Apellis Pharmaceuticals, Inc.
APLS2026/5/14 下市- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. 已在 2026/5/14 下市；內部人最後一份 Form 4 在 2026/5/14 申報；2026 年第 1 季末有 324 家機構在 13F 申報持有，市值合計 $55.6 億；大師中只有索羅斯基金管理持有。
2025 年第 4 季 13F 持有人
Apellis Pharmaceuticals, Inc. 在 2025/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 280
- 較 2025 年第 3 季 +14 家
- 持有股數
- 1.26 億
- 較 2025 年第 3 季 +464.5 萬 (+3.8%)
- 總市值
- $31.7 億
- 較 2025 年第 3 季 +$4.15 億 (+15.0%)
- 新進機構
- 61
- 另有 89 家加碼
- 清倉機構
- 47
- 另有 102 家減碼
另有 7 家機構在 2025 年第 3 季持有、還沒有申報 2025 年第 4 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 APLS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 1 | $1.02 萬 |
| 2026 年第 1 季 | 324 | $55.6 億 |
| 2025 年第 4 季 | 280 | $31.7 億 |
| 2025 年第 3 季 | 273 | $27.7 億 |
| 2025 年第 2 季 | 247 | $22.8 億 |
| 2025 年第 1 季 | 255 | $28.0 億 |
| 2024 年第 4 季 | 260 | $40.4 億 |
| 2024 年第 3 季 | 265 | $34.1 億 |
| 2024 年第 2 季 | 263 | $44.3 億 |
| 2024 年第 1 季 | 302 | $66.5 億 |
| 2023 年第 4 季 | 284 | $68.2 億 |
| 2023 年第 3 季 | 256 | $43.4 億 |
| 2023 年第 2 季 | 317 | $97.1 億 |
| 2023 年第 1 季 | 282 | $72.8 億 |
| 2022 年第 4 季 | 244 | $52.0 億 |
| 2022 年第 3 季 | 250 | $66.6 億 |
| 2022 年第 2 季 | 212 | $41.5 億 |
| 2022 年第 1 季 | 212 | $46.2 億 |
| 2021 年第 4 季 | 187 | $38.3 億 |
| 2021 年第 3 季 | 181 | $22.9 億 |
| 2021 年第 2 季 | 205 | $40.8 億 |
| 2021 年第 1 季 | 175 | $28.0 億 |
2025 年第 4 季持有機構
每家機構持有 Apellis Pharmaceuticals, Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Swiss Life Asset Management Ltd | 10,832 | $27.2 萬 | 0.00% | +10,832 | 新進 |
| Teacher Retirement System of Texas | 11,225 | $28.2 萬 | 0.00% | −7,287−39.4% | 減碼 |
| Franklin Resources Inc | 11,304 | $28.4 萬 | 0.00% | +11,304 | 新進 |
| Bridgefront Capital, LLC | 11,326 | $28.5 萬 | 0.07% | +11,326 | 新進 |
| Quest Partners LLC | 11,741 | $29.5 萬 | 0.02% | −11,358−49.2% | 減碼 |
| Wedmont Private Capital | 11,883 | $31.5 萬 | 0.01% | +468+4.1% | 加碼 |
| Freestone Grove Partners LP | 12,537 | $31.5 萬 | 0.00% | +12,537 | 新進 |
| Walleye Trading LLC | 12,699 | $31.9 萬 | 0.01% | +2,258+21.6% | 加碼 |
| Twinbeech Capital LP | 13,152 | $33.0 萬 | 0.02% | +4,225+47.3% | 加碼 |
| Empowered Funds, LLC | 13,381 | $33.6 萬 | 0.01% | +40+0.3% | 加碼 |
| Summit Trail Advisors, LLC | 13,851 | $34.8 萬 | 0.01% | +3,575+34.8% | 加碼 |
| Pallas Capital Advisors LLC | 13,885 | $34.9 萬 | 0.01% | −19,192−58.0% | 減碼 |
| Birchview Capital, LP | 14,000 | $35.2 萬 | 0.21% | 00.0% | 不變 |
| Nomura Holdings Inc | 14,200 | $35.7 萬 | 0.00% | −22,400−61.2% | 減碼 |
| M&T Bank Corp | 14,477 | $36.4 萬 | 0.00% | +1,452+11.1% | 加碼 |
| GWM Advisors LLC | 14,570 | $36.6 萬 | 0.00% | +14,570 | 新進 |
| Maven Securities LTD | 15,000 | $37.7 萬 | 0.05% | +15,000 | 新進 |
| Victory Capital Management Inc | 15,197 | $38.2 萬 | 0.00% | −75−0.5% | 減碼 |
| Vident Advisory, LLC | 15,553 | $39.1 萬 | 0.00% | −19,828−56.0% | 減碼 |
| Duncan Williams Asset Management, LLC | 17,005 | $39.4 萬 | 0.10% | 00.0% | 不變 |
| Brevan Howard Capital Management LP | 16,117 | $40.5 萬 | 0.01% | −74,904−82.3% | 減碼 |
| KLP Kapitalforvaltning AS | 16,200 | $40.7 萬 | 0.00% | +600+3.8% | 加碼 |
