Denali Therapeutics Inc.
DNLI- 交易所
- Nasdaq
- 產業
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
近 90 天，Denali Therapeutics Inc. 內部人申報 0 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 294 家機構在 13F 申報持有，市值合計 $40.0 億；沒有大師持有。
2025 年第 4 季 13F 持有人
Denali Therapeutics Inc. 在 2025/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 250
- 較 2025 年第 3 季 +17 家
- 持有股數
- 1.51 億
- 較 2025 年第 3 季 +1,619 萬 (+12.0%)
- 總市值
- $25.0 億
- 較 2025 年第 3 季 +$5.36 億 (+27.4%)
- 新進機構
- 51
- 另有 86 家加碼
- 清倉機構
- 34
- 另有 71 家減碼
另有 7 家機構在 2025 年第 3 季持有、還沒有申報 2025 年第 4 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 DNLI 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 294 | $40.0 億 |
| 2026 年第 1 季 | 269 | $28.2 億 |
| 2025 年第 4 季 | 250 | $25.0 億 |
| 2025 年第 3 季 | 240 | $19.7 億 |
| 2025 年第 2 季 | 231 | $19.3 億 |
| 2025 年第 1 季 | 222 | $18.5 億 |
| 2024 年第 4 季 | 224 | $26.1 億 |
| 2024 年第 3 季 | 217 | $36.9 億 |
| 2024 年第 2 季 | 203 | $28.8 億 |
| 2024 年第 1 季 | 211 | $25.1 億 |
| 2023 年第 4 季 | 209 | $24.7 億 |
| 2023 年第 3 季 | 195 | $22.4 億 |
| 2023 年第 2 季 | 203 | $31.8 億 |
| 2023 年第 1 季 | 202 | $24.9 億 |
| 2022 年第 4 季 | 199 | $29.4 億 |
| 2022 年第 3 季 | 200 | $28.4 億 |
| 2022 年第 2 季 | 188 | $27.3 億 |
| 2022 年第 1 季 | 190 | $27.9 億 |
| 2021 年第 4 季 | 213 | $38.0 億 |
| 2021 年第 3 季 | 214 | $42.8 億 |
| 2021 年第 2 季 | 210 | $63.2 億 |
| 2021 年第 1 季 | 218 | $46.0 億 |
2025 年第 4 季持有機構
每家機構持有 Denali Therapeutics Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Two Sigma Investments, LP | 430,177 | $710.2 萬 | 0.01% | +163,885+61.5% | 加碼 |
| Schroder Investment Management Group | 450,985 | $740.1 萬 | 0.01% | +241,390+115.2% | 加碼 |
| Hudson Bay Capital Management LP | 450,000 | $743.0 萬 | 0.04% | +145,000+47.5% | 加碼 |
| Vestal Point Capital, LP | 465,000 | $767.7 萬 | 0.28% | +465,000 | 新進 |
| Ensign Peak Advisors, Inc | 515,721 | $851.5 萬 | 0.02% | −18,350−3.4% | 減碼 |
| Segall Bryant & Hamill, LLC | 537,000 | $886.6 萬 | 0.12% | +24,042+4.7% | 加碼 |
| Qube Research & Technologies Ltd | 590,314 | $974.6 萬 | 0.01% | +362,324+158.9% | 加碼 |
| Voloridge Investment Management, LLC | 591,461 | $976.5 萬 | 0.03% | −344,769−36.8% | 減碼 |
| Cercano Management LLC | 625,000 | $1,032 萬 | 0.39% | 00.0% | 不變 |
| Palo Alto Investors LP | 641,239 | $1,059 萬 | 1.47% | +233,233+57.2% | 加碼 |
| Defilade Capital Management, L.P. | 656,713 | $1,084 萬 | 1.47% | +656,713 | 新進 |
| Bank of New York Mellon Corp | 762,087 | $1,258 萬 | 0.00% | −38,660−4.8% | 減碼 |
| Marshall Wace, LLP | 763,892 | $1,261 萬 | 0.01% | −23,137−2.9% | 減碼 |
| Citadel Advisors LLC | 779,148 | $1,286 萬 | 0.01% | +90,924+13.2% | 加碼 |
| Alyeska Investment Group, L.P. | 859,108 | $1,418 萬 | 0.04% | +859,108 | 新進 |
| Bank of America Corp | 932,144 | $1,539 萬 | 0.00% | −28,994−3.0% | 減碼 |
