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OnKure Therapeutics, Inc.

OKUR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001637715

In the last 90 days, OnKure Therapeutics, Inc. insiders filed 0 open-market purchases and 2 sales; 75 institutions reported holding it in 13F filings for Q2 2026, worth $159.0M in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in OnKure Therapeutics, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
51
+1 vs. Q3 2024
Shares held
11.8M
−14.5M (−55.0%) vs. Q3 2024
Total value
$99.2M
+$54.6M (+122.1%) vs. Q3 2024
New holders
20
7 more added
Sold out
19
24 more reduced

1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OKUR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 51 institutions
Q1 2021: 0 institutionsQ2 2021: 38 institutionsQ3 2021: 38 institutionsQ4 2021: 39 institutionsQ1 2022: 41 institutionsQ2 2022: 33 institutionsQ3 2022: 33 institutionsQ4 2022: 32 institutionsQ1 2023: 35 institutionsQ2 2023: 52 institutionsQ3 2023: 58 institutionsQ4 2023: 68 institutionsQ1 2024: 62 institutionsQ2 2024: 66 institutionsQ3 2024: 51 institutionsQ4 2024: 51 institutionsQ1 2025: 47 institutionsQ2 2025: 49 institutionsQ3 2025: 42 institutionsQ4 2025: 44 institutionsQ1 2026: 51 institutionsQ2 2026: 75 institutions
Value heldQ4 2024: $99.2M
Q1 2021: $0Q2 2021: $170.6MQ3 2021: $136.7MQ4 2021: $148.9MQ1 2022: $50.8MQ2 2022: $43.3MQ3 2022: $55.1MQ4 2022: $38.4MQ1 2023: $102.0MQ2 2023: $168.9MQ3 2023: $208.3MQ4 2023: $40.4MQ1 2024: $45.4MQ2 2024: $41.3MQ3 2024: $49.0MQ4 2024: $99.2MQ1 2025: $50.1MQ2 2025: $25.8MQ3 2025: $28.1MQ4 2025: $32.0MQ1 2026: $113.9MQ2 2026: $159.0M
Institutions holding OKUR and their total value by quarter
QuarterHoldersValue
Q2 202675$159.0M
Q1 202651$113.9M
Q4 202544$32.0M
Q3 202542$28.1M
Q2 202549$25.8M
Q1 202547$50.1M
Q4 202451$99.2M
Q3 202451$49.0M
Q2 202466$41.3M
Q1 202462$45.4M
Q4 202368$40.4M
Q3 202358$208.3M
Q2 202352$168.9M
Q1 202335$102.0M
Q4 202232$38.4M
Q3 202233$55.1M
Q2 202233$43.3M
Q1 202241$50.8M
Q4 202139$148.9M
Q3 202138$136.7M
Q2 202138$170.6M
Q1 20210$0

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding OnKure Therapeutics, Inc.; share changes are against Q3 2024.

