Septerna, Inc.
SEPN- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001984086
近 90 天，Septerna, Inc. 內部人申報 0 筆公開市場買進、7 筆賣出；2026 年第 2 季末有 153 家機構在 13F 申報持有，市值合計 $15.8 億；沒有大師持有。
2025 年第 4 季 13F 持有人
Septerna, Inc. 在 2025/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 122
- 較 2025 年第 3 季 +40 家
- 持有股數
- 4,559 萬
- 較 2025 年第 3 季 +103.9 萬 (+2.3%)
- 總市值
- $12.7 億
- 較 2025 年第 3 季 +$4.33 億 (+51.7%)
- 新進機構
- 45
- 另有 31 家加碼
- 清倉機構
- 5
- 另有 27 家減碼
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 SEPN 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 153 | $15.8 億 |
| 2026 年第 1 季 | 124 | $11.0 億 |
| 2025 年第 4 季 | 122 | $12.7 億 |
| 2025 年第 3 季 | 82 | $8.38 億 |
| 2025 年第 2 季 | 89 | $4.70 億 |
| 2025 年第 1 季 | 71 | $2.62 億 |
| 2024 年第 4 季 | 71 | $10.1 億 |
| 2024 年第 3 季 | 0 | $0 |
| 2024 年第 2 季 | 0 | $0 |
| 2024 年第 1 季 | 0 | $0 |
| 2023 年第 4 季 | 0 | $0 |
| 2023 年第 3 季 | 0 | $0 |
| 2023 年第 2 季 | 0 | $0 |
| 2023 年第 1 季 | 0 | $0 |
| 2022 年第 4 季 | 0 | $0 |
| 2022 年第 3 季 | 0 | $0 |
| 2022 年第 2 季 | 0 | $0 |
| 2022 年第 1 季 | 0 | $0 |
| 2021 年第 4 季 | 0 | $0 |
| 2021 年第 3 季 | 0 | $0 |
| 2021 年第 2 季 | 0 | $0 |
| 2021 年第 1 季 | 0 | $0 |
2025 年第 4 季持有機構
每家機構持有 Septerna, Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 6,995,858 | $1.95 億 | 2.00% | 00.0% | 不變 |
| TRV GP V, LLC | 6,215,591 | $1.73 億 | 40.38% | 00.0% | 不變 |
| Driehaus Capital Management LLC | 4,809,470 | $1.34 億 | 0.91% | −110,426−2.2% | 減碼 |
| TRV GP VI, LLC | 4,211,659 | $1.17 億 | 79.05% | 00.0% | 不變 |
| Samsara BioCapital, LLC | 3,149,128 | $8,780 萬 | 9.06% | 00.0% | 不變 |
| Goldman Sachs Group Inc | 2,715,129 | $7,570 萬 | 0.01% | +1,260,409+86.6% | 加碼 |
| Siren, L.L.C. | 2,000,000 | $5,576 萬 | 1.66% | −202,514−9.2% | 減碼 |
| BlackRock, Inc. | 1,801,328 | $5,022 萬 | 0.00% | +341,533+23.4% | 加碼 |
| BVF Inc | 1,720,782 | $4,798 萬 | 1.61% | −2,295,008−57.1% | 減碼 |
| Vanguard Group Inc | 1,508,195 | $4,205 萬 | 0.00% | −10,562−0.7% | 減碼 |
| Avoro Capital Advisors LLC | 1,337,500 | $3,729 萬 | 0.37% | 00.0% | 不變 |
| ADAR1 Capital Management, LLC | 1,157,611 | $3,227 萬 | 2.41% | −18,880−1.6% | 減碼 |
| First Light Asset Management, LLC | 620,811 | $1,731 萬 | 1.32% | +620,811 | 新進 |
| VR Adviser, LLC | 610,808 | $1,703 萬 | 0.84% | 00.0% | 不變 |
| Geode Capital Management, LLC | 572,734 | $1,597 萬 | 0.00% | +27,033+5.0% | 加碼 |
| Casdin Capital, LLC | 553,268 | $1,543 萬 | 0.96% | 00.0% | 不變 |
| Primecap Management Co | 546,100 | $1,523 萬 | 0.01% | +546,100 | 新進 |
| State Street Corp | 540,028 | $1,506 萬 | 0.00% | +121,068+28.9% | 加碼 |
| Perceptive Advisors LLC | 433,160 | $1,208 萬 | 0.22% | −108,290−20.0% | 減碼 |
| Woodline Partners LP | 385,310 | $1,074 萬 | 0.04% | +102,725+36.4% | 加碼 |
| Soleus Capital Management, L.P. | 383,368 | $1,069 萬 | 0.45% | +365,108+1,999.5% | 加碼 |
| Catalio Capital Management, LP | 294,360 | $820.7 萬 | 1.45% | 00.0% | 不變 |
