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Madrigal Pharmaceuticals, Inc.

MDGL
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001157601

In the last 90 days, Madrigal Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 3 sales; 414 institutions reported holding it in 13F filings for Q2 2026, worth $12.7B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Madrigal Pharmaceuticals, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
380
0 vs. Q4 2025
Shares held
23.8M
+2.21M (+10.3%) vs. Q4 2025
Total value
$12.4B
−$105.9M (−0.8%) vs. Q4 2025
New holders
63
131 more added
Sold out
63
129 more reduced

7 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MDGL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 380 institutions
Q1 2021: 137 institutionsQ2 2021: 151 institutionsQ3 2021: 133 institutionsQ4 2021: 144 institutionsQ1 2022: 140 institutionsQ2 2022: 138 institutionsQ3 2022: 135 institutionsQ4 2022: 189 institutionsQ1 2023: 223 institutionsQ2 2023: 208 institutionsQ3 2023: 206 institutionsQ4 2023: 226 institutionsQ1 2024: 266 institutionsQ2 2024: 257 institutionsQ3 2024: 257 institutionsQ4 2024: 283 institutionsQ1 2025: 321 institutionsQ2 2025: 305 institutionsQ3 2025: 352 institutionsQ4 2025: 387 institutionsQ1 2026: 380 institutionsQ2 2026: 414 institutions
Value heldQ1 2026: $12.4B
Q1 2021: $1.43BQ2 2021: $1.09BQ3 2021: $876.5MQ4 2021: $1.01BQ1 2022: $1.20BQ2 2022: $857.7MQ3 2022: $763.2MQ4 2022: $3.86BQ1 2023: $3.36BQ2 2023: $3.43BQ3 2023: $2.54BQ4 2023: $4.57BQ1 2024: $5.64BQ2 2024: $6.41BQ3 2024: $4.77BQ4 2024: $7.08BQ1 2025: $7.85BQ2 2025: $7.13BQ3 2025: $10.7BQ4 2025: $13.7BQ1 2026: $12.4BQ2 2026: $12.7B
Institutions holding MDGL and their total value by quarter
QuarterHoldersValue
Q2 2026414$12.7B
Q1 2026380$12.4B
Q4 2025387$13.7B
Q3 2025352$10.7B
Q2 2025305$7.13B
Q1 2025321$7.85B
Q4 2024283$7.08B
Q3 2024257$4.77B
Q2 2024257$6.41B
Q1 2024266$5.64B
Q4 2023226$4.57B
Q3 2023206$2.54B
Q2 2023208$3.43B
Q1 2023223$3.36B
Q4 2022189$3.86B
Q3 2022135$763.2M
Q2 2022138$857.7M
Q1 2022140$1.20B
Q4 2021144$1.01B
Q3 2021133$876.5M
Q2 2021151$1.09B
Q1 2021137$1.43B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Madrigal Pharmaceuticals, Inc.; share changes are against Q4 2025.

