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Tango Therapeutics, Inc.

TNGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001819133

In the last 90 days, Tango Therapeutics, Inc. insiders filed 0 open-market purchases and 4 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $6.60B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Tango Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
170
+31 vs. Q3 2025
Shares held
172.4M
+32.7M (+23.4%) vs. Q3 2025
Total value
$1.53B
+$353.7M (+30.1%) vs. Q3 2025
New holders
53
75 more added
Sold out
22
27 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TNGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 170 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 46 institutionsQ4 2021: 58 institutionsQ1 2022: 72 institutionsQ2 2022: 77 institutionsQ3 2022: 87 institutionsQ4 2022: 82 institutionsQ1 2023: 92 institutionsQ2 2023: 89 institutionsQ3 2023: 100 institutionsQ4 2023: 121 institutionsQ1 2024: 126 institutionsQ2 2024: 120 institutionsQ3 2024: 121 institutionsQ4 2024: 138 institutionsQ1 2025: 122 institutionsQ2 2025: 115 institutionsQ3 2025: 141 institutionsQ4 2025: 170 institutionsQ1 2026: 194 institutionsQ2 2026: 247 institutions
Value heldQ4 2025: $1.53B
Q1 2021: $0Q2 2021: $0Q3 2021: $844.9MQ4 2021: $741.0MQ1 2022: $528.2MQ2 2022: $319.1MQ3 2022: $246.8MQ4 2022: $498.4MQ1 2023: $275.9MQ2 2023: $226.8MQ3 2023: $999.9MQ4 2023: $927.1MQ1 2024: $781.2MQ2 2024: $846.0MQ3 2024: $781.2MQ4 2024: $329.2MQ1 2025: $147.0MQ2 2025: $651.7MQ3 2025: $1.18BQ4 2025: $1.53BQ1 2026: $3.78BQ2 2026: $6.60B
Institutions holding TNGX and their total value by quarter
QuarterHoldersValue
Q2 2026247$6.60B
Q1 2026194$3.78B
Q4 2025170$1.53B
Q3 2025141$1.18B
Q2 2025115$651.7M
Q1 2025122$147.0M
Q4 2024138$329.2M
Q3 2024121$781.2M
Q2 2024120$846.0M
Q1 2024126$781.2M
Q4 2023121$927.1M
Q3 2023100$999.9M
Q2 202389$226.8M
Q1 202392$275.9M
Q4 202282$498.4M
Q3 202287$246.8M
Q2 202277$319.1M
Q1 202272$528.2M
Q4 202158$741.0M
Q3 202146$844.9M
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Tango Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding TNGX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd32$00.00%00.0%Unchanged
Essential Partners LLC4$350.00%+4New
SRS Capital Advisors, Inc.8$710.00%−1,194−99.3%Reduced
SBI Securities Co., Ltd.19$1680.00%−35−64.8%Reduced
Rothschild Investment LLC26$2300.00%+6+30.0%Added
Larson Financial Group LLC34$3010.00%+34New
Allworth Financial LP45$3990.00%+7+18.4%Added
Clearstead Advisors, LLC45$3990.00%+45New
WPG Advisers, LLC159$1.41K0.00%+159New
The PNC Financial Services Group, Inc.212$1.88K0.00%00.0%Unchanged
IFP Advisors, Inc233$2.06K0.00%00.0%Unchanged
Flagship Harbor Advisors, LLC300$2.66K0.00%+300New
Caitong International Asset Management Co., Ltd320$2.83K0.00%+320New
Daiwa Securities Group Inc.355$3.00K0.00%00.0%Unchanged
Farther Finance Advisors, LLC355$3.15K0.00%+330+1,320.0%Added
Federated Hermes, Inc.362$3.21K0.00%00.0%Unchanged
Quest Partners LLC375$3.32K0.00%−711−65.5%Reduced
GAMMA Investing LLC477$4.23K0.00%+13+2.8%Added
Optiver Holding B.V.576$5.10K0.00%−38−6.2%Reduced
Advisor Group Holdings, Inc.692$6.13K0.00%+101+17.1%Added
Rockefeller Capital Management L.P.887$7.86K0.00%+765+627.0%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,025$9.00K0.00%+1,025New
TFC Financial Management1,300$11.5K0.00%+500+62.5%Added
Nisa Investment Advisors, LLC1,740$15.4K0.00%00.0%Unchanged
Comerica Bank2,158$19.1K0.00%+2,158New
GF Fund Management Co. Ltd.2,646$23.4K0.00%+252+10.5%Added
Amalgamated Bank3,341$30.0K0.00%+1,723+106.5%Added
Royal Bank of Canada3,682$32.0K0.00%−283,817−98.7%Reduced
Global Retirement Partners, LLC4,004$35.5K0.00%+4,004New
Zurcher Kantonalbank (Zurich Cantonalbank)4,467$39.6K0.00%+4,464+148,800.0%Added
Antipodes Partners Ltd4,513$40.0K0.00%+4,513New
CWM, LLC4,832$43.0K0.00%−38−0.8%Reduced
Sterling Capital Management LLC6,130$54.3K0.00%+1,180+23.8%Added
Mirae Asset Global Investments Co., Ltd.6,544$58.0K0.00%+2,243+52.2%Added
Ameritas Investment Partners, Inc.8,633$76.5K0.00%+2,640+44.1%Added
