Agios Pharmaceuticals, Inc.
AGIO- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001439222
In the last 90 days, Agios Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 2 sales; 238 institutions reported holding it in 13F filings for Q2 2026, worth $2.45B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Agios Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 238
- +21 vs. Q3 2025
- Shares held
- 61.3M
- −2.05M (−3.2%) vs. Q3 2025
- Total value
- $1.67B
- −$870.9M (−34.3%) vs. Q3 2025
- New holders
- 65
- 79 more added
- Sold out
- 44
- 70 more reduced
4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AGIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 238 | $2.45B |
| Q1 2026 | 234 | $2.12B |
| Q4 2025 | 238 | $1.67B |
| Q3 2025 | 221 | $2.55B |
| Q2 2025 | 216 | $2.05B |
| Q1 2025 | 221 | $1.76B |
| Q4 2024 | 225 | $1.97B |
| Q3 2024 | 208 | $2.58B |
| Q2 2024 | 206 | $2.51B |
| Q1 2024 | 187 | $1.81B |
| Q4 2023 | 170 | $1.33B |
| Q3 2023 | 146 | $1.46B |
| Q2 2023 | 153 | $1.68B |
| Q1 2023 | 165 | $1.36B |
| Q4 2022 | 160 | $1.67B |
| Q3 2022 | 168 | $1.64B |
| Q2 2022 | 157 | $1.31B |
| Q1 2022 | 161 | $1.74B |
| Q4 2021 | 161 | $1.95B |
| Q3 2021 | 165 | $2.81B |
| Q2 2021 | 186 | $3.63B |
| Q1 2021 | 175 | $3.37B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Agios Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Legal & General Group Plc | 328,211 | $8.93M | 0.00% | +5,277+1.6% | Added |
| Marshall Wace, LLP | 353,639 | $9.63M | 0.01% | +126,815+55.9% | Added |
| Qube Research & Technologies Ltd | 378,373 | $10.3M | 0.01% | +378,373 | New |
| Millennium Management LLC | 398,267 | $10.8M | 0.01% | +393,218+7,788.0% | Added |
| Algert Global LLC | 414,218 | $11.3M | 0.18% | +378,448+1,058.0% | Added |
| ArrowMark Colorado Holdings LLC | 466,151 | $12.7M | 0.28% | −213,771−31.4% | Reduced |
| Charles Schwab Investment Management Inc | 482,622 | $13.1M | 0.00% | +436+0.1% | Added |
| Artisan Partners Limited Partnership | 504,485 | $13.7M | 0.02% | +101,542+25.2% | Added |
| Northern Trust Corp | 511,901 | $13.9M | 0.00% | −43,509−7.8% | Reduced |
| Foresite Capital Management VI LLC | 530,000 | $14.4M | 4.36% | +530,000 | New |
| Bank of America Corp | 539,341 | $14.7M | 0.00% | −590,659−52.3% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 562,642 | $15.3M | 0.04% | +32,544+6.1% | Added |
| Wellington Management Group LLP | 597,826 | $16.3M | 0.00% | −1,873,590−75.8% | Reduced |
| SCS Capital Management LLC | 598,765 | $16.3M | 0.17% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 635,069 | $17.3M | 0.03% | +139,578+28.2% | Added |
| Price T Rowe Associates Inc | 637,886 | $17.4M | 0.00% | −1,019,052−61.5% | Reduced |
| Capital International Investors | 703,865 | $19.2M | 0.00% | +703,865 | New |
| Rock Springs Capital Management LP | 799,163 | $21.8M | 1.12% | −159,379−16.6% | Reduced |
| Morgan Stanley | 894,037 | $24.3M | 0.00% | +477,039+114.4% | Added |
| Dimensional Fund Advisors LP | 1,004,341 | $27.3M | 0.01% | −16,860−1.7% | Reduced |
| Goldman Sachs Group Inc | 1,033,974 | $28.1M | 0.00% | +229,208+28.5% | Added |
| Jane Street Group, LLC | 1,121,050 | $30.5M | 0.04% | +725,930+183.7% | Added |
| Susquehanna International Group, LLP | 1,142,432 | $31.1M | 0.04% | +1,142,432 | New |
| TCG Crossover Management, LLC | 1,181,841 | $32.2M | 1.06% | −248,200−17.4% | Reduced |
| GW&K Investment Management, LLC | 1,207,301 | $32.9M | 0.28% | +354,359+41.5% | Added |
| Frazier Life Sciences Management, L.P. | 1,279,754 | $34.8M | 0.94% | 00.0% | Unchanged |
| MPM Oncology Impact Management LP | 1,303,373 | $35.5M | 4.06% | +1,303,373 | New |
| Citadel Advisors LLC | 1,348,968 | $36.7M | 0.02% | +856,986+174.2% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,360,730 | $37.0M | 0.04% | +373,391+37.8% | Added |
| Geode Capital Management, LLC | 1,413,538 | $38.5M | 0.00% | −2,777−0.2% | Reduced |
| Nomura Asset Management International Inc. | 1,701,409 | $46.3M | 0.07% | +1,701,409 | New |
