Septerna, Inc.
SEPN- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001984086
近 90 天，Septerna, Inc. 內部人申報 0 筆公開市場買進、8 筆賣出；2026 年第 2 季末有 153 家機構在 13F 申報持有，市值合計 $15.9 億；沒有大師持有。
2026 年第 2 季 13F 持有人
Septerna, Inc. 在 2026/6/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 153
- 較 2026 年第 1 季 +31 家
- 持有股數
- 4,744 萬
- 較 2026 年第 1 季 +241.3 萬 (+5.4%)
- 總市值
- $15.9 億
- 較 2026 年第 1 季 +$5.07 億 (+46.8%)
- 新進機構
- 47
- 另有 49 家加碼
- 清倉機構
- 16
- 另有 32 家減碼
另有 2 家機構在 2026 年第 1 季持有、還沒有申報 2026 年第 2 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 SEPN 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 153 | $15.9 億 |
| 2026 年第 1 季 | 124 | $11.0 億 |
| 2025 年第 4 季 | 122 | $12.7 億 |
| 2025 年第 3 季 | 82 | $8.38 億 |
| 2025 年第 2 季 | 89 | $4.70 億 |
| 2025 年第 1 季 | 71 | $2.62 億 |
| 2024 年第 4 季 | 71 | $10.1 億 |
| 2024 年第 3 季 | 0 | $0 |
| 2024 年第 2 季 | 0 | $0 |
| 2024 年第 1 季 | 0 | $0 |
| 2023 年第 4 季 | 0 | $0 |
| 2023 年第 3 季 | 0 | $0 |
| 2023 年第 2 季 | 0 | $0 |
| 2023 年第 1 季 | 0 | $0 |
| 2022 年第 4 季 | 0 | $0 |
| 2022 年第 3 季 | 0 | $0 |
| 2022 年第 2 季 | 0 | $0 |
| 2022 年第 1 季 | 0 | $0 |
| 2021 年第 4 季 | 0 | $0 |
| 2021 年第 3 季 | 0 | $0 |
| 2021 年第 2 季 | 0 | $0 |
| 2021 年第 1 季 | 0 | $0 |
2026 年第 2 季持有機構
每家機構持有 Septerna, Inc. 的股數、市值與佔組合比重；股數變化跟 2026 年第 1 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 6,995,858 | $2.34 億 | 2.04% | 00.0% | 不變 |
| TRV GP V, LLC | 6,215,591 | $2.08 億 | 41.78% | 00.0% | 不變 |
| Driehaus Capital Management LLC | 4,433,058 | $1.48 億 | 0.86% | +37,486+0.9% | 加碼 |
| TRV GP VI, LLC | 4,211,659 | $1.41 億 | 60.72% | 00.0% | 不變 |
| Samsara BioCapital, LLC | 3,149,128 | $1.05 億 | 8.66% | 00.0% | 不變 |
| Goldman Sachs Group Inc | 3,062,766 | $1.03 億 | 0.01% | +156,339+5.4% | 加碼 |
| BlackRock, Inc. | 1,932,088 | $6,471 萬 | 0.00% | +109,914+6.0% | 加碼 |
| Siren, L.L.C. | 1,900,000 | $6,363 萬 | 1.29% | −100,000−5.0% | 減碼 |
| Avoro Capital Advisors LLC | 1,337,500 | $4,479 萬 | 0.40% | 00.0% | 不變 |
| Jupiter Topco LLC | 1,307,500 | $4,372 萬 | 0.02% | +1,307,500 | 新進 |
| Vanguard Capital Management LLC | 1,221,673 | $4,091 萬 | 0.00% | +24,711+2.1% | 加碼 |
| Primecap Management Co | 1,167,382 | $3,910 萬 | 0.02% | +118,548+11.3% | 加碼 |
| First Light Asset Management, LLC | 963,260 | $3,226 萬 | 1.96% | +230,400+31.4% | 加碼 |
| ADAR1 Capital Management, LLC | 940,747 | $3,151 萬 | 1.48% | −149,071−13.7% | 減碼 |
| Geode Capital Management, LLC | 679,163 | $2,275 萬 | 0.00% | +34,017+5.3% | 加碼 |
| State Street Corp | 652,630 | $2,186 萬 | 0.00% | +21,183+3.4% | 加碼 |
| Loomis Sayles & Co L P | 624,752 | $2,092 萬 | 0.03% | +624,752 | 新進 |
| Casdin Capital, LLC | 553,268 | $1,853 萬 | 0.93% | 00.0% | 不變 |
| Catalio Capital Management, LP | 536,152 | $1,796 萬 | 3.37% | +241,792+82.1% | 加碼 |
| Algert Global LLC | 397,487 | $1,331 萬 | 0.16% | +376,452+1,789.6% | 加碼 |
| Kalehua Capital Management LLC | 389,088 | $1,303 萬 | 4.16% | 00.0% | 不變 |
| Balyasny Asset Management LLC | 350,442 | $1,174 萬 | 0.02% | +113,763+48.1% | 加碼 |
