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OnKure Therapeutics, Inc.

OKUR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001637715

In the last 90 days, OnKure Therapeutics, Inc. insiders filed 0 open-market purchases and 2 sales; 75 institutions reported holding it in 13F filings for Q2 2026, worth $159.0M in total; no superinvestor holds it.

Holders of 5% or more of OKUR

Holders whose latest Schedule 13D or 13G filing reports 5% or more of OnKure Therapeutics, Inc., largest stake first. The change is against the holder's previous filing.

Holders of 5% or more of OKUR
HolderLatest formStakeChangeFirst filedLatest filingFiling
AI Biotechnology LLC13D19.99%9.09M sharesNewApr 7, 20261 filingApr 7, 2026SEC
Ra Capital Management, L.P.13G9.90%4.04M sharesNewApr 7, 20261 filingApr 7, 2026SEC
Acorn Bioventures, L.P.13G9.50%3.92M shares−12.60 ppfrom 22.10%Oct 9, 20244 filingsApr 1, 2026SEC
Biotechnology Value Fund L P13G/A8.00%3.24M shares+2.70 ppfrom 5.30%May 27, 20262 filingsAug 14, 2026SEC
StepStone Group LP13G6.60%2.66M sharesNewApr 7, 20261 filingApr 7, 2026SEC
Shay Capital LLC13G6.30%810.2K sharesNewMay 29, 20251 filingMay 29, 2025SEC
ADAR1 Capital Management, LLC13G/A5.50%2.24M shares−0.50 ppfrom 6.00%Feb 17, 20263 filingsAug 14, 2026SEC
Cantor Fitzgerald & Co.13G5.20%669.5K sharesNewAug 14, 20251 filingAug 14, 2025SEC

Stakes are as of each holder's latest filing. Holders whose last filing was in the old format (before December 18, 2024) have no stake on record and are not listed, and after an acquisition or delisting holders usually stop filing.

13D and 13G filings

61 Schedule 13D and 13G filings on OnKure Therapeutics, Inc., newest first, including old-format filings without a stake.