| D. E. Shaw & Co., Inc. | 1,837,186 | $50.0M | 0.04% | +1,469,437+399.6% | Added |
| Erste Asset Management GmbH | 2,804,900 | $76.3M | 0.64% | +40,000+1.4% | Added |
| Armistice Capital, LLC | 3,036,000 | $82.6M | 2.02% | +2,272,000+297.4% | Added |
| State Street Corp | 3,108,145 | $84.6M | 0.00% | +845,433+37.4% | Added |
| Farallon Capital Management, L.L.C. | 5,159,505 | $140.4M | 0.73% | −621,561−10.8% | Reduced |
| BlackRock, Inc. | 5,235,429 | $142.5M | 0.00% | +689,691+15.2% | Added |
| Vanguard Group Inc | 5,594,353 | $152.3M | 0.00% | −10,523−0.2% | Reduced |
| Bellevue Group AG | 0 | $0 | 0.00% | −3,714,736−100.0% | Sold out |
| Paradigm Biocapital Advisors LP | 0 | $0 | 0.00% | −2,673,555−100.0% | Sold out |
| Commodore Capital LP | 0 | $0 | 0.00% | −2,338,287−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −1,958,101−100.0% | Sold out |
| Caligan Partners LP | 0 | $0 | 0.00% | −1,131,205−100.0% | Sold out |
| Fisher Asset Management, LLC | 0 | $0 | 0.00% | −870,145−100.0% | Sold out |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −800,000−100.0% | Sold out |
| SummitTX Capital, L.P. | 0 | $0 | 0.00% | −262,977−100.0% | Sold out |
| Eagle Health Investments LP | 0 | $0 | 0.00% | −246,230−100.0% | Sold out |
| Baker Bros. Advisors LP | 0 | $0 | 0.00% | −189,866−100.0% | Sold out |
| Peregrine Capital Management LLC | 0 | $0 | 0.00% | −162,905−100.0% | Sold out |
| Alyeska Investment Group, L.P. | 0 | $0 | 0.00% | −146,514−100.0% | Sold out |
| Patient Square Capital LP | 0 | $0 | 0.00% | −133,827−100.0% | Sold out |
| Nantahala Capital Management, LLC | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |
| Phocas Financial Corp. | 0 | $0 | 0.00% | −46,608−100.0% | Sold out |
| Ameriprise Financial Inc | 0 | $0 | 0.00% | −38,428−100.0% | Sold out |
| Guggenheim Capital LLC | 0 | $0 | 0.00% | −15,902−100.0% | Sold out |
| Henshaw Capital LLC | 0 | $0 | 0.00% | −13,227−100.0% | Sold out |
| Savvy Advisors, Inc. | 0 | $0 | 0.00% | −11,993−100.0% | Sold out |
| Omers Administration Corp | 0 | $0 | 0.00% | −11,200−100.0% | Sold out |
| Cinctive Capital Management LP | 0 | $0 | 0.00% | −10,099−100.0% | Sold out |
| Voleon Capital Management LP | 0 | $0 | 0.00% | −6,682−100.0% | Sold out |
| Cerity Partners LLC | 0 | $0 | 0.00% | −6,439−100.0% | Sold out |
| Northcape Wealth Management, LLC | 0 | $0 | 0.00% | −5,240−100.0% | Sold out |
| North Star Asset Management Inc | 0 | $0 | 0.00% | −5,000−100.0% | Sold out |
| Torno Capital, LLC | 0 | $0 | 0.00% | −2,500−100.0% | Sold out |
| BIT Capital GmbH | 0 | $0 | 0.00% | −1,571−100.0% | Sold out |
| GWM Advisors LLC | 0 | $0 | 0.00% | −1,273−100.0% | Sold out |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −350−100.0% | Sold out |
| Optiver Holding B.V. | 0 | $0 | 0.00% | −310−100.0% | Sold out |
| Clearstead Advisors, LLC | 0 | $0 | 0.00% | −291−100.0% | Sold out |
| NBC Securities, Inc. | 0 | $0 | 0.00% | −241−100.0% | Sold out |
| Spire Wealth Management | 0 | $0 | 0.00% | −230−100.0% | Sold out |
| Mather Group, LLC. | 0 | $0 | 0.00% | −95−100.0% | Sold out |
| Larson Financial Group LLC | 0 | $0 | 0.00% | −74−100.0% | Sold out |
| JPL Wealth Management, LLC | 0 | $0 | 0.00% | −70−100.0% | Sold out |
| Halbert Hargrove Global Advisors, LLC | 0 | $0 | 0.00% | −47−100.0% | Sold out |
| Fifth Third Bancorp | 0 | $0 | 0.00% | −30−100.0% | Sold out |
| MAI Capital Management | 0 | $0 | 0.00% | −25−100.0% | Sold out |
| True Wealth Design, LLC | 0 | $0 | 0.00% | −9−100.0% | Sold out |
| Wealthspire Advisors, LLC | 0 | $0 | 0.00% | −6−100.0% | Sold out |
| HFM Investment Advisors, LLC | 0 | $0 | 0.00% | −3−100.0% | Sold out |
| DiNuzzo Private Wealth, Inc. | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| Cloud Capital Management, LLC | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| AXA Investment Managers S.A. | – | – | – | – | Not filed |
| Cubist Systematic Strategies, LLC | – | – | – | – | Not filed |
| CIBC Bancorp USA Inc. | – | – | – | – | Not filed |
| Hemington Wealth Management | – | – | – | – | Not filed |