| Longaeva Partners L.P. | 298,171 | $998.6 萬 | 0.29% | +223,604+299.9% | 加碼 |
| Soleus Capital Management, L.P. | 275,000 | $921.0 萬 | 0.32% | 00.0% | 不變 |
| Vanguard Portfolio Management LLC | 230,184 | $770.9 萬 | 0.00% | +35,141+18.0% | 加碼 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 222,702 | $745.8 萬 | 0.01% | −1,293−0.6% | 減碼 |
| Two Sigma Investments, LP | 220,885 | $739.7 萬 | 0.01% | +145,518+193.1% | 加碼 |
| Northern Trust Corp | 201,131 | $673.6 萬 | 0.00% | +36,601+22.2% | 加碼 |
| Charles Schwab Investment Management Inc | 187,041 | $626.4 萬 | 0.00% | +5,461+3.0% | 加碼 |
| Woodline Partners LP | 185,535 | $621.4 萬 | 0.02% | +185,535 | 新進 |
| Vanguard Fiduciary Trust Co | 165,656 | $554.8 萬 | 0.00% | +11,172+7.2% | 加碼 |
| Morgan Stanley | 134,377 | $450.0 萬 | 0.00% | +23,847+21.6% | 加碼 |
| UBS Group AG | 89,874 | $301.0 萬 | 0.00% | −27,105−23.2% | 減碼 |
| JPMorgan Chase & Co | 85,301 | $296.4 萬 | 0.00% | +627+0.7% | 加碼 |
| Federated Hermes, Inc. | 86,753 | $290.5 萬 | 0.00% | −2,548−2.9% | 減碼 |
| Lazard Asset Management LLC | 75,425 | $252.6 萬 | 0.00% | +75,425 | 新進 |
| Dimensional Fund Advisors LP | 75,309 | $252.3 萬 | 0.00% | +75,309 | 新進 |
| Arrowstreet Capital, Limited Partnership | 74,649 | $250.0 萬 | 0.00% | +74,649 | 新進 |
| Jacobs Levy Equity Management, Inc | 68,180 | $228.3 萬 | 0.01% | +39,744+139.8% | 加碼 |
| Hussman Strategic Advisors, Inc. | 63,000 | $211.0 萬 | 0.49% | −42,000−40.0% | 減碼 |
| American Century Companies Inc | 60,973 | $204.2 萬 | 0.00% | −317−0.5% | 減碼 |
| Bank of New York Mellon Corp | 56,176 | $188.1 萬 | 0.00% | −2,533−4.3% | 減碼 |
| XTX Topco Ltd | 54,489 | $182.5 萬 | 0.02% | +17,766+48.4% | 加碼 |
| Millennium Management LLC | 50,562 | $169.3 萬 | 0.00% | −73,539−59.3% | 減碼 |
| Barclays PLC | 49,821 | $166.9 萬 | 0.00% | +27,107+119.3% | 加碼 |
| Elmind Capital, LP | 49,444 | $165.6 萬 | 0.42% | +49,444 | 新進 |
| Nuveen, LLC | 48,229 | $161.5 萬 | 0.00% | +19,053+65.3% | 加碼 |
| Sofinnova Investments, Inc. | 47,506 | $159.1 萬 | 0.08% | 00.0% | 不變 |
| D. E. Shaw & Co., Inc. | 46,483 | $155.7 萬 | 0.00% | +46,483 | 新進 |
| Jane Street Group, LLC | 45,552 | $152.6 萬 | 0.00% | +45,552 | 新進 |
| Voleon Capital Management LP | 44,435 | $148.8 萬 | 0.03% | +44,435 | 新進 |
| HRT Financial LP | 42,022 | $140.7 萬 | 0.00% | +42,022 | 新進 |
| Renaissance Technologies LLC | 41,419 | $138.7 萬 | 0.00% | +3,719+9.9% | 加碼 |
| Russell Investments Group, Ltd. | 40,209 | $134.7 萬 | 0.00% | +28,694+249.2% | 加碼 |
| Caption Management, LLC | 38,006 | $127.3 萬 | 0.04% | +38,006 | 新進 |
| Bank of America Corp | 35,875 | $120.1 萬 | 0.00% | +9,902+38.1% | 加碼 |
| Price T Rowe Associates Inc | 35,323 | $118.3 萬 | 0.00% | +7,247+25.8% | 加碼 |
| Alyeska Investment Group, L.P. | 35,000 | $117.2 萬 | 0.00% | 00.0% | 不變 |
| Brevan Howard Capital Management LP | 29,452 | $98.6 萬 | 0.01% | +29,452 | 新進 |
| HighVista Strategies LLC | 29,337 | $98.2 萬 | 0.22% | +29,337 | 新進 |