Institutions holding MDGL in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Baker Bros. Advisors LP2,141,701$1.12B6.44%00.0%Unchanged
Janus Henderson Group PLC2,018,647$1.05B0.50%+433,804+27.4%Added
RTW Investments, LP1,993,687$1.04B10.38%00.0%Unchanged
Avoro Capital Advisors LLC1,818,181$951.8M9.38%+10,681+0.6%Added
BlackRock, Inc.1,559,965$816.6M0.01%−84,785−5.2%Reduced
Paulson & Co. Inc.1,392,188$728.8M23.42%−315,334−18.5%Reduced
Vanguard Portfolio Management LLC841,145$440.3M0.02%+841,145New
Vanguard Capital Management LLC827,144$433.0M0.01%+827,144New
Wellington Management Group LLP694,958$363.8M0.07%+233,556+50.6%Added
State Street Corp609,525$319.1M0.01%+26,522+4.5%Added
FMR LLC511,728$267.9M0.01%+72,330+16.5%Added
Geode Capital Management, LLC455,870$238.7M0.01%+4,127+0.9%Added
Citadel Advisors LLC453,843$237.6M0.17%+417,709+1,156.0%Added
William Blair Investment Management, LLC340,519$178.3M0.59%−13,701−3.9%Reduced
Invesco Ltd.329,519$172.5M0.02%−35,795−9.8%Reduced
Price T Rowe Associates Inc328,110$171.8M0.02%+14,451+4.6%Added
Polar Capital Holdings Plc289,310$151.4M0.66%+19,159+7.1%Added
Goldman Sachs Group Inc277,371$145.2M0.02%−28,476−9.3%Reduced
Armistice Capital, LLC264,583$138.5M4.57%−1,122−0.4%Reduced
Hood River Capital Management LLC249,511$130.6M1.31%+1,951+0.8%Added
Lord, Abbett & Co. LLC242,726$127.1M0.41%−2,070−0.8%Reduced
Point72 Asset Management, L.P.225,510$118.0M0.21%+99,075+78.4%Added
Charles Schwab Investment Management Inc216,720$113.4M0.02%−2,379−1.1%Reduced
Morgan Stanley191,294$100.1M0.01%+40,832+27.1%Added
Bank of America Corp189,527$99.2M0.01%−226,498−54.4%Reduced
Pictet Asset Management Holding SA187,240$97.9M0.10%+5,291+2.9%Added
Adage Capital Partners GP, L.L.C.185,331$97.0M0.15%+162,105+697.9%Added
Artisan Partners Limited Partnership183,540$96.1M0.16%−15,153−7.6%Reduced
Fiera Capital Corp174,011$91.1M0.31%+4,555+2.7%Added
Rock Springs Capital Management LP170,999$89.5M5.28%+31,381+22.5%Added
American Century Companies Inc163,933$85.8M0.04%−21,183−11.4%Reduced
Erste Asset Management GmbH160,210$81.0M0.75%+19,110+13.5%Added
Northern Trust Corp149,214$78.1M0.01%−2,588−1.7%Reduced
Alliancebernstein L.P.125,447$73.1M0.02%+103,535+472.5%Added
Bank of New York Mellon Corp135,908$71.1M0.01%−961−0.7%Reduced
Toronto Dominion Bank130,460$68.3M0.13%+130,460New
Vanguard Fiduciary Trust Co128,079$67.0M0.02%+128,079New
Woodline Partners LP125,899$65.9M0.25%+240+0.2%Added
UBS Group AG117,779$61.7M0.01%+15,138+14.7%Added
Driehaus Capital Management LLC110,960$58.1M0.43%−706−0.6%Reduced
Tri Locum Partners LP103,288$54.1M7.59%+17,265+20.1%Added
Ameriprise Financial Inc98,181$51.4M0.01%+68,894+235.2%Added
Deutsche Bank AG98,067$51.3M0.02%−94,042−49.0%Reduced
Westfield Capital Management Co LP94,813$49.6M0.21%+94,813New
Logos Global Management LP85,000$44.5M2.29%+85,000New
Candriam Luxembourg S.C.A.84,948$44.5M0.23%+21,042+32.9%Added
Alkeon Capital Management LLC80,000$41.9M0.19%−160,000−66.7%Reduced
New York State Common Retirement Fund75,129$39.3M0.05%−804−1.1%Reduced
Franklin Resources Inc74,041$38.8M0.01%−12,035−14.0%Reduced
Renaissance Technologies LLC71,870$37.6M0.06%−11,992−14.3%Reduced