Institutions holding OKUR in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Cormorant Asset Management, LP1,837,739$15.8M0.87%+1,837,739New
Acorn Capital Advisors, LLC1,439,674$10.2M5.51%+1,439,674New
Citadel Advisors LLC1,074,314$8.78M0.01%+981,401+1,056.3%Added
Perceptive Advisors LLC1,004,439$8.64M0.24%+1,004,439New
Samsara BioCapital, LLC824,155$7.09M0.97%+824,155New
Vanguard Group Inc706,733$6.08M0.00%−175,371−19.9%Reduced
Vestal Point Capital, LP635,000$5.46M0.32%−164,400−20.6%Reduced
Deep Track Capital, LP523,989$4.51M0.17%+523,989New
StepStone Group LP491,938$4.23M3.70%+491,938New
NEA Management Company, LLC478,548$4.12M0.23%−4,306,946−90.0%Reduced
Highbridge Capital Management LLC399,743$3.44M0.13%−2,662,947−86.9%Reduced
Tang Capital Management LLC294,626$2.53M0.17%−2,651,634−90.0%Reduced
Carlyle Group Inc.269,895$2.33M0.06%−2,429,062−90.0%Reduced
Ikarian Capital, LLC253,754$2.18M0.62%−771,914−75.3%Reduced
Bank of America Corp249,642$2.15M0.00%+248,430+20,497.5%Added
Altium Capital Management LP218,386$1.88M0.58%+218,386New
Affinity Asset Advisors, LLC144,159$1.24M0.19%+144,159New
Millennium Management LLC144,099$1.24M0.00%+23,534+19.5%Added
BlackRock, Inc.94,017$808.5K0.00%−127,308−57.5%Reduced
Aisling Capital Management LP88,607$762.0K0.27%−797,468−90.0%Reduced
Sphera Funds Management Ltd.87,354$751.2K0.14%+87,354New
Boothbay Fund Management, LLC78,021$671.0K0.02%+78,021New
Geode Capital Management, LLC76,599$658.8K0.00%−137,900−64.3%Reduced
Prosight Management, LP63,754$548.3K0.15%+63,754New
Nantahala Capital Management, LLC54,777$471.1K0.03%−493,027−90.0%Reduced
Renaissance Technologies LLC47,450$408.1K0.00%−454,084−90.5%Reduced
Aldebaran Capital, LLC45,572$391.9K0.37%−406,544−89.9%Reduced
683 Capital Management, LLC43,371$373.0K0.04%+43,371New
Cantor Fitzgerald, L. P.35,700$293.9K0.01%+35,700New
Cubist Systematic Strategies, LLC20,549$176.7K0.00%+20,016+3,755.3%Added
Northern Trust Corp19,177$164.9K0.00%−24,836−56.4%Reduced
XTX Topco Ltd18,633$160.2K0.01%+18,633New
Shay Capital LLC15,016$129.1K0.03%−13,601−47.5%Reduced
Two Sigma Advisers, LP14,228$122.4K0.00%−212,072−93.7%Reduced
Walleye Capital LLC13,495$116.1K0.00%+13,495New
Omers Administration Corp12,100$104.1K0.00%+12,100New
Barclays PLC8,741$75.2K0.00%+8,513+3,733.8%Added
China Universal Asset Management Co., Ltd.2,683$23.1K0.00%−3,746−58.3%Reduced
UBS Group AG2,213$19.0K0.00%+1,024+86.1%Added
Tower Research Capital LLC (TRC)2,201$18.9K0.00%−18,110−89.2%Reduced
Wells Fargo & Company1,620$13.9K0.00%+420+35.0%Added
Morgan Stanley932$8.02K0.00%−63,591−98.6%Reduced
Mirae Asset Global Investments Co., Ltd.422$3.44K0.00%−787−65.1%Reduced
JPMorgan Chase & Co337$2.90K0.00%−7,331−95.6%Reduced
Group One Trading, L.P.289$2.48K0.00%−213−42.4%Reduced
GF Fund Management Co. Ltd.266$2.29K0.00%+266New
BNP Paribas Arbitrage, SA236$2.03K0.00%+236New
Advisor Group Holdings, Inc.152$1.31K0.00%−1,374−90.0%Reduced
Citigroup Inc102$8770.00%−3,452−97.1%Reduced
MAI Capital Management6$520.00%+6New
Royal Bank of Canada43$00.00%+43New
BML Capital Management, LLC0$00.00%−3,457,395−100.0%Sold out
Octagon Capital Advisors LP0$00.00%−2,250,000−100.0%Sold out
Acuitas Investments, LLC0$00.00%−403,148−100.0%Sold out
Two Sigma Investments, LP0$00.00%−135,326−100.0%Sold out
JBF Capital, Inc.0$00.00%−80,000−100.0%Sold out
Marquette Asset Management, LLC0$00.00%−73,770−100.0%Sold out
State Street Corp0$00.00%−71,636−100.0%Sold out
Bank of Montreal0$00.00%−60,617−100.0%Sold out
Ameriprise Financial Inc0$00.00%−49,824−100.0%Sold out
Commonwealth Equity Services, LLC0$00.00%−19,347−100.0%Sold out
Goldman Sachs Group Inc0$00.00%−14,135−100.0%Sold out
Dimensional Fund Advisors LP0$00.00%−13,327−100.0%Sold out
Squarepoint Ops LLC0$00.00%−11,034−100.0%Sold out
Point72 Asia (Singapore) Pte. Ltd.0$00.00%−9,668−100.0%Sold out
Russell Investments Group, Ltd.0$00.00%−9,520−100.0%Sold out
Catalyst Funds Management Pty Ltd0$00.00%−3,200−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−171−100.0%Sold out
Simplex Trading, LLC0$00.00%−100−100.0%Sold out
Cornerstone Planning Group LLC0$00.00%−53−100.0%Sold out
RiverVest Venture Management LLC––––Not filed