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Tango Therapeutics, Inc.

TNGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001819133

In the last 90 days, Tango Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $6.60B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Tango Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
170
+31 vs. Q3 2025
Shares held
172.4M
+32.7M (+23.4%) vs. Q3 2025
Total value
$1.53B
+$353.7M (+30.1%) vs. Q3 2025
New holders
53
75 more added
Sold out
22
27 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TNGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 170 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 46 institutionsQ4 2021: 58 institutionsQ1 2022: 72 institutionsQ2 2022: 77 institutionsQ3 2022: 87 institutionsQ4 2022: 82 institutionsQ1 2023: 92 institutionsQ2 2023: 89 institutionsQ3 2023: 100 institutionsQ4 2023: 121 institutionsQ1 2024: 126 institutionsQ2 2024: 120 institutionsQ3 2024: 121 institutionsQ4 2024: 138 institutionsQ1 2025: 122 institutionsQ2 2025: 115 institutionsQ3 2025: 141 institutionsQ4 2025: 170 institutionsQ1 2026: 194 institutionsQ2 2026: 247 institutions
Value heldQ4 2025: $1.53B
Q1 2021: $0Q2 2021: $0Q3 2021: $844.9MQ4 2021: $741.0MQ1 2022: $528.2MQ2 2022: $319.1MQ3 2022: $246.8MQ4 2022: $498.4MQ1 2023: $275.9MQ2 2023: $226.8MQ3 2023: $999.9MQ4 2023: $927.1MQ1 2024: $781.2MQ2 2024: $846.0MQ3 2024: $781.2MQ4 2024: $329.2MQ1 2025: $147.0MQ2 2025: $651.7MQ3 2025: $1.18BQ4 2025: $1.53BQ1 2026: $3.78BQ2 2026: $6.60B
Institutions holding TNGX and their total value by quarter
QuarterHoldersValue
Q2 2026247$6.60B
Q1 2026194$3.78B
Q4 2025170$1.53B
Q3 2025141$1.18B
Q2 2025115$651.7M
Q1 2025122$147.0M
Q4 2024138$329.2M
Q3 2024121$781.2M
Q2 2024120$846.0M
Q1 2024126$781.2M
Q4 2023121$927.1M
Q3 2023100$999.9M
Q2 202389$226.8M
Q1 202392$275.9M
Q4 202282$498.4M
Q3 202287$246.8M
Q2 202277$319.1M
Q1 202272$528.2M
Q4 202158$741.0M
Q3 202146$844.9M
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Tango Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding TNGX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
ExodusPoint Capital Management, LP32,897$291.5K0.00%−48,341−59.5%Reduced
Manufacturers Life Insurance Company, The32,342$286.6K0.00%+9,648+42.5%Added
Engineers Gate Manager LP30,599$271.1K0.00%+30,599New
VARCOV Co.29,486$261.2K0.10%+29,486New
State of Wisconsin Investment Board29,337$259.9K0.00%+29,337New
Virtus Investment Advisers, Inc.28,452$252.1K0.07%+5,920+26.3%Added
Police & Firemen's Retirement System of New Jersey28,294$250.7K0.00%+7,746+37.7%Added
Massachusetts Financial Services Co28,023$248.3K0.00%+28,023New
EverSource Wealth Advisors, LLC25,646$227.2K0.01%−1,007−3.8%Reduced
ProShare Advisors LLC25,384$224.9K0.00%+9,154+56.4%Added
Cantor Fitzgerald, L. P.25,000$221.5K0.01%+25,000New
New York State Common Retirement Fund24,576$217.7K0.00%+9,000+57.8%Added
Quantinno Capital Management LP22,339$197.9K0.00%+10,064+82.0%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.21,872$195.3K0.00%+21,872New
SG Americas Securities, LLC22,006$195.0K0.00%+22,006New
China Universal Asset Management Co., Ltd.21,946$194.4K0.01%+2,444+12.5%Added
Bridgeway Capital Management, LLC21,500$190.5K0.00%00.0%Unchanged
JustInvest LLC20,402$180.8K0.00%+189+0.9%Added
Axq Capital, LP20,268$179.6K0.04%+6,800+50.5%Added
Tower Research Capital LLC (TRC)19,741$174.9K0.00%+13,297+206.3%Added
Bridgefront Capital, LLC19,479$172.6K0.04%+19,479New
Bank of Montreal16,494$146.1K0.00%+16,494New
Atria Investments LLC14,822$131.3K0.00%+14,822New
Entropy Technologies, LP14,792$131.1K0.01%+14,792New
State Board of Administration of Florida Retirement System12,780$113.2K0.00%00.0%Unchanged
Arizona State Retirement System12,273$108.7K0.00%+12,273New
