Septerna, Inc.
SEPN- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001984086
近 90 天，Septerna, Inc. 內部人申報 0 筆公開市場買進、7 筆賣出；2026 年第 2 季末有 153 家機構在 13F 申報持有，市值合計 $15.8 億；沒有大師持有。
2025 年第 2 季 13F 持有人
Septerna, Inc. 在 2025/6/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 89
- 較 2025 年第 1 季 +19 家
- 持有股數
- 4,443 萬
- 較 2025 年第 1 季 −83.9 萬 (−1.9%)
- 總市值
- $4.70 億
- 較 2025 年第 1 季 +$2.08 億 (+79.2%)
- 新進機構
- 25
- 另有 31 家加碼
- 清倉機構
- 6
- 另有 19 家減碼
另有 1 家機構在 2025 年第 1 季持有、還沒有申報 2025 年第 2 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 SEPN 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 153 | $15.8 億 |
| 2026 年第 1 季 | 124 | $11.0 億 |
| 2025 年第 4 季 | 122 | $12.7 億 |
| 2025 年第 3 季 | 82 | $8.38 億 |
| 2025 年第 2 季 | 89 | $4.70 億 |
| 2025 年第 1 季 | 71 | $2.62 億 |
| 2024 年第 4 季 | 71 | $10.1 億 |
| 2024 年第 3 季 | 0 | $0 |
| 2024 年第 2 季 | 0 | $0 |
| 2024 年第 1 季 | 0 | $0 |
| 2023 年第 4 季 | 0 | $0 |
| 2023 年第 3 季 | 0 | $0 |
| 2023 年第 2 季 | 0 | $0 |
| 2023 年第 1 季 | 0 | $0 |
| 2022 年第 4 季 | 0 | $0 |
| 2022 年第 3 季 | 0 | $0 |
| 2022 年第 2 季 | 0 | $0 |
| 2022 年第 1 季 | 0 | $0 |
| 2021 年第 4 季 | 0 | $0 |
| 2021 年第 3 季 | 0 | $0 |
| 2021 年第 2 季 | 0 | $0 |
| 2021 年第 1 季 | 0 | $0 |
2025 年第 2 季持有機構
每家機構持有 Septerna, Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 1 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 6,995,858 | $7,395 萬 | 1.25% | 00.0% | 不變 |
| TRV GP V, LLC | 6,215,591 | $6,570 萬 | 39.66% | 00.0% | 不變 |
| Driehaus Capital Management LLC | 4,680,431 | $4,947 萬 | 0.40% | +1,557,823+49.9% | 加碼 |
| BVF Inc | 4,396,124 | $4,647 萬 | 1.66% | 00.0% | 不變 |
| TRV GP VI, LLC | 4,211,659 | $4,452 萬 | 69.32% | 00.0% | 不變 |
| Samsara BioCapital, LLC | 3,149,128 | $3,329 萬 | 6.81% | 00.0% | 不變 |
| Siren, L.L.C. | 2,202,514 | $2,328 萬 | 1.20% | 00.0% | 不變 |
| Goldman Sachs Group Inc | 1,416,314 | $1,497 萬 | 0.00% | −33,085−2.3% | 減碼 |
| Vanguard Group Inc | 1,414,363 | $1,495 萬 | 0.00% | +419,319+42.1% | 加碼 |
| BlackRock, Inc. | 1,390,800 | $1,470 萬 | 0.00% | +132,487+10.5% | 加碼 |
| Avoro Capital Advisors LLC | 1,237,500 | $1,308 萬 | 0.23% | −100,000−7.5% | 減碼 |
| ADAR1 Capital Management, LLC | 847,227 | $895.5 萬 | 1.45% | +126,379+17.5% | 加碼 |
| Checkpoint Capital L.P. | 586,473 | $619.9 萬 | 2.89% | −238,405−28.9% | 減碼 |
| Sio Capital Management, LLC | 584,435 | $617.7 萬 | 2.48% | −204,235−25.9% | 減碼 |
| Casdin Capital, LLC | 553,268 | $584.8 萬 | 0.53% | 00.0% | 不變 |
| Perceptive Advisors LLC | 541,450 | $572.3 萬 | 0.21% | +541,450 | 新進 |
| VR Adviser, LLC | 540,453 | $571.3 萬 | 0.43% | +540,453 | 新進 |
| Geode Capital Management, LLC | 487,956 | $515.8 萬 | 0.00% | +78,316+19.1% | 加碼 |
| State Street Corp | 369,992 | $391.1 萬 | 0.00% | +25,388+7.4% | 加碼 |
| Catalio Capital Management, LP | 294,360 | $311.1 萬 | 0.65% | −729,885−71.3% | 減碼 |
