OnKure Therapeutics, Inc.
OKUR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001637715
In the last 90 days, OnKure Therapeutics, Inc. insiders filed 0 open-market purchases and 2 sales; 75 institutions reported holding it in 13F filings for Q2 2026, worth $159.0M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in OnKure Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 44
- +2 vs. Q3 2025
- Shares held
- 11.1M
- +836.4K (+8.2%) vs. Q3 2025
- Total value
- $32.0M
- +$3.87M (+13.8%) vs. Q3 2025
- New holders
- 8
- 10 more added
- Sold out
- 6
- 15 more reduced
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OKUR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 75 | $159.0M |
| Q1 2026 | 51 | $113.9M |
| Q4 2025 | 44 | $32.0M |
| Q3 2025 | 42 | $28.1M |
| Q2 2025 | 49 | $25.8M |
| Q1 2025 | 47 | $50.1M |
| Q4 2024 | 51 | $99.2M |
| Q3 2024 | 51 | $49.0M |
| Q2 2024 | 66 | $41.3M |
| Q1 2024 | 62 | $45.4M |
| Q4 2023 | 68 | $40.4M |
| Q3 2023 | 58 | $208.3M |
| Q2 2023 | 52 | $168.9M |
| Q1 2023 | 35 | $102.0M |
| Q4 2022 | 32 | $38.4M |
| Q3 2022 | 33 | $55.1M |
| Q2 2022 | 33 | $43.3M |
| Q1 2022 | 41 | $50.8M |
| Q4 2021 | 39 | $148.9M |
| Q3 2021 | 38 | $136.7M |
| Q2 2021 | 38 | $170.6M |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding OnKure Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Royal Bank of Canada | 102 | $0 | 0.00% | −88−46.3% | Reduced |
| Northwestern Mutual Wealth Management Co | 2 | $6 | 0.00% | +2 | New |
| Group One Trading, L.P. | 56 | $162 | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 109 | $316 | 0.00% | +9+9.0% | Added |
| Trust Co of Toledo NA | 136 | $394 | 0.00% | 00.0% | Unchanged |
| Bank of America Corp | 141 | $409 | 0.00% | −755−84.3% | Reduced |
| BNP Paribas Arbitrage, SA | 281 | $815 | 0.00% | −83−22.8% | Reduced |
| FMR LLC | 400 | $1.16K | 0.00% | +350+700.0% | Added |
| Torren Management, LLC | 504 | $1.46K | 0.00% | +504 | New |
| JPMorgan Chase & Co | 545 | $1.58K | 0.00% | +122+28.8% | Added |
| UBS Group AG | 1,208 | $3.50K | 0.00% | +1,003+489.3% | Added |
| Citigroup Inc | 3,729 | $10.8K | 0.00% | +405+12.2% | Added |
| Wells Fargo & Company | 11,000 | $31.9K | 0.00% | +1,500+15.8% | Added |
| Two Sigma Investments, LP | 11,320 | $32.8K | 0.00% | −14,115−55.5% | Reduced |
| XTX Topco Ltd | 17,801 | $51.6K | 0.00% | +17,801 | New |
| Jane Street Group, LLC | 19,414 | $56.3K | 0.00% | +19,414 | New |
| Bridgeway Capital Management, LLC | 19,500 | $56.5K | 0.00% | 00.0% | Unchanged |
| Northern Trust Corp | 19,903 | $57.7K | 0.00% | −2,607−11.6% | Reduced |
| HSBC Holdings PLC | 19,973 | $57.7K | 0.00% | +19,973 | New |
| Morgan Stanley | 24,962 | $72.4K | 0.00% | +7,748+45.0% | Added |
| Two Sigma Advisers, LP | 26,608 | $77.2K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 27,242 | $79.0K | 0.00% | +26,621+4,286.8% | Added |
| Aldebaran Capital, LLC | 41,284 | $119.7K | 0.11% | −2,713−6.2% | Reduced |
| Gsa Capital Partners LLP | 45,948 | $133.0K | 0.01% | −13,276−22.4% | Reduced |
| BlackRock, Inc. | 52,678 | $152.8K | 0.00% | −512,158−90.7% | Reduced |
| Sphera Funds Management Ltd. | 60,454 | $175.3K | 0.04% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 77,469 | $224.7K | 0.00% | −7,426−8.7% | Reduced |
| Aisling Capital Management LP | 88,607 | $257.0K | 0.05% | 00.0% | Unchanged |
| Rangeley Capital, LLC | 145,000 | $420.5K | 0.36% | −10,490−6.7% | Reduced |
| Kotler Kevin | 197,691 | $573.3K | 0.42% | +197,691 | New |
| Citadel Advisors LLC | 223,125 | $647.1K | 0.00% | −793,488−78.1% | Reduced |
| Renaissance Technologies LLC | 247,350 | $717.3K | 0.00% | +71,600+40.7% | Added |
| Carlyle Group Inc. | 269,895 | $771.9K | 0.01% | 00.0% | Unchanged |
| Cantor Fitzgerald, L. P. | 445,078 | $1.29M | 0.04% | −46,785−9.5% | Reduced |
| StepStone Group LP | 491,938 | $1.35M | 0.72% | 00.0% | Unchanged |
| NEA Management Company, LLC | 478,548 | $1.39M | 0.07% | 00.0% | Unchanged |
| Highbridge Capital Management LLC | 542,361 | $1.57M | 0.07% | −107,857−16.6% | Reduced |
| Vanguard Group Inc | 626,593 | $1.82M | 0.00% | −51,633−7.6% | Reduced |
| Vestal Point Capital, LP | 635,000 | $1.84M | 0.07% | 00.0% | Unchanged |
| Rosalind Advisors, Inc. | 730,488 | $2.12M | 0.81% | +730,488 | New |
| Shay Capital LLC | 780,861 | $2.26M | 0.37% | −137,073−14.9% | Reduced |
| Prosight Management, LP | 816,909 | $2.37M | 0.49% | +548,950+204.9% | Added |
| ADAR1 Capital Management, LLC | 1,014,158 | $2.94M | 0.22% | +1,014,158 | New |
| Acorn Capital Advisors, LLC | 2,839,674 | $8.24M | 2.79% | 00.0% | Unchanged |
| Tang Capital Management LLC | 0 | $0 | 0.00% | −116,395−100.0% | Sold out |
| China Universal Asset Management Co., Ltd. | 0 | $0 | 0.00% | −2,251−100.0% | Sold out |
| Tower Research Capital LLC (TRC) | 0 | $0 | 0.00% | −1,935−100.0% | Sold out |
| Mirae Asset Global Investments Co., Ltd. | 0 | $0 | 0.00% | −497−100.0% | Sold out |
| GF Fund Management Co. Ltd. | 0 | $0 | 0.00% | −271−100.0% | Sold out |
| MAI Capital Management | 0 | $0 | 0.00% | −6−100.0% | Sold out |