| Foresite Capital Management VI LLC | 1,000,000 | $1,651 萬 | 4.99% | 00.0% | 不變 |
| Masters Capital Management LLC | 1,000,000 | $1,651 萬 | 2.28% | +250,000+33.3% | 加碼 |
| ExodusPoint Capital Management, LP | 1,023,253 | $1,689 萬 | 0.19% | +1,023,253 | 新進 |
| Candriam Luxembourg S.C.A. | 1,166,379 | $1,926 萬 | 0.10% | +332,797+39.9% | 加碼 |
| Northern Trust Corp | 1,199,744 | $1,981 萬 | 0.00% | −34,435−2.8% | 減碼 |
| Charles Schwab Investment Management Inc | 1,200,475 | $1,982 萬 | 0.00% | +49,091+4.3% | 加碼 |
| Morgan Stanley | 1,219,854 | $2,014 萬 | 0.00% | −469,638−27.8% | 減碼 |
| Pictet Asset Management Holding SA | 1,329,108 | $2,198 萬 | 0.02% | +829,946+166.3% | 加碼 |
| Siren, L.L.C. | 1,396,513 | $2,306 萬 | 0.69% | +575,000+70.0% | 加碼 |
| Principal Financial Group Inc | 1,524,123 | $2,516 萬 | 0.01% | +252,933+19.9% | 加碼 |
| Point72 Asset Management, L.P. | 1,700,000 | $2,807 萬 | 0.04% | −819,535−32.5% | 減碼 |
| Lynx1 Capital Management LP | 1,738,750 | $2,871 萬 | 5.81% | +1,477,063+564.4% | 加碼 |
| Casdin Capital, LLC | 1,840,000 | $3,038 萬 | 1.89% | +950,000+106.7% | 加碼 |
| Standard Life Aberdeen plc | 2,032,967 | $3,356 萬 | 0.05% | +919,381+82.6% | 加碼 |
| Dimensional Fund Advisors LP | 2,374,303 | $3,920 萬 | 0.01% | +17,089+0.7% | 加碼 |
| UBS Group AG | 2,404,704 | $3,970 萬 | 0.01% | +392,351+19.5% | 加碼 |
| Fisher Asset Management, LLC | 2,589,403 | $4,275 萬 | 0.01% | +957,907+58.7% | 加碼 |
| Crestline Management, LP | 2,810,732 | $4,641 萬 | 87.02% | −600,000−17.6% | 減碼 |
| Holocene Advisors, LP | 3,152,734 | $5,205 萬 | 0.11% | +17,022+0.5% | 加碼 |
| Geode Capital Management, LLC | 3,458,131 | $5,710 萬 | 0.00% | −7,926−0.2% | 減碼 |
| Alliancebernstein L.P. | 3,557,935 | $5,874 萬 | 0.02% | +37,521+1.1% | 加碼 |
| Capital Research Global Investors | 3,729,244 | $6,157 萬 | 0.01% | −1,031,614−21.7% | 減碼 |
| Baker Bros. Advisors LP | 3,731,695 | $6,161 萬 | 0.36% | 00.0% | 不變 |
| Goldman Sachs Group Inc | 3,835,803 | $6,333 萬 | 0.01% | +1,672,098+77.3% | 加碼 |
| Price T Rowe Associates Inc | 3,915,951 | $6,465 萬 | 0.01% | −652,417−14.3% | 減碼 |
| UBS Asset Management Americas Inc | 4,983,726 | $8,228 萬 | 0.02% | −481,311−8.8% | 減碼 |
| Norges Bank | 5,119,622 | $8,452 萬 | 0.01% | +5,119,622 | 新進 |
| FMR LLC | 6,097,211 | $1.01 億 | 0.01% | −243,105−3.8% | 減碼 |
| State Street Corp | 6,263,371 | $1.03 億 | 0.00% | +799,110+14.6% | 加碼 |
| Temasek Holdings (Private) Ltd | 7,012,974 | $1.16 億 | 0.37% | +1,657,142+30.9% | 加碼 |
| T. Rowe Price Investment Management, Inc. | 7,254,132 | $1.20 億 | 0.08% | +1,615,565+28.7% | 加碼 |
| Baillie Gifford & Co | 12,310,889 | $2.03 億 | 0.17% | +719,304+6.2% | 加碼 |
| BlackRock, Inc. | 12,715,201 | $2.10 億 | 0.00% | +425,575+3.5% | 加碼 |
| Vanguard Group Inc | 13,057,890 | $2.16 億 | 0.00% | +1,064,972+8.9% | 加碼 |
