Septerna, Inc.
SEPN- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001984086
近 90 天，Septerna, Inc. 內部人申報 0 筆公開市場買進、7 筆賣出；2026 年第 2 季末有 153 家機構在 13F 申報持有，市值合計 $15.8 億；沒有大師持有。
2026 年第 1 季 13F 持有人
Septerna, Inc. 在 2026/3/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 124
- 較 2025 年第 4 季 +4 家
- 持有股數
- 4,572 萬
- 較 2025 年第 4 季 +164.3 萬 (+3.7%)
- 總市值
- $11.0 億
- 較 2025 年第 4 季 −$1.30 億 (−10.6%)
- 新進機構
- 28
- 另有 43 家加碼
- 清倉機構
- 24
- 另有 30 家減碼
另有 2 家機構在 2025 年第 4 季持有、還沒有申報 2026 年第 1 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 SEPN 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 153 | $15.8 億 |
| 2026 年第 1 季 | 124 | $11.0 億 |
| 2025 年第 4 季 | 122 | $12.7 億 |
| 2025 年第 3 季 | 82 | $8.38 億 |
| 2025 年第 2 季 | 89 | $4.70 億 |
| 2025 年第 1 季 | 71 | $2.62 億 |
| 2024 年第 4 季 | 71 | $10.1 億 |
| 2024 年第 3 季 | 0 | $0 |
| 2024 年第 2 季 | 0 | $0 |
| 2024 年第 1 季 | 0 | $0 |
| 2023 年第 4 季 | 0 | $0 |
| 2023 年第 3 季 | 0 | $0 |
| 2023 年第 2 季 | 0 | $0 |
| 2023 年第 1 季 | 0 | $0 |
| 2022 年第 4 季 | 0 | $0 |
| 2022 年第 3 季 | 0 | $0 |
| 2022 年第 2 季 | 0 | $0 |
| 2022 年第 1 季 | 0 | $0 |
| 2021 年第 4 季 | 0 | $0 |
| 2021 年第 3 季 | 0 | $0 |
| 2021 年第 2 季 | 0 | $0 |
| 2021 年第 1 季 | 0 | $0 |
2026 年第 1 季持有機構
每家機構持有 Septerna, Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 4 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 6,995,858 | $1.68 億 | 1.78% | 00.0% | 不變 |
| TRV GP V, LLC | 6,215,591 | $1.49 億 | 37.25% | 00.0% | 不變 |
| Driehaus Capital Management LLC | 4,395,572 | $1.06 億 | 0.78% | −413,898−8.6% | 減碼 |
| TRV GP VI, LLC | 4,211,659 | $1.01 億 | 74.64% | 00.0% | 不變 |
| Samsara BioCapital, LLC | 3,149,128 | $7,567 萬 | 7.35% | 00.0% | 不變 |
| Goldman Sachs Group Inc | 2,906,427 | $6,984 萬 | 0.01% | +191,298+7.0% | 加碼 |
| Siren, L.L.C. | 2,000,000 | $4,806 萬 | 1.33% | 00.0% | 不變 |
| BlackRock, Inc. | 1,822,174 | $4,379 萬 | 0.00% | +20,846+1.2% | 加碼 |
| BVF Inc | 1,353,249 | $3,252 萬 | 1.04% | −367,533−21.4% | 減碼 |
| Avoro Capital Advisors LLC | 1,337,500 | $3,214 萬 | 0.32% | 00.0% | 不變 |
| Vanguard Capital Management LLC | 1,196,962 | $2,876 萬 | 0.00% | +1,196,962 | 新進 |
| ADAR1 Capital Management, LLC | 1,089,818 | $2,619 萬 | 1.57% | −67,793−5.9% | 減碼 |
| Primecap Management Co | 1,048,834 | $2,520 萬 | 0.02% | +502,734+92.1% | 加碼 |
| Janus Henderson Group PLC | 890,754 | $2,133 萬 | 0.01% | +890,754 | 新進 |
| First Light Asset Management, LLC | 732,860 | $1,761 萬 | 1.58% | +112,049+18.0% | 加碼 |
| Geode Capital Management, LLC | 645,146 | $1,551 萬 | 0.00% | +72,412+12.6% | 加碼 |
| State Street Corp | 631,447 | $1,517 萬 | 0.00% | +91,419+16.9% | 加碼 |
| Casdin Capital, LLC | 553,268 | $1,330 萬 | 1.01% | 00.0% | 不變 |
| VR Adviser, LLC | 506,056 | $1,216 萬 | 0.45% | −104,752−17.1% | 減碼 |
| Catalio Capital Management, LP | 294,360 | $707.3 萬 | 1.48% | 00.0% | 不變 |
| Soleus Capital Management, L.P. | 275,000 | $660.8 萬 | 0.27% | −108,368−28.3% | 減碼 |