| Woodline Partners LP | 282,585 | $298.7 萬 | 0.02% | −300,000−51.5% | 減碼 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 222,702 | $235.4 萬 | 0.00% | +119,953+116.7% | 加碼 |
| Susquehanna International Group, LLP | 166,506 | $176.0 萬 | 0.00% | +141,297+560.5% | 加碼 |
| Charles Schwab Investment Management Inc | 154,781 | $163.6 萬 | 0.00% | +36,330+30.7% | 加碼 |
| Northern Trust Corp | 154,344 | $163.1 萬 | 0.00% | −3,696−2.3% | 減碼 |
| Deep Track Capital, LP | 121,716 | $128.7 萬 | 0.04% | −1,791,213−93.6% | 減碼 |
| Logos Global Management LP | 109,202 | $115.4 萬 | 0.15% | −25,000−18.6% | 減碼 |
| Bank of America Corp | 99,213 | $104.9 萬 | 0.00% | +87,654+758.3% | 加碼 |
| Morgan Stanley | 84,860 | $89.7 萬 | 0.00% | −6,184−6.8% | 減碼 |
| Two Sigma Investments, LP | 77,642 | $82.1 萬 | 0.00% | +2,801+3.7% | 加碼 |
| Soleus Capital Management, L.P. | 75,456 | $79.8 萬 | 0.06% | −675,897−90.0% | 減碼 |
| UBS Group AG | 72,335 | $76.5 萬 | 0.00% | −167,595−69.9% | 減碼 |
| Rangeley Capital, LLC | 58,605 | $61.9 萬 | 0.78% | +5,655+10.7% | 加碼 |
| Nuveen, LLC | 57,971 | $61.3 萬 | 0.00% | +34,010+141.9% | 加碼 |
| Millennium Management LLC | 51,944 | $54.9 萬 | 0.00% | −384,620−88.1% | 減碼 |
| Bank of New York Mellon Corp | 48,489 | $51.3 萬 | 0.00% | +10,113+26.4% | 加碼 |
| Barclays PLC | 35,706 | $37.7 萬 | 0.00% | +12,973+57.1% | 加碼 |
| Alyeska Investment Group, L.P. | 35,000 | $37.0 萬 | 0.00% | 00.0% | 不變 |
| UBS Asset Management Americas Inc | 28,700 | $30.3 萬 | 0.00% | +28,700 | 新進 |
| Rhumbline Advisers | 28,572 | $30.2 萬 | 0.00% | +5,254+22.5% | 加碼 |
| Price T Rowe Associates Inc | 24,902 | $26.4 萬 | 0.00% | +1,945+8.5% | 加碼 |
| Boothbay Fund Management, LLC | 24,142 | $25.5 萬 | 0.01% | +24,142 | 新進 |
| Gsa Capital Partners LLP | 23,527 | $24.9 萬 | 0.02% | +5,228+28.6% | 加碼 |
| Simplex Trading, LLC | 23,525 | $24.8 萬 | 0.01% | +23,495+78,316.7% | 加碼 |
| XTX Topco Ltd | 22,330 | $23.6 萬 | 0.01% | −15,020−40.2% | 減碼 |
| Alliancebernstein L.P. | 22,100 | $23.4 萬 | 0.00% | +22,100 | 新進 |
| Citadel Advisors LLC | 17,774 | $18.8 萬 | 0.00% | +17,774 | 新進 |
| Tudor Investment Corp Et Al | 16,761 | $17.7 萬 | 0.00% | +16,761 | 新進 |
| Wells Fargo & Company | 14,717 | $15.6 萬 | 0.00% | +3,848+35.4% | 加碼 |
| MetLife Investment Management | 13,685 | $14.5 萬 | 0.00% | +13,685 | 新進 |
| Congress Wealth Management LLC | 12,589 | $13.3 萬 | 0.00% | +12,589 | 新進 |
| Intech Investment Management LLC | 12,200 | $12.9 萬 | 0.00% | +12,200 | 新進 |
| Deutsche Bank AG | 12,123 | $12.8 萬 | 0.00% | −3,845−24.1% | 減碼 |
| Invesco Ltd. | 11,833 | $12.5 萬 | 0.00% | −369−3.0% | 減碼 |
| Mirae Asset Global ETFs Holdings Ltd. | 11,697 | $12.4 萬 | 0.00% | +710+6.5% | 加碼 |
| Squarepoint Ops LLC | 10,737 | $11.3 萬 | 0.00% | +10,737 | 新進 |
