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Tango Therapeutics, Inc.

TNGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001819133

In the last 90 days, Tango Therapeutics, Inc. insiders filed 0 open-market purchases and 4 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $6.60B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Tango Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
141
+27 vs. Q2 2025
Shares held
140.0M
+12.7M (+10.0%) vs. Q2 2025
Total value
$1.18B
+$524.1M (+80.4%) vs. Q2 2025
New holders
37
48 more added
Sold out
10
35 more reduced

1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TNGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 141 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 46 institutionsQ4 2021: 58 institutionsQ1 2022: 72 institutionsQ2 2022: 77 institutionsQ3 2022: 87 institutionsQ4 2022: 82 institutionsQ1 2023: 92 institutionsQ2 2023: 89 institutionsQ3 2023: 100 institutionsQ4 2023: 121 institutionsQ1 2024: 126 institutionsQ2 2024: 120 institutionsQ3 2024: 121 institutionsQ4 2024: 138 institutionsQ1 2025: 122 institutionsQ2 2025: 115 institutionsQ3 2025: 141 institutionsQ4 2025: 170 institutionsQ1 2026: 194 institutionsQ2 2026: 247 institutions
Value heldQ3 2025: $1.18B
Q1 2021: $0Q2 2021: $0Q3 2021: $844.9MQ4 2021: $741.0MQ1 2022: $528.2MQ2 2022: $319.1MQ3 2022: $246.8MQ4 2022: $498.4MQ1 2023: $275.9MQ2 2023: $226.8MQ3 2023: $999.9MQ4 2023: $927.1MQ1 2024: $781.2MQ2 2024: $846.0MQ3 2024: $781.2MQ4 2024: $329.2MQ1 2025: $147.0MQ2 2025: $651.7MQ3 2025: $1.18BQ4 2025: $1.53BQ1 2026: $3.78BQ2 2026: $6.60B
Institutions holding TNGX and their total value by quarter
QuarterHoldersValue
Q2 2026247$6.60B
Q1 2026194$3.78B
Q4 2025170$1.53B
Q3 2025141$1.18B
Q2 2025115$651.7M
Q1 2025122$147.0M
Q4 2024138$329.2M
Q3 2024121$781.2M
Q2 2024120$846.0M
Q1 2024126$781.2M
Q4 2023121$927.1M
Q3 2023100$999.9M
Q2 202389$226.8M
Q1 202392$275.9M
Q4 202282$498.4M
Q3 202287$246.8M
Q2 202277$319.1M
Q1 202272$528.2M
Q4 202158$741.0M
Q3 202146$844.9M
Q2 20210$0
Q1 20210$0

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Tango Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding TNGX in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
TRV GP IV, LLC13,863,975$116.5M42.51%−2,995,100−17.8%Reduced
Farallon Capital Management, L.L.C.10,757,000$90.4M0.51%+1,600,000+17.5%Added
EcoR1 Capital, LLC10,630,736$89.3M4.29%00.0%Unchanged
Boxer Capital Management, LLC9,771,485$82.1M26.16%00.0%Unchanged
TCG Crossover Management, LLC8,536,196$71.7M3.53%−2,199,804−20.5%Reduced
Woodline Partners LP6,029,928$50.7M0.24%+220.0%Added
Siren, L.L.C.5,883,188$49.4M1.93%+2,518,374+74.8%Added
BlackRock, Inc.5,646,919$47.4M0.00%+183,653+3.4%Added
Nextech Invest, Ltd.5,533,980$46.5M7.08%00.0%Unchanged