| Balyasny Asset Management LLC | 236,679 | $568.7 萬 | 0.01% | +233,108+6,527.8% | 加碼 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 223,995 | $538.3 萬 | 0.01% | +1,293+0.6% | 加碼 |
| Vanguard Portfolio Management LLC | 195,043 | $468.7 萬 | 0.00% | +195,043 | 新進 |
| Kalehua Capital Management LLC | 194,544 | $467.5 萬 | 3.31% | 00.0% | 不變 |
| Charles Schwab Investment Management Inc | 181,580 | $436.3 萬 | 0.00% | −5,661−3.0% | 減碼 |
| Northern Trust Corp | 164,530 | $395.4 萬 | 0.00% | +10,334+6.7% | 加碼 |
| Vanguard Fiduciary Trust Co | 154,484 | $371.2 萬 | 0.00% | +154,484 | 新進 |
| Millennium Management LLC | 124,101 | $298.2 萬 | 0.00% | +16,638+15.5% | 加碼 |
| UBS Group AG | 116,979 | $281.1 萬 | 0.00% | +48,162+70.0% | 加碼 |
| Morgan Stanley | 110,530 | $265.6 萬 | 0.00% | +6,545+6.3% | 加碼 |
| Hussman Strategic Advisors, Inc. | 105,000 | $252.3 萬 | 0.55% | +105,000 | 新進 |
| Checkpoint Capital L.P. | 100,300 | $241.0 萬 | 0.86% | +100,300 | 新進 |
| Federated Hermes, Inc. | 89,301 | $214.6 萬 | 0.00% | +10,396+13.2% | 加碼 |
| Invesco Ltd. | 82,868 | $199.1 萬 | 0.00% | −79,146−48.9% | 減碼 |
| JPMorgan Chase & Co | 84,674 | $197.3 萬 | 0.00% | +16,336+23.9% | 加碼 |
| Two Sigma Investments, LP | 75,367 | $181.1 萬 | 0.00% | −17,442−18.8% | 減碼 |
| Longaeva Partners L.P. | 74,567 | $179.2 萬 | 0.09% | +24,665+49.4% | 加碼 |
| American Century Companies Inc | 61,290 | $147.3 萬 | 0.00% | +10,601+20.9% | 加碼 |
| Bank of New York Mellon Corp | 58,709 | $141.1 萬 | 0.00% | +3,377+6.1% | 加碼 |
| Jump Financial, LLC | 53,011 | $127.4 萬 | 0.02% | +44,612+531.2% | 加碼 |
| Sofinnova Investments, Inc. | 47,506 | $114.2 萬 | 0.06% | +47,506 | 新進 |
| Marshall Wace, LLP | 39,840 | $95.7 萬 | 0.00% | −187,061−82.4% | 減碼 |
| Rangeley Capital, LLC | 39,800 | $95.6 萬 | 1.03% | −26,000−39.5% | 減碼 |
| Renaissance Technologies LLC | 37,700 | $90.6 萬 | 0.00% | +37,700 | 新進 |
| XTX Topco Ltd | 36,723 | $88.2 萬 | 0.02% | +13,408+57.5% | 加碼 |
| Trexquant Investment LP | 35,301 | $84.8 萬 | 0.01% | −8,704−19.8% | 減碼 |
| Alyeska Investment Group, L.P. | 35,000 | $84.1 萬 | 0.00% | 00.0% | 不變 |
| Acadian Asset Management LLC | 30,978 | $74.1 萬 | 0.00% | +101+0.3% | 加碼 |
| Nuveen, LLC | 29,176 | $70.1 萬 | 0.00% | +3,378+13.1% | 加碼 |
| Jacobs Levy Equity Management, Inc | 28,436 | $68.3 萬 | 0.00% | −32,934−53.7% | 減碼 |
| Price T Rowe Associates Inc | 28,076 | $67.5 萬 | 0.00% | +2,633+10.3% | 加碼 |
| Rhumbline Advisers | 26,604 | $63.9 萬 | 0.00% | +185+0.7% | 加碼 |
| Bank of America Corp | 25,973 | $62.4 萬 | 0.00% | −11,621−30.9% | 減碼 |
| Y-Intercept (Hong Kong) Ltd | 25,770 | $61.9 萬 | 0.01% | +25,770 | 新進 |
| Adage Capital Partners GP, L.L.C. | 24,000 | $57.7 萬 | 0.00% | +24,000 | 新進 |
| Logos Global Management LP | 23,548 | $56.6 萬 | 0.03% | 00.0% | 不變 |
| FMR LLC | 23,446 | $56.3 萬 | 0.00% | +20,139+609.0% | 加碼 |
| Alliancebernstein L.P. | 19,600 | $54.6 萬 | 0.00% | 00.0% | 不變 |
| Barclays PLC | 22,714 | $54.6 萬 | 0.00% | −15,433−40.5% | 減碼 |
| Swiss National Bank | 22,100 | $53.1 萬 | 0.00% | +22,100 | 新進 |