BNP Paribas Arbitrage, SA9,563$84.7K0.00%−5,527−36.6%Reduced
KLP Kapitalforvaltning AS9,700$85.9K0.00%+9,700New
Russell Investments Group, Ltd.9,794$86.8K0.00%+2,065+26.7%Added
Soleus Capital Management, L.P.10,000$88.6K0.00%−290,000−96.7%Reduced
Victory Capital Management Inc10,206$90.4K0.00%+10,206New
Mercer Global Advisors Inc10,461$92.7K0.00%−865−7.6%Reduced
CI Private Wealth, LLC10,529$93.3K0.00%−971−8.4%Reduced
Pinnacle Wealth Planning Services, Inc.10,782$95.5K0.01%+10,782New
LPL Financial LLC12,000$106.3K0.00%+12,000New
Arizona State Retirement System12,273$108.7K0.00%+12,273New
State Board of Administration of Florida Retirement System12,780$113.2K0.00%00.0%Unchanged
Entropy Technologies, LP14,792$131.1K0.01%+14,792New
Atria Investments LLC14,822$131.3K0.00%+14,822New
Bank of Montreal16,494$146.1K0.00%+16,494New
Bridgefront Capital, LLC19,479$172.6K0.04%+19,479New
Tower Research Capital LLC (TRC)19,741$174.9K0.00%+13,297+206.3%Added
Axq Capital, LP20,268$179.6K0.04%+6,800+50.5%Added
JustInvest LLC20,402$180.8K0.00%+189+0.9%Added
Bridgeway Capital Management, LLC21,500$190.5K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.21,946$194.4K0.01%+2,444+12.5%Added
SG Americas Securities, LLC22,006$195.0K0.00%+22,006New
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.21,872$195.3K0.00%+21,872New
Quantinno Capital Management LP22,339$197.9K0.00%+10,064+82.0%Added
New York State Common Retirement Fund24,576$217.7K0.00%+9,000+57.8%Added
Cantor Fitzgerald, L. P.25,000$221.5K0.01%+25,000New
ProShare Advisors LLC25,384$224.9K0.00%+9,154+56.4%Added
EverSource Wealth Advisors, LLC25,646$227.2K0.01%−1,007−3.8%Reduced
Massachusetts Financial Services Co28,023$248.3K0.00%+28,023New
Police & Firemen's Retirement System of New Jersey28,294$250.7K0.00%+7,746+37.7%Added
Virtus Investment Advisers, Inc.28,452$252.1K0.07%+5,920+26.3%Added
State of Wisconsin Investment Board29,337$259.9K0.00%+29,337New
VARCOV Co.29,486$261.2K0.10%+29,486New
Engineers Gate Manager LP30,599$271.1K0.00%+30,599New
Manufacturers Life Insurance Company, The32,342$286.6K0.00%+9,648+42.5%Added
ExodusPoint Capital Management, LP32,897$291.5K0.00%−48,341−59.5%Reduced
Philadelphia Financial Management of San Francisco, LLC33,291$295.0K0.06%+33,291New
Susquehanna International Group, LLP35,216$312.0K0.00%−53,623−60.4%Reduced
Janney Montgomery Scott LLC36,000$319.0K0.00%00.0%Unchanged
Citigroup Inc36,236$321.1K0.00%+18,134+100.2%Added
XTX Topco Ltd37,838$335.2K0.01%+37,838New
Intech Investment Management LLC38,941$345.0K0.00%+10,789+38.3%Added
Legal & General Group Plc39,430$349.4K0.00%+32,985+511.8%Added
UBS Asset Management Americas Inc41,453$367.3K0.00%+41,453New
Creative Planning41,907$371.3K0.00%+6,663+18.9%Added
SmartHarvest Portfolios, LLC46,123$408.6K0.14%+46,123New
Voya Investment Management LLC47,811$423.6K0.00%+34,346+255.1%Added
California State Teachers Retirement System48,210$427.1K0.00%+43,422+906.9%Added
Canada Pension Plan Investment Board50,400$446.5K0.00%+50,400New
Graham Capital Management, L.P.51,319$454.7K0.02%+51,319New
SEI Investments Co53,927$477.8K0.00%+43,882+436.9%Added
DekaBank Deutsche Girozentrale60,000$502.0K0.00%00.0%Unchanged
JPMorgan Chase & Co56,835$503.6K0.00%+22,919+67.6%Added
Los Angeles Capital Management LLC64,243$512.0K0.00%+47,058+273.8%Added
Price T Rowe Associates Inc58,434$518.0K0.00%+17,765+43.7%Added
Y-Intercept (Hong Kong) Ltd59,330$525.7K0.01%+22,367+60.5%Added
MetLife Investment Management59,692$528.9K0.00%+11,966+25.1%Added
Mirae Asset Global ETFs Holdings Ltd.62,634$551.9K0.00%+22,236+55.0%Added
Tudor Investment Corp Et Al68,251$604.7K0.00%+14,679+27.4%Added
Deutsche Bank AG74,203$657.4K0.00%+15,054+25.5%Added
AQR Capital Management LLC82,233$728.6K0.00%+3,058+3.9%Added
Profund Advisors LLC83,759$742.1K0.02%+52,471+167.7%Added
Swiss National Bank87,800$777.9K0.00%+87,800New
Trexquant Investment LP105,268$932.7K0.01%−93,813−47.1%Reduced
Alliancebernstein L.P.106,490$943.5K0.00%+4,220+4.1%Added
Gsa Capital Partners LLP118,593$1.05M0.09%+118,593New