Vanguard Group Inc5,052,003$42.4M0.00%+1,025,203+25.5%Added
Gilead Sciences, Inc.4,854,443$40.8M2.28%00.0%Unchanged
T. Rowe Price Investment Management, Inc.3,526,359$29.6M0.02%+357,133+11.3%Added
Balyasny Asset Management LLC3,472,207$29.2M0.06%+224,744+6.9%Added
State Street Corp3,365,205$28.3M0.00%+1,982,519+143.4%Added
Paradigm Biocapital Advisors LP3,086,184$25.9M0.77%+3,086,184New
Point72 Asset Management, L.P.2,919,450$24.5M0.05%+2,919,450New
Bain Capital Life Sciences Investors, LLC2,712,008$22.8M1.51%00.0%Unchanged
Adage Capital Partners GP, L.L.C.2,511,000$21.1M0.03%−3,394,349−57.5%Reduced
Janus Henderson Group PLC2,302,274$19.3M0.01%+2,302,274New
Ra Capital Management, L.P.2,000,000$16.8M0.21%00.0%Unchanged
Geode Capital Management, LLC1,882,777$15.8M0.00%+113,864+6.4%Added
Nantahala Capital Management, LLC1,809,948$15.2M0.94%−1,629,646−47.4%Reduced
Goldman Sachs Group Inc1,509,475$12.7M0.00%+1,401,296+1,295.3%Added
Commodore Capital LP1,500,000$12.6M0.62%00.0%Unchanged
Marshall Wace, LLP1,489,518$12.5M0.01%−253,173−14.5%Reduced
Deep Track Capital, LP1,454,562$12.2M0.34%+1,454,562New
Millennium Management LLC1,295,401$10.9M0.01%−476,903−26.9%Reduced
Invesco Ltd.1,031,917$8.67M0.00%+936,624+982.9%Added
Logos Global Management LP950,000$7.98M0.79%+950,000New
Nuveen, LLC928,012$7.80M0.00%+485,049+109.5%Added
Franklin Resources Inc926,904$7.79M0.00%+801,697+640.3%Added
Vivo Capital, LLC776,699$6.52M0.53%+176,699+29.4%Added
Candriam Luxembourg S.C.A.708,812$5.95M0.03%00.0%Unchanged
Bessemer Group Inc708,398$5.95M0.01%+140.0%Added
ArrowMark Colorado Holdings LLC708,385$5.95M0.11%00.0%Unchanged
Dimensional Fund Advisors LP672,735$5.65M0.00%+147,637+28.1%Added
Charles Schwab Investment Management Inc658,292$5.53M0.00%+56,845+9.5%Added
Northern Trust Corp605,561$5.09M0.00%+5,053+0.8%Added
Avoro Capital Advisors LLC545,000$4.58M0.06%+545,000New
D. E. Shaw & Co., Inc.430,379$3.62M0.00%+430,379New
Great Lakes Advisors, LLC423,851$3.56M0.03%+423,851New
Voloridge Investment Management, LLC384,207$3.23M0.01%+384,207New
Barclays PLC365,680$3.07M0.00%+227,030+163.7%Added
Soleus Capital Management, L.P.300,000$2.52M0.13%−430,000−58.9%Reduced
Royal Bank of Canada287,499$2.42M0.00%+35,226+14.0%Added
Wellington Management Group LLP253,288$2.13M0.00%+253,288New
Morgan Stanley251,793$2.12M0.00%−282,828−52.9%Reduced
StemPoint Capital LP245,378$2.06M0.42%+36,578+17.5%Added
Readystate Asset Management LP245,109$2.06M0.10%−173,408−41.4%Reduced
Cubist Systematic Strategies, LLC240,655$2.02M0.03%+240,655New
Fred Alger Management, LLC230,316$1.93M0.01%+38,979+20.4%Added
Congress Asset Management Co228,120$1.92M0.01%+926+0.4%Added
Fisher Asset Management, LLC210,352$1.77M0.00%−13,725−6.1%Reduced
Trexquant Investment LP199,081$1.67M0.02%+199,081New
TRV GP VI, LLC194,174$1.63M1.49%00.0%Unchanged
