OnKure Therapeutics, Inc.
OKUR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001637715
In the last 90 days, OnKure Therapeutics, Inc. insiders filed 0 open-market purchases and 2 sales; 75 institutions reported holding it in 13F filings for Q2 2026, worth $159.0M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in OnKure Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 51
- +9 vs. Q4 2025
- Shares held
- 27.5M
- +17.3M (+169.0%) vs. Q4 2025
- Total value
- $113.9M
- +$84.3M (+285.1%) vs. Q4 2025
- New holders
- 18
- 12 more added
- Sold out
- 9
- 14 more reduced
2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OKUR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 75 | $159.0M |
| Q1 2026 | 51 | $113.9M |
| Q4 2025 | 44 | $32.0M |
| Q3 2025 | 42 | $28.1M |
| Q2 2025 | 49 | $25.8M |
| Q1 2025 | 47 | $50.1M |
| Q4 2024 | 51 | $99.2M |
| Q3 2024 | 51 | $49.0M |
| Q2 2024 | 66 | $41.3M |
| Q1 2024 | 62 | $45.4M |
| Q4 2023 | 68 | $40.4M |
| Q3 2023 | 58 | $208.3M |
| Q2 2023 | 52 | $168.9M |
| Q1 2023 | 35 | $102.0M |
| Q4 2022 | 32 | $38.4M |
| Q3 2022 | 33 | $55.1M |
| Q2 2022 | 33 | $43.3M |
| Q1 2022 | 41 | $50.8M |
| Q4 2021 | 39 | $148.9M |
| Q3 2021 | 38 | $136.7M |
| Q2 2021 | 38 | $170.6M |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding OnKure Therapeutics, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 3,998,333 | $16.6M | 0.18% | +3,998,333 | New |
| Acorn Capital Advisors, LLC | 2,839,674 | $11.8M | 3.34% | 00.0% | Unchanged |
| StepStone Group LP | 2,660,612 | $11.0M | 5.31% | +2,168,674+440.8% | Added |
| ADAR1 Capital Management, LLC | 2,434,941 | $10.1M | 0.61% | +1,420,783+140.1% | Added |
| Prosight Management, LP | 2,154,381 | $8.92M | 1.46% | +1,337,472+163.7% | Added |
| BVF Inc | 1,978,972 | $8.19M | 0.26% | +1,978,972 | New |
| Vivo Capital, LLC | 1,927,710 | $7.98M | 0.66% | +1,927,710 | New |
| Vestal Point Capital, LP | 1,839,819 | $7.62M | 0.21% | +1,204,819+189.7% | Added |
| Foresite Capital Management VI LLC | 1,445,783 | $5.99M | 1.30% | +1,445,783 | New |
| Adage Capital Partners GP, L.L.C. | 1,204,819 | $4.99M | 0.01% | +1,204,819 | New |
| Sio Capital Management, LLC | 1,078,965 | $4.47M | 0.64% | +1,078,965 | New |
| Vanguard Capital Management LLC | 582,477 | $2.41M | 0.00% | +582,477 | New |
| NEA Management Company, LLC | 478,548 | $1.98M | 0.11% | 00.0% | Unchanged |
| Rosalind Advisors, Inc. | 443,763 | $1.84M | 0.75% | −286,725−39.3% | Reduced |
| Renaissance Technologies LLC | 377,250 | $1.56M | 0.00% | +129,900+52.5% | Added |
| Carlyle Group Inc. | 269,895 | $1.12M | 0.01% | 00.0% | Unchanged |
| DV Trading LLC | 240,963 | $997.6K | 0.09% | +240,963 | New |
| Affinity Asset Advisors, LLC | 240,963 | $997.6K | 0.06% | +240,963 | New |
| Sofinnova Investments, Inc. | 141,700 | $586.6K | 0.03% | +141,700 | New |
| Stonepine Capital Management, LLC | 132,578 | $548.9K | 0.48% | +132,578 | New |
