reduced |
| Goldman Sachs Group Inc | 398,914 | $19.3M | 0.00% | +69,094+20.9% | Added |
| Affinity Asset Advisors, LLC | 444,692 | $21.6M | 1.55% | +444,692 | New |
| Geode Capital Management, LLC | 469,494 | $22.8M | 0.00% | −4,132−0.9% | Reduced |
| Woodline Partners LP | 501,023 | $24.3M | 0.09% | 00.0% | Unchanged |
| Arrowstreet Capital, Limited Partnership | 559,744 | $27.1M | 0.02% | +189,286+51.1% | Added |
| First Light Asset Management, LLC | 646,238 | $31.3M | 2.40% | −343,923−34.7% | Reduced |
| 683 Capital Management, LLC | 648,093 | $31.4M | 2.61% | +101,093+18.5% | Added |
| D. E. Shaw & Co., Inc. | 670,288 | $32.5M | 0.02% | +320,928+91.9% | Added |
| Palo Alto Investors LP | 690,032 | $33.5M | 4.66% | +16,512+2.5% | Added |
| Millennium Management LLC | 813,571 | $39.4M | 0.03% | −705,659−46.4% | Reduced |
| Sanofi | 821,917 | $39.8M | 12.84% | 00.0% | Unchanged |
| Morgan Stanley | 1,034,562 | $50.2M | 0.00% | −521,696−33.5% | Reduced |
| State Street Corp | 1,053,474 | $51.1M | 0.00% | +180,042+20.6% | Added |
| Tang Capital Management LLC | 1,332,087 | $64.6M | 3.19% | −1,552−0.1% | Reduced |
| Vanguard Group Inc | 1,544,037 | $74.9M | 0.00% | +67,048+4.5% | Added |
| BlackRock, Inc. | 1,734,430 | $84.1M | 0.00% | +12,106+0.7% | Added |
| Point72 Asset Management, L.P. | 1,932,890 | $93.7M | 0.15% | −332,638−14.7% | Reduced |
| EcoR1 Capital, LLC | 7,880,094 | $382.0M | 17.51% | 00.0% | Unchanged |
| Assenagon Asset Management S.A. | 0 | $0 | 0.00% | −839,934−100.0% | Sold out |
| Franklin Resources Inc | 0 | $0 | 0.00% | −47,332−100.0% | Sold out |
| Sectoral Asset Management Inc | 0 | $0 | 0.00% | −194,485−100.0% | Sold out |
| Skandinaviska Enskilda Banken AB (publ) | 0 | $0 | 0.00% | −145,191−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −144,604−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −93,732−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −56,422−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −54,416−100.0% | Sold out |
| Ikarian Capital, LLC | 0 | $0 | 0.00% | −48,410−100.0% | Sold out |
| Boothbay Fund Management, LLC | 0 | $0 | 0.00% | −27,402−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −25,299−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −15,531−100.0% | Sold out |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −15,320−100.0% | Sold out |
| Alps Advisors Inc | 0 | $0 | 0.00% | −13,335−100.0% | Sold out |
| Man Group plc | 0 | $0 | 0.00% | −12,859−100.0% | Sold out |
| DRW Securities, LLC | 0 | $0 | 0.00% | −6,629−100.0% | Sold out |
| Diadema Partners LP | 0 | $0 | 0.00% | −3,295−100.0% | Sold out |
| Global Retirement Partners, LLC | 0 | $0 | 0.00% | −1,230−100.0% | Sold out |
| Persistent Asset Partners Ltd | 0 | $0 | 0.00% | −754−100.0% | Sold out |
| Clear Street Markets LLC | 0 | $0 | 0.00% | −170−100.0% | Sold out |
| Principal Securities, Inc. | 0 | $0 | 0.00% | −14−100.0% | Sold out |