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Madrigal Pharmaceuticals, Inc.

MDGL
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001157601

In the last 90 days, Madrigal Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 3 sales; 414 institutions reported holding it in 13F filings for Q2 2026, worth $12.7B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Madrigal Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
387
+44 vs. Q3 2025
Shares held
23.6M
+230.2K (+1.0%) vs. Q3 2025
Total value
$13.7B
+$3.02B (+28.2%) vs. Q3 2025
New holders
85
137 more added
Sold out
41
113 more reduced

9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MDGL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 387 institutions
Q1 2021: 137 institutionsQ2 2021: 151 institutionsQ3 2021: 133 institutionsQ4 2021: 144 institutionsQ1 2022: 140 institutionsQ2 2022: 138 institutionsQ3 2022: 135 institutionsQ4 2022: 189 institutionsQ1 2023: 223 institutionsQ2 2023: 208 institutionsQ3 2023: 206 institutionsQ4 2023: 226 institutionsQ1 2024: 266 institutionsQ2 2024: 257 institutionsQ3 2024: 257 institutionsQ4 2024: 283 institutionsQ1 2025: 321 institutionsQ2 2025: 305 institutionsQ3 2025: 352 institutionsQ4 2025: 387 institutionsQ1 2026: 380 institutionsQ2 2026: 414 institutions
Value heldQ4 2025: $13.7B
Q1 2021: $1.43BQ2 2021: $1.09BQ3 2021: $876.5MQ4 2021: $1.01BQ1 2022: $1.20BQ2 2022: $857.7MQ3 2022: $763.2MQ4 2022: $3.86BQ1 2023: $3.36BQ2 2023: $3.43BQ3 2023: $2.54BQ4 2023: $4.57BQ1 2024: $5.64BQ2 2024: $6.41BQ3 2024: $4.77BQ4 2024: $7.08BQ1 2025: $7.85BQ2 2025: $7.13BQ3 2025: $10.7BQ4 2025: $13.7BQ1 2026: $12.4BQ2 2026: $12.7B
Institutions holding MDGL and their total value by quarter
QuarterHoldersValue
Q2 2026414$12.7B
Q1 2026380$12.4B
Q4 2025387$13.7B
Q3 2025352$10.7B
Q2 2025305$7.13B
Q1 2025321$7.85B
Q4 2024283$7.08B
Q3 2024257$4.77B
Q2 2024257$6.41B
Q1 2024266$5.64B
Q4 2023226$4.57B
Q3 2023206$2.54B
Q2 2023208$3.43B
Q1 2023223$3.36B
Q4 2022189$3.86B
Q3 2022135$763.2M
Q2 2022138$857.7M
Q1 2022140$1.20B
Q4 2021144$1.01B
Q3 2021133$876.5M
Q2 2021151$1.09B
Q1 2021137$1.43B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Madrigal Pharmaceuticals, Inc.; share changes are against Q3 2025.

