OnKure Therapeutics, Inc.
OKUR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001637715
In the last 90 days, OnKure Therapeutics, Inc. insiders filed 0 open-market purchases and 2 sales; 75 institutions reported holding it in 13F filings for Q2 2026, worth $159.0M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in OnKure Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 51
- +9 vs. Q4 2025
- Shares held
- 27.5M
- +17.3M (+169.0%) vs. Q4 2025
- Total value
- $113.9M
- +$84.3M (+285.1%) vs. Q4 2025
- New holders
- 18
- 12 more added
- Sold out
- 9
- 14 more reduced
2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OKUR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 75 | $159.0M |
| Q1 2026 | 51 | $113.9M |
| Q4 2025 | 44 | $32.0M |
| Q3 2025 | 42 | $28.1M |
| Q2 2025 | 49 | $25.8M |
| Q1 2025 | 47 | $50.1M |
| Q4 2024 | 51 | $99.2M |
| Q3 2024 | 51 | $49.0M |
| Q2 2024 | 66 | $41.3M |
| Q1 2024 | 62 | $45.4M |
| Q4 2023 | 68 | $40.4M |
| Q3 2023 | 58 | $208.3M |
| Q2 2023 | 52 | $168.9M |
| Q1 2023 | 35 | $102.0M |
| Q4 2022 | 32 | $38.4M |
| Q3 2022 | 33 | $55.1M |
| Q2 2022 | 33 | $43.3M |
| Q1 2022 | 41 | $50.8M |
| Q4 2021 | 39 | $148.9M |
| Q3 2021 | 38 | $136.7M |
| Q2 2021 | 38 | $170.6M |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding OnKure Therapeutics, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Citigroup Inc | 1 | $4 | 0.00% | −3,728−100.0% | Reduced |
| JPMorgan Chase & Co | 45 | $171 | 0.00% | −500−91.7% | Reduced |
| Advisor Group Holdings, Inc. | 90 | $372 | 0.00% | −19−17.4% | Reduced |
| Trust Co of Toledo NA | 136 | $563 | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 230 | $1.00K | 0.00% | +128+125.5% | Added |
| BNP Paribas Arbitrage, SA | 281 | $1.16K | 0.00% | 00.0% | Unchanged |
| Vanguard Global Advisers, LLC | 745 | $3.08K | 0.00% | +745 | New |
| UBS Group AG | 3,395 | $14.1K | 0.00% | +2,187+181.0% | Added |
| State Street Corp | 13,462 | $55.7K | 0.00% | +13,462 | New |
| Wells Fargo & Company | 13,500 | $55.9K | 0.00% | +2,500+22.7% | Added |
| Morgan Stanley | 14,327 | $59.3K | 0.00% | −10,635−42.6% | Reduced |
| Bridgeway Capital Management, LLC | 16,293 | $67.5K | 0.00% | −3,207−16.4% | Reduced |
| Northern Trust Corp | 19,903 | $82.4K | 0.00% | 00.0% | Unchanged |
| Gsa Capital Partners LLP | 22,224 | $92.0K | 0.01% | −23,724−51.6% | Reduced |
| Two Sigma Investments, LP | 24,262 | $100.4K | 0.00% | +12,942+114.3% | Added |
| Barclays PLC | 25,000 | $103.5K | 0.00% | −2,242−8.2% | Reduced |
| Jane Street Group, LLC | 26,812 | $111.0K | 0.00% | +7,398+38.1% | Added |
| Millennium Management LLC | 30,499 | $126.3K | 0.00% | +30,499 | New |
| XTX Topco Ltd | 34,129 | $141.3K | 0.00% | +16,328+91.7% | Added |
| Marshall Wace, LLP | 36,444 | $150.9K | 0.00% | +36,444 | New |
| HRT Financial LP | 37,055 | $153.0K | 0.00% | +37,055 | New |
| Citadel Advisors LLC | 37,587 | $155.6K | 0.00% | −185,538−83.2% | Reduced |
| Aldebaran Capital, LLC | 40,419 | $167.3K | 0.13% | −865−2.1% | Reduced |
| Vanguard Fiduciary Trust Co | 43,371 | $179.6K | 0.00% | +43,371 | New |
| GWM Advisors LLC | 44,551 | $184.4K | 0.00% | +44,551 | New |
| BlackRock, Inc. | 49,587 | $205.3K | 0.00% | −3,091−5.9% | Reduced |
| Aisling Capital Management LP | 88,607 | $366.8K | 0.08% | 00.0% | Unchanged |
| Rangeley Capital, LLC | 95,000 | $393.3K | 0.43% | −50,000−34.5% | Reduced |
| Geode Capital Management, LLC | 98,750 | $408.8K | 0.00% | +21,281+27.5% | Added |
| Cantor Fitzgerald, L. P. | 99,900 | $413.6K | 0.01% | −345,178−77.6% | Reduced |
| Shay Capital LLC | 132,219 | $547.4K | 0.08% | −648,642−83.1% | Reduced |
| Stonepine Capital Management, LLC | 132,578 | $548.9K | 0.48% | +132,578 | New |
| Sofinnova Investments, Inc. | 141,700 | $586.6K | 0.03% | +141,700 | New |
| DV Trading LLC | 240,963 | $997.6K | 0.09% | +240,963 | New |
| Affinity Asset Advisors, LLC | 240,963 | $997.6K | 0.06% | +240,963 | New |
| Carlyle Group Inc. | 269,895 | $1.12M | 0.01% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 377,250 | $1.56M | 0.00% | +129,900+52.5% | Added |
| Rosalind Advisors, Inc. | 443,763 | $1.84M | 0.75% | −286,725−39.3% | Reduced |
| NEA Management Company, LLC | 478,548 | $1.98M | 0.11% | 00.0% | Unchanged |
| Vanguard Capital Management LLC | 582,477 | $2.41M | 0.00% | +582,477 | New |
| Sio Capital Management, LLC | 1,078,965 | $4.47M | 0.64% | +1,078,965 | New |
| Adage Capital Partners GP, L.L.C. | 1,204,819 | $4.99M | 0.01% | +1,204,819 | New |
| Foresite Capital Management VI LLC | 1,445,783 | $5.99M | 1.30% | +1,445,783 | New |
| Vestal Point Capital, LP | 1,839,819 | $7.62M | 0.21% | +1,204,819+189.7% | Added |
| Vivo Capital, LLC | 1,927,710 | $7.98M | 0.66% | +1,927,710 | New |
| BVF Inc | 1,978,972 | $8.19M | 0.26% | +1,978,972 | New |
| Prosight Management, LP | 2,154,381 | $8.92M | 1.46% | +1,337,472+163.7% | Added |
| ADAR1 Capital Management, LLC | 2,434,941 | $10.1M | 0.61% | +1,420,783+140.1% | Added |
| StepStone Group LP | 2,660,612 | $11.0M | 5.31% | +2,168,674+440.8% | Added |
| Acorn Capital Advisors, LLC | 2,839,674 | $11.8M | 3.34% | 00.0% | Unchanged |
| Ra Capital Management, L.P. | 3,998,333 | $16.6M | 0.18% | +3,998,333 | New |
| Highbridge Capital Management LLC | 0 | $0 | 0.00% | −542,361−100.0% | Sold out |
| Sphera Funds Management Ltd. | 0 | $0 | 0.00% | −60,454−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −26,608−100.0% | Sold out |
| HSBC Holdings PLC | 0 | $0 | 0.00% | −19,973−100.0% | Sold out |
| Torren Management, LLC | 0 | $0 | 0.00% | −504−100.0% | Sold out |
| FMR LLC | 0 | $0 | 0.00% | −400−100.0% | Sold out |
| Bank of America Corp | 0 | $0 | 0.00% | −141−100.0% | Sold out |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −56−100.0% | Sold out |
| Northwestern Mutual Wealth Management Co | 0 | $0 | 0.00% | −2−100.0% | Sold out |
| Vanguard Group Inc | – | – | – | – | Not filed |
| Kotler Kevin | – | – | – | – | Not filed |