LPL Financial LLC12,000$106.3K0.00%+12,000New
Pinnacle Wealth Planning Services, Inc.10,782$95.5K0.01%+10,782New
CI Private Wealth, LLC10,529$93.3K0.00%−971−8.4%Reduced
Mercer Global Advisors Inc10,461$92.7K0.00%−865−7.6%Reduced
Victory Capital Management Inc10,206$90.4K0.00%+10,206New
Soleus Capital Management, L.P.10,000$88.6K0.00%−290,000−96.7%Reduced
Russell Investments Group, Ltd.9,794$86.8K0.00%+2,065+26.7%Added
KLP Kapitalforvaltning AS9,700$85.9K0.00%+9,700New
BNP Paribas Arbitrage, SA9,563$84.7K0.00%−5,527−36.6%Reduced
Ameritas Investment Partners, Inc.8,633$76.5K0.00%+2,640+44.1%Added
Mirae Asset Global Investments Co., Ltd.6,544$58.0K0.00%+2,243+52.2%Added
Sterling Capital Management LLC6,130$54.3K0.00%+1,180+23.8%Added
CWM, LLC4,832$43.0K0.00%−38−0.8%Reduced
Antipodes Partners Ltd4,513$40.0K0.00%+4,513New
Zurcher Kantonalbank (Zurich Cantonalbank)4,467$39.6K0.00%+4,464+148,800.0%Added
Global Retirement Partners, LLC4,004$35.5K0.00%+4,004New
Royal Bank of Canada3,682$32.0K0.00%−283,817−98.7%Reduced
Amalgamated Bank3,341$30.0K0.00%+1,723+106.5%Added
GF Fund Management Co. Ltd.2,646$23.4K0.00%+252+10.5%Added
Comerica Bank2,158$19.1K0.00%+2,158New
Nisa Investment Advisors, LLC1,740$15.4K0.00%00.0%Unchanged
TFC Financial Management1,300$11.5K0.00%+500+62.5%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,025$9.00K0.00%+1,025New
Rockefeller Capital Management L.P.887$7.86K0.00%+765+627.0%Added
Advisor Group Holdings, Inc.692$6.13K0.00%+101+17.1%Added
Optiver Holding B.V.576$5.10K0.00%−38−6.2%Reduced
GAMMA Investing LLC477$4.23K0.00%+13+2.8%Added
Quest Partners LLC375$3.32K0.00%−711−65.5%Reduced
Federated Hermes, Inc.362$3.21K0.00%00.0%Unchanged
Farther Finance Advisors, LLC355$3.15K0.00%+330+1,320.0%Added
Daiwa Securities Group Inc.355$3.00K0.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd320$2.83K0.00%+320New
Flagship Harbor Advisors, LLC300$2.66K0.00%+300New
IFP Advisors, Inc233$2.06K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.212$1.88K0.00%00.0%Unchanged
WPG Advisers, LLC159$1.41K0.00%+159New
Allworth Financial LP45$3990.00%+7+18.4%Added
Clearstead Advisors, LLC45$3990.00%+45New
Larson Financial Group LLC34$3010.00%+34New
Rothschild Investment LLC26$2300.00%+6+30.0%Added
SBI Securities Co., Ltd.19$1680.00%−35−64.8%Reduced
SRS Capital Advisors, Inc.8$710.00%−1,194−99.3%Reduced
Essential Partners LLC4$350.00%+4New
Covestor Ltd32$00.00%00.0%Unchanged
EcoR1 Capital, LLC0$00.00%−10,630,736−100.0%Sold out
Gilead Sciences, Inc.0$00.00%−4,854,443−100.0%Sold out
Paradigm Biocapital Advisors LP0$00.00%−3,086,184−100.0%Sold out
Ra Capital Management, L.P.0$00.00%−2,000,000−100.0%Sold out
Commodore Capital LP0$00.00%−1,500,000−100.0%Sold out
Avoro Capital Advisors LLC0$00.00%−545,000−100.0%Sold out
StemPoint Capital LP0$00.00%−245,378−100.0%Sold out
Readystate Asset Management LP0$00.00%−245,109−100.0%Sold out
Fred Alger Management, LLC0$00.00%−230,316−100.0%Sold out
Susquehanna Fundamental Investments, LLC0$00.00%−157,233−100.0%Sold out
Blue Owl Capital Holdings LP0$00.00%−119,416−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−94,100−100.0%Sold out
Renaissance Technologies LLC0$00.00%−55,300−100.0%Sold out
Quadrature Capital Ltd0$00.00%−36,189−100.0%Sold out
Harvest Investment Services, LLC0$00.00%−31,840−100.0%Sold out
Clear Harbor Asset Management, LLC0$00.00%−30,300−100.0%Sold out
J. Goldman & Co LP0$00.00%−29,036−100.0%Sold out
Simplicity Wealth,LLC0$00.00%−26,961−100.0%Sold out
TD Asset Management Inc0$00.00%−18,072−100.0%Sold out
DRW Securities, LLC0$00.00%−14,778−100.0%Sold out
Belvedere Trading LLC0$00.00%−10,845−100.0%Sold out
US Bancorp0$00.00%−53−100.0%Sold out
Cubist Systematic Strategies, LLC––––Not filed
Corton Capital Inc.––––Not filed