| Creative Planning | 16,439 | $41.3 萬 | 0.00% | −19,206−53.9% | 減碼 |
| Jain Global LLC | 16,877 | $42.4 萬 | 0.00% | +16,877 | 新進 |
| Allianz Asset Management GmbH | 17,000 | $42.7 萬 | 0.00% | 00.0% | 不變 |
| Mercer Global Advisors Inc | 17,668 | $44.4 萬 | 0.00% | −21,375−54.7% | 減碼 |
| Advent Capital Management | 18,000 | $45.2 萬 | 0.01% | +18,000 | 新進 |
| Xponance, Inc. | 18,164 | $45.6 萬 | 0.00% | +681+3.9% | 加碼 |
| Qube Research & Technologies Ltd | 18,843 | $47.3 萬 | 0.00% | −101,160−84.3% | 減碼 |
| Diversified Trust Co | 18,942 | $47.6 萬 | 0.01% | +18,942 | 新進 |
| Odyssean, LLC | 19,207 | $48.2 萬 | 0.35% | +19,207 | 新進 |
| ADAR1 Capital Management, LLC | 20,000 | $50.2 萬 | 0.04% | 00.0% | 不變 |
| China Universal Asset Management Co., Ltd. | 20,617 | $51.8 萬 | 0.04% | −1,520−6.9% | 減碼 |
| Arizona State Retirement System | 21,010 | $52.8 萬 | 0.00% | −1,288−5.8% | 減碼 |
| IMC-Chicago, LLC | 21,324 | $53.6 萬 | 0.01% | +21,324 | 新進 |
| Boothbay Fund Management, LLC | 21,415 | $53.8 萬 | 0.01% | −157,811−88.1% | 減碼 |
| PSP Research LLC | 21,866 | $54.9 萬 | 0.48% | +21,866 | 新進 |
| Manufacturers Life Insurance Company, The | 22,852 | $57.4 萬 | 0.00% | +143+0.6% | 加碼 |
| Marex Group plc | 23,000 | $57.8 萬 | 0.01% | +23,000 | 新進 |
| Entropy Technologies, LP | 23,128 | $58.1 萬 | 0.03% | −1,475−6.0% | 減碼 |
| Cerity Partners LLC | 23,971 | $60.2 萬 | 0.00% | −104,139−81.3% | 減碼 |
| Quadrature Capital Ltd | 24,075 | $60.5 萬 | 0.01% | +24,075 | 新進 |
| Virginia Retirement Systems Et Al | 24,365 | $61.2 萬 | 0.00% | −1,100−4.3% | 減碼 |
| Erste Asset Management GmbH | 25,300 | $63.7 萬 | 0.01% | 00.0% | 不變 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 25,364 | $63.7 萬 | 0.00% | +4,047+19.0% | 加碼 |
| Ieq Capital, LLC | 25,500 | $64.1 萬 | 0.00% | −271,284−91.4% | 減碼 |
| State of New Jersey Common Pension Fund D | 25,863 | $65.0 萬 | 0.00% | +25,863 | 新進 |
| Virtus Investment Advisers, Inc. | 27,086 | $68.0 萬 | 0.18% | +4,013+17.4% | 加碼 |
| Simplex Trading, LLC | 27,187 | $68.3 萬 | 0.02% | −26,714−49.6% | 減碼 |
| Wealth Enhancement Advisory Services, LLC | 30,175 | $72.2 萬 | 0.00% | −47,333−61.1% | 減碼 |
| Amundi | 30,721 | $77.2 萬 | 0.00% | −1,462,957−97.9% | 減碼 |
| Dark Forest Capital Management LP | 31,091 | $78.1 萬 | 0.04% | +31,091 | 新進 |
| Y-Intercept (Hong Kong) Ltd | 31,581 | $79.3 萬 | 0.02% | −132,232−80.7% | 減碼 |
| Quantinno Capital Management LP | 31,763 | $79.8 萬 | 0.00% | −16,656−34.4% | 減碼 |
| FMR LLC | 32,163 | $80.8 萬 | 0.00% | +13,660+73.8% | 加碼 |
| Public Employees Retirement System of Ohio | 32,448 | $81.5 萬 | 0.00% | −1,231−3.7% | 減碼 |
| Vontobel Holding Ltd. | 34,039 | $85.5 萬 | 0.00% | +34,039 | 新進 |
| Alliancebernstein L.P. | 34,530 | $86.7 萬 | 0.00% | −46,075−57.2% | 減碼 |
| Handelsbanken Fonder AB | 35,400 | $88.9 萬 | 0.00% | −3,700−9.5% | 減碼 |
| Guggenheim Capital LLC | 36,647 | $92.1 萬 | 0.01% | +2,813+8.3% | 加碼 |
| Stifel Financial Corp | 36,661 | $92.1 萬 | 0.00% | +36,661 | 新進 |
| Prelude Capital Management, LLC | 38,521 | $96.8 萬 | 0.07% | +38,521 | 新進 |