| Tudor Investment Corp Et Al | 28,966 | $97.0 萬 | 0.00% | +28,966 | 新進 |
| Rhumbline Advisers | 27,636 | $92.6 萬 | 0.00% | +1,032+3.9% | 加碼 |
| Trexquant Investment LP | 25,645 | $85.9 萬 | 0.01% | −9,656−27.4% | 減碼 |
| Invesco Ltd. | 24,094 | $80.7 萬 | 0.00% | −58,774−70.9% | 減碼 |
| Logos Global Management LP | 23,548 | $78.9 萬 | 0.03% | 00.0% | 不變 |
| FMR LLC | 23,240 | $77.8 萬 | 0.00% | −206−0.9% | 減碼 |
| Fox Run Management, L.L.C. | 22,038 | $73.8 萬 | 0.12% | +22,038 | 新進 |
| Deutsche Bank AG | 21,873 | $73.3 萬 | 0.00% | +5,030+29.9% | 加碼 |
| Alliancebernstein L.P. | 29,900 | $71.8 萬 | 0.00% | +10,300+52.6% | 加碼 |
| Squarepoint Ops LLC | 21,219 | $71.1 萬 | 0.00% | +3,136+17.3% | 加碼 |
| STRS Ohio | 21,000 | $70.3 萬 | 0.00% | +3,800+22.1% | 加碼 |
| Fred Alger Management, LLC | 20,958 | $70.2 萬 | 0.00% | +20,958 | 新進 |
| Acadian Asset Management LLC | 20,996 | $70.1 萬 | 0.00% | −9,982−32.2% | 減碼 |
| Jump Financial, LLC | 20,200 | $67.6 萬 | 0.01% | −32,811−61.9% | 減碼 |
| Swiss National Bank | 19,800 | $66.3 萬 | 0.00% | −2,300−10.4% | 減碼 |
| Wells Fargo & Company | 19,684 | $65.9 萬 | 0.00% | +9,815+99.5% | 加碼 |
| Franklin Resources Inc | 18,607 | $62.3 萬 | 0.00% | +18,607 | 新進 |
| Citigroup Inc | 17,808 | $59.6 萬 | 0.00% | +8,613+93.7% | 加碼 |
| Aquatic Capital Management LLC | 17,427 | $58.4 萬 | 0.02% | +17,427 | 新進 |
| Engineers Gate Manager LP | 17,350 | $58.1 萬 | 0.01% | +822+5.0% | 加碼 |
| BNP Paribas Arbitrage, SA | 16,946 | $56.8 萬 | 0.00% | +11,585+216.1% | 加碼 |
| Los Angeles Capital Management LLC | 16,597 | $55.6 萬 | 0.00% | +2,383+16.8% | 加碼 |
| State of Wyoming | 16,379 | $54.9 萬 | 0.06% | +16,379 | 新進 |
| Vanguard Global Advisers, LLC | 16,247 | $54.4 萬 | 0.00% | 00.0% | 不變 |
| AQR Capital Management LLC | 15,397 | $51.6 萬 | 0.00% | +22+0.1% | 加碼 |
| Virginia Retirement Systems Et Al | 13,300 | $44.5 萬 | 0.00% | +13,300 | 新進 |
| Verdad Advisers, LP | 12,970 | $43.4 萬 | 0.42% | +12,970 | 新進 |
| MetLife Investment Management | 12,880 | $43.1 萬 | 0.00% | −805−5.9% | 減碼 |
| Advisor Group Holdings, Inc. | 12,594 | $42.2 萬 | 0.00% | −104−0.8% | 減碼 |
| Man Group plc | 11,469 | $38.4 萬 | 0.00% | −389−3.3% | 減碼 |
| California State Teachers Retirement System | 10,866 | $36.4 萬 | 0.00% | +9,709+839.2% | 加碼 |
| China Universal Asset Management Co., Ltd. | 10,774 | $36.1 萬 | 0.02% | −1,172−9.8% | 減碼 |
| Mirae Asset Global ETFs Holdings Ltd. | 10,193 | $34.1 萬 | 0.00% | +172+1.7% | 加碼 |
| Legal & General Group Plc | 10,062 | $33.7 萬 | 0.00% | +4,327+75.4% | 加碼 |
| Massachusetts Financial Services Co | 9,982 | $33.4 萬 | 0.00% | −400−3.9% | 減碼 |
| Gotham Asset Management, LLC | 9,322 | $31.2 萬 | 0.00% | +9,322 | 新進 |
| Virtus Investment Advisers, Inc. | 9,102 | $30.5 萬 | 0.07% | −1,617−15.1% | 減碼 |
| Canada Pension Plan Investment Board | 8,900 | $29.8 萬 | 0.00% | +8,900 | 新進 |
| New York State Common Retirement Fund | 8,500 | $28.5 萬 | 0.00% | +2,900+51.8% | 加碼 |
| First Trust Advisors LP | 7,739 | $25.9 萬 | 0.00% | +7,739 | 新進 |