Xeris Biopharma Holdings, Inc.
XERS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001867096
In the last 90 days, Xeris Biopharma Holdings, Inc. insiders filed 0 open-market purchases and 8 sales; 242 institutions reported holding it in 13F filings for Q2 2026, worth $857.1M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Xeris Biopharma Holdings, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 239
- +17 vs. Q4 2025
- Shares held
- 105.2M
- +16.3M (+18.4%) vs. Q4 2025
- Total value
- $610.3M
- −$87.5M (−12.5%) vs. Q4 2025
- New holders
- 47
- 100 more added
- Sold out
- 30
- 57 more reduced
5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XERS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 242 | $857.1M |
| Q1 2026 | 239 | $610.3M |
| Q4 2025 | 227 | $792.0M |
| Q3 2025 | 231 | $789.3M |
| Q2 2025 | 201 | $422.9M |
| Q1 2025 | 199 | $480.9M |
| Q4 2024 | 162 | $222.2M |
| Q3 2024 | 144 | $182.2M |
| Q2 2024 | 135 | $136.6M |
| Q1 2024 | 142 | $133.7M |
| Q4 2023 | 120 | $140.8M |
| Q3 2023 | 111 | $102.3M |
| Q2 2023 | 105 | $146.7M |
| Q1 2023 | 92 | $80.6M |
| Q4 2022 | 97 | $71.6M |
| Q3 2022 | 101 | $89.3M |
| Q2 2022 | 103 | $91.3M |
| Q1 2022 | 103 | $129.2M |
| Q4 2021 | 92 | $120.2M |
| Q3 2021 | 71 | $42.9M |
| Q2 2021 | 94 | $114.9M |
| Q1 2021 | 103 | $149.7M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Xeris Biopharma Holdings, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Voya Investment Management LLC | 625,310 | $3.63M | 0.00% | +166,981+36.4% | Added |
| UBS Asset Management Americas Inc | 668,074 | $3.87M | 0.00% | +16,629+2.6% | Added |
| Citadel Advisors LLC | 681,634 | $3.95M | 0.00% | +271,814+66.3% | Added |
| Jane Street Group, LLC | 725,616 | $4.21M | 0.00% | +547,794+308.1% | Added |
| Essex Investment Management Co LLC | 747,769 | $4.34M | 0.69% | +13,237+1.8% | Added |
| Trexquant Investment LP | 833,217 | $4.83M | 0.03% | +619,636+290.1% | Added |
| Federated Hermes, Inc. | 856,813 | $4.97M | 0.01% | +1,925+0.2% | Added |
| Bank of America Corp | 874,397 | $5.07M | 0.00% | +156,483+21.8% | Added |
| Driehaus Capital Management LLC | 902,740 | $5.24M | 0.04% | −2,077,827−69.7% | Reduced |
| Granahan Investment Management Inc | 921,854 | $5.35M | 0.26% | −301,550−24.6% | Reduced |
| Ishara Investments LP | 1,025,000 | $5.95M | 6.00% | +225,000+28.1% | Added |
| Knott David M Jr | 1,060,000 | $6.15M | 3.66% | +90,000+9.3% | Added |
| Vanguard Fiduciary Trust Co | 1,133,902 | $6.58M | 0.00% | +1,133,902 | New |
| Algert Global LLC | 1,156,958 | $6.71M | 0.10% | +438,114+60.9% | Added |
| Kennedy Capital Management, Inc. | 1,240,692 | $7.20M | 0.15% | +26,723+2.2% | Added |
| CenterBook Partners LP | 1,248,621 | $7.24M | 0.39% | −142,969−10.3% | Reduced |
| Charles Schwab Investment Management Inc | 1,359,657 | $7.89M | 0.00% | −44,167−3.1% | Reduced |
| Voss Capital, LLC | 1,386,927 | $8.04M | 0.46% | +1,015,218+273.1% | Added |
| AQR Capital Management LLC | 1,394,376 | $8.09M | 0.00% | +436,797+45.6% | Added |
| Northern Trust Corp | 1,444,617 | $8.38M | 0.00% | +57,788+4.2% | Added |
| Goldman Sachs Group Inc | 1,613,650 | $9.36M | 0.00% | +45,229+2.9% | Added |
| UBS Group AG | 1,646,378 | $9.55M | 0.00% | +1,044,544+173.6% | Added |
| Parkman Healthcare Partners LLC | 1,721,264 | $9.98M | 1.04% | +29,679+1.8% | Added |
| Legal & General Group Plc | 1,908,289 | $11.1M | 0.00% | +512,024+36.7% | Added |
| Armistice Capital, LLC | 1,909,838 | $11.1M | 0.37% | +1,909,838 | New |
| Two Sigma Investments, LP | 1,924,202 | $11.2M | 0.01% | +191,535+11.1% | Added |
