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Oruka Therapeutics, Inc.

ORKA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000907654

In the last 90 days, Oruka Therapeutics, Inc. insiders filed 0 open-market purchases and 16 sales; 255 institutions reported holding it in 13F filings for Q2 2026, worth $7.05B in total; Viking Global Investors is the only superinvestor holding it.

13F holders, Q1 2026

Institutional positions in Oruka Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
184
+43 vs. Q4 2025
Shares held
52.0M
+1.62M (+3.2%) vs. Q4 2025
Total value
$2.55B
+$1.02B (+67.0%) vs. Q4 2025
New holders
63
64 more added
Sold out
20
31 more reduced

2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ORKA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 184 institutions
Q1 2021: 17 institutionsQ2 2021: 17 institutionsQ3 2021: 19 institutionsQ4 2021: 21 institutionsQ1 2022: 22 institutionsQ2 2022: 24 institutionsQ3 2022: 25 institutionsQ4 2022: 22 institutionsQ1 2023: 26 institutionsQ2 2023: 23 institutionsQ3 2023: 21 institutionsQ4 2023: 25 institutionsQ1 2024: 23 institutionsQ2 2024: 32 institutionsQ3 2024: 42 institutionsQ4 2024: 66 institutionsQ1 2025: 71 institutionsQ2 2025: 81 institutionsQ3 2025: 105 institutionsQ4 2025: 143 institutionsQ1 2026: 184 institutionsQ2 2026: 255 institutions
Value heldQ1 2026: $2.55B
Q1 2021: $3.20MQ2 2021: $4.16MQ3 2021: $4.53MQ4 2021: $2.41MQ1 2022: $2.60MQ2 2022: $4.17MQ3 2022: $4.58MQ4 2022: $6.19MQ1 2023: $5.02MQ2 2023: $5.75MQ3 2023: $6.55MQ4 2023: $12.7MQ1 2024: $12.7MQ2 2024: $49.4MQ3 2024: $604.2MQ4 2024: $606.6MQ1 2025: $326.1MQ2 2025: $386.0MQ3 2025: $875.8MQ4 2025: $1.60BQ1 2026: $2.55BQ2 2026: $7.05B
Institutions holding ORKA and their total value by quarter
QuarterHoldersValue
Q2 2026255$7.05B
Q1 2026184$2.55B
Q4 2025143$1.60B
Q3 2025105$875.8M
Q2 202581$386.0M
Q1 202571$326.1M
Q4 202466$606.6M
Q3 202442$604.2M
Q2 202432$49.4M
Q1 202423$12.7M
Q4 202325$12.7M
Q3 202321$6.55M
Q2 202323$5.75M
Q1 202326$5.02M
Q4 202222$6.19M
Q3 202225$4.58M
Q2 202224$4.17M
Q1 202222$2.60M
Q4 202121$2.41M
Q3 202119$4.53M
Q2 202117$4.16M
Q1 202117$3.20M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Oruka Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding ORKA in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Squarepoint Ops LLC24,463$1.20M0.00%−3,208−11.6%Reduced
Alliancebernstein L.P.40,400$1.22M0.00%+2,600+6.9%Added
Schroder Investment Management Group29,184$1.33M0.00%00.0%Unchanged
Y-Intercept (Hong Kong) Ltd36,912$1.81M0.03%+36,912New
Alps Advisors Inc39,404$1.93M0.01%−347−0.9%Reduced
Rafferty Asset Management, LLC40,487$1.99M0.01%+2,002+5.2%Added
Voleon Capital Management LP40,539$1.99M0.04%+16,991+72.2%Added
Martingale Asset Management L P42,732$2.10M0.05%+42,732New
Swiss National Bank43,000$2.11M0.00%00.0%Unchanged
Fred Alger Management, LLC43,841$2.15M0.01%+43,841New
Russell Investments Group, Ltd.45,459$2.23M0.00%+42,418+1,394.9%Added
Rhumbline Advisers46,356$2.27M0.00%+5,339+13.0%Added
EAM Investors, LLC59,946$2.94M0.34%+59,946New
Palo Alto Investors LP59,985$2.94M0.45%00.0%Unchanged
Superstring Capital Management LP63,591$3.12M2.23%+63,591New
Voya Investment Management LLC66,600$3.27M0.00%+24,097+56.7%Added
Boothbay Fund Management, LLC67,481$3.31M0.08%+67,481New
Secure Asset Management, LLC72,422$3.55M0.56%−9,242−11.3%Reduced
Manufacturers Life Insurance Company, The72,563$3.56M0.00%+11,205+18.3%Added
American Century Companies Inc74,386$3.65M0.00%+17,306+30.3%Added
B Group, Inc.75,000$3.68M2.73%00.0%Unchanged
Standard Life Aberdeen plc75,680$3.71M0.01%00.0%Unchanged
TD Asset Management Inc75,696$3.71M0.00%−4,200−5.3%Reduced
HighVista Strategies LLC78,911$3.87M1.07%+78,911New
Ensign Peak Advisors, Inc79,380$3.89M0.01%+79,380New
Barclays PLC85,737$4.21M0.00%−87,592−50.5%Reduced
Nuveen, LLC86,938$4.26M0.00%+591+0.7%Added
Invesco Ltd.97,042$4.76M0.00%−46,079−32.2%Reduced
Bank of America Corp100,091$4.91M0.00%−39,181−28.1%Reduced
ExodusPoint Capital Management, LP101,354$4.97M0.05%+101,354New
Bank of New York Mellon Corp106,883$5.24M0.00%−7,290−6.4%Reduced
