OnKure Therapeutics, Inc.
OKUR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001637715
In the last 90 days, OnKure Therapeutics, Inc. insiders filed 0 open-market purchases and 2 sales; 75 institutions reported holding it in 13F filings for Q2 2026, worth $159.0M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in OnKure Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 44
- +2 vs. Q3 2025
- Shares held
- 11.1M
- +836.4K (+8.2%) vs. Q3 2025
- Total value
- $32.0M
- +$3.87M (+13.8%) vs. Q3 2025
- New holders
- 8
- 10 more added
- Sold out
- 6
- 15 more reduced
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OKUR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 75 | $159.0M |
| Q1 2026 | 51 | $113.9M |
| Q4 2025 | 44 | $32.0M |
| Q3 2025 | 42 | $28.1M |
| Q2 2025 | 49 | $25.8M |
| Q1 2025 | 47 | $50.1M |
| Q4 2024 | 51 | $99.2M |
| Q3 2024 | 51 | $49.0M |
| Q2 2024 | 66 | $41.3M |
| Q1 2024 | 62 | $45.4M |
| Q4 2023 | 68 | $40.4M |
| Q3 2023 | 58 | $208.3M |
| Q2 2023 | 52 | $168.9M |
| Q1 2023 | 35 | $102.0M |
| Q4 2022 | 32 | $38.4M |
| Q3 2022 | 33 | $55.1M |
| Q2 2022 | 33 | $43.3M |
| Q1 2022 | 41 | $50.8M |
| Q4 2021 | 39 | $148.9M |
| Q3 2021 | 38 | $136.7M |
| Q2 2021 | 38 | $170.6M |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding OnKure Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Acorn Capital Advisors, LLC | 2,839,674 | $8.24M | 2.79% | 00.0% | Unchanged |
| ADAR1 Capital Management, LLC | 1,014,158 | $2.94M | 0.22% | +1,014,158 | New |
| Prosight Management, LP | 816,909 | $2.37M | 0.49% | +548,950+204.9% | Added |
| Shay Capital LLC | 780,861 | $2.26M | 0.37% | −137,073−14.9% | Reduced |
| Rosalind Advisors, Inc. | 730,488 | $2.12M | 0.81% | +730,488 | New |
| Vestal Point Capital, LP | 635,000 | $1.84M | 0.07% | 00.0% | Unchanged |
| Vanguard Group Inc | 626,593 | $1.82M | 0.00% | −51,633−7.6% | Reduced |
| Highbridge Capital Management LLC | 542,361 | $1.57M | 0.07% | −107,857−16.6% | Reduced |
| NEA Management Company, LLC | 478,548 | $1.39M | 0.07% | 00.0% | Unchanged |
| StepStone Group LP | 491,938 | $1.35M | 0.72% | 00.0% | Unchanged |
| Cantor Fitzgerald, L. P. | 445,078 | $1.29M | 0.04% | −46,785−9.5% | Reduced |
| Carlyle Group Inc. | 269,895 | $771.9K | 0.01% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 247,350 | $717.3K | 0.00% | +71,600+40.7% | Added |
| Citadel Advisors LLC | 223,125 | $647.1K | 0.00% | −793,488−78.1% | Reduced |
| Kotler Kevin | 197,691 | $573.3K | 0.42% | +197,691 | New |
| Rangeley Capital, LLC | 145,000 | $420.5K | 0.36% | −10,490−6.7% | Reduced |
| Aisling Capital Management LP | 88,607 | $257.0K | 0.05% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 77,469 | $224.7K | 0.00% | −7,426−8.7% | Reduced |
| Sphera Funds Management Ltd. | 60,454 | $175.3K | 0.04% | 00.0% | Unchanged |
| BlackRock, Inc. | 52,678 | $152.8K | 0.00% | −512,158−90.7% | Reduced |
| Gsa Capital Partners LLP | 45,948 | $133.0K | 0.01% | −13,276−22.4% | Reduced |
| Aldebaran Capital, LLC | 41,284 | $119.7K | 0.11% | −2,713−6.2% | Reduced |
| Barclays PLC | 27,242 | $79.0K | 0.00% | +26,621+4,286.8% | Added |
| Two Sigma Advisers, LP | 26,608 | $77.2K | 0.00% | 00.0% | Unchanged |
| Morgan Stanley | 24,962 | $72.4K | 0.00% | +7,748+45.0% | Added |
| HSBC Holdings PLC | 19,973 | $57.7K | 0.00% | +19,973 | New |
| Northern Trust Corp | 19,903 | $57.7K | 0.00% | −2,607−11.6% | Reduced |
| Bridgeway Capital Management, LLC | 19,500 | $56.5K | 0.00% | 00.0% | Unchanged |
| Jane Street Group, LLC | 19,414 | $56.3K | 0.00% | +19,414 | New |
| XTX Topco Ltd | 17,801 | $51.6K | 0.00% | +17,801 | New |
| Two Sigma Investments, LP | 11,320 | $32.8K | 0.00% | −14,115−55.5% | Reduced |
| Wells Fargo & Company | 11,000 | $31.9K | 0.00% | +1,500+15.8% | Added |
| Citigroup Inc | 3,729 | $10.8K | 0.00% | +405+12.2% | Added |
| UBS Group AG | 1,208 | $3.50K | 0.00% | +1,003+489.3% | Added |
| JPMorgan Chase & Co | 545 | $1.58K | 0.00% | +122+28.8% | Added |
| Torren Management, LLC | 504 | $1.46K | 0.00% | +504 | New |
| FMR LLC | 400 | $1.16K | 0.00% | +350+700.0% | Added |
| BNP Paribas Arbitrage, SA | 281 | $815 | 0.00% | −83−22.8% | Reduced |
| Bank of America Corp | 141 | $409 | 0.00% | −755−84.3% | Reduced |
| Trust Co of Toledo NA | 136 | $394 | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 109 | $316 | 0.00% | +9+9.0% | Added |
| Group One Trading, L.P. | 56 | $162 | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 2 | $6 | 0.00% | +2 | New |
| Royal Bank of Canada | 102 | $0 | 0.00% | −88−46.3% | Reduced |
| Tang Capital Management LLC | 0 | $0 | 0.00% | −116,395−100.0% | Sold out |
| China Universal Asset Management Co., Ltd. | 0 | $0 | 0.00% | −2,251−100.0% | Sold out |
| Tower Research Capital LLC (TRC) | 0 | $0 | 0.00% | −1,935−100.0% | Sold out |
| Mirae Asset Global Investments Co., Ltd. | 0 | $0 | 0.00% | −497−100.0% | Sold out |
| GF Fund Management Co. Ltd. | 0 | $0 | 0.00% | −271−100.0% | Sold out |
| MAI Capital Management | 0 | $0 | 0.00% | −6−100.0% | Sold out |