Wave Life Sciences, Inc.
WVE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001631574
In the last 90 days, Wave Life Sciences, Inc. insiders filed 0 open-market purchases and 4 sales; 239 institutions reported holding it in 13F filings for Q2 2026, worth $1.06B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.
13F holders, Q1 2026
Institutional positions in Wave Life Sciences, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 232
- +16 vs. Q4 2025
- Shares held
- 172.6M
- −6.53M (−3.6%) vs. Q4 2025
- Total value
- $1.25B
- −$1.80B (−59.0%) vs. Q4 2025
- New holders
- 51
- 107 more added
- Sold out
- 35
- 48 more reduced
3 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting WVE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 239 | $1.06B |
| Q1 2026 | 232 | $1.25B |
| Q4 2025 | 219 | $3.11B |
| Q3 2025 | 189 | $1.05B |
| Q2 2025 | 177 | $903.1M |
| Q1 2025 | 197 | $1.06B |
| Q4 2024 | 184 | $1.59B |
| Q3 2024 | 162 | $986.1M |
| Q2 2024 | 144 | $474.4M |
| Q1 2024 | 132 | $572.3M |
| Q4 2023 | 115 | $468.0M |
| Q3 2023 | 85 | $417.4M |
| Q2 2023 | 81 | $262.7M |
| Q1 2023 | 73 | $303.5M |
| Q4 2022 | 75 | $476.9M |
| Q3 2022 | 61 | $242.8M |
| Q2 2022 | 60 | $220.3M |
| Q1 2022 | 82 | $95.4M |
| Q4 2021 | 90 | $148.5M |
| Q3 2021 | 88 | $183.5M |
| Q2 2021 | 87 | $246.7M |
| Q1 2021 | 102 | $214.8M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Wave Life Sciences, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Intech Investment Management LLC | 39,437 | $285.9K | 0.00% | +8,770+28.6% | Added |
| Raymond James Financial Inc | 39,625 | $287.3K | 0.00% | −71,545−64.4% | Reduced |
| Knott David M Jr | 40,000 | $290.0K | 0.17% | −50,000−55.6% | Reduced |
| Ameriprise Financial Inc | 40,374 | $292.7K | 0.00% | −358,042−89.9% | Reduced |
| Caption Management, LLC | 43,200 | $313.2K | 0.01% | +43,200 | New |
| Glenmede Trust Co NA | 44,241 | $320.7K | 0.00% | +1,509+3.5% | Added |
| ADAR1 Capital Management, LLC | 44,900 | $325.5K | 0.02% | +44,900 | New |
| Matisse Capital | 46,723 | $338.7K | 0.14% | +4,530+10.7% | Added |
| Quantinno Capital Management LP | 47,885 | $347.2K | 0.00% | +8,960+23.0% | Added |
| Janus Henderson Group PLC | 51,700 | $374.6K | 0.00% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 51,955 | $376.7K | 0.00% | −10,774−17.2% | Reduced |
| Verition Fund Management LLC | 53,895 | $390.7K | 0.00% | +53,895 | New |
| J. Goldman & Co LP | 53,896 | $390.7K | 0.02% | +134+0.2% | Added |
| Vanguard Global Advisers, LLC | 56,601 | $410.4K | 0.00% | +56,601 | New |
| Russell Investments Group, Ltd. | 58,052 | $420.9K | 0.00% | +8,149+16.3% | Added |
| Man Group plc | 64,036 | $464.3K | 0.00% | +32,618+103.8% | Added |
| Winton Group Ltd | 65,045 | $471.6K | 0.02% | +50,345+342.5% | Added |
| Handelsbanken Fonder AB | 65,500 | $475.0K | 0.00% | +10,800+19.7% | Added |
| Voya Investment Management LLC | 69,092 | $500.9K | 0.00% | −43,783−38.8% | Reduced |
| D. E. Shaw & Co., Inc. | 72,305 | $524.2K | 0.00% | −193,827−72.8% | Reduced |
| Vanguard Asset Management, Ltd | 74,695 | $541.5K | 0.00% | +74,695 | New |
| MetLife Investment Management | 76,265 | $552.9K | 0.00% | +11,502+17.8% | Added |