| Marshall Wace, LLP | 226,901 | $632.6 萬 | 0.01% | +226,901 | 新進 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 222,702 | $620.9 萬 | 0.01% | 00.0% | 不變 |
| Kalehua Capital Management LLC | 194,544 | $542.4 萬 | 5.36% | +194,544 | 新進 |
| Charles Schwab Investment Management Inc | 187,241 | $522.0 萬 | 0.00% | +337+0.2% | 加碼 |
| Invesco Ltd. | 162,014 | $451.7 萬 | 0.00% | −15,056−8.5% | 減碼 |
| Northern Trust Corp | 154,196 | $429.9 萬 | 0.00% | −13,149−7.9% | 減碼 |
| Millennium Management LLC | 107,463 | $299.6 萬 | 0.00% | −276,737−72.0% | 減碼 |
| Morgan Stanley | 103,985 | $289.9 萬 | 0.00% | +49,527+90.9% | 加碼 |
| Two Sigma Investments, LP | 92,809 | $258.8 萬 | 0.00% | +475+0.5% | 加碼 |
| Federated Hermes, Inc. | 78,905 | $220.0 萬 | 0.00% | +78,905 | 新進 |
| HighVista Strategies LLC | 78,682 | $219.4 萬 | 0.56% | +78,682 | 新進 |
| Citadel Advisors LLC | 75,945 | $211.7 萬 | 0.00% | +75,945 | 新進 |
| UBS Group AG | 68,817 | $191.9 萬 | 0.00% | +9,771+16.5% | 加碼 |
| JPMorgan Chase & Co | 68,338 | $190.5 萬 | 0.00% | +59,602+682.3% | 加碼 |
| Rangeley Capital, LLC | 65,800 | $183.5 萬 | 1.58% | −22,200−25.2% | 減碼 |
| Jacobs Levy Equity Management, Inc | 61,370 | $171.1 萬 | 0.01% | +25,592+71.5% | 加碼 |
| Bank of New York Mellon Corp | 55,332 | $154.3 萬 | 0.00% | +3,701+7.2% | 加碼 |
| American Century Companies Inc | 50,689 | $141.3 萬 | 0.00% | +25,406+100.5% | 加碼 |
| Longaeva Partners L.P. | 49,902 | $139.1 萬 | 0.17% | −7,162−12.6% | 減碼 |
| Numerai GP LLC | 45,866 | $127.9 萬 | 0.15% | +45,866 | 新進 |
| Jane Street Group, LLC | 44,070 | $122.9 萬 | 0.00% | +44,070 | 新進 |
| Trexquant Investment LP | 44,005 | $122.7 萬 | 0.01% | +44,005 | 新進 |
| Barclays PLC | 38,147 | $106.4 萬 | 0.00% | +8,045+26.7% | 加碼 |
| ExodusPoint Capital Management, LP | 37,867 | $105.6 萬 | 0.01% | +37,867 | 新進 |
| Bank of America Corp | 37,594 | $104.8 萬 | 0.00% | −13,901−27.0% | 減碼 |
| Alyeska Investment Group, L.P. | 35,000 | $97.6 萬 | 0.00% | 00.0% | 不變 |
| Algert Global LLC | 34,944 | $97.4 萬 | 0.02% | +34,944 | 新進 |
| Acadian Asset Management LLC | 30,877 | $85.8 萬 | 0.00% | +30,877 | 新進 |
| Wells Fargo & Company | 26,529 | $74.0 萬 | 0.00% | +6,382+31.7% | 加碼 |
| Rhumbline Advisers | 26,419 | $73.7 萬 | 0.00% | −1,185−4.3% | 減碼 |
| Nuveen, LLC | 25,798 | $71.9 萬 | 0.00% | +1,837+7.7% | 加碼 |
| Two Sigma Advisers, LP | 25,700 | $71.7 萬 | 0.00% | +5,000+24.2% | 加碼 |
| Price T Rowe Associates Inc | 25,443 | $71.0 萬 | 0.00% | −1,981−7.2% | 減碼 |
| Logos Global Management LP | 23,548 | $65.7 萬 | 0.04% | −60,000−71.8% | 減碼 |
| XTX Topco Ltd | 23,315 | $65.0 萬 | 0.02% | +23,315 | 新進 |
| VARCOV Co. | 22,634 | $63.1 萬 | 0.25% | +22,634 | 新進 |
| Alliancebernstein L.P. | 19,600 | $54.6 萬 | 0.00% | −2,500−11.3% | 減碼 |
| Tudor Investment Corp Et Al | 18,053 | $50.3 萬 | 0.00% | +18,053 | 新進 |
| Franklin Resources Inc | 16,852 | $47.0 萬 | 0.00% | +16,852 | 新進 |
| Russell Investments Group, Ltd. | 15,310 | $42.7 萬 | 0.00% | +13,414+707.5% | 加碼 |
