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Anaptysbio, Inc

ANAB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001370053

No open-market purchases or sales by Anaptysbio, Inc insiders were filed in the last 90 days; 213 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Anaptysbio, Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
166
+19 vs. Q2 2025
Shares held
31.7M
−4.97M (−13.6%) vs. Q2 2025
Total value
$980.2M
+$166.8M (+20.5%) vs. Q2 2025
New holders
34
44 more added
Sold out
15
59 more reduced

1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANAB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 166 institutions
Q1 2021: 122 institutionsQ2 2021: 122 institutionsQ3 2021: 127 institutionsQ4 2021: 136 institutionsQ1 2022: 131 institutionsQ2 2022: 124 institutionsQ3 2022: 114 institutionsQ4 2022: 118 institutionsQ1 2023: 113 institutionsQ2 2023: 116 institutionsQ3 2023: 116 institutionsQ4 2023: 119 institutionsQ1 2024: 133 institutionsQ2 2024: 135 institutionsQ3 2024: 160 institutionsQ4 2024: 136 institutionsQ1 2025: 153 institutionsQ2 2025: 148 institutionsQ3 2025: 166 institutionsQ4 2025: 179 institutionsQ1 2026: 208 institutionsQ2 2026: 213 institutions
Value heldQ3 2025: $980.2M
Q1 2021: $628.6MQ2 2021: $720.6MQ3 2021: $748.8MQ4 2021: $964.4MQ1 2022: $735.4MQ2 2022: $632.6MQ3 2022: $830.6MQ4 2022: $1.02BQ1 2023: $675.4MQ2 2023: $614.9MQ3 2023: $544.5MQ4 2023: $646.4MQ1 2024: $658.1MQ2 2024: $746.6MQ3 2024: $1.13BQ4 2024: $468.9MQ1 2025: $742.8MQ2 2025: $816.2MQ3 2025: $980.2MQ4 2025: $1.42BQ1 2026: $1.55BQ2 2026: $2.03B
Institutions holding ANAB and their total value by quarter
QuarterHoldersValue
Q2 2026213$2.03B
Q1 2026208$1.55B
Q4 2025179$1.42B
Q3 2025166$980.2M
Q2 2025148$816.2M
Q1 2025153$742.8M
Q4 2024136$468.9M
Q3 2024160$1.13B
Q2 2024135$746.6M
Q1 2024133$658.1M
Q4 2023119$646.4M
Q3 2023116$544.5M
Q2 2023116$614.9M
Q1 2023113$675.4M
Q4 2022118$1.02B
Q3 2022114$830.6M
Q2 2022124$632.6M
Q1 2022131$735.4M
Q4 2021136$964.4M
Q3 2021127$748.8M
Q2 2021122$720.6M
Q1 2021122$628.6M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Anaptysbio, Inc; share changes are against Q2 2025.

