Tango Therapeutics, Inc.
TNGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001819133
In the last 90 days, Tango Therapeutics, Inc. insiders filed 0 open-market purchases and 4 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $6.60B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Tango Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 170
- +31 vs. Q3 2025
- Shares held
- 172.4M
- +32.7M (+23.4%) vs. Q3 2025
- Total value
- $1.53B
- +$353.7M (+30.1%) vs. Q3 2025
- New holders
- 53
- 75 more added
- Sold out
- 22
- 27 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TNGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 247 | $6.60B |
| Q1 2026 | 194 | $3.78B |
| Q4 2025 | 170 | $1.53B |
| Q3 2025 | 141 | $1.18B |
| Q2 2025 | 115 | $651.7M |
| Q1 2025 | 122 | $147.0M |
| Q4 2024 | 138 | $329.2M |
| Q3 2024 | 121 | $781.2M |
| Q2 2024 | 120 | $846.0M |
| Q1 2024 | 126 | $781.2M |
| Q4 2023 | 121 | $927.1M |
| Q3 2023 | 100 | $999.9M |
| Q2 2023 | 89 | $226.8M |
| Q1 2023 | 92 | $275.9M |
| Q4 2022 | 82 | $498.4M |
| Q3 2022 | 87 | $246.8M |
| Q2 2022 | 77 | $319.1M |
| Q1 2022 | 72 | $528.2M |
| Q4 2021 | 58 | $741.0M |
| Q3 2021 | 46 | $844.9M |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Tango Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Farallon Capital Management, L.L.C. | 13,061,411 | $115.7M | 0.60% | +2,304,411+21.4% | Added |
| TCG Crossover Management, LLC | 12,762,094 | $113.1M | 3.74% | +4,225,898+49.5% | Added |
| Boxer Capital Management, LLC | 10,876,219 | $96.4M | 21.09% | +1,104,734+11.3% | Added |
| Adage Capital Partners GP, L.L.C. | 10,607,924 | $94.0M | 0.14% | +8,096,924+322.5% | Added |
| Woodline Partners LP | 10,072,225 | $89.2M | 0.35% | +4,042,297+67.0% | Added |
| BlackRock, Inc. | 8,540,797 | $75.7M | 0.00% | +2,893,878+51.2% | Added |
| Siren, L.L.C. | 8,165,374 | $72.3M | 2.16% | +2,282,186+38.8% | Added |
| TRV GP IV, LLC | 7,874,574 | $69.8M | 27.35% | −5,989,401−43.2% | Reduced |
| Nextech Invest, Ltd. | 7,266,081 | $64.4M | 6.22% | +1,732,101+31.3% | Added |
| Vanguard Group Inc | 6,750,977 | $59.8M | 0.00% | +1,698,974+33.6% | Added |
| State Street Corp | 6,218,567 | $55.1M | 0.00% | +2,853,362+84.8% | Added |
| Balyasny Asset Management LLC | 5,278,580 | $46.8M | 0.09% | +1,806,373+52.0% | Added |
| Goldman Sachs Group Inc | 4,942,414 | $43.8M | 0.01% | +3,432,939+227.4% | Added |
| Logos Global Management LP | 4,200,000 | $37.2M | 2.48% | +3,250,000+342.1% | Added |
| Bellevue Group AG | 3,927,670 | $34.8M | 0.66% | +3,927,670 | New |
| Caligan Partners LP | 3,729,895 | $33.0M | 3.03% | +3,729,895 | New |
| Nantahala Capital Management, LLC | 3,572,633 | $31.7M | 1.89% | +1,762,685+97.4% | Added |
| Deerfield Management Company, L.P. (Series C) | 2,906,946 | $25.8M | 0.33% | +2,906,946 | New |
| FMR LLC | 2,867,548 | $25.4M | 0.00% | +2,861,122+44,524.2% | Added |
| Suvretta Capital Management, LLC | 2,662,227 | $23.6M | 0.59% | +2,662,227 | New |
| Janus Henderson Group PLC | 2,644,237 | $23.5M | 0.01% | +341,963+14.9% | Added |
| Geode Capital Management, LLC | 2,553,656 | $22.6M | 0.00% | +670,879+35.6% | Added |