| Algert Global LLC | 21,035 | $50.5 萬 | 0.01% | −13,909−39.8% | 減碼 |
| Squarepoint Ops LLC | 18,083 | $43.5 萬 | 0.00% | +3,236+21.8% | 加碼 |
| STRS Ohio | 17,200 | $41.3 萬 | 0.00% | +2,600+17.8% | 加碼 |
| Deutsche Bank AG | 16,843 | $40.5 萬 | 0.00% | +1,964+13.2% | 加碼 |
| VARCOV Co. | 16,752 | $40.3 萬 | 0.15% | −5,882−26.0% | 減碼 |
| Engineers Gate Manager LP | 16,528 | $39.7 萬 | 0.00% | +16,528 | 新進 |
| Vanguard Global Advisers, LLC | 16,247 | $39.0 萬 | 0.00% | +16,247 | 新進 |
| AQR Capital Management LLC | 15,375 | $36.9 萬 | 0.00% | +7,549+96.5% | 加碼 |
| Numerai GP LLC | 15,082 | $36.2 萬 | 0.04% | −30,784−67.1% | 減碼 |
| Los Angeles Capital Management LLC | 14,214 | $34.2 萬 | 0.00% | −4,336−23.4% | 減碼 |
| MetLife Investment Management | 13,685 | $32.9 萬 | 0.00% | 00.0% | 不變 |
| EntryPoint Capital, LLC | 12,776 | $30.7 萬 | 0.09% | +12,776 | 新進 |
| Advisor Group Holdings, Inc. | 12,698 | $30.5 萬 | 0.00% | +50.0% | 加碼 |
| Verition Fund Management LLC | 12,343 | $29.7 萬 | 0.00% | +12,343 | 新進 |
| China Universal Asset Management Co., Ltd. | 11,946 | $28.7 萬 | 0.02% | +1,650+16.0% | 加碼 |
| Man Group plc | 11,858 | $28.5 萬 | 0.00% | +11,858 | 新進 |
| Russell Investments Group, Ltd. | 11,515 | $27.7 萬 | 0.00% | −3,795−24.8% | 減碼 |
| Seven Fleet Capital Management LP | 11,445 | $27.5 萬 | 0.09% | 00.0% | 不變 |
| Virtus Investment Advisers, Inc. | 10,719 | $25.8 萬 | 0.07% | +262+2.5% | 加碼 |
| Massachusetts Financial Services Co | 10,382 | $24.9 萬 | 0.00% | +10,382 | 新進 |
| Mirae Asset Global ETFs Holdings Ltd. | 10,021 | $24.1 萬 | 0.00% | +87+0.9% | 加碼 |
| Wells Fargo & Company | 9,869 | $23.7 萬 | 0.00% | −16,660−62.8% | 減碼 |
| Citigroup Inc | 9,195 | $22.1 萬 | 0.00% | −366−3.8% | 減碼 |
| Winton Group Ltd | 8,842 | $21.2 萬 | 0.01% | +8,842 | 新進 |
| Vanguard Asset Management, Ltd | 7,420 | $17.8 萬 | 0.00% | +7,420 | 新進 |
| Legal & General Group Plc | 5,735 | $13.8 萬 | 0.00% | +3,790+194.9% | 加碼 |
| New York State Common Retirement Fund | 5,600 | $13.5 萬 | 0.00% | 00.0% | 不變 |
| BNP Paribas Arbitrage, SA | 5,361 | $12.9 萬 | 0.00% | −88−1.6% | 減碼 |
| Police & Firemen's Retirement System of New Jersey | 5,175 | $12.4 萬 | 0.00% | 00.0% | 不變 |
| Vanguard Investments Australia, Ltd. | 3,895 | $9.36 萬 | 0.00% | +3,895 | 新進 |
| Public Employees Retirement System of Ohio | 3,374 | $8.11 萬 | 0.00% | −7,220−68.2% | 減碼 |
| KLP Kapitalforvaltning AS | 2,500 | $6.01 萬 | 0.00% | +2,500 | 新進 |
| Mirae Asset Global Investments Co., Ltd. | 2,335 | $5.61 萬 | 0.00% | +159+7.3% | 加碼 |
| Covestor Ltd | 2,260 | $5.40 萬 | 0.04% | +319+16.4% | 加碼 |
| Ameritas Investment Partners, Inc. | 1,944 | $4.67 萬 | 0.00% | 00.0% | 不變 |
| California State Teachers Retirement System | 1,157 | $2.78 萬 | 0.00% | −159−12.1% | 減碼 |
| GAMMA Investing LLC | 1,110 | $2.67 萬 | 0.00% | +194+21.2% | 加碼 |
| GF Fund Management Co. Ltd. | 1,006 | $2.42 萬 | 0.00% | +128+14.6% | 加碼 |
| Signaturefd, LLC | 966 | $2.32 萬 | 0.00% | −23−2.3% | 減碼 |