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Livermore
Livermore
ZHEN

Prime Medicine, Inc.

PRME
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001894562

No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.

Q3 2025 vs. Q2 2025

How the institutions holding Prime Medicine, Inc. changed between Q2 2025 and Q3 2025.

All holders in Q3 2025All holders in Q2 2025

13F holders of PRME: Q2 2025 compared with Q3 2025
MeasureQ2 2025Q3 2025Change
Holders121167+46
Shares58.7M92.3M+33.7M (+57.4%)
Value$145.0M$511.5M+$366.5M (+252.7%)

New holders (53)

Institutions that held Prime Medicine, Inc. at the end of Q3 2025 but not at the end of Q2 2025.

Institutions new to PRME in Q3 2025
InstitutionSharesValue% of portfolio
Woodline Partners LP3,002,482$16.6M0.08%
Ra Capital Management, L.P.3,000,000$16.6M0.20%
D. E. Shaw & Co., Inc.2,215,852$12.3M0.01%
EcoR1 Capital, LLC1,543,326$8.55M0.41%
Adage Capital Partners GP, L.L.C.771,361$4.27M0.01%
Wellington Management Group LLP205,325$1.14M0.00%
Man Group plc189,588$1.05M0.00%
JBF Capital, Inc.188,900$1.05M0.15%
DnB Asset Management AS182,133$1.01M0.00%
Voloridge Investment Management, LLC170,021$941.9K0.00%
Ikarian Capital, LLC150,000$831.0K0.19%
Steward Partners Investment Advisory, LLC126,387$700.2K0.00%
Keystone Financial Group70,855$392.5K0.03%
Tudor Investment Corp Et Al62,981$348.9K0.00%
Brevan Howard Capital Management LP62,242$344.8K0.00%
Ameriprise Financial Inc61,572$341.1K0.00%
Engineers Gate Manager LP55,597$308.0K0.00%
Boothbay Fund Management, LLC55,050$305.0K0.01%
Balyasny Asset Management LLC47,873$265.2K0.00%
Jain Global LLC44,849$248.5K0.00%
IvyRock Asset Management (HK) Ltd41,800$231.6K0.10%
CI Private Wealth, LLC38,777$214.8K0.00%
PEAK6 LLC35,063$194.2K0.00%
ExodusPoint Capital Management, LP33,494$185.6K0.00%
LPL Financial LLC31,039$172.0K0.00%
Thompson Davis & Co., Inc.27,573$152.8K0.09%
Bank of Nova Scotia25,500$141.3K0.00%
Abacus Planning Group, Inc.25,188$139.5K0.02%
Turtle Creek Wealth Advisors, LLC25,000$138.5K0.01%
Nomura Holdings Inc24,915$138.0K0.00%
Polymer Capital Management (US) LLC20,791$115.2K0.02%
Owen LaRue, LLC19,032$105.4K0.04%
Mariner, LLC18,219$100.9K0.00%
Shelton Wealth Management, LLC17,332$96.0K0.04%
Sanctuary Advisors, LLC14,323$79.3K0.00%
Hudson Bay Capital Management LP13,025$72.2K0.00%
Wiley Bros.-Aintree Capital, LLC11,848$70.6K0.00%
Victory Capital Management Inc10,190$56.5K0.00%
Quadrature Capital Ltd10,182$56.3K0.00%
Sterling Investment Advisors, Ltd.10,000$55.4K0.01%
Jones Financial Companies LLLP9,575$49.0K0.00%
NBC Securities, Inc.7,500$41.5K0.00%
SRS Capital Advisors, Inc.5,406$29.9K0.00%
California State Teachers Retirement System3,654$20.2K0.00%
Financial Connections Group, Inc.3,712$20.0K0.01%
FSA Wealth Management LLC1,500$8.31K0.00%
Rockefeller Capital Management L.P.1,139$6.31K0.00%
Allworth Financial LP1,006$5.57K0.00%
GWM Advisors LLC1,000$5.54K0.00%
Corsicana & Co.1,000$5.54K0.00%
Optiver Holding B.V.898$4.97K0.00%
Scarborough Advisors, LLC505$2.80K0.00%
Sunbelt Securities, Inc.80$4430.00%

Sold out (7)

Institutions that held Prime Medicine, Inc. at the end of Q2 2025 and filed for Q3 2025 without it.

Institutions that sold out of PRME in Q3 2025
InstitutionShares, Q2 2025Value, Q2 2025
Jaffetilchin Investment Partners, LLC37,744$93.2K
SG Americas Securities, LLC27,919$69.0K
CIBC World Markets Inc.14,326$35.4K
R Squared Ltd12,519$30.9K
State Board of Administration of Florida Retirement System11,420$28.2K
Eqis Capital Management, Inc.10,432$25.8K
Fogel Capital Management, Inc.10,000$24.7K