| Virtu Financial LLC | 76,779 | $557.0K | 0.02% | +49,890+185.5% | Added |
| a16z Perennial Management, L.P. | 77,619 | $562.7K | 0.05% | 00.0% | Unchanged |
| Legal & General Group Plc | 79,054 | $572.7K | 0.00% | −14,931−15.9% | Reduced |
| SEI Investments Co | 80,161 | $581.2K | 0.00% | +25,704+47.2% | Added |
| Engineers Gate Manager LP | 80,217 | $581.6K | 0.01% | +80,217 | New |
| Nomura Asset Management International Inc. | 81,955 | $594.0K | 0.00% | −121,789−59.8% | Reduced |
| Ikarian Capital, LLC | 85,285 | $618.3K | 0.09% | 00.0% | Unchanged |
| Quadrature Capital Ltd | 86,677 | $628.4K | 0.01% | +86,677 | New |
| Simplex Trading, LLC | 89,263 | $647.2K | 0.02% | +68,137+322.5% | Added |
| Tudor Investment Corp Et Al | 97,900 | $709.8K | 0.00% | +97,900 | New |
| State of Wisconsin Investment Board | 108,164 | $784.2K | 0.00% | +21,023+24.1% | Added |
| XTX Topco Ltd | 109,862 | $796.5K | 0.01% | +109,862 | New |
| Deutsche Bank AG | 114,110 | $827.3K | 0.00% | +18,404+19.2% | Added |
| James J. Burns & Company, LLC | 114,800 | $832.3K | 0.11% | +8,998+8.5% | Added |
| Wells Fargo & Company | 136,173 | $987.3K | 0.00% | −64,717−32.2% | Reduced |
| Fred Alger Management, LLC | 139,218 | $1.01M | 0.00% | +139,218 | New |
| Capstone Capital Management Ltd | 144,029 | $1.04M | 1.05% | +144,029 | New |
| Advisory Services Network, LLC | 144,950 | $1.05M | 0.01% | +124,050+593.5% | Added |
| California State Teachers Retirement System | 145,206 | $1.05M | 0.00% | +37,526+34.8% | Added |
| Twinbeech Capital LP | 145,825 | $1.06M | 0.11% | +145,825 | New |
| Burkehill Global Management, LP | 150,000 | $1.09M | 0.05% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 150,368 | $1.09M | 0.00% | +15,810+11.7% | Added |
| Qube Research & Technologies Ltd | 155,924 | $1.13M | 0.00% | +155,924 | New |
| Y-Intercept (Hong Kong) Ltd | 157,013 | $1.14M | 0.02% | +157,013 | New |
| Boothbay Fund Management, LLC | 160,311 | $1.16M | 0.03% | −74,488−31.7% | Reduced |
| F/M Investments LLC | 164,921 | $1.20M | 0.08% | −230,973−58.3% | Reduced |
| Rhumbline Advisers | 167,528 | $1.21M | 0.00% | +25,633+18.1% | Added |
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 173,000 | $1.25M | 0.04% | 00.0% | Unchanged |
| Elmind Capital, LP | 177,846 | $1.29M | 0.37% | −270,000−60.3% | Reduced |
| Caitong International Asset Management Co., Ltd | 180,980 | $1.31M | 0.24% | +170,623+1,647.4% | Added |
| Capital Fund Management S.A. | 183,331 | $1.33M | 0.01% | +183,331 | New |
| Sofinnova Investments, Inc. | 189,253 | $1.37M | 0.07% | +31,071+19.6% | Added |
| Barclays PLC | 189,865 | $1.38M | 0.00% | −86,916−31.4% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 195,840 | $1.42M | 0.02% | −34,672−15.0% | Reduced |
| Invesco Ltd. | 199,740 | $1.45M | 0.00% | +19,808+11.0% | Added |
| Scientech Research LLC | 200,331 | $1.45M | 1.21% | +184,758+1,186.4% | Added |
| Balyasny Asset Management LLC | 211,074 | $1.53M | 0.00% | +211,074 | New |
| Swiss National Bank | 219,700 | $1.59M | 0.00% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 225,114 | $1.63M | 0.00% | +60,129+36.4% | Added |