| Wellington Management Group LLP | 2,171,354 | $12.6M | 0.00% | −115,244−5.0% | Reduced |
| Millennium Management LLC | 2,265,974 | $13.1M | 0.01% | +1,406,923+163.8% | Added |
| Morgan Stanley | 2,572,654 | $14.9M | 0.00% | −135,129−5.0% | Reduced |
| Vanguard Portfolio Management LLC | 2,665,608 | $15.5M | 0.00% | +2,665,608 | New |
| Nuveen, LLC | 2,916,598 | $16.9M | 0.00% | +109,792+3.9% | Added |
| Rosalind Advisors, Inc. | 3,231,700 | $18.7M | 7.68% | +1,120,000+53.0% | Added |
| Qube Research & Technologies Ltd | 4,114,425 | $23.9M | 0.03% | +616,228+17.6% | Added |
| Geode Capital Management, LLC | 4,290,629 | $24.9M | 0.00% | +14,640+0.3% | Added |
| State Street Corp | 4,658,174 | $27.0M | 0.00% | +541,250+13.1% | Added |
| Vanguard Capital Management LLC | 6,980,882 | $40.5M | 0.00% | +6,980,882 | New |
| D. E. Shaw & Co., Inc. | 7,788,811 | $45.2M | 0.04% | +213,961+2.8% | Added |
| BlackRock, Inc. | 12,945,785 | $75.1M | 0.00% | +306,467+2.4% | Added |
| Swiss Life Asset Management Ltd | 33,232 | – | – | +7,173+27.5% | Added |
| Acadian Asset Management LLC | 0 | $0 | 0.00% | −971,598−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −849,334−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −608,080−100.0% | Sold out |
| Castleark Management LLC | 0 | $0 | 0.00% | −445,950−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −341,068−100.0% | Sold out |
| Harvest Investment Services, LLC | 0 | $0 | 0.00% | −292,677−100.0% | Sold out |
| Caxton Associates LLP | 0 | $0 | 0.00% | −174,102−100.0% | Sold out |
| Polen Capital Management LLC | 0 | $0 | 0.00% | −133,416−100.0% | Sold out |
| Ambassador Advisors, LLC | 0 | $0 | 0.00% | −106,730−100.0% | Sold out |
| Resolute Capital Asset Partners LLC | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |
| Calamos Advisors LLC | 0 | $0 | 0.00% | −99,117−100.0% | Sold out |
| EAM Investors, LLC | 0 | $0 | 0.00% | −80,154−100.0% | Sold out |
| Deerfield Management Company, L.P. (Series C) | 0 | $0 | 0.00% | −52,230−100.0% | Sold out |
| Axq Capital, LP | 0 | $0 | 0.00% | −46,454−100.0% | Sold out |
| LJI Wealth Management, LLC | 0 | $0 | 0.00% | −42,350−100.0% | Sold out |
| Ausbil Investment Management Ltd | 0 | $0 | 0.00% | −37,000−100.0% | Sold out |
| VARCOV Co. | 0 | $0 | 0.00% | −31,005−100.0% | Sold out |
| 9823 Capital, L.P. | 0 | $0 | 0.00% | −24,917−100.0% | Sold out |
| Modern Wealth Management, LLC | 0 | $0 | 0.00% | −17,712−100.0% | Sold out |
| Dynamic Technology Lab Private Ltd | 0 | $0 | 0.00% | −17,200−100.0% | Sold out |
| Numerai GP LLC | 0 | $0 | 0.00% | −17,148−100.0% | Sold out |
| Bailard, Inc. | 0 | $0 | 0.00% | −15,300−100.0% | Sold out |
| O'Shaughnessy Asset Management, LLC | 0 | $0 | 0.00% | −11,423−100.0% | Sold out |
| Jain Global LLC | 0 | $0 | 0.00% | −11,114−100.0% | Sold out |
| Amalgamated Bank | 0 | $0 | 0.00% | −4,824−100.0% | Sold out |
| Kestra Advisory Services, LLC | 0 | $0 | 0.00% | −3,192−100.0% | Sold out |
| Quest Partners LLC | 0 | $0 | 0.00% | −1,204−100.0% | Sold out |
| Hillsdale Investment Management Inc. | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| Daiwa Securities Group Inc. | 0 | $0 | 0.00% | −404−100.0% | Sold out |
| Clearstead Advisors, LLC | 0 | $0 | 0.00% | −2−100.0% | Sold out |
| Vanguard Group Inc | – | – | – | – | Not filed |
| Norges Bank | – | – | – | – | Not filed |
| CIBC World Markets Corp | – | – | – | – | Not filed |
| CIBC Private Wealth Group, LLC | – | – | – | – | Not filed |
| Global Retirement Partners, LLC | – | – | – | – | Not filed |