| CWM, LLC | 41,880 | $105.2 萬 | 0.00% | −52,353−55.6% | 減碼 |
| Panagora Asset Management Inc | 42,134 | $105.8 萬 | 0.00% | +42,134 | 新進 |
| Voya Investment Management LLC | 43,661 | $109.7 萬 | 0.00% | −129,273−74.8% | 減碼 |
| Treasurer of the State of North Carolina | 45,170 | $113.5 萬 | 0.00% | −3,296−6.8% | 減碼 |
| Police & Firemen's Retirement System of New Jersey | 46,009 | $115.6 萬 | 0.01% | −2,361−4.9% | 減碼 |
| Elmind Capital, LP | 50,000 | $125.6 萬 | 0.37% | +50,000 | 新進 |
| Ishara Investments LP | 50,000 | $125.6 萬 | 1.46% | +50,000 | 新進 |
| Jane Street Group, LLC | 50,114 | $125.9 萬 | 0.00% | −243,085−82.9% | 減碼 |
| Hennion & Walsh Asset Management, Inc. | 51,933 | $130.5 萬 | 0.05% | +3,804+7.9% | 加碼 |
| The PNC Financial Services Group, Inc. | 53,526 | $134.5 萬 | 0.00% | −526−1.0% | 減碼 |
| PDT Partners, LLC | 53,951 | $135.5 萬 | 0.09% | 00.0% | 不變 |
| SEI Investments Co | 60,291 | $151.5 萬 | 0.00% | −94,831−61.1% | 減碼 |
| Profund Advisors LLC | 61,832 | $155.3 萬 | 0.05% | +27,120+78.1% | 加碼 |
| Balyasny Asset Management LLC | 65,133 | $163.6 萬 | 0.00% | +65,133 | 新進 |
| State of Wisconsin Investment Board | 66,916 | $168.1 萬 | 0.00% | −18,845−22.0% | 減碼 |
| Raymond James Financial Inc | 66,997 | $168.3 萬 | 0.00% | −10,681−13.8% | 減碼 |
| Ikarian Capital, LLC | 71,747 | $180.2 萬 | 0.23% | −380,155−84.1% | 減碼 |
| California State Teachers Retirement System | 73,203 | $183.9 萬 | 0.00% | −95−0.1% | 減碼 |
| Coppell Advisory Solutions LLC | 77,390 | $195.3 萬 | 0.20% | +77,390 | 新進 |
| Steward Partners Investment Advisory, LLC | 81,698 | $205.2 萬 | 0.01% | −32,390−28.4% | 減碼 |
| Legal & General Group Plc | 85,489 | $214.7 萬 | 0.00% | −6,903−7.5% | 減碼 |
| Winton Group Ltd | 86,653 | $217.7 萬 | 0.08% | +86,653 | 新進 |
| Royal Bank of Canada | 88,687 | $222.8 萬 | 0.00% | −57,520−39.3% | 減碼 |
| Price T Rowe Associates Inc | 95,035 | $238.8 萬 | 0.00% | −2,905−3.0% | 減碼 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 95,755 | $240.5 萬 | 0.00% | +49,642+107.7% | 加碼 |
| State Board of Administration of Florida Retirement System | 96,125 | $241.5 萬 | 0.00% | +530+0.6% | 加碼 |
| Mackenzie Financial Corp | 96,211 | $242.4 萬 | 0.00% | +19,500+25.4% | 加碼 |
| Edgestream Partners, L.P. | 97,443 | $244.8 萬 | 0.07% | −32,308−24.9% | 減碼 |
| Alps Advisors Inc | 103,696 | $260.5 萬 | 0.02% | +40,881+65.1% | 加碼 |
| Wells Fargo & Company | 103,815 | $260.8 萬 | 0.00% | +101,352+4,115.0% | 加碼 |
| New York State Common Retirement Fund | 104,018 | $261.3 萬 | 0.00% | +55,181+113.0% | 加碼 |
| Algert Global LLC | 109,733 | $275.6 萬 | 0.04% | 00.0% | 不變 |
| Two Sigma Advisers, LP | 110,900 | $278.6 萬 | 0.01% | +110,900 | 新進 |
| Rhumbline Advisers | 116,917 | $293.7 萬 | 0.00% | −512−0.4% | 減碼 |
| Exome Asset Management LLC | 135,849 | $341.3 萬 | 1.69% | +135,849 | 新進 |
| ING Groep NV | 139,000 | $349.2 萬 | 0.02% | −1,035,500−88.2% | 減碼 |
| DekaBank Deutsche Girozentrale | 55,000 | $349.7 萬 | 0.01% | 00.0% | 不變 |
| Bridgewater Associates, LP | 143,805 | $361.2 萬 | 0.01% | +143,805 | 新進 |