Raymond James Financial Inc66,529$34.1M0.01%−195−0.3%Reduced
ArrowMark Colorado Holdings LLC62,441$32.7M0.87%−20,183−24.4%Reduced
Nuveen, LLC62,060$32.5M0.01%−56,303−47.6%Reduced
Voya Investment Management LLC59,971$31.4M0.03%−4,283−6.7%Reduced
BNP Paribas Arbitrage, SA57,177$29.9M0.02%−16,530−22.4%Reduced
Affinity Asset Advisors, LLC55,000$28.8M1.69%+23,869+76.7%Added
Squarepoint Ops LLC52,884$27.7M0.06%−22,050−29.4%Reduced
EULAV Asset Management49,000$25.7M0.82%00.0%Unchanged
Russell Investments Group, Ltd.44,504$23.3M0.03%−3,655−7.6%Reduced
Mirae Asset Global Investments Co., Ltd.40,926$21.4M0.06%−9,705−19.2%Reduced
Millennium Management LLC40,853$21.4M0.02%+33,875+485.5%Added
Schroder Investment Management Group39,852$20.1M0.02%+10,801+37.2%Added
Emerald Advisers, LLC37,654$19.7M0.62%−1,259−3.2%Reduced
Jane Street Group, LLC35,838$18.8M0.02%−57,276−61.5%Reduced
Groupama Asset Managment35,238$18.4M0.27%+4,618+15.1%Added
JPMorgan Chase & Co36,315$18.4M0.00%−3,764−9.4%Reduced
PFM Health Sciences, LP34,146$17.9M1.88%+26,888+370.5%Added
Rockefeller Capital Management L.P.33,849$17.7M0.03%+14,188+72.2%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.32,879$17.2M0.02%+17,532+114.2%Added
Wells Fargo & Company32,212$16.9M0.00%−11,245−25.9%Reduced
Segall Bryant & Hamill, LLC31,870$16.7M0.24%−1,650−4.9%Reduced
Vestal Point Capital, LP31,468$16.5M0.46%+31,468New
D. E. Shaw & Co., Inc.30,139$15.8M0.01%−58,415−66.0%Reduced
Gilder Gagnon Howe & Co LLC29,391$15.4M0.18%−4,077−12.2%Reduced
Swiss National Bank29,220$15.3M0.01%+640+2.2%Added
Connor, Clark & Lunn Investment Management Ltd.27,937$14.6M0.03%−30,358−52.1%Reduced
Citigroup Inc25,589$13.4M0.01%+2,262+9.7%Added
Integral Health Asset Management, LLC25,000$13.1M0.69%+25,000New
Clearbridge Investments, LLC24,447$12.8M0.01%+24,447New
SEI Investments Co24,198$12.7M0.01%+1,122+4.9%Added
Rhenman & Partners Asset Management AB24,050$12.6M1.55%+4,500+23.0%Added
UBS Asset Management Americas Inc23,796$12.5M0.00%−50−0.2%Reduced
California Public Employees Retirement System23,198$12.1M0.01%−8,088−25.9%Reduced
WCM Investment Management, LLC23,560$11.9M0.03%+6,306+36.5%Added
First Trust Advisors LP22,233$11.6M0.01%−2,586−10.4%Reduced
Susquehanna International Group, LLP22,216$11.6M0.02%−42,250−65.5%Reduced
Marshall Wace, LLP21,902$11.5M0.01%−17,676−44.7%Reduced
Rhumbline Advisers21,764$11.4M0.01%−1,927−8.1%Reduced
Tao Capital Management LP21,000$11.0M9.25%00.0%Unchanged
Universal- Beteiligungs- und Servicegesellschaft mbH18,452$9.66M0.02%−624−3.3%Reduced
California State Teachers Retirement System17,047$8.92M0.01%+3,039+21.7%Added
Federated Hermes, Inc.16,903$8.85M0.01%+578+3.5%Added
Emerald Mutual Fund Advisers Trust16,500$8.64M0.42%−8,496−34.0%Reduced
Manufacturers Life Insurance Company, The16,300$8.53M0.01%+248+1.5%Added
Assenagon Asset Management S.A.16,033$8.39M0.01%+10,643+197.5%Added
Silvercrest Asset Management Group LLC15,963$8.36M0.06%+15,963New
AQR Capital Management LLC15,953$8.35M0.00%+5,947+59.4%Added
Envestnet Asset Management Inc15,461$8.09M0.00%+89+0.6%Added
Cinctive Capital Management LP15,326$8.02M0.53%+11,639+315.7%Added
Vanguard Asset Management, Ltd14,090$7.38M0.01%+14,090New