| Deutsche Bank AG | 14,879 | $41.5 萬 | 0.00% | +744+5.3% | 加碼 |
| Squarepoint Ops LLC | 14,847 | $41.4 萬 | 0.00% | +14,847 | 新進 |
| STRS Ohio | 14,600 | $40.7 萬 | 0.00% | +14,600 | 新進 |
| Los Angeles Capital Management LLC | 18,550 | $39.9 萬 | 0.00% | +18,550 | 新進 |
| Ameriprise Financial Inc | 14,090 | $39.3 萬 | 0.00% | +14,090 | 新進 |
| MetLife Investment Management | 13,685 | $38.2 萬 | 0.00% | 00.0% | 不變 |
| Intech Investment Management LLC | 13,283 | $37.0 萬 | 0.00% | +13,283 | 新進 |
| Advisor Group Holdings, Inc. | 12,693 | $35.4 萬 | 0.00% | −170−1.3% | 減碼 |
| Seven Fleet Capital Management LP | 11,445 | $31.9 萬 | 0.22% | +11,445 | 新進 |
| Dynamic Technology Lab Private Ltd | 10,810 | $30.1 萬 | 0.07% | +10,810 | 新進 |
| PharVision Advisers, LLC | 10,739 | $29.9 萬 | 0.15% | −1,193−10.0% | 減碼 |
| Public Employees Retirement System of Ohio | 10,594 | $29.5 萬 | 0.00% | +10,594 | 新進 |
| Virtus Investment Advisers, Inc. | 10,457 | $29.2 萬 | 0.08% | +10,457 | 新進 |
| China Universal Asset Management Co., Ltd. | 10,296 | $28.7 萬 | 0.02% | +10,296 | 新進 |
| Baader Bank INC | 10,000 | $27.9 萬 | 0.02% | +10,000 | 新進 |
| Mirae Asset Global ETFs Holdings Ltd. | 9,934 | $27.7 萬 | 0.00% | +143+1.5% | 加碼 |
| Atom Investors LP | 9,791 | $27.3 萬 | 0.02% | +9,791 | 新進 |
| Citigroup Inc | 9,561 | $26.7 萬 | 0.00% | +9,312+3,739.8% | 加碼 |
| Graham Capital Management, L.P. | 8,971 | $25.0 萬 | 0.01% | +8,971 | 新進 |
| Jump Financial, LLC | 8,399 | $23.4 萬 | 0.00% | +8,399 | 新進 |
| Bank of Nova Scotia | 8,300 | $23.1 萬 | 0.00% | +8,300 | 新進 |
| AQR Capital Management LLC | 7,826 | $21.8 萬 | 0.00% | +7,826 | 新進 |
| New York State Common Retirement Fund | 5,600 | $15.6 萬 | 0.00% | +2,700+93.1% | 加碼 |
| BNP Paribas Arbitrage, SA | 5,449 | $15.2 萬 | 0.00% | +1,294+31.1% | 加碼 |
| Police & Firemen's Retirement System of New Jersey | 5,175 | $14.4 萬 | 0.00% | 00.0% | 不變 |
| Balyasny Asset Management LLC | 3,571 | $9.96 萬 | 0.00% | +3,571 | 新進 |
| FMR LLC | 3,307 | $9.22 萬 | 0.00% | −131−3.8% | 減碼 |
| Caitong International Asset Management Co., Ltd | 3,170 | $8.84 萬 | 0.02% | +3,170 | 新進 |
| Mirae Asset Global Investments Co., Ltd. | 2,176 | $6.07 萬 | 0.00% | +2,176 | 新進 |
| Tower Research Capital LLC (TRC) | 2,156 | $6.01 萬 | 0.00% | +1,197+124.8% | 加碼 |
| Ameritas Investment Partners, Inc. | 1,944 | $5.42 萬 | 0.00% | 00.0% | 不變 |
| Legal & General Group Plc | 1,945 | $5.42 萬 | 0.00% | 00.0% | 不變 |
| Covestor Ltd | 1,941 | $5.40 萬 | 0.03% | −1,679−46.4% | 減碼 |
| California State Teachers Retirement System | 1,316 | $3.67 萬 | 0.00% | −55−4.0% | 減碼 |
| Global Retirement Partners, LLC | 1,256 | $3.50 萬 | 0.00% | +1,256 | 新進 |
| Sterling Capital Management LLC | 1,232 | $3.43 萬 | 0.00% | −243−16.5% | 減碼 |
| Signaturefd, LLC | 989 | $2.76 萬 | 0.00% | +23+2.4% | 加碼 |
| Group One Trading, L.P. | 944 | $2.63 萬 | 0.00% | −745−44.1% | 減碼 |