Dimensional Fund Advisors LP113,009$5.54M0.00%+113,009New
Kalehua Capital Management LLC118,524$5.81M4.11%00.0%Unchanged
Wellington Management Group LLP121,225$5.95M0.00%+36,509+43.1%Added
Kennedy Capital Management, Inc.126,366$6.20M0.13%+77,680+159.6%Added
Sio Capital Management, LLC132,496$6.50M0.94%+14,370+12.2%Added
Moody Aldrich Partners LLC135,061$6.62M1.19%+8,249+6.5%Added
Longaeva Partners L.P.136,884$6.71M0.32%+8,774+6.8%Added
Deutsche Bank AG140,789$6.91M0.00%+21,460+18.0%Added
Jones Hill Capital LP140,843$6.91M1.48%+140,843New
Silverarc Capital Management, LLC150,908$7.40M0.87%+150,908New
PFM Health Sciences, LP174,052$8.54M0.90%+174,052New
Morgan Stanley175,454$8.61M0.00%+53,256+43.6%Added
Jennison Associates LLC176,680$8.67M0.01%+176,680New
Great Point Partners LLC183,330$8.99M2.20%00.0%Unchanged
Alyeska Investment Group, L.P.184,863$9.07M0.03%+84,863+84.9%Added
Holocene Advisors, LP185,513$9.10M0.02%+185,513New
Adage Capital Partners GP, L.L.C.190,030$9.32M0.01%+190,030New
Cable Car Capital LLC200,000$9.81M3.39%−200,000−50.0%Reduced
UBS Group AG212,271$10.4M0.00%−58,742−21.7%Reduced
Atika Capital Management LLC229,900$11.3M1.78%+229,900New
Ikarian Capital, LLC242,021$11.9M1.70%+242,021New
Goldman Sachs Group Inc246,711$12.1M0.00%+153,716+165.3%Added
Vanguard Fiduciary Trust Co257,071$12.6M0.00%+257,071New
Northern Trust Corp299,044$14.7M0.00%+18,140+6.5%Added
Westfield Capital Management Co LP313,130$15.4M0.06%+313,130New
Charles Schwab Investment Management Inc321,949$15.8M0.00%−7,547−2.3%Reduced
Vanguard Portfolio Management LLC350,892$17.2M0.00%+350,892New
Candriam Luxembourg S.C.A.411,006$20.2M0.10%+10,497+2.6%Added
Sr One Capital Management, LP430,330$21.1M2.31%00.0%Unchanged
Synergy Financial Management, LLC476,196$23.4M2.48%+17,250+3.8%Added
Affinity Asset Advisors, LLC499,673$24.5M1.44%−302,669−37.7%Reduced
Bellevue Group AG507,008$24.9M0.59%+507,008New
Cormorant Asset Management, LP533,340$26.2M1.32%00.0%Unchanged
Woodline Partners LP574,882$28.2M0.11%+329+0.1%Added
Price T Rowe Associates Inc727,449$35.7M0.00%+78,103+12.0%Added
Avidity Partners Management LP760,424$37.3M7.55%+100,000+15.1%Added
Mercer Global Advisors Inc802,470$39.4M0.06%+57,193+7.7%Added
Geode Capital Management, LLC954,867$46.8M0.00%+12,360+1.3%Added
Franklin Resources Inc1,004,056$49.2M0.01%+65,635+7.0%Added
Citadel Advisors LLC1,007,537$49.4M0.04%+281,419+38.8%Added
Polar Capital Holdings Plc1,047,693$51.4M0.22%+69,405+7.1%Added
Perceptive Advisors LLC1,395,501$68.4M1.35%−81,000−5.5%Reduced
Remedium Capital Partners, LLC1,565,661$76.8M27.31%+13,247+0.9%Added
State Street Corp1,613,461$79.1M0.00%+229,614+16.6%Added
Vanguard Capital Management LLC1,859,631$91.2M0.00%+1,859,631New
Deep Track Capital, LP2,034,203$99.8M2.06%−127,307−5.9%Reduced
RTW Investments, LP2,058,148$101.0M1.00%00.0%Unchanged
Paradigm Biocapital Advisors LP2,320,316$113.8M2.33%+610,000+35.7%Added
Viking Global Investors LPSuperinvestorViking Global Investors2,666,690$130.8M0.37%00.0%Unchanged
BlackRock, Inc.3,527,087$173.0M0.00%−12,328−0.3%Reduced
Fairmount Funds Management LLC3,705,262$181.7M13.13%00.0%Unchanged
VR Adviser, LLC4,148,428$203.5M7.60%00.0%Unchanged
FMR LLC7,431,403$364.5M0.02%+170,019+2.3%Added
Commodore Capital LP0$00.00%−1,753,054−100.0%Sold out
Avoro Capital Advisors LLC0$00.00%−1,333,340−100.0%Sold out
Blackstone Group Inc.0$00.00%−1,165,408−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−600,000−100.0%Sold out
Braidwell LP0$00.00%−84,795−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−76,415−100.0%Sold out
Millennium Management LLC0$00.00%−58,723−100.0%Sold out
Verition Fund Management LLC0$00.00%−35,710−100.0%Sold out
Financial Enhancement Group LLC0$00.00%−31,293−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−20,000−100.0%Sold out
Quest Partners LLC0$00.00%−14,901−100.0%Sold out
Altfest L J & Co Inc0$00.00%−10,857−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−9,416−100.0%Sold out
SG Americas Securities, LLC0$00.00%−8,275−100.0%Sold out
Seven Fleet Capital Management LP0$00.00%−5,240−100.0%Sold out
Amalgamated Bank0$00.00%−1,212−100.0%Sold out