Bank of New York Mellon Corp192,348$1.62M0.00%+4,351+2.3%Added
UBS Group AG160,478$1.35M0.00%−116,624−42.1%Reduced
Susquehanna Fundamental Investments, LLC157,233$1.32M0.05%−2,604−1.6%Reduced
Bank of America Corp155,447$1.31M0.00%+108,302+229.7%Added
Rafferty Asset Management, LLC145,316$1.22M0.00%+145,316New
Two Sigma Investments, LP144,432$1.21M0.00%+122,214+550.1%Added
Blue Owl Capital Holdings LP119,416$1.00M0.31%−695,000−85.3%Reduced
Rhumbline Advisers107,839$905.8K0.00%−4,434−3.9%Reduced
Alliancebernstein L.P.102,270$859.1K0.00%−3,740−3.5%Reduced
Two Sigma Advisers, LP94,100$790.4K0.00%+94,100New
Susquehanna International Group, LLP88,839$746.2K0.00%−153,608−63.4%Reduced
ExodusPoint Capital Management, LP81,238$682.4K0.01%+81,238New
AQR Capital Management LLC79,175$665.1K0.00%+229+0.3%Added
DekaBank Deutsche Girozentrale60,000$497.0K0.00%00.0%Unchanged
Deutsche Bank AG59,149$496.9K0.00%+6,488+12.3%Added
Renaissance Technologies LLC55,300$464.5K0.00%−10,200−15.6%Reduced
Wells Fargo & Company55,005$462.0K0.00%+5,788+11.8%Added
Tudor Investment Corp Et Al53,572$450.0K0.00%+53,572New
MetLife Investment Management47,726$400.9K0.00%00.0%Unchanged
Price T Rowe Associates Inc40,669$343.0K0.00%+2,268+5.9%Added
Mirae Asset Global ETFs Holdings Ltd.40,398$339.6K0.00%−1,600−3.8%Reduced
Y-Intercept (Hong Kong) Ltd36,963$310.5K0.01%+36,963New
Quadrature Capital Ltd36,189$303.3K0.00%+36,189New
Janney Montgomery Scott LLC36,000$302.0K0.00%−3,500−8.9%Reduced
Creative Planning35,244$296.1K0.00%+35,244New
JPMorgan Chase & Co33,916$284.9K0.00%−32,759−49.1%Reduced
Harvest Investment Services, LLC31,840$267.5K0.05%+31,840New
Profund Advisors LLC31,288$262.8K0.01%+31,288New
Clear Harbor Asset Management, LLC30,300$254.5K0.02%+10.0%Added
J. Goldman & Co LP29,036$243.9K0.01%+29,036New
Intech Investment Management LLC28,152$236.5K0.00%−17,523−38.4%Reduced
Simplicity Wealth,LLC26,961$226.5K0.01%00.0%Unchanged
EverSource Wealth Advisors, LLC26,653$223.9K0.01%+22+0.1%Added
Verition Fund Management LLC24,752$207.9K0.00%+24,752New
Manufacturers Life Insurance Company, The22,694$190.6K0.00%−6,111−21.2%Reduced
Virtus Investment Advisers, Inc.22,532$189.3K0.05%+3,912+21.0%Added
Bridgeway Capital Management, LLC21,500$180.6K0.00%−103,500−82.8%Reduced
Police & Firemen's Retirement System of New Jersey20,548$172.6K0.00%+2,901+16.4%Added
JustInvest LLC20,213$169.8K0.00%−156−0.8%Reduced
China Universal Asset Management Co., Ltd.19,502$163.8K0.01%−2,269−10.4%Reduced
Citigroup Inc18,102$152.1K0.00%−12,189−40.2%Reduced
TD Asset Management Inc18,072$151.8K0.00%+18,072New
Los Angeles Capital Management LLC17,185$144.4K0.00%+6,895+67.0%Added
ProShare Advisors LLC16,230$136.3K0.00%−3,545−17.9%Reduced
New York State Common Retirement Fund15,576$130.8K0.00%+9,000+136.9%Added