Milestone Pharmaceuticals Inc.
MIST- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001408443
No open-market purchases or sales by Milestone Pharmaceuticals Inc. insiders were filed in the last 90 days; 78 institutions reported holding it in 13F filings for Q2 2026, worth $66.4M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Milestone Pharmaceuticals Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 61
- +19 vs. Q2 2025
- Shares held
- 34.1M
- +22.3M (+188.9%) vs. Q2 2025
- Total value
- $68.3M
- +$45.4M (+197.8%) vs. Q2 2025
- New holders
- 26
- 18 more added
- Sold out
- 7
- 4 more reduced
1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MIST on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 78 | $66.4M |
| Q1 2026 | 87 | $47.2M |
| Q4 2025 | 80 | $70.7M |
| Q3 2025 | 61 | $68.3M |
| Q2 2025 | 43 | $22.9M |
| Q1 2025 | 43 | $9.46M |
| Q4 2024 | 47 | $57.9M |
| Q3 2024 | 43 | $43.6M |
| Q2 2024 | 40 | $39.9M |
| Q1 2024 | 43 | $56.4M |
| Q4 2023 | 40 | $29.7M |
| Q3 2023 | 39 | $60.7M |
| Q2 2023 | 48 | $59.0M |
| Q1 2023 | 50 | $85.5M |
| Q4 2022 | 56 | $96.9M |
| Q3 2022 | 47 | $198.7M |
| Q2 2022 | 29 | $127.2M |
| Q1 2022 | 28 | $135.1M |
| Q4 2021 | 28 | $132.6M |
| Q3 2021 | 27 | $113.9M |
| Q2 2021 | 28 | $110.8M |
| Q1 2021 | 34 | $117.4M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Milestone Pharmaceuticals Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| SBI Securities Co., Ltd. | 6 | $12 | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 1,077 | $2.15K | 0.00% | +1,077 | New |
| Wealthspire Advisors, LLC | 1,129 | $2.26K | 0.00% | +1,129 | New |
| US Bancorp | 3,200 | $6.40K | 0.00% | 00.0% | Unchanged |
| Group One Trading, L.P. | 7,022 | $14.0K | 0.00% | −24,594−77.8% | Reduced |
| Citigroup Inc | 7,812 | $15.6K | 0.00% | +7,812 | New |
| Journey Strategic Wealth LLC | 10,000 | $20.0K | 0.00% | −5,000−33.3% | Reduced |
| Ancora Advisors, LLC | 10,000 | $20.0K | 0.00% | 00.0% | Unchanged |
| Taylor Financial Group, Inc. | 10,000 | $20.0K | 0.01% | 00.0% | Unchanged |
| AQR Capital Management LLC | 10,000 | $20.0K | 0.00% | +10,000 | New |
| Secure Asset Management, LLC | 10,000 | $20.5K | 0.00% | +10,000 | New |
| Jones Financial Companies LLLP | 11,000 | $22.0K | 0.00% | 00.0% | Unchanged |
| Sapient Capital LLC | 12,200 | $24.8K | 0.00% | +12,200 | New |
| Cambridge Investment Research Advisors, Inc. | 12,698 | $25.0K | 0.00% | +12,698 | New |
| Beta Wealth Group, Inc. | 14,127 | $28.3K | 0.01% | 00.0% | Unchanged |
| Bank of America Corp | 16,052 | $32.1K | 0.00% | +16,044+200,550.0% | Added |
| Bay Rivers Group | 16,691 | $33.4K | 0.01% | +2,370+16.5% | Added |
| National Bank of Canada | 18,700 | $37.4K | 0.00% | 00.0% | Unchanged |
| Stephenson & Company, Inc. | 20,000 | $40.0K | 0.02% | +20,000 | New |
| State Street Corp | 22,220 | $44.4K | 0.00% | +3,974+21.8% | Added |
| Creative Planning | 23,410 | $46.8K | 0.00% | 00.0% | Unchanged |
| Mariner, LLC | 25,000 | $50.0K | 0.00% | +14,000+127.3% | Added |
| Safeguard Investment Advisory Group, LLC | 25,044 | $50.1K | 0.01% | 00.0% | Unchanged |
| Raymond James Financial Inc | 26,600 | $53.2K | 0.00% | −16,635−38.5% | Reduced |
| Federation des caisses Desjardins du Quebec | 29,781 | $59.6K | 0.00% | +16,781+129.1% | Added |