Institutions holding MDGL in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
CWM, LLC1,875$1.09M0.00%−485−20.6%Reduced
Seven Fleet Capital Management LP1,860$1.08M0.73%+1,860New
MML Investors Services, LLC1,668$971.3K0.00%+278+20.0%Added
Great West Life Assurance Co1,608$937.0K0.00%00.0%Unchanged
Kestra Advisory Services, LLC1,580$920.1K0.00%+13+0.8%Added
NEOS Investment Management LLC1,571$914.9K0.01%−50−3.1%Reduced
Tema ETFs LLC1,571$914.9K0.07%−50−3.1%Reduced
J. Safra Sarasin Holding AG1,546$900.3K0.01%−851−35.5%Reduced
Ameritas Investment Partners, Inc.1,536$894.5K0.03%−18−1.2%Reduced
AlTi Global, Inc.1,493$869.4K0.02%+1+0.1%Added
Xponance, Inc.1,463$852.0K0.01%+3+0.2%Added
Wealth Enhancement Advisory Services, LLC1,513$844.3K0.00%+805+113.7%Added
Cerity Partners LLC1,444$840.9K0.00%+481+49.9%Added
Public Employees Retirement Association of Colorado1,433$834.0K0.00%00.0%Unchanged
New York Life Investment Management LLC1,386$807.1K0.01%−224−13.9%Reduced
Sanctuary Advisors, LLC1,371$798.4K0.00%−94−6.4%Reduced
Two Sigma Securities, LLC1,336$778.0K0.11%+1,336New
Oppenheimer Asset Management Inc.1,313$764.6K0.01%+207+18.7%Added
O'Shaughnessy Asset Management, LLC1,283$747.1K0.00%+427+49.9%Added
JustInvest LLC1,249$727.3K0.01%+160+14.7%Added
Federation des caisses Desjardins du Quebec1,246$725.6K0.00%+162+14.9%Added
CIBC World Markets Corp1,231$716.9K0.00%+1,231New
B. Metzler seel. Sohn & Co. AG1,221$711.0K0.01%00.0%Unchanged
Cambridge Investment Research Advisors, Inc.1,198$698.0K0.00%−73−5.7%Reduced
Virtus Investment Advisers, Inc.1,194$695.3K0.19%−301−20.1%Reduced
HighTower Advisors, LLC1,173$683.1K0.00%+46+4.1%Added
Everhart Financial Group, Inc.1,163$677.3K0.06%+704+153.4%Added
Verity Asset Management, Inc.1,158$674.4K0.29%−102−8.1%Reduced
Captrust Financial Advisors1,131$658.6K0.00%+565+99.8%Added
HSBC Holdings PLC1,100$646.2K0.00%+1,100New
Landscape Capital Management, L.L.C.1,088$633.6K0.04%+78+7.7%Added
Pier 88 Investment Partners LLC1,080$628.9K0.14%+1,080New
Graham Capital Management, L.P.1,062$618.4K0.02%+1,062New
Natixis1,041$606.2K0.00%+1,041New
Cynosure Management, LLC1,025$596.9K0.06%+1,025New
Blair William & Co1,000$582.3K0.00%00.0%Unchanged
Optimize Financial Inc992$577.7K0.29%+12+1.2%Added
Atria Investments LLC988$575.4K0.01%−22−2.2%Reduced
Syon Capital LLC965$562.0K0.03%00.0%Unchanged
Baader Bank INC902$524.8K0.04%−1,033−53.4%Reduced
ADAR1 Capital Management, LLC895$521.2K0.04%−4,000−81.7%Reduced
PSP Research LLC892$519.4K0.45%+892New
Park Avenue Securities LLC858$499.0K0.00%+72+9.2%Added
Intrust Bank NA848$493.8K0.04%+174+25.8%Added
IFG Advisory, LLC844$491.5K0.02%+844New
QRG Capital Management, Inc.834$485.7K0.01%+63+8.2%Added
Mount Yale Investment Advisors, LLC824$479.8K0.02%+824New
CIBC Asset Management Inc816$475.2K0.00%+190+30.4%Added
PharVision Advisers, LLC813$473.4K0.24%+231+39.7%Added
Vestmark Advisory Solutions, Inc.806$469.4K0.01%+806New
Virginia Retirement Systems Et Al800$465.9K0.00%+800New
Chicago Partners Investment Group LLC961$461.7K0.01%−64−6.2%Reduced
Vise Technologies, Inc.769$447.8K0.01%+769New
Dorsey & Whitney Trust CO LLC752$437.9K0.02%00.0%Unchanged
Comerica Bank743$433.1K0.00%−16−2.1%Reduced
Eurizon Capital SGR S.p.A.729$424.8K0.00%+729New
Abel Hall, LLC710$413.5K0.10%+120+20.3%Added
Centaurus Financial, Inc.709$413.0K0.02%00.0%Unchanged
Miracle Mile Advisors, LLC703$409.4K0.01%00.0%Unchanged
Cannon Global Investment Management, LLC700$407.6K1.08%−100−12.5%Reduced
Glenmede Trust Co NA691$402.4K0.00%+691New
Swiss Life Asset Management Ltd690$401.8K0.00%+44+6.8%Added
Advisory Services Network, LLC658$383.2K0.01%+658New
Allspring Global Investments Holdings, LLC631$374.7K0.00%+631New
M&T Bank Corp629$365.9K0.00%+629New
Cary Street Partners Financial LLC628$365.7K0.01%+628New
JGP Global Gestao de Recursos Ltda.625$364.0K0.22%−417−40.0%Reduced
Tower Research Capital LLC (TRC)612$356.4K0.01%+255+71.4%Added
EP Wealth Advisors, LLC609$354.8K0.00%+609New
Amalgamated Bank584$340.0K0.00%−19−3.2%Reduced
Truist Financial Corp569$331.4K0.00%−34−5.6%Reduced
Integrated Investment Consultants, LLC567$330.2K0.06%00.0%Unchanged
Everence Capital Management Inc540$314.0K0.02%00.0%Unchanged
Private Advisor Group, LLC536$312.1K0.00%+536New
James J. Burns & Company, LLC532$309.8K0.04%+532New
Resources Investment Advisors, LLC.519$302.2K0.00%−97−15.7%Reduced
TCI Wealth Advisors, Inc.517$301.1K0.02%00.0%Unchanged
Wiley Bros.-Aintree Capital, LLC509$296.4K0.00%+509New
Soleus Capital Management, L.P.500$291.2K0.01%−67,836−99.3%Reduced
IFP Advisors, Inc461$268.5K0.01%+90+24.3%Added
GF Fund Management Co. Ltd.445$259.1K0.00%−35−7.3%Reduced
Kestra Investment Management, LLC445$259.1K0.01%+3+0.7%Added
US Bancorp441$256.8K0.00%+53+13.7%Added
Amundi437$254.5K0.00%+437New
SummitTX Capital, L.P.433$252.2K0.01%+433New
Skopos Labs, Inc.427$251.7K0.01%+427New
Prelude Capital Management, LLC430$250.4K0.02%+430New
Loring Wolcott & Coolidge Fiduciary Advisors LLP500$250.2K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC429$249.8K0.00%−6−1.4%Reduced
Ethic Inc.426$248.1K0.00%+426New
Quest Partners LLC420$244.6K0.01%+368+707.7%Added
Washington Trust Co420$244.6K0.01%+420New
KBC Group NV414$241.0K0.00%00.0%Unchanged
Bridgefront Capital, LLC393$228.9K0.06%−323−45.1%Reduced
Oppenheimer & Co Inc392$228.3K0.00%+392New
RSM US Wealth Management LLC381$222.4K0.00%+381New
Kozak & Associates, Inc.424$218.0K0.04%00.0%Unchanged
Arrowpoint Investment Partners (Singapore) Pte. Ltd.371$216.0K0.03%−421−53.2%Reduced
Callan Family Office, LLC366$213.1K0.00%+366New
Quantinno Capital Management LP364$212.0K0.00%+364New