| Deep Track Capital, LP | 2,454,562 | $21.7M | 0.50% | +1,000,000+68.7% | Added |
| Vivo Capital, LLC | 2,154,780 | $19.1M | 1.23% | +1,378,081+177.4% | Added |
| Point72 Asset Management, L.P. | 1,974,035 | $17.5M | 0.03% | −945,415−32.4% | Reduced |
| RTW Investments, LP | 1,491,228 | $13.2M | 0.13% | +1,491,228 | New |
| Morgan Stanley | 1,421,794 | $12.6M | 0.00% | +1,170,001+464.7% | Added |
| Franklin Resources Inc | 1,398,057 | $12.4M | 0.00% | +471,153+50.8% | Added |
| D. E. Shaw & Co., Inc. | 1,025,553 | $9.09M | 0.01% | +595,174+138.3% | Added |
| Affinity Asset Advisors, LLC | 1,000,000 | $8.86M | 0.64% | +1,000,000 | New |
| UBS Group AG | 990,458 | $8.78M | 0.00% | +829,980+517.2% | Added |
| Boothbay Fund Management, LLC | 957,282 | $8.48M | 0.22% | +957,282 | New |
| Charles Schwab Investment Management Inc | 840,992 | $7.45M | 0.00% | +182,700+27.8% | Added |
| Northern Trust Corp | 803,199 | $7.12M | 0.00% | +197,638+32.6% | Added |
| Candriam Luxembourg S.C.A. | 708,812 | $6.28M | 0.03% | 00.0% | Unchanged |
| ArrowMark Colorado Holdings LLC | 708,385 | $6.28M | 0.14% | 00.0% | Unchanged |
| Bessemer Group Inc | 708,398 | $6.28M | 0.01% | 00.0% | Unchanged |
| Bain Capital Life Sciences Investors, LLC | 653,493 | $5.79M | 0.44% | −2,058,515−75.9% | Reduced |
| Millennium Management LLC | 593,004 | $5.25M | 0.00% | −702,397−54.2% | Reduced |
| Sphera Funds Management Ltd. | 544,563 | $4.82M | 1.01% | +544,563 | New |
| Perceptive Advisors LLC | 513,035 | $4.55M | 0.08% | +513,035 | New |
| Dimensional Fund Advisors LP | 487,076 | $4.32M | 0.00% | −185,659−27.6% | Reduced |
| Bank of America Corp | 478,062 | $4.24M | 0.00% | +322,615+207.5% | Added |
| T. Rowe Price Investment Management, Inc. | 446,213 | $3.95M | 0.00% | −3,080,146−87.3% | Reduced |
| Rock Springs Capital Management LP | 386,915 | $3.43M | 0.18% | +386,915 | New |
| Barclays PLC | 368,187 | $3.26M | 0.00% | +2,507+0.7% | Added |
| Mass General Brigham, Inc | 354,192 | $3.14M | 0.39% | +354,192 | New |
| Bank of New York Mellon Corp | 343,840 | $3.05M | 0.00% | +151,492+78.8% | Added |
| Marshall Wace, LLP | 329,231 | $2.92M | 0.00% | −1,160,287−77.9% | Reduced |
| Qube Research & Technologies Ltd | 318,676 | $2.82M | 0.00% | +318,676 | New |
| Nuveen, LLC | 300,441 | $2.66M | 0.00% | −627,571−67.6% | Reduced |
| Great Lakes Advisors, LLC | 294,303 | $2.61M | 0.02% | −129,548−30.6% | Reduced |
| Acuta Capital Partners, LLC | 282,732 | $2.51M | 1.70% | +282,732 | New |
| Voloridge Investment Management, LLC | 255,127 | $2.26M | 0.01% | −129,080−33.6% | Reduced |
| Congress Asset Management Co | 234,628 | $2.08M | 0.01% | +6,508+2.9% | Added |
| Wellington Management Group LLP | 233,857 | $2.07M | 0.00% | −19,431−7.7% | Reduced |
| Rafferty Asset Management, LLC | 226,601 | $2.01M | 0.01% | +81,285+55.9% | Added |
| Seven Fleet Capital Management LP | 215,172 | $1.91M | 1.29% | +215,172 | New |
| Integral Health Asset Management, LLC | 200,000 | $1.77M | 0.09% | +200,000 | New |
| TRV GP VI, LLC | 194,174 | $1.72M | 1.16% | 00.0% | Unchanged |
| Fisher Asset Management, LLC | 187,693 | $1.66M | 0.00% | −22,659−10.8% | Reduced |