| Shay Capital LLC | 132,219 | $547.4K | 0.08% | −648,642−83.1% | Reduced |
| Cantor Fitzgerald, L. P. | 99,900 | $413.6K | 0.01% | −345,178−77.6% | Reduced |
| Geode Capital Management, LLC | 98,750 | $408.8K | 0.00% | +21,281+27.5% | Added |
| Rangeley Capital, LLC | 95,000 | $393.3K | 0.43% | −50,000−34.5% | Reduced |
| Aisling Capital Management LP | 88,607 | $366.8K | 0.08% | 00.0% | Unchanged |
| BlackRock, Inc. | 49,587 | $205.3K | 0.00% | −3,091−5.9% | Reduced |
| GWM Advisors LLC | 44,551 | $184.4K | 0.00% | +44,551 | New |
| Vanguard Fiduciary Trust Co | 43,371 | $179.6K | 0.00% | +43,371 | New |
| Aldebaran Capital, LLC | 40,419 | $167.3K | 0.13% | −865−2.1% | Reduced |
| Citadel Advisors LLC | 37,587 | $155.6K | 0.00% | −185,538−83.2% | Reduced |
| HRT Financial LP | 37,055 | $153.0K | 0.00% | +37,055 | New |
| Marshall Wace, LLP | 36,444 | $150.9K | 0.00% | +36,444 | New |
| XTX Topco Ltd | 34,129 | $141.3K | 0.00% | +16,328+91.7% | Added |
| Millennium Management LLC | 30,499 | $126.3K | 0.00% | +30,499 | New |
| Jane Street Group, LLC | 26,812 | $111.0K | 0.00% | +7,398+38.1% | Added |
| Barclays PLC | 25,000 | $103.5K | 0.00% | −2,242−8.2% | Reduced |
| Two Sigma Investments, LP | 24,262 | $100.4K | 0.00% | +12,942+114.3% | Added |
| Gsa Capital Partners LLP | 22,224 | $92.0K | 0.01% | −23,724−51.6% | Reduced |
| Northern Trust Corp | 19,903 | $82.4K | 0.00% | 00.0% | Unchanged |
| Bridgeway Capital Management, LLC | 16,293 | $67.5K | 0.00% | −3,207−16.4% | Reduced |
| Morgan Stanley | 14,327 | $59.3K | 0.00% | −10,635−42.6% | Reduced |
| Wells Fargo & Company | 13,500 | $55.9K | 0.00% | +2,500+22.7% | Added |
| State Street Corp | 13,462 | $55.7K | 0.00% | +13,462 | New |
| UBS Group AG | 3,395 | $14.1K | 0.00% | +2,187+181.0% | Added |
| Vanguard Global Advisers, LLC | 745 | $3.08K | 0.00% | +745 | New |
| BNP Paribas Arbitrage, SA | 281 | $1.16K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 230 | $1.00K | 0.00% | +128+125.5% | Added |
| Trust Co of Toledo NA | 136 | $563 | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 90 | $372 | 0.00% | −19−17.4% | Reduced |
| JPMorgan Chase & Co | 45 | $171 | 0.00% | −500−91.7% | Reduced |
| Citigroup Inc | 1 | $4 | 0.00% | −3,728−100.0% | Reduced |
| Highbridge Capital Management LLC | 0 | $0 | 0.00% | −542,361−100.0% | Sold out |
| Sphera Funds Management Ltd. | 0 | $0 | 0.00% | −60,454−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −26,608−100.0% | Sold out |
| HSBC Holdings PLC | 0 | $0 | 0.00% | −19,973−100.0% | Sold out |
| Torren Management, LLC | 0 | $0 | 0.00% | −504−100.0% | Sold out |
| FMR LLC | 0 | $0 | 0.00% | −400−100.0% | Sold out |
| Bank of America Corp | 0 | $0 | 0.00% | −141−100.0% | Sold out |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −56−100.0% | Sold out |
| Northwestern Mutual Wealth Management Co | 0 | $0 | 0.00% | −2−100.0% | Sold out |
| Vanguard Group Inc | – | – | – | – | Not filed |
| Kotler Kevin | – | – | – | – | Not filed |