| Bank of America Corp | 236,760 | $1.72M | 0.00% | +53,905+29.5% | Added |
| Manufacturers Life Insurance Company, The | 240,983 | $1.75M | 0.00% | +58,255+31.9% | Added |
| Privium Fund Management B.V. | 241,010 | $1.75M | 0.36% | +48,000+24.9% | Added |
| Susquehanna International Group, LLP | 259,825 | $1.88M | 0.00% | −119,162−31.4% | Reduced |
| Moody Aldrich Partners LLC | 272,533 | $1.98M | 0.36% | −1,892−0.7% | Reduced |
| Platinum Investment Management Ltd | 275,269 | $2.00M | 0.50% | +44,582+19.3% | Added |
| BNP Paribas Arbitrage, SA | 281,023 | $2.04M | 0.00% | +199,001+242.6% | Added |
| Gsa Capital Partners LLP | 282,719 | $2.05M | 0.13% | +282,719 | New |
| Voloridge Investment Management, LLC | 288,502 | $2.09M | 0.01% | −433,735−60.1% | Reduced |
| Alliancebernstein L.P. | 125,096 | $2.13M | 0.00% | +13,066+11.7% | Added |
| Newtyn Management, LLC | 300,000 | $2.17M | 0.23% | 00.0% | Unchanged |
| HRT Financial LP | 321,376 | $2.33M | 0.01% | +21,658+7.2% | Added |
| Aquatic Capital Management LLC | 323,573 | $2.35M | 0.07% | +323,573 | New |
| TD Asset Management Inc | 338,826 | $2.46M | 0.00% | +86,666+34.4% | Added |
| Woodline Partners LP | 350,531 | $2.54M | 0.01% | 00.0% | Unchanged |
| Jump Financial, LLC | 360,054 | $2.61M | 0.04% | +46,545+14.8% | Added |
| Bank of New York Mellon Corp | 361,204 | $2.62M | 0.00% | +39,759+12.4% | Added |
| Wellington Management Group LLP | 373,794 | $2.71M | 0.00% | +8,559+2.3% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 415,458 | $3.01M | 0.01% | +3,964+1.0% | Added |
| AQR Capital Management LLC | 451,185 | $3.27M | 0.00% | +248,464+122.6% | Added |
| Walleye Capital LLC | 493,512 | $3.58M | 0.02% | +114,689+30.3% | Added |
| Citigroup Inc | 501,477 | $3.64M | 0.00% | +454,718+972.5% | Added |
| Kennedy Capital Management, Inc. | 519,768 | $3.77M | 0.08% | +27,331+5.6% | Added |
| UBS Group AG | 538,997 | $3.91M | 0.00% | +270,274+100.6% | Added |
| Sphera Funds Management Ltd. | 548,272 | $3.97M | 0.68% | +140,106+34.3% | Added |
| Standard Life Aberdeen plc | 550,000 | $3.99M | 0.01% | +550,000 | New |
| Renaissance Technologies LLC | 597,220 | $4.33M | 0.01% | +360,800+152.6% | Added |
| Tang Capital Management LLC | 600,000 | $4.35M | 0.22% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 670,170 | $4.44M | 0.00% | −222,716−24.9% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 624,735 | $4.53M | 0.01% | +555,657+804.4% | Added |
| Nuveen, LLC | 657,720 | $4.77M | 0.00% | +324,985+97.7% | Added |
| SymBiosis Capital Partners, LLC | 750,000 | $5.44M | 10.30% | +750,000 | New |
| Emerald Mutual Fund Advisers Trust | 814,529 | $5.91M | 0.29% | −600,136−42.4% | Reduced |
| Baker Bros. Advisors LP | 822,638 | $5.96M | 0.03% | +478,575+139.1% | Added |
| Vanguard Fiduciary Trust Co | 878,833 | $6.37M | 0.00% | +878,833 | New |
| Kynam Capital Management, LP | 965,193 | $7.00M | 0.44% | −1,203,912−55.5% | Reduced |
| Millennium Management LLC | 972,241 | $7.05M | 0.01% | +387,608+66.3% | Added |
| Adage Capital Partners GP, L.L.C. | 1,000,000 | $7.25M | 0.01% | −8,786,061−89.8% | Reduced |
| Trexquant Investment LP | 1,089,642 | $7.90M | 0.06% | +698,531+178.6% | Added |