Institutions holding ANAB in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Aquatic Capital Management LLC31,298$958.3K0.02%−34,512−52.4%Reduced
UBS Asset Management Americas Inc33,271$1.02M0.00%−16,534−33.2%Reduced
Russell Investments Group, Ltd.34,032$1.04M0.00%+10,241+43.0%Added
Susquehanna Portfolio Strategies, LLC35,448$1.09M0.02%+2,645+8.1%Added
Gsa Capital Partners LLP37,274$1.14M0.10%−32,525−46.6%Reduced
Bleakley Financial Group, LLC39,981$1.22M0.03%+2,430+6.5%Added
Invesco Ltd.42,381$1.30M0.00%−40,793−49.0%Reduced
PDT Partners, LLC43,001$1.32M0.08%−1,464−3.3%Reduced
DCF Advisers, LLC48,000$1.47M0.56%00.0%Unchanged
Ikarian Capital, LLC48,410$1.48M0.34%+32,748+209.1%Added
Moody Aldrich Partners LLC49,882$1.53M0.29%−10,212−17.0%Reduced
FMR LLC53,162$1.63M0.00%−18,957−26.3%Reduced
Marshall Wace, LLP54,416$1.67M0.00%+54,416New
Walleye Capital LLC56,422$1.73M0.01%+56,422New
Bank of New York Mellon Corp57,030$1.75M0.00%−2,195−3.7%Reduced
Fisher Asset Management, LLC58,878$1.80M0.00%−210.0%Reduced
Barclays PLC63,452$1.94M0.00%−36,547−36.5%Reduced
Panagora Asset Management Inc63,857$1.96M0.01%+30,488+91.4%Added
Wellington Management Group LLP66,731$2.04M0.00%−13,482−16.8%Reduced
Squarepoint Ops LLC68,014$2.08M0.00%−41,374−37.8%Reduced
Citigroup Inc70,534$2.16M0.00%−975,954−93.3%Reduced
UBS Group AG75,262$2.30M0.00%−1,197,237−94.1%Reduced
Jump Financial, LLC82,077$2.51M0.03%+82,077New
Algert Global LLC83,767$2.56M0.04%+83,767New
Macquarie Group Ltd93,732$2.87M0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA105,663$3.24M0.00%+101,964+2,756.5%Added
Trexquant Investment LP111,778$3.42M0.04%−87,464−43.9%Reduced
Renaissance Technologies LLC123,300$3.78M0.00%−139,786−53.1%Reduced
Bank of America Corp127,241$3.90M0.00%−949,558−88.2%Reduced
HighMark Wealth Management LLC135,050$4.42M1.95%−10,500−7.2%Reduced
Susquehanna International Group, LLP144,604$4.43M0.01%−44,723−23.6%Reduced
Skandinaviska Enskilda Banken AB (publ)145,191$4.45M0.02%+111,668+333.1%Added
Granahan Investment Management Inc147,773$4.52M0.19%+16,118+12.2%Added
Jane Street Group, LLC181,112$5.55M0.01%+136,444+305.5%Added
Federated Hermes, Inc.193,327$5.92M0.01%+185,053+2,236.6%Added
Sectoral Asset Management Inc194,485$5.96M3.68%+110,585+131.8%Added
Northern Trust Corp195,563$5.99M0.00%−700−0.4%Reduced
Victory Capital Management Inc204,055$6.25M0.00%−328,030−61.6%Reduced
Charles Schwab Investment Management Inc206,441$6.32M0.00%+49,306+31.4%Added
Ensign Peak Advisors, Inc215,454$6.60M0.01%00.0%Unchanged
Sofinnova Investments, Inc.254,268$7.79M0.48%−778,094−75.4%Reduced
Two Sigma Investments, LP256,420$7.85M0.01%+25,051+10.8%Added
Price T Rowe Associates Inc299,311$9.17M0.00%−373,860−55.5%Reduced
Goldman Sachs Group Inc329,820$10.1M0.00%+49,985+17.9%Added
Nuveen, LLC339,271$10.4M0.00%+15,737+4.9%Added
D. E. Shaw & Co., Inc.349,360$10.7M0.01%+237,011+211.0%Added
Arrowstreet Capital, Limited Partnership370,458$11.3M0.01%+219,648+145.6%Added
Two Sigma Advisers, LP373,700$11.4M0.02%+83,300+28.7%Added
Jacobs Levy Equity Management, Inc378,452$11.6M0.05%+10,005+2.7%Added
Franklin Resources Inc47,332$11.6M0.00%−307,176−86.6%Reduced
Geode Capital Management, LLC473,626$14.5M0.00%+10,268+2.2%Added
Woodline Partners LP501,023$15.3M0.07%00.0%Unchanged
683 Capital Management, LLC547,000$16.7M1.52%+47,000+9.4%Added
Soleus Capital Management, L.P.626,040$19.2M1.02%+305,000+95.0%Added
Palo Alto Investors LP673,520$20.6M3.82%−139,301−17.1%Reduced
Sanofi821,917$25.2M9.67%00.0%Unchanged
Assenagon Asset Management S.A.839,934$25.7M0.04%+822,975+4,852.7%Added
State Street Corp873,432$26.7M0.00%+52,401+6.4%Added
First Light Asset Management, LLC990,161$30.3M2.86%−2,549,432−72.0%Reduced
Tang Capital Management LLC1,333,639$40.8M1.57%+2,760+0.2%Added
Vanguard Group Inc1,476,989$45.2M0.00%−60,561−3.9%Reduced
Millennium Management LLC1,519,230$46.5M0.04%+1,315,688+646.4%Added
Morgan Stanley1,556,258$47.7M0.00%−313,582−16.8%Reduced
BlackRock, Inc.1,722,324$52.7M0.00%−64,610−3.6%Reduced
Point72 Asset Management, L.P.2,265,528$69.4M0.15%−209,346−8.5%Reduced
EcoR1 Capital, LLC7,880,094$241.3M11.60%00.0%Unchanged
Balyasny Asset Management LLC0$00.00%−92,852−100.0%Sold out
UBS Oconnor LLC0$00.00%−38,528−100.0%Sold out
FMB Wealth Management0$00.00%−35,592−100.0%Sold out
SummitTX Capital, L.P.0$00.00%−33,434−100.0%Sold out
Nebula Research & Development LLC0$00.00%−15,533−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−15,200−100.0%Sold out
Exome Asset Management LLC0$00.00%−15,000−100.0%Sold out
Corton Capital Inc.0$00.00%−12,004−100.0%Sold out
Glenmede Investment Management, LP0$00.00%−7,546−100.0%Sold out
SG Americas Securities, LLC0$00.00%−4,921−100.0%Sold out
BIT Capital GmbH0$00.00%−2,706−100.0%Sold out
Skopos Labs, Inc.0$00.00%−1,082−100.0%Sold out
Quarry LP0$00.00%−500−100.0%Sold out
Sherman Asset Management, Inc.0$00.00%−120−100.0%Sold out
Riggs Asset Managment Co. Inc.0$00.00%−69−100.0%Sold out
Camber Capital Management LP––––Not filed