| Quadrature Capital Ltd | 10,125 | $10.7 萬 | 0.00% | +10,125 | 新進 |
| PharVision Advisers, LLC | 10,152 | $10.7 萬 | 0.15% | +10,152 | 新進 |
| JPMorgan Chase & Co | 10,101 | $10.7 萬 | 0.00% | +1,315+15.0% | 加碼 |
| Citigroup Inc | 7,173 | $7.58 萬 | 0.00% | −30,882−81.2% | 減碼 |
| Quarry LP | 3,601 | $3.81 萬 | 0.01% | +3,601 | 新進 |
| Police & Firemen's Retirement System of New Jersey | 3,555 | $3.76 萬 | 0.00% | 00.0% | 不變 |
| STRS Ohio | 3,400 | $3.59 萬 | 0.00% | 00.0% | 不變 |
| New York State Common Retirement Fund | 2,900 | $3.07 萬 | 0.00% | 00.0% | 不變 |
| FMR LLC | 2,485 | $2.63 萬 | 0.00% | −47,293−95.0% | 減碼 |
| Covestor Ltd | 2,324 | $2.40 萬 | 0.01% | +2,318+38,633.3% | 加碼 |
| Tower Research Capital LLC (TRC) | 2,225 | $2.35 萬 | 0.00% | +437+24.4% | 加碼 |
| BNP Paribas Arbitrage, SA | 2,210 | $2.34 萬 | 0.00% | +1,061+92.3% | 加碼 |
| Legal & General Group Plc | 1,945 | $2.06 萬 | 0.00% | +105+5.7% | 加碼 |
| Ameritas Investment Partners, Inc. | 1,944 | $2.05 萬 | 0.00% | 00.0% | 不變 |
| Royal Bank of Canada | 1,840 | $1.90 萬 | 0.00% | +1,038+129.4% | 加碼 |
| California State Teachers Retirement System | 1,370 | $1.45 萬 | 0.00% | −42,992−96.9% | 減碼 |
| Signaturefd, LLC | 966 | $1.02 萬 | 0.00% | +966 | 新進 |
| CWM, LLC | 872 | $9,000 | 0.00% | +590+209.2% | 加碼 |
| Group One Trading, L.P. | 789 | $8,340 | 0.00% | +789 | 新進 |
| Amalgamated Bank | 634 | $7,000 | 0.00% | 00.0% | 不變 |
| Caitong International Asset Management Co., Ltd | 605 | $6,395 | 0.00% | +605 | 新進 |
| GAMMA Investing LLC | 577 | $6,099 | 0.00% | +143+32.9% | 加碼 |
| Sterling Capital Management LLC | 577 | $6,099 | 0.00% | +420+267.5% | 加碼 |
| US Bancorp | 265 | $2,801 | 0.00% | +265 | 新進 |
| Raymond James Financial Inc | 222 | $2,347 | 0.00% | +222 | 新進 |
| Advisor Group Holdings, Inc. | 214 | $2,262 | 0.00% | +214 | 新進 |
| Comerica Bank | 212 | $2,241 | 0.00% | +212 | 新進 |
| Nisa Investment Advisors, LLC | 143 | $1,512 | 0.00% | +9+6.7% | 加碼 |
| Fortitude Family Office, LLC | 71 | $750 | 0.00% | +71 | 新進 |
| SBI Securities Co., Ltd. | 50 | $529 | 0.00% | +50 | 新進 |
| Rothschild Investment LLC | 30 | $317 | 0.00% | +30 | 新進 |
| EverSource Wealth Advisors, LLC | 22 | $233 | 0.00% | +22 | 新進 |
| National Bank of Canada | 8 | $85 | 0.00% | 00.0% | 不變 |
| Stonepine Capital Management, LLC | 0 | $0 | 0.00% | −68,084−100.0% | 清倉 |
| Swiss National Bank | 0 | $0 | 0.00% | −30,100−100.0% | 清倉 |
| Stoneridge Investment Partners LLC | 0 | $0 | 0.00% | −18,477−100.0% | 清倉 |
| Chicago Partners Investment Group LLC | 0 | $0 | 0.00% | −10,954−100.0% | 清倉 |
| Corebridge Financial, Inc. | 0 | $0 | 0.00% | −9,102−100.0% | 清倉 |
| KLP Kapitalforvaltning AS | 0 | $0 | 0.00% | −8,400−100.0% | 清倉 |
| Lindbrook Capital, LLC | – | – | – | – | 本季未申報 |