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OnKure Therapeutics, Inc.

OKUR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001637715

In the last 90 days, OnKure Therapeutics, Inc. insiders filed 0 open-market purchases and 2 sales; 75 institutions reported holding it in 13F filings for Q2 2026, worth $159.0M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in OnKure Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
42
−7 vs. Q2 2025
Shares held
10.2M
−559.5K (−5.2%) vs. Q2 2025
Total value
$28.1M
+$2.34M (+9.1%) vs. Q2 2025
New holders
1
15 more added
Sold out
8
13 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OKUR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 42 institutions
Q1 2021: 0 institutionsQ2 2021: 38 institutionsQ3 2021: 38 institutionsQ4 2021: 39 institutionsQ1 2022: 41 institutionsQ2 2022: 33 institutionsQ3 2022: 33 institutionsQ4 2022: 32 institutionsQ1 2023: 35 institutionsQ2 2023: 52 institutionsQ3 2023: 58 institutionsQ4 2023: 68 institutionsQ1 2024: 62 institutionsQ2 2024: 66 institutionsQ3 2024: 51 institutionsQ4 2024: 51 institutionsQ1 2025: 47 institutionsQ2 2025: 49 institutionsQ3 2025: 42 institutionsQ4 2025: 44 institutionsQ1 2026: 51 institutionsQ2 2026: 75 institutions
Value heldQ3 2025: $28.1M
Q1 2021: $0Q2 2021: $170.6MQ3 2021: $136.7MQ4 2021: $148.9MQ1 2022: $50.8MQ2 2022: $43.3MQ3 2022: $55.1MQ4 2022: $38.4MQ1 2023: $102.0MQ2 2023: $168.9MQ3 2023: $208.3MQ4 2023: $40.4MQ1 2024: $45.4MQ2 2024: $41.3MQ3 2024: $49.0MQ4 2024: $99.2MQ1 2025: $50.1MQ2 2025: $25.8MQ3 2025: $28.1MQ4 2025: $32.0MQ1 2026: $113.9MQ2 2026: $159.0M
Institutions holding OKUR and their total value by quarter
QuarterHoldersValue
Q2 202675$159.0M
Q1 202651$113.9M
Q4 202544$32.0M
Q3 202542$28.1M
Q2 202549$25.8M
Q1 202547$50.1M
Q4 202451$99.2M
Q3 202451$49.0M
Q2 202466$41.3M
Q1 202462$45.4M
Q4 202368$40.4M
Q3 202358$208.3M
Q2 202352$168.9M
Q1 202335$102.0M
Q4 202232$38.4M
Q3 202233$55.1M
Q2 202233$43.3M
Q1 202241$50.8M
Q4 202139$148.9M
Q3 202138$136.7M
Q2 202138$170.6M
Q1 20210$0

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding OnKure Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding OKUR in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Acorn Capital Advisors, LLC2,839,674$7.81M3.96%00.0%Unchanged
Citadel Advisors LLC1,016,613$2.80M0.00%−72,697−6.7%Reduced
Shay Capital LLC917,934$2.52M0.46%+135,888+17.4%Added
Vanguard Group Inc678,226$1.87M0.00%−28,507−4.0%Reduced
Highbridge Capital Management LLC650,218$1.79M0.09%−13,389−2.0%Reduced
Vestal Point Capital, LP635,000$1.75M0.08%00.0%Unchanged
BlackRock, Inc.564,836$1.55M0.00%+330.0%Added
StepStone Group LP491,938$1.35M0.64%00.0%Unchanged
Cantor Fitzgerald, L. P.491,863$1.35M0.03%−177,676−26.5%Reduced
NEA Management Company, LLC478,548$1.32M0.07%00.0%Unchanged
Carlyle Group Inc.269,895$742.2K0.02%00.0%Unchanged
Prosight Management, LP267,959$736.9K0.18%+108,267+67.8%Added
Renaissance Technologies LLC175,750$483.3K0.00%+53,114+43.3%Added
Rangeley Capital, LLC155,490$427.6K0.40%+125,588+420.0%Added
Tang Capital Management LLC116,395$320.1K0.01%−52,850−31.2%Reduced
Aisling Capital Management LP88,607$243.7K0.05%00.0%Unchanged
Geode Capital Management, LLC84,895$233.5K0.00%00.0%Unchanged
Sphera Funds Management Ltd.60,454$166.2K0.04%00.0%Unchanged
Gsa Capital Partners LLP59,224$163.0K0.01%+37,459+172.1%Added
Aldebaran Capital, LLC43,997$121.0K0.11%−176−0.4%Reduced
Two Sigma Advisers, LP26,608$73.2K0.00%−220−0.8%Reduced
Two Sigma Investments, LP25,435$69.9K0.00%−427−1.7%Reduced
Northern Trust Corp22,510$61.9K0.00%00.0%Unchanged
Bridgeway Capital Management, LLC19,500$53.6K0.00%−5,500−22.0%Reduced
Morgan Stanley17,214$47.3K0.00%+513+3.1%Added
Wells Fargo & Company9,500$26.1K0.00%+1,880+24.7%Added
Citigroup Inc3,324$9.14K0.00%+3,073+1,224.3%Added
China Universal Asset Management Co., Ltd.2,251$6.19K0.00%−325−12.6%Reduced
Tower Research Capital LLC (TRC)1,935$5.32K0.00%+103+5.6%Added
Bank of America Corp896$2.46K0.00%+48+5.7%Added
Barclays PLC621$1.71K0.00%−375−37.7%Reduced
Mirae Asset Global Investments Co., Ltd.497$1.37K0.00%+2+0.4%Added
JPMorgan Chase & Co423$1.16K0.00%+269+174.7%Added
BNP Paribas Arbitrage, SA364$1.00K0.00%+31+9.3%Added
Royal Bank of Canada190$1.00K0.00%−57−23.1%Reduced
GF Fund Management Co. Ltd.271$7450.00%−42−13.4%Reduced
UBS Group AG205$5640.00%+24+13.3%Added
Trust Co of Toledo NA136$3740.00%00.0%Unchanged
Advisor Group Holdings, Inc.100$2750.00%00.0%Unchanged
Group One Trading, L.P.56$1540.00%00.0%Unchanged
FMR LLC50$1380.00%+50New
MAI Capital Management6$170.00%00.0%Unchanged
Affinity Asset Advisors, LLC0$00.00%−347,990−100.0%Sold out
Deep Track Capital, LP0$00.00%−180,510−100.0%Sold out
Nantahala Capital Management, LLC0$00.00%−54,208−100.0%Sold out
Landscape Capital Management, L.L.C.0$00.00%−41,051−100.0%Sold out
Goldman Sachs Group Inc0$00.00%−14,964−100.0%Sold out
Bailard, Inc.0$00.00%−14,239−100.0%Sold out
XTX Topco Ltd0$00.00%−10,643−100.0%Sold out
ADAR1 Capital Management, LLC0$00.00%−10,000−100.0%Sold out