Schedule 13D and 13G filings on OKUR
Filed (ET)FilerFormStakeChangeEvent dateFiling
Aug 14, 20265:01 PM ETADAR1 Capital Management, LLCand 2 others13G/A5.50%2.24M shares−0.50 ppfrom 6.00%Jun 30, 2026SEC
Aug 14, 20264:15 PM ETBiotechnology Value Fund L Pand 9 others13G/A8.00%3.24M shares+2.70 ppfrom 5.30%Jun 30, 2026SEC
Aug 14, 20264:15 PM ETTrails Edge Capital Partners, LPand 2 others13G/A3.60%1.44M shares−2.40 ppfrom 6.00%Below 5%Jun 30, 2026SEC
Aug 10, 20268:51 AM ETProsight Management, LPand 4 others13G/A2.40%979.0K shares−3.40 ppfrom 5.80%Below 5%Jun 30, 2026SEC
May 27, 20264:37 PM ETBiotechnology Value Fund L Pand 9 others13G5.30%2.13M sharesNewMay 19, 2026SEC
May 15, 20268:20 PM ETADAR1 Capital Management, LLCand 2 others13G/A6.00%2.43M shares−1.90 ppfrom 7.90%Mar 31, 2026SEC
Apr 7, 20269:14 PM ETAI Biotechnology LLCand 3 others13D19.99%9.09M sharesNewMar 31, 2026SEC
Apr 7, 20267:21 PM ETStepStone Group LPand 2 others13G6.60%2.66M sharesNewMar 31, 2026SEC
Apr 7, 20264:30 PM ETTrails Edge Capital Partners, LPand 2 others13G6.00%2.41M sharesNewMar 31, 2026SEC
Apr 7, 20264:13 PM ETRa Capital Management, L.P.and 3 others13G9.90%4.04M sharesNewMar 31, 2026SEC
Apr 1, 202611:17 AM ETAcorn Bioventures, L.P.and 4 others13G9.50%3.92M shares−12.60 ppfrom 22.10%Mar 27, 2026SEC
Feb 17, 20268:15 PM ETADAR1 Capital Management, LLCand 2 others13G7.90%1.01M sharesNewDec 31, 2025SEC
Feb 17, 20264:53 PM ETCitadel Advisors LLCand 6 others13G/A1.70%223.1K shares–Below 5%Dec 31, 2025SEC
Feb 17, 20264:10 PM ETHighbridge Capital Management LLC13G/A4.20%542.4K shares−1.00 ppfrom 5.20%Below 5%Dec 31, 2025SEC
Jan 30, 20262:21 PM ETVanguard Group Inc13G/A4.87%626.6K shares−0.71 ppfrom 5.58%Below 5%Dec 31, 2025SEC
Nov 28, 20258:15 AM ETProsight Management, LPand 4 others13G5.80%745.6K sharesNewNov 24, 2025SEC
Aug 14, 20255:28 PM ETSamsara BioCapital, L.P.and 2 others13G/A0.00%0 shares–Below 5%Jun 30, 2025SEC
Aug 14, 20255:20 PM ETPerceptive Advisors LLCand 2 others13G/A0.00%0 shares–Below 5%Jun 30, 2025SEC
Aug 14, 20254:09 PM ETHighbridge Capital Management LLC13G5.20%663.6K shares+2.00 ppfrom 3.20%Jun 30, 2025SEC
Aug 14, 20254:05 PM ETCantor Fitzgerald & Co.and 3 others13G5.20%669.5K sharesNewJun 30, 2025SEC
May 30, 20253:57 PM ETAcorn Bioventures, L.P.and 4 others13D/A22.10%2.84M shares0.00 ppfrom 22.10%May 15, 2025SEC
May 29, 20254:33 PM ETShay Capital LLCand 1 other13G6.30%810.2K sharesNewMay 15, 2025SEC
May 22, 20254:49 PM ETAcorn Bioventures, L.P.and 4 others13D22.10%2.84M shares–May 15, 2025SEC
May 19, 20253:02 PM ETCormorant Asset Management, LPand 1 other13G/A0.00%0 shares–Below 5%May 15, 2025SEC
Feb 14, 20258:48 AM ETDeep Track Capital, LPand 2 others13G/A4.14%524.0K shares–Below 5%Dec 31, 2024SEC
Feb 7, 20254:15 PM ETHighbridge Capital Management LLC13G/A3.20%399.7K shares–Below 5%Dec 31, 2024SEC
Feb 6, 20259:09 PM ETLundbeckfond Invest A/Sand 1 other13G/A1.60%203.1K shares–Below 5%Dec 31, 2024SEC
Jan 31, 20259:56 AM ETVanguard Group Inc13G5.58%706.7K sharesNewDec 31, 2024SEC
Jan 21, 20256:38 PM ETRiverVest Venture Fund III, L.P.and 11 others13D/A1.55%196.2K shares–Below 5%Jan 16, 2025SEC
Nov 14, 2024Tang Capital Management LLC13G/AOld format–––SEC
Nov 14, 2024Highbridge Capital Management LLC13GOld format–New–SEC
Oct 28, 2024Octagon Capital Advisors LP13G/AOld format–––SEC
Oct 23, 2024Deep Track Capital, LP13G/AOld format–––SEC
Oct 16, 2024Cormorant Asset Management, LP13G/AOld format–––SEC
Oct 11, 2024Deep Track Capital, LP13GOld format–New–SEC
Oct 11, 2024Citadel Advisors LLC13GOld format–New–SEC
Oct 11, 2024Samsara BioCapital, L.P.13GOld format–New–SEC
Oct 11, 2024Cormorant Asset Management, LP13GOld format–New–SEC
Oct 10, 20244:30 PM ETCarlyle Group Inc.13D/AOld format–––SEC
Oct 10, 2024Perceptive Advisors LLC13GOld format–New–SEC
Oct 9, 2024BML Investment Partners, L.P.13G/AOld format–––SEC
Oct 9, 2024Acorn Bioventures, L.P.13GOld format–New–SEC
Oct 8, 2024New Enterprise Associates 15, L.P.13D/AOld format–––SEC
Sep 26, 2024Tang Capital Partners LP13GOld format–––SEC
May 21, 2024BML Investment Partners, L.P.13G/AOld format–––SEC
May 8, 2024New Enterprise Associates 15, L.P.13D/AOld format–––SEC
Feb 5, 2024Octagon Capital Advisors LP13GOld format–New–SEC
Jan 17, 2024BML Investment Partners, L.P.13GOld format–New–SEC
Dec 26, 2023Tang Capital Partners LP13DOld format–New–SEC
Dec 15, 2023Novo Holdings A/S13D/AOld format–––SEC

Form 144: proposed insider sales

1 notice from officers, directors and other affiliates planning to sell OnKure Therapeutics, Inc. shares, newest first.

Form 144 notices for OKUR
Filed (ET)SellerShares to sellMarket valuePlanned saleBrokerFiling
Jun 23, 20237:10 PM ETNovo Holdings A/S10% stockholder100.0K$735.0KJun 23, 2023Morgan Stanley & Co. LLCSEC