| Yiheng Capital Management, L.P. | 0 | $0 | 0.00% | −469,981−100.0% | 清倉 |
| Pier Capital, LLC | 0 | $0 | 0.00% | −301,171−100.0% | 清倉 |
| Boxer Capital Management, LLC | 0 | $0 | 0.00% | −250,000−100.0% | 清倉 |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −226,203−100.0% | 清倉 |
| Campbell & CO Investment Adviser LLC | 0 | $0 | 0.00% | −216,774−100.0% | 清倉 |
| Edgestream Partners, L.P. | 0 | $0 | 0.00% | −123,819−100.0% | 清倉 |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −80,518−100.0% | 清倉 |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −69,216−100.0% | 清倉 |
| XTX Topco Ltd | 0 | $0 | 0.00% | −65,345−100.0% | 清倉 |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −56,237−100.0% | 清倉 |
| Jacobs Levy Equity Management, Inc | 0 | $0 | 0.00% | −45,969−100.0% | 清倉 |
| Jennison Associates LLC | 0 | $0 | 0.00% | −45,445−100.0% | 清倉 |
| Cantor Fitzgerald, L. P. | 0 | $0 | 0.00% | −45,000−100.0% | 清倉 |
| Cinctive Capital Management LP | 0 | $0 | 0.00% | −27,792−100.0% | 清倉 |
| EntryPoint Capital, LLC | 0 | $0 | 0.00% | −24,058−100.0% | 清倉 |
| Oxford Asset Management LLP | 0 | $0 | 0.00% | −22,231−100.0% | 清倉 |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −17,629−100.0% | 清倉 |
| Jain Global LLC | 0 | $0 | 0.00% | −17,414−100.0% | 清倉 |
| Prudential Financial Inc | 0 | $0 | 0.00% | −16,938−100.0% | 清倉 |
| HSBC Holdings PLC | 0 | $0 | 0.00% | −14,004−100.0% | 清倉 |
| MONECO Advisors, LLC | 0 | $0 | 0.00% | −12,478−100.0% | 清倉 |
| Aigen Investment Management, LP | 0 | $0 | 0.00% | −12,075−100.0% | 清倉 |
| Caption Management, LLC | 0 | $0 | 0.00% | −7,366−100.0% | 清倉 |
| Caitong International Asset Management Co., Ltd | 0 | $0 | 0.00% | −1,528−100.0% | 清倉 |
| Groupe la Francaise | 0 | $0 | 0.00% | −620−100.0% | 清倉 |
| Meeder Asset Management Inc | 0 | $0 | 0.00% | −206−100.0% | 清倉 |
| Halbert Hargrove Global Advisors, LLC | 0 | $0 | 0.00% | −104−100.0% | 清倉 |
| Harbour Investments, Inc. | 0 | $0 | 0.00% | −100−100.0% | 清倉 |
| Rise Advisors, LLC | 0 | $0 | 0.00% | −74−100.0% | 清倉 |
| National Bank of Canada | 0 | $0 | 0.00% | −50−100.0% | 清倉 |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −39−100.0% | 清倉 |
| Truvestments Capital LLC | 0 | $0 | 0.00% | −1−100.0% | 清倉 |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −41−100.0% | 清倉 |
| Cloud Capital Management, LLC | 0 | $0 | 0.00% | −2−100.0% | 清倉 |
| AXA Investment Managers S.A. | – | – | – | – | 本季未申報 |
| Cubist Systematic Strategies, LLC | – | – | – | – | 本季未申報 |
| CIBC Bancorp USA Inc. | – | – | – | – | 本季未申報 |
| Shell Asset Management Co | – | – | – | – | 本季未申報 |
| Guerra Advisors Inc | – | – | – | – | 本季未申報 |
| Point72 (DIFC) Ltd | – | – | – | – | 本季未申報 |
| Hemington Wealth Management | – | – | – | – | 本季未申報 |