| Invesco Ltd. | 177,610 | $1.57M | 0.00% | −854,307−82.8% | Reduced |
| Squarepoint Ops LLC | 173,936 | $1.54M | 0.00% | +173,936 | New |
| Citadel Advisors LLC | 151,880 | $1.35M | 0.00% | +151,880 | New |
| Two Sigma Investments, LP | 144,432 | $1.28M | 0.00% | 00.0% | Unchanged |
| ADAR1 Capital Management, LLC | 140,021 | $1.24M | 0.09% | +140,021 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 129,476 | $1.15M | 0.00% | +129,476 | New |
| Rhumbline Advisers | 129,107 | $1.14M | 0.00% | +21,268+19.7% | Added |
| Verition Fund Management LLC | 121,781 | $1.08M | 0.01% | +97,029+392.0% | Added |
| Wells Fargo & Company | 121,186 | $1.07M | 0.00% | +66,181+120.3% | Added |
| Gsa Capital Partners LLP | 118,593 | $1.05M | 0.09% | +118,593 | New |
| Alliancebernstein L.P. | 106,490 | $943.5K | 0.00% | +4,220+4.1% | Added |
| Trexquant Investment LP | 105,268 | $932.7K | 0.01% | −93,813−47.1% | Reduced |
| Swiss National Bank | 87,800 | $777.9K | 0.00% | +87,800 | New |
| Profund Advisors LLC | 83,759 | $742.1K | 0.02% | +52,471+167.7% | Added |
| AQR Capital Management LLC | 82,233 | $728.6K | 0.00% | +3,058+3.9% | Added |
| Deutsche Bank AG | 74,203 | $657.4K | 0.00% | +15,054+25.5% | Added |
| Tudor Investment Corp Et Al | 68,251 | $604.7K | 0.00% | +14,679+27.4% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 62,634 | $551.9K | 0.00% | +22,236+55.0% | Added |
| MetLife Investment Management | 59,692 | $528.9K | 0.00% | +11,966+25.1% | Added |
| Y-Intercept (Hong Kong) Ltd | 59,330 | $525.7K | 0.01% | +22,367+60.5% | Added |
| Price T Rowe Associates Inc | 58,434 | $518.0K | 0.00% | +17,765+43.7% | Added |
| Los Angeles Capital Management LLC | 64,243 | $512.0K | 0.00% | +47,058+273.8% | Added |
| JPMorgan Chase & Co | 56,835 | $503.6K | 0.00% | +22,919+67.6% | Added |
| DekaBank Deutsche Girozentrale | 60,000 | $502.0K | 0.00% | 00.0% | Unchanged |
| SEI Investments Co | 53,927 | $477.8K | 0.00% | +43,882+436.9% | Added |
| Graham Capital Management, L.P. | 51,319 | $454.7K | 0.02% | +51,319 | New |
| Canada Pension Plan Investment Board | 50,400 | $446.5K | 0.00% | +50,400 | New |
| California State Teachers Retirement System | 48,210 | $427.1K | 0.00% | +43,422+906.9% | Added |
| Voya Investment Management LLC | 47,811 | $423.6K | 0.00% | +34,346+255.1% | Added |
| SmartHarvest Portfolios, LLC | 46,123 | $408.6K | 0.14% | +46,123 | New |
| Creative Planning | 41,907 | $371.3K | 0.00% | +6,663+18.9% | Added |
| UBS Asset Management Americas Inc | 41,453 | $367.3K | 0.00% | +41,453 | New |
| Legal & General Group Plc | 39,430 | $349.4K | 0.00% | +32,985+511.8% | Added |
| Intech Investment Management LLC | 38,941 | $345.0K | 0.00% | +10,789+38.3% | Added |
| XTX Topco Ltd | 37,838 | $335.2K | 0.01% | +37,838 | New |
| Citigroup Inc | 36,236 | $321.1K | 0.00% | +18,134+100.2% | Added |
| Janney Montgomery Scott LLC | 36,000 | $319.0K | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 35,216 | $312.0K | 0.00% | −53,623−60.4% | Reduced |
| Philadelphia Financial Management of San Francisco, LLC | 33,291 | $295.0K | 0.06% | +33,291 | New |