| Colony Group, LLC | 36,000 | $72.0K | 0.00% | 00.0% | Unchanged |
| Northern Trust Corp | 39,258 | $78.5K | 0.00% | −13,743−25.9% | Reduced |
| Simplex Trading, LLC | 66,920 | $133.0K | 0.00% | +66,920 | New |
| Geode Capital Management, LLC | 74,022 | $148.0K | 0.00% | +56,064+312.2% | Added |
| Cascades Capital Asset Management, LLC | 77,335 | $154.7K | 0.07% | +10,200+15.2% | Added |
| Gsa Capital Partners LLP | 78,747 | $157.0K | 0.01% | +78,747 | New |
| LPL Financial LLC | 95,300 | $190.6K | 0.00% | +84,250+762.4% | Added |
| Valeo Financial Advisors, LLC | 130,699 | $261.4K | 0.01% | 00.0% | Unchanged |
| HRT Financial LP | 138,812 | $277.0K | 0.00% | +138,812 | New |
| Royal Bank of Canada | 143,400 | $287.0K | 0.00% | +107,800+302.8% | Added |
| XTX Topco Ltd | 187,301 | $374.6K | 0.02% | +26,338+16.4% | Added |
| Aptus Capital Advisors, LLC | 210,200 | $420.4K | 0.00% | +210,200 | New |
| Guardian Wealth Advisors, LLC | 210,200 | $420.4K | 0.03% | +210,200 | New |
| Quadrature Capital Ltd | 223,470 | $448.1K | 0.01% | +223,470 | New |
| AMH Equity Ltd | 231,671 | $463.3K | 0.58% | +231,671 | New |
| Two Sigma Advisers, LP | 234,041 | $468.1K | 0.00% | +234,041 | New |
| Susquehanna International Group, LLP | 256,772 | $513.5K | 0.00% | +193,403+305.2% | Added |
| Goldman Sachs Group Inc | 356,567 | $713.1K | 0.00% | +237,118+198.5% | Added |
| UBS Group AG | 397,534 | $795.1K | 0.00% | +74,886+23.2% | Added |
| Millennium Management LLC | 401,559 | $803.1K | 0.00% | +401,559 | New |
| Jane Street Group, LLC | 408,492 | $817.0K | 0.00% | +376,559+1,179.2% | Added |
| Marshall Wace, LLP | 425,028 | $850.1K | 0.00% | +425,028 | New |
| Citadel Advisors LLC | 512,067 | $1.02M | 0.00% | +512,067 | New |
| Lion Point Capital, LP | 658,553 | $1.32M | 7.48% | +109,747+20.0% | Added |
| Two Sigma Investments, LP | 666,551 | $1.33M | 0.00% | +666,551 | New |
| Affinity Asset Advisors, LLC | 666,666 | $1.33M | 0.12% | +666,666 | New |
| Boxer Capital Management, LLC | 666,666 | $1.33M | 0.42% | +666,666 | New |
| Toronto Dominion Bank | 750,000 | $1.50M | 0.00% | 00.0% | Unchanged |
| Sphera Funds Management Ltd. | 820,000 | $1.64M | 0.39% | +820,000 | New |
| Pathstone Holdings, LLC | 1,000,000 | $2.00M | 0.01% | +1,000,000 | New |
| RTW Investments, LP | 2,506,102 | $5.01M | 0.06% | 00.0% | Unchanged |
| Simplify Asset Management Inc. | 2,832,974 | $5.67M | 0.11% | +1,842,974+186.2% | Added |
| Morgan Stanley | 2,969,067 | $5.94M | 0.00% | +2,148,646+261.9% | Added |
| OrbiMed Advisors LLC | 3,221,828 | $6.44M | 0.15% | +3,221,828 | New |
| Propel Bio Management, LLC | 5,124,890 | $10.2M | 10.26% | +3,333,333+186.1% | Added |
| Adage Capital Partners GP, L.L.C. | 6,976,000 | $14.0M | 0.02% | +6,976,000 | New |
| Alta Fundamental Advisers LLC | 0 | $0 | 0.00% | −1,398,977−100.0% | Sold out |
| BML Capital Management, LLC | 0 | $0 | 0.00% | −1,136,091−100.0% | Sold out |
| Bleichroeder LP | 0 | $0 | 0.00% | −500,000−100.0% | Sold out |
| Scientech Research LLC | 0 | $0 | 0.00% | −19,064−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −15,109−100.0% | Sold out |
| Mercer Global Advisors Inc | 0 | $0 | 0.00% | −15,100−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −14,761−100.0% | Sold out |
| Oliver Lagore Vanvalin